Islet protection and amelioration of type 2 diabetes mellitus by treatment with quercetin from the flowers of Edgeworthia gardneri

Drug Design, Development and Therapy

Volumn 12, Issue , 2018, Pages 955-966

  Zhuang, Manjiao ^a   Qiu, Honghong ^b   Li, Ping ^b   Hu, Lihua ^b   Wang, Yayu ^c   Rao, Lei ^b  

^a SICHUAN UNIVERSITY   (China)

^b CHENGDU MEDICAL COLLEGE   (China)

^c JINAN UNIVERSITY   (China)

Author keywords

Anti apoptosis; Edgeworthia gardneri; Insulin secretion; Quercetin; Type 2 diabetes mellitus

Indexed keywords

CALCIUM ION; CASPASE 12; CASPASE 3; CASPASE 9; GLIBENCLAMIDE; GLYCOGEN; INSULIN; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; PROTEIN BAX; PROTEIN BCL 2; QUERCETIN; TRIACYLGLYCEROL; ANTIOXIDANT; PALMITIC ACID;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; CALCIUM CELL LEVEL; CELL PROTECTION; CELL VIABILITY; CONTROLLED STUDY; DRUG MECHANISM; EDGEWORTHIA GARDNERI; ENZYME ACTIVATION; ENZYME PHOSPHORYLATION; FLOWER; GLUCOSE TOLERANCE; GLYCOGEN LIVER LEVEL; IN VIVO STUDY; INSULIN BLOOD LEVEL; INSULIN RELEASE; MEDICINAL PLANT; MITOCHONDRIAL MEMBRANE POTENTIAL; MOUSE; NON INSULIN DEPENDENT DIABETES MELLITUS; NONHUMAN; PANCREAS ISLET CELL; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION; TREATMENT DURATION; ANIMAL; ANTAGONISTS AND INHIBITORS; BLOOD; C57BL MOUSE; CELL CULTURE; CELL SURVIVAL; CHEMISTRY; CHINESE MEDICINE; DRUG EFFECT; EXPERIMENTAL DIABETES MELLITUS; HUMAN; ISOLATION AND PURIFICATION; METABOLISM; MOUSE MUTANT; THYMELAEACEAE;

ANIMALS; ANTIOXIDANTS; APOPTOSIS; CELL SURVIVAL; CELLS, CULTURED; DIABETES MELLITUS, EXPERIMENTAL; DIABETES MELLITUS, TYPE 2; FLOWERS; HUMANS; INSULIN; MEDICINE, CHINESE TRADITIONAL; MEMBRANE POTENTIAL, MITOCHONDRIAL; MICE; MICE, INBRED C57BL; MICE, OBESE; PALMITIC ACID; QUERCETIN; THYMELAEACEAE;

EID: 85046254995     PISSN: None     EISSN: 11778881     Source Type: Journal    
DOI: 10.2147/DDDT.S153898     Document Type: Article

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