-
1
-
-
78751644099
-
Genetic variegation of clonal architecture and propagating cells in leukemia
-
Anderson, K. et al. Genetic variegation of clonal architecture and propagating cells in leukemia. Nature 469, 356-361 (2011).
-
(2011)
Nature
, vol.469
, pp. 356-361
-
-
Anderson, K.1
-
2
-
-
84863337617
-
Clonal architecture of secondary acute myeloid leukemia
-
Walter, M.J. et al. Clonal architecture of secondary acute myeloid leukemia. N. Engl. J. Med. 366, 1090-1098 (2012).
-
(2012)
N. Engl. J. Med.
, vol.366
, pp. 1090-1098
-
-
Walter, M.J.1
-
3
-
-
84864255882
-
The origin and evolution of mutations in acute myeloid leukemia
-
Welch, J.S. et al. The origin and evolution of mutations in acute myeloid leukemia. Cell 150, 264-278 (2012).
-
(2012)
Cell
, vol.150
, pp. 264-278
-
-
Welch, J.S.1
-
4
-
-
84863393080
-
Intratumor heterogeneity and branched evolution revealed by multiregion sequencing
-
Gerlinger, M. et al. Intratumor heterogeneity and branched evolution revealed by multiregion sequencing. N. Engl. J. Med. 366, 883-892 (2012).
-
(2012)
N. Engl. J. Med.
, vol.366
, pp. 883-892
-
-
Gerlinger, M.1
-
5
-
-
84896081834
-
Functional heterogeneity of genetically defined subclones in acute myeloid leukemia
-
Klco, J.M. et al. Functional heterogeneity of genetically defined subclones in acute myeloid leukemia. Cancer Cell 25, 379-392 (2014).
-
(2014)
Cancer Cell
, vol.25
, pp. 379-392
-
-
Klco, J.M.1
-
7
-
-
84877000591
-
Relapsed childhood acute lymphoblastic leukemia
-
Bhojwani, D. & Pui, C.H. Relapsed childhood acute lymphoblastic leukemia. Lancet Oncol. 14, e205-e217 (2013).
-
(2013)
Lancet Oncol.
, vol.14
, pp. e205-e217
-
-
Bhojwani, D.1
Pui, C.H.2
-
8
-
-
0022973268
-
Differentiation-linked leukemogenesis in lymphocytes
-
Greaves, M.F. Differentiation-linked leukemogenesis in lymphocytes. Science 234, 697-704 (1986).
-
(1986)
Science
, vol.234
, pp. 697-704
-
-
Greaves, M.F.1
-
9
-
-
33745940511
-
Biologic pathways associated with relapse in childhood acute lymphoblastic leukemia: A Children's Oncology Group study
-
Bhojwani, D. et al. Biologic pathways associated with relapse in childhood acute lymphoblastic leukemia: a Children's Oncology Group study. Blood 108, 711-717 (2006).
-
(2006)
Blood
, vol.108
, pp. 711-717
-
-
Bhojwani, D.1
-
10
-
-
57149118627
-
Genomic analysis of the clonal origins of relapsed acute lymphoblastic leukemia
-
Mullighan, C.G. et al. Genomic analysis of the clonal origins of relapsed acute lymphoblastic leukemia. Science 322, 1377-1380 (2008).
-
(2008)
Science
, vol.322
, pp. 1377-1380
-
-
Mullighan, C.G.1
-
11
-
-
81155123233
-
Integrated genomic analysis of relapsed childhood acute lymphoblastic leukemia reveals therapeutic strategies
-
Hogan, L.E. et al. Integrated genomic analysis of relapsed childhood acute lymphoblastic leukemia reveals therapeutic strategies. Blood 118, 5218-5226 (2011).
-
(2011)
Blood
, vol.118
, pp. 5218-5226
-
-
Hogan, L.E.1
-
12
-
-
43049139905
-
BCR-ABL1 lymphoblastic leukemia is characterized by the deletion of Ikaros
-
Mullighan, C.G. et al. BCR-ABL1 lymphoblastic leukemia is characterized by the deletion of Ikaros. Nature 453, 110-114 (2008).
-
(2008)
Nature
, vol.453
, pp. 110-114
-
-
Mullighan, C.G.1
-
13
-
-
47249099558
-
B lymphocytes: How they develop and function
-
LeBien, T.W. & Tedder, T.F. B lymphocytes: how they develop and function. Blood 112, 1570-1580 (2008).
-
(2008)
Blood
, vol.112
, pp. 1570-1580
-
-
LeBien, T.W.1
Tedder, T.F.2
-
14
-
-
84899574465
-
Single-cell trajectory detection uncovers progression and regulatory coordination in human B cell development
-
Bendall, S.C. et al. Single-cell trajectory detection uncovers progression and regulatory coordination in human B cell development. Cell 157, 714-725 (2014).
-
(2014)
Cell
, vol.157
, pp. 714-725
-
-
Bendall, S.C.1
-
15
-
-
84881669095
-
Predicting relapse risk in childhood acute lymphoblastic leukemia
-
Teachey, D.T. & Hunger, S.P. Predicting relapse risk in childhood acute lymphoblastic leukemia. Br. J. Haematol. 162, 606-620 (2013).
-
(2013)
Br. J. Haematol.
, vol.162
, pp. 606-620
-
-
Teachey, D.T.1
Hunger, S.P.2
-
16
-
-
84937604921
-
An interactive reference framework for modeling a dynamic immune system
-
Spitzer, M.H. et al. An interactive reference framework for modeling a dynamic immune system. Science 349, 1259425 (2015).
-
(2015)
Science
, vol.349
, pp. 1259425
-
-
Spitzer, M.H.1
-
17
-
-
84968624557
-
Automated mapping of phenotype space with single-cell data
-
Samusik, N., Good, Z., Spitzer, M.H., Davis, K.L. & Nolan, G.P. Automated mapping of phenotype space with single-cell data. Nat. Methods 13, 493-496 (2016).
-
(2016)
Nat. Methods
, vol.13
, pp. 493-496
-
-
Samusik, N.1
Good, Z.2
Spitzer, M.H.3
Davis, K.L.4
Nolan, G.P.5
-
18
-
-
84924258718
-
A continuous molecular roadmap to iPSC reprogramming through progression analysis of single-cell mass cytometry
-
Zunder, E.R., Lujan, E., Goltsev, Y., Wernig, M. & Nolan, G.P. A continuous molecular roadmap to iPSC reprogramming through progression analysis of single-cell mass cytometry. Cell. Stem Cell 16, 323-337 (2015).
-
(2015)
Cell. Stem Cell
, vol.16
, pp. 323-337
-
-
Zunder, E.R.1
Lujan, E.2
Goltsev, Y.3
Wernig, M.4
Nolan, G.P.5
-
19
-
-
84869049935
-
Cross-talk between ROR1 and the pre-B cell receptor promotes survival of t(1;19) acute lymphoblastic leukemia
-
Bicocca, V.T. et al. Cross-talk between ROR1 and the pre-B cell receptor promotes survival of t(1;19) acute lymphoblastic leukemia. Cancer Cell 22, 656-667 (2012).
-
(2012)
Cancer Cell
, vol.22
, pp. 656-667
-
-
Bicocca, V.T.1
-
20
-
-
0024421371
-
Prognostic importance of the pre-B cell immunophenotype and other presenting features in B lineage childhood acute lymphoblastic leukemia: A Pediatric Oncology Group study
-
Crist, W. et al. Prognostic importance of the pre-B cell immunophenotype and other presenting features in B lineage childhood acute lymphoblastic leukemia: a Pediatric Oncology Group study. Blood 74, 1252-1259 (1989).
-
(1989)
Blood
, vol.74
, pp. 1252-1259
-
-
Crist, W.1
-
21
-
-
34147224008
-
Genome-wide analysis of genetic alterations in acute lymphoblastic leukemia
-
Mullighan, C.G. et al. Genome-wide analysis of genetic alterations in acute lymphoblastic leukemia. Nature 446, 758-764 (2007).
-
(2007)
Nature
, vol.446
, pp. 758-764
-
-
Mullighan, C.G.1
-
22
-
-
77950537175
-
Regularization paths for generalized linear models via coordinate descent
-
Friedman, J., Hastie, T. & Tibshirani, R. Regularization paths for generalized linear models via coordinate descent. J. Stat. Softw. 33, 1-22 (2010).
-
(2010)
J. Stat. Softw.
, vol.33
, pp. 1-22
-
-
Friedman, J.1
Hastie, T.2
Tibshirani, R.3
-
23
-
-
0031015557
-
The lasso method for variable selection in the Cox model
-
Tibshirani, R. The lasso method for variable selection in the Cox model. Stat. Med. 16, 385-395 (1997).
-
(1997)
Stat. Med.
, vol.16
, pp. 385-395
-
-
Tibshirani, R.1
-
26
-
-
34250736743
-
Evaluating prediction rules for t-year survivors with censored regression models
-
Uno, H., Cai, T., Tian, L. & Wei, L.J. Evaluating prediction rules for t-year survivors with censored regression models. J. Am. Stat. Assoc. 102, 527-537 (2007).
-
(2007)
J. Am. Stat. Assoc.
, vol.102
, pp. 527-537
-
-
Uno, H.1
Cai, T.2
Tian, L.3
Wei, L.J.4
-
27
-
-
79954466848
-
On the C-statistics for evaluating overall adequacy of risk prediction procedures with censored survival data
-
Uno, H., Cai, T., Pencina, M.J., D'Agostino, R.B. & Wei, L.J. On the C-statistics for evaluating overall adequacy of risk prediction procedures with censored survival data. Statist. Med. 121, 1105-1117 (2011).
-
(2011)
Statist. Med.
, vol.121
, pp. 1105-1117
-
-
Uno, H.1
Cai, T.2
Pencina, M.J.3
D'Agostino, R.B.4
Wei, L.J.5
-
28
-
-
9044226139
-
Uniform approach to risk classification and treatment assignment for children with acute lymphoblastic leukemia
-
Smith, M. et al. Uniform approach to risk classification and treatment assignment for children with acute lymphoblastic leukemia. J. Clin. Oncol. 14, 18-24 (1996).
-
(1996)
J. Clin. Oncol.
, vol.14
, pp. 18-24
-
-
Smith, M.1
-
29
-
-
70449711125
-
Risk of relapse of childhood acute lymphoblastic leukemia is predicted by flow cytometric measurement of residual disease on day 15 bone marrow
-
Basso, G. et al. Risk of relapse of childhood acute lymphoblastic leukemia is predicted by flow cytometric measurement of residual disease on day 15 bone marrow. J. Clin. Oncol. 27, 5168-5174 (2009).
-
(2009)
J. Clin. Oncol.
, vol.27
, pp. 5168-5174
-
-
Basso, G.1
-
30
-
-
47049093795
-
Clinical significance of minimal residual disease in childhood acute lymphoblastic leukemia and its relationship to other prognostic factors: A Children's Oncology Group study
-
Borowitz, M.J. et al. Clinical significance of minimal residual disease in childhood acute lymphoblastic leukemia and its relationship to other prognostic factors: a Children's Oncology Group study. Blood 111, 5477-5485 (2008).
-
(2008)
Blood
, vol.111
, pp. 5477-5485
-
-
Borowitz, M.J.1
-
31
-
-
78649477601
-
Extensions of net reclassification improvement calculations to measure usefulness of new biomarkers
-
Pencina, M.J., D'Agostino, R.B. Sr. & Steyerberg, E.W. Extensions of net reclassification improvement calculations to measure usefulness of new biomarkers. Stat. Med. 30, 11-21 (2011).
-
(2011)
Stat. Med.
, vol.30
, pp. 11-21
-
-
Pencina, M.J.1
D'Agostino, R.B.2
Steyerberg, E.W.3
-
32
-
-
84878624975
-
A unified inference procedure for a class of measures to assess improvement in risk prediction systems with survival data
-
Uno, H., Tian, L., Cai, T., Kohane, I.S. & Wei, L.J. A unified inference procedure for a class of measures to assess improvement in risk prediction systems with survival data. Stat. Med. 32, 2430-2442 (2013).
-
(2013)
Stat. Med.
, vol.32
, pp. 2430-2442
-
-
Uno, H.1
Tian, L.2
Cai, T.3
Kohane, I.S.4
Wei, L.J.5
-
33
-
-
84914127300
-
Conditional density-based analysis of T cell signaling in single-cell data
-
Krishnaswamy, S. et al. Conditional density-based analysis of T cell signaling in single-cell data. Science 346, 1250689 (2014).
-
(2014)
Science
, vol.346
, pp. 1250689
-
-
Krishnaswamy, S.1
-
34
-
-
84893685103
-
Orchestrating B cell lymphopoiesis through interplay of IL7 receptor and preB cell receptor signaling
-
Clark, M.R., Mandal, M., Ochiai, K. & Singh, H. Orchestrating B cell lymphopoiesis through interplay of IL7 receptor and preB cell receptor signaling. Nat. Rev. Immunol. 14, 69-80 (2014).
-
(2014)
Nat. Rev. Immunol.
, vol.14
, pp. 69-80
-
-
Clark, M.R.1
Mandal, M.2
Ochiai, K.3
Singh, H.4
-
35
-
-
68949094024
-
MEK/ERK-mediated phosphorylation of Bim is required to ensure survival of T and B lymphocytes during mitogenic stimulation
-
O'Reilly, L.A. et al. MEK/ERK-mediated phosphorylation of Bim is required to ensure survival of T and B lymphocytes during mitogenic stimulation. J. Immunol. 183, 261-269 (2009).
-
(2009)
J. Immunol.
, vol.183
, pp. 261-269
-
-
O'Reilly, L.A.1
-
36
-
-
0034598746
-
Distinct types of diffuse large B cell lymphoma identified by gene expression profiling
-
Alizadeh, A.A. et al. Distinct types of diffuse large B cell lymphoma identified by gene expression profiling. Nature 403, 503-511 (2000).
-
(2000)
Nature
, vol.403
, pp. 503-511
-
-
Alizadeh, A.A.1
-
37
-
-
68149098480
-
Pre-B cell receptor-mediated cell cycle arrest in Philadelphia chromosome-positive acute lymphoblastic leukemia requires IKAROS function
-
Trageser, D. et al. Pre-B cell receptor-mediated cell cycle arrest in Philadelphia chromosome-positive acute lymphoblastic leukemia requires IKAROS function. J. Exp. Med. 206, 1739-1753 (2009).
-
(2009)
J. Exp. Med.
, vol.206
, pp. 1739-1753
-
-
Trageser, D.1
-
38
-
-
22344440682
-
Mimicry of a constitutively active pre-B cell receptor in acute lymphoblastic leukemia cells
-
Feldhahn, N. et al. Mimicry of a constitutively active pre-B cell receptor in acute lymphoblastic leukemia cells. J. Exp. Med. 201, 1837-1852 (2005).
-
(2005)
J. Exp. Med.
, vol.201
, pp. 1837-1852
-
-
Feldhahn, N.1
-
39
-
-
84961219276
-
PTEN opposes negative selection and enables oncogenic transformation of pre-B cells
-
Shojaee, S. et al. PTEN opposes negative selection and enables oncogenic transformation of pre-B cells. Nat. Med. 22, 379-387 (2016).
-
(2016)
Nat. Med.
, vol.22
, pp. 379-387
-
-
Shojaee, S.1
-
40
-
-
52949129499
-
Single-cell profiling identifies aberrant STAT5 activation in myeloid malignancies with specific clinical and biologic correlates
-
Kotecha, N. et al. Single-cell profiling identifies aberrant STAT5 activation in myeloid malignancies with specific clinical and biologic correlates. Cancer Cell 14, 335-343 (2008).
-
(2008)
Cancer Cell
, vol.14
, pp. 335-343
-
-
Kotecha, N.1
-
41
-
-
84856757544
-
Decoupling of tumor-initiating activity from stable immunophenotype in HoxA9-Meis1-driven AML
-
Gibbs, K.D. Jr. et al. Decoupling of tumor-initiating activity from stable immunophenotype in HoxA9-Meis1-driven AML. Cell. Stem Cell 10, 210-217 (2012).
-
(2012)
Cell. Stem Cell
, vol.10
, pp. 210-217
-
-
Gibbs, K.D.1
-
42
-
-
77955643156
-
B cell signaling networks reveal a negative prognostic human lymphoma cell subset that emerges during tumor progression
-
Irish, J.M. et al. B cell signaling networks reveal a negative prognostic human lymphoma cell subset that emerges during tumor progression. Proc. Natl. Acad. Sci. USA 107, 12747-12754 (2010).
-
(2010)
Proc. Natl. Acad. Sci. USA
, vol.107
, pp. 12747-12754
-
-
Irish, J.M.1
-
43
-
-
3242683662
-
Single cell profiling of potentiated phospho-protein networks in cancer cells
-
Irish, J.M. et al. Single cell profiling of potentiated phospho-protein networks in cancer cells. Cell 118, 217-228 (2004).
-
(2004)
Cell
, vol.118
, pp. 217-228
-
-
Irish, J.M.1
-
44
-
-
84934442835
-
Data-driven phenotypic dissection of AML reveals progenitor-like cells that correlate with prognosis
-
Levine, J.H. et al. Data-driven phenotypic dissection of AML reveals progenitor-like cells that correlate with prognosis. Cell 162, 184-197 (2015).
-
(2015)
Cell
, vol.162
, pp. 184-197
-
-
Levine, J.H.1
-
45
-
-
77951441599
-
Molecular response to treatment redefines all prognostic factors in children and adolescents with B cell precursor acute lymphoblastic leukemia: Results in 3,184 patients of the AIEOP-BFM ALL 2000 study
-
Conter, V. et al. Molecular response to treatment redefines all prognostic factors in children and adolescents with B cell precursor acute lymphoblastic leukemia: results in 3,184 patients of the AIEOP-BFM ALL 2000 study. Blood 115, 3206-3214 (2010).
-
(2010)
Blood
, vol.115
, pp. 3206-3214
-
-
Conter, V.1
-
46
-
-
85045280855
-
-
WHO Expert Committee (Second Meeting of the Subcommittee of the Expert Committee on the Selection and Use of Essential Medicines) 1-11 (World Health Organization, Geneva)
-
WHO Expert Committee. Acute lymphoblastic leukemia in children: a brief review of the internationally available protocols. (Second Meeting of the Subcommittee of the Expert Committee on the Selection and Use of Essential Medicines) 1-11 (World Health Organization, Geneva, 2008).
-
(2008)
Acute Lymphoblastic Leukemia in Children: A Brief Review of the Internationally Available Protocols
-
-
-
47
-
-
79955750055
-
Single-cell mass cytometry of differential immune and drug responses across a human hematopoietic continuum
-
Bendall, S.C. et al. Single-cell mass cytometry of differential immune and drug responses across a human hematopoietic continuum. Science 332, 687-696 (2011).
-
(2011)
Science
, vol.332
, pp. 687-696
-
-
Bendall, S.C.1
-
48
-
-
84861347894
-
A platinum-based covalent viability reagent for single-cell mass cytometry
-
Fienberg, H.G., Simonds, E.F., Fantl, W.J., Nolan, G.P. & Bodenmiller, B. A platinum-based covalent viability reagent for single-cell mass cytometry. Cytometry A 81, 467-475 (2012).
-
(2012)
Cytometry A
, vol.81
, pp. 467-475
-
-
Fienberg, H.G.1
Simonds, E.F.2
Fantl, W.J.3
Nolan, G.P.4
Bodenmiller, B.5
-
49
-
-
84924234154
-
Palladium-based mass tag cell barcoding with a doublet-filtering scheme and single-cell deconvolution algorithm
-
Zunder, E.R. et al. Palladium-based mass tag cell barcoding with a doublet-filtering scheme and single-cell deconvolution algorithm. Nat. Protoc. 10, 316-333 (2015).
-
(2015)
Nat. Protoc.
, vol.10
, pp. 316-333
-
-
Zunder, E.R.1
-
50
-
-
84876799270
-
Normalization of mass cytometry data with bead standards
-
Finck, R. et al. Normalization of mass cytometry data with bead standards. Cytometry A 83, 483-494 (2013).
-
(2013)
Cytometry A
, vol.83
, pp. 483-494
-
-
Finck, R.1
|