Single-cell analysis of pyroptosis dynamics reveals conserved GSDMD-mediated subcellular events that precede plasma membrane rupture

Cell Death and Differentiation

Volumn 26, Issue 1, 2019, Pages 146-161

  de Vasconcelos, Nathalia M ^a,b   Van Opdenbosch, Nina ^a,b   Van Gorp, Hanne ^a,b   Parthoens, Eef ^b   Lamkanfi, Mohamed ^a,b,c  

^a GHENT UNIVERSITY   (Belgium)

^b DEPARTMENT OF PLANT SYSTEMS BIOLOGY   (Belgium)

^c JANSSEN RESEARCH FOUNDATION   (Belgium)

Author keywords

[No Author keywords available]

Indexed keywords

GASDERMIN D; MEMBRANE PROTEIN; MYOSIN II; PHOSPHATIDYLSERINE; UNCLASSIFIED DRUG; APOPTOSIS REGULATORY PROTEIN; GSDMD PROTEIN, HUMAN; INFLAMMASOME; PHOSPHATE BINDING PROTEIN; SIGNAL PEPTIDE;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; BONE MARROW DERIVED MACROPHAGE; C57BL 6 MOUSE; CELL DEATH; CELL DIFFERENTIATION; CELL MEMBRANE; CELL MEMBRANE PERMEABILITY; CELL STIMULATION; CELL SWELLING; CONFOCAL LASER SCANNING MICROSCOPY; CONTROLLED STUDY; CYTOLYSIS; MACROPHAGE; MEMBRANE RUPTURE; MITOCHONDRION; MOUSE; NECROPTOSIS; NONHUMAN; PRIORITY JOURNAL; PYROPTOSIS; SINGLE CELL ANALYSIS; ANIMAL; C57BL MOUSE; CYTOLOGY; DRUG EFFECT; GENETICS; IMMUNOLOGY; LYSOSOME; METABOLISM; NECROSIS;

ANIMALS; APOPTOSIS REGULATORY PROTEINS; CELL MEMBRANE; INFLAMMASOMES; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; LYSOSOMES; MACROPHAGES; MICE; MICE, INBRED C57BL; MITOCHONDRIA; NECROPTOSIS; NECROSIS; PHOSPHATE-BINDING PROTEINS; PHOSPHATIDYLSERINES; PYROPTOSIS; SINGLE-CELL ANALYSIS;

EID: 85045422074     PISSN: 13509047     EISSN: 14765403     Source Type: Journal    
DOI: 10.1038/s41418-018-0106-7     Document Type: Article

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