XIAP inhibition of β-cell apoptosis reduces the number of islets required to restore euglycemia in a syngeneic islet transplantation model

Islets

Volumn 2, Issue 1, 2010, Pages 18-23

  Plesner, Annette ^a   Soukhatcheva, Galina ^a   Korneluk, Robert G ^c   Verchere, C Bruce ^a,b  

^a UNIVERSITY OF BRITISH COLUMBIA   (Canada)

^b British Columbia Cancer   (Canada)

^c CHILDREN S HOSPITAL OF EASTERN ONTARIO   (Canada)

Author keywords

Apoptosis; Diabetes; Islet transplantation; Mouse; Suboptimal; XIAP

Indexed keywords

ADENOVIRUS VECTOR; BETA GALACTOSIDASE; INSULIN; X LINKED INHIBITOR OF APOPTOSIS; STREPTOZOCIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; APOPTOSIS; ARTICLE; CONTROLLED STUDY; DIABETES MELLITUS; DRUG MECHANISM; FEMALE; GLUCOSE BLOOD LEVEL; IMMUNOHISTOCHEMISTRY; ISOGRAFT; MOUSE; NICK END LABELING; NONHUMAN; PANCREAS ISLET BETA CELL; PROTEIN EXPRESSION; PROTEIN TRANSPORT; ANIMAL; BAGG ALBINO MOUSE; CELL COUNT; CYTOLOGY; EXPERIMENTAL DIABETES MELLITUS; GENE TRANSFER; GENETICS; HOMEOSTASIS; METABOLISM; METHODOLOGY; PANCREAS ISLET; PANCREAS ISLET TRANSPLANTATION; PATHOPHYSIOLOGY; PHYSIOLOGY;

ANIMALS; APOPTOSIS; BLOOD GLUCOSE; CELL COUNT; DIABETES MELLITUS, EXPERIMENTAL; FEMALE; GENE TRANSFER TECHNIQUES; HOMEOSTASIS; INSULIN-SECRETING CELLS; ISLETS OF LANGERHANS; ISLETS OF LANGERHANS TRANSPLANTATION; MICE; MICE, INBRED BALB C; MODELS, ANIMAL; STREPTOZOCIN; TRANSPLANTATION, ISOGENEIC; X-LINKED INHIBITOR OF APOPTOSIS PROTEIN;

EID: 85046915905     PISSN: 19382014     EISSN: 19382022     Source Type: Journal    
DOI: 10.4161/isl.2.1.9997     Document Type: Article

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