Immunization with Mycobacterium vaccae induces an anti-inflammatory milieu in the CNS: Attenuation of stress-induced microglial priming, alarmins and anxiety-like behavior

Brain, Behavior, and Immunity

Volumn 73, Issue , 2018, Pages 352-363

  Frank, Matthew G ^a   Fonken, Laura K ^f   Dolzani, Samuel D ^a   Annis, Jessica L ^a   Siebler, Philip H ^a   Schmidt, Dominic ^a   Watkins, Linda R ^a   Maier, Steven F ^a   Lowry, Christopher A ^a,b,c,d,e  

^a UNIVERSITY OF COLORADO   (United States)

^b UNIVERSITY OF COLORADO SCHOOL OF MEDICINE   (United States)

^c UNIVERSITY OF COLORADO   (United States)

^d VETERANS AFFAIRS MEDICAL CENTER   (United States)

^e Military and Veteran Microbiome Consortium of Research and Education (MVM CORE)   (United States)

^f UNIVERSITY OF TEXAS AT AUSTIN   (United States)

Author keywords

Alarmin; Immunoregulation; M. vaccae; Microglia; Neuroinflammation; Stress

Indexed keywords

ALARMIN; CRYOPYRIN; HIGH MOBILITY GROUP B1 PROTEIN; INTERLEUKIN 4; MESSENGER RNA; PROBIOTIC AGENT; ANTIINFLAMMATORY AGENT; NLRP3 PROTEIN, RAT;

ADULT; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIINFLAMMATORY ACTIVITY; ANXIETY DISORDER; ARTICLE; BACTERIAL STRAIN; BRAIN REGION; CONTROLLED STUDY; DRUG EFFECT; DRUG EFFICACY; DRUG RESPONSE; GENE; GENE EXPRESSION; HIPPOCAMPUS; IMMUNIZATION; IMMUNOMODULATION; IMMUNOPHENOTYPING; IMMUNOREGULATION; MALE; MICROGLIA; MYCOBACTERIUM VACCAE; NFKBIA GENE; NLRP3 GENE; NONHUMAN; PRIORITY JOURNAL; RAT; ANIMAL; ANXIETY; CENTRAL NERVOUS SYSTEM; IMMUNOLOGY; INFLAMMATION; MENTAL STRESS; METABOLISM; MICROBIOLOGY; MYCOBACTERIUM; PHYSIOLOGY; PROCEDURES; SPRAGUE DAWLEY RAT; VACCINATION;

ALARMINS; ANIMALS; ANTI-INFLAMMATORY AGENTS; ANXIETY; CENTRAL NERVOUS SYSTEM; HIPPOCAMPUS; HMGB1 PROTEIN; IMMUNIZATION; INFLAMMATION; MALE; MICROGLIA; MYCOBACTERIUM; NLR FAMILY, PYRIN DOMAIN-CONTAINING 3 PROTEIN; RATS; RATS, SPRAGUE-DAWLEY; STRESS, PSYCHOLOGICAL; VACCINATION;

EID: 85047484763     PISSN: 08891591     EISSN: 10902139     Source Type: Journal    
DOI: 10.1016/j.bbi.2018.05.020     Document Type: Article

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