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Volumn 9, Issue MAR, 2018, Pages

The contribution of non-professional antigen-presenting cells to immunity and tolerance in the liver

Author keywords

Antigen presentation; CD1d; Immunoregulation; Liver; Tolerance

Indexed keywords


EID: 85044867050     PISSN: None     EISSN: 16643224     Source Type: Journal    
DOI: 10.3389/fimmu.2018.00635     Document Type: Review
Times cited : (59)

References (92)
  • 1
    • 84911887407 scopus 로고    scopus 로고
    • Immune tolerance in liver disease
    • Crispe IN. Immune tolerance in liver disease. Hepatology (2014) 60(6):2109-17. doi:10.1002/hep.27254
    • (2014) Hepatology , vol.60 , Issue.6 , pp. 2109-2117
    • Crispe, I.N.1
  • 2
    • 84925461550 scopus 로고    scopus 로고
    • The role of hepatic immune regulation in systemic immunity to viral infection
    • Knolle PA, Bottcher J, Huang LR. The role of hepatic immune regulation in systemic immunity to viral infection. Med Microbiol Immunol (2015) 204(1):21-7. doi:10.1007/s00430-014-0371-0
    • (2015) Med Microbiol Immunol , vol.204 , Issue.1 , pp. 21-27
    • Knolle, P.A.1    Bottcher, J.2    Huang, L.R.3
  • 3
    • 84953368398 scopus 로고    scopus 로고
    • Immunity, tolerance and autoimmunity in the liver: a comprehensive review
    • Doherty DG. Immunity, tolerance and autoimmunity in the liver: a comprehensive review. J Autoimmun (2016) 66:60-75. doi:10.1016/j.jaut.2015.08.020
    • (2016) J Autoimmun , vol.66 , pp. 60-75
    • Doherty, D.G.1
  • 4
    • 78650779272 scopus 로고    scopus 로고
    • Regulation of hepatic blood flow: the hepatic arterial buffer response revisited
    • Eipel C, Abshagen K, Vollmar B. Regulation of hepatic blood flow: the hepatic arterial buffer response revisited. World J Gastroenterol (2010) 16(48):6046-57. doi:10.3748/wjg.v16.i48.6046
    • (2010) World J Gastroenterol , vol.16 , Issue.48 , pp. 6046-6057
    • Eipel, C.1    Abshagen, K.2    Vollmar, B.3
  • 5
    • 84886646838 scopus 로고    scopus 로고
    • Immune surveillance by the liver
    • Jenne CN, Kubes P. Immune surveillance by the liver. Nat Immunol (2013) 14(10):996-1006. doi:10.1038/ni.2691
    • (2013) Nat Immunol , vol.14 , Issue.10 , pp. 996-1006
    • Jenne, C.N.1    Kubes, P.2
  • 6
    • 33847732713 scopus 로고    scopus 로고
    • Activation of vascular adhesion protein-1 on liver endothelium results in an NF-kappaB-dependent increase in lymphocyte adhesion
    • Lalor PF, Sun PJ, Weston CJ, Martin-Santos A, Wakelam MJ, Adams DH. Activation of vascular adhesion protein-1 on liver endothelium results in an NF-kappaB-dependent increase in lymphocyte adhesion. Hepatology (2007) 45(2):465-74. doi:10.1002/hep.21497
    • (2007) Hepatology , vol.45 , Issue.2 , pp. 465-474
    • Lalor, P.F.1    Sun, P.J.2    Weston, C.J.3    Martin-Santos, A.4    Wakelam, M.J.5    Adams, D.H.6
  • 8
    • 0022198149 scopus 로고
    • Retinoids, retinoid-binding proteins, and retinyl palmitate hydrolase distributions in different types of rat liver cells
    • Blaner WS, Hendriks HF, Brouwer A, de Leeuw AM, Knook DL, Goodman DS. Retinoids, retinoid-binding proteins, and retinyl palmitate hydrolase distributions in different types of rat liver cells. J Lipid Res (1985) 26(10):1241-51.
    • (1985) J Lipid Res , vol.26 , Issue.10 , pp. 1241-1251
    • Blaner, W.S.1    Hendriks, H.F.2    Brouwer, A.3    de Leeuw, A.M.4    Knook, D.L.5    Goodman, D.S.6
  • 9
    • 0034808310 scopus 로고    scopus 로고
    • History, heterogeneity, developmental biology, and functions of quiescent hepatic stellate cells
    • Geerts A. History, heterogeneity, developmental biology, and functions of quiescent hepatic stellate cells. Semin Liver Dis (2001) 21(3):311-35. doi:10.1055/s-2001-17550
    • (2001) Semin Liver Dis , vol.21 , Issue.3 , pp. 311-335
    • Geerts, A.1
  • 10
    • 1842427904 scopus 로고    scopus 로고
    • The maintenance and generation of membrane polarity in hepatocytes
    • Wang L, Boyer JL. The maintenance and generation of membrane polarity in hepatocytes. Hepatology (2004) 39(4):892-9. doi:10.1002/hep.20039
    • (2004) Hepatology , vol.39 , Issue.4 , pp. 892-899
    • Wang, L.1    Boyer, J.L.2
  • 11
    • 84946763639 scopus 로고    scopus 로고
    • Multimodal super-resolution optical microscopy visualizes the close connection between membrane and the cytoskeleton in liver sinusoidal endothelial cell fenestrations
    • Mönkemöller V, Oie C, Hubner W, Huser T, McCourt P. Multimodal super-resolution optical microscopy visualizes the close connection between membrane and the cytoskeleton in liver sinusoidal endothelial cell fenestrations. Sci Rep (2015) 5:16279. doi:10.1038/srep16279
    • (2015) Sci Rep , vol.5 , pp. 16279
    • Mönkemöller, V.1    Oie, C.2    Hubner, W.3    Huser, T.4    McCourt, P.5
  • 12
    • 85008219277 scopus 로고    scopus 로고
    • Liver sinusoidal endothelial cells: physiology and role in liver diseases
    • Poisson J, Lemoinne S, Boulanger C, Durand F, Moreau R, Valla D, et al. Liver sinusoidal endothelial cells: physiology and role in liver diseases. J Hepatol (2017) 66(1):212-27. doi:10.1016/j.jhep.2016.07.009
    • (2017) J Hepatol , vol.66 , Issue.1 , pp. 212-227
    • Poisson, J.1    Lemoinne, S.2    Boulanger, C.3    Durand, F.4    Moreau, R.5    Valla, D.6
  • 13
    • 0023897945 scopus 로고
    • Binding, uptake, and transcytosis of ligands for mannose-specific receptors in rat liver: an electron microscopic study
    • Kempka G, Kolb-Bachofen V. Binding, uptake, and transcytosis of ligands for mannose-specific receptors in rat liver: an electron microscopic study. Exp Cell Res (1988) 176(1):38-48. doi:10.1016/0014-4827(88)90118-8
    • (1988) Exp Cell Res , vol.176 , Issue.1 , pp. 38-48
    • Kempka, G.1    Kolb-Bachofen, V.2
  • 14
    • 0141644236 scopus 로고    scopus 로고
    • Pathways for movement of fluid and cells from hepatic sinusoids to the portal lymphatic vessels and subcapsular region in rat livers
    • Ohtani Y, Wang BJ, Poonkhum R, Ohtani O. Pathways for movement of fluid and cells from hepatic sinusoids to the portal lymphatic vessels and subcapsular region in rat livers. Arch Histol Cytol (2003) 66(3):239-52. doi:10.1679/aohc.66.239
    • (2003) Arch Histol Cytol , vol.66 , Issue.3 , pp. 239-252
    • Ohtani, Y.1    Wang, B.J.2    Poonkhum, R.3    Ohtani, O.4
  • 15
    • 45849098736 scopus 로고    scopus 로고
    • Lymph circulation in the liver
    • Ohtani O, Ohtani Y. Lymph circulation in the liver. Anat Rec (Hoboken) (2008) 291(6):643-52. doi:10.1002/ar.20681
    • (2008) Anat Rec (Hoboken) , vol.291 , Issue.6 , pp. 643-652
    • Ohtani, O.1    Ohtani, Y.2
  • 16
    • 85006117077 scopus 로고    scopus 로고
    • The role of lymphatic endothelial cells in liver injury and tumor development
    • Lukacs-Kornek V. The role of lymphatic endothelial cells in liver injury and tumor development. Front Immunol (2016) 7:548. doi:10.3389/fimmu.2016.00548
    • (2016) Front Immunol , vol.7 , pp. 548
    • Lukacs-Kornek, V.1
  • 17
    • 84960367509 scopus 로고    scopus 로고
    • Staying local-antigen presentation in the liver
    • Knolle PA. Staying local-antigen presentation in the liver. Curr Opin Immunol (2016) 40:36-42. doi:10.1016/j.coi.2016.02.009
    • (2016) Curr Opin Immunol , vol.40 , pp. 36-42
    • Knolle, P.A.1
  • 18
    • 84966270820 scopus 로고    scopus 로고
    • Presentation of hepatocellular antigens
    • Grakoui A, Crispe IN. Presentation of hepatocellular antigens. Cell Mol Immunol (2016) 13(3):293-300. doi:10.1038/cmi.2015.109
    • (2016) Cell Mol Immunol , vol.13 , Issue.3 , pp. 293-300
    • Grakoui, A.1    Crispe, I.N.2
  • 19
    • 0024501251 scopus 로고
    • Extremely rapid endocytosis mediated by the mannose receptor of sinusoidal endothelial rat liver cells
    • Magnusson S, Berg T. Extremely rapid endocytosis mediated by the mannose receptor of sinusoidal endothelial rat liver cells. Biochem J (1989) 257(3):651-6. doi:10.1042/bj2570651
    • (1989) Biochem J , vol.257 , Issue.3 , pp. 651-656
    • Magnusson, S.1    Berg, T.2
  • 20
    • 80053309337 scopus 로고    scopus 로고
    • Cross-presentation of antigen by diverse subsets of murine liver cells
    • Ebrahimkhani MR, Mohar I, Crispe IN. Cross-presentation of antigen by diverse subsets of murine liver cells. Hepatology (2011) 54(4):1379-87. doi:10.1002/hep.24508
    • (2011) Hepatology , vol.54 , Issue.4 , pp. 1379-1387
    • Ebrahimkhani, M.R.1    Mohar, I.2    Crispe, I.N.3
  • 21
    • 9644302323 scopus 로고    scopus 로고
    • Stabilin-1 and stabilin-2 are both directed into the early endocytic pathway in hepatic sinusoidal endothelium via interactions with clathrin/AP-2, independent of ligand binding
    • Hansen B, Longati P, Elvevold K, Nedredal GI, Schledzewski K, Olsen R, et al. Stabilin-1 and stabilin-2 are both directed into the early endocytic pathway in hepatic sinusoidal endothelium via interactions with clathrin/AP-2, independent of ligand binding. Exp Cell Res (2005) 303(1):160-73. doi:10.1016/j.yexcr.2004.09.017
    • (2005) Exp Cell Res , vol.303 , Issue.1 , pp. 160-173
    • Hansen, B.1    Longati, P.2    Elvevold, K.3    Nedredal, G.I.4    Schledzewski, K.5    Olsen, R.6
  • 22
    • 81355147444 scopus 로고    scopus 로고
    • Rat liver sinusoidal endothelial cells (LSECs) express functional low density lipoprotein receptor-related protein-1 (LRP-1)
    • Oie CI, Appa RS, Hilden I, Petersen HH, Gruhler A, Smedsrod B, et al. Rat liver sinusoidal endothelial cells (LSECs) express functional low density lipoprotein receptor-related protein-1 (LRP-1). J Hepatol (2011) 55(6):1346-52. doi:10.1016/j.jhep.2011.03.013
    • (2011) J Hepatol , vol.55 , Issue.6 , pp. 1346-1352
    • Oie, C.I.1    Appa, R.S.2    Hilden, I.3    Petersen, H.H.4    Gruhler, A.5    Smedsrod, B.6
  • 23
    • 84958567990 scopus 로고    scopus 로고
    • Scavenger receptor B1, the HDL receptor, is expressed abundantly in liver sinusoidal endothelial cells
    • Ganesan LP, Mates JM, Cheplowitz AM, Avila CL, Zimmerer JM, Yao Z, et al. Scavenger receptor B1, the HDL receptor, is expressed abundantly in liver sinusoidal endothelial cells. Sci Rep (2016) 6:20646. doi:10.1038/srep20646
    • (2016) Sci Rep , vol.6 , pp. 20646
    • Ganesan, L.P.1    Mates, J.M.2    Cheplowitz, A.M.3    Avila, C.L.4    Zimmerer, J.M.5    Yao, Z.6
  • 24
    • 78650792665 scopus 로고    scopus 로고
    • Role of liver sinusoidal endothelial cells and stabilins in elimination of oxidized low-density lipoproteins
    • Li R, Oteiza A, Sorensen KK, McCourt P, Olsen R, Smedsrod B, et al. Role of liver sinusoidal endothelial cells and stabilins in elimination of oxidized low-density lipoproteins. Am J Physiol Gastrointest Liver Physiol (2011) 300(1):G71-81. doi:10.1152/ajpgi.00215.2010
    • (2011) Am J Physiol Gastrointest Liver Physiol , vol.300 , Issue.1 , pp. G71-81
    • Li, R.1    Oteiza, A.2    Sorensen, K.K.3    McCourt, P.4    Olsen, R.5    Smedsrod, B.6
  • 25
    • 0022496889 scopus 로고
    • Liver sinusoidal lining cells express class II major histocompatibility antigens but are poor stimulators of fresh allogenic T lymphocytes
    • Rubinstein D, Roska AK, Lipsky PE. Liver sinusoidal lining cells express class II major histocompatibility antigens but are poor stimulators of fresh allogenic T lymphocytes. J Immunol (1986) 137:1803-10.
    • (1986) J Immunol , vol.137 , pp. 1803-1810
    • Rubinstein, D.1    Roska, A.K.2    Lipsky, P.E.3
  • 26
    • 0029978748 scopus 로고    scopus 로고
    • Antigen-presenting function and B7 expression of murine sinusoidal endothelial cells and Kupffer cells
    • Lohse AW, Knolle PA, Bilo K, Uhrig A, Waldmann C, Ibe M, et al. Antigen-presenting function and B7 expression of murine sinusoidal endothelial cells and Kupffer cells. Gastroenterology (1996) 110:1175-81. doi:10.1053/gast.1996.v110.pm8613007
    • (1996) Gastroenterology , vol.110 , pp. 1175-1181
    • Lohse, A.W.1    Knolle, P.A.2    Bilo, K.3    Uhrig, A.4    Waldmann, C.5    Ibe, M.6
  • 27
    • 73149098744 scopus 로고    scopus 로고
    • Priming of CD4+ T cells by liver sinusoidal endothelial cells induces CD25low forkhead box protein 3-regulatory T cells suppressing autoimmune hepatitis
    • Kruse N, Neumann K, Schrage A, Derkow K, Schott E, Erben U, et al. Priming of CD4+ T cells by liver sinusoidal endothelial cells induces CD25low forkhead box protein 3-regulatory T cells suppressing autoimmune hepatitis. Hepatology (2009) 50(6):1904-13. doi:10.1002/hep.23191
    • (2009) Hepatology , vol.50 , Issue.6 , pp. 1904-1913
    • Kruse, N.1    Neumann, K.2    Schrage, A.3    Derkow, K.4    Schott, E.5    Erben, U.6
  • 28
    • 84929606125 scopus 로고    scopus 로고
    • Nanoparticle-based autoantigen delivery to Treg-inducing liver sinusoidal endothelial cells enables control of autoimmunity in mice
    • Carambia A, Freund B, Schwinge D, Bruns OT, Salmen SC, Ittrich H, et al. Nanoparticle-based autoantigen delivery to Treg-inducing liver sinusoidal endothelial cells enables control of autoimmunity in mice. J Hepatol (2015) 62(6):1349-56. doi:10.1016/j.jhep.2015.01.006
    • (2015) J Hepatol , vol.62 , Issue.6 , pp. 1349-1356
    • Carambia, A.1    Freund, B.2    Schwinge, D.3    Bruns, O.T.4    Salmen, S.C.5    Ittrich, H.6
  • 29
    • 0034533209 scopus 로고    scopus 로고
    • Efficient presentation of exogenous antigen by liver endothelial cells to CD8+ T-cells results in antigen specific T-cell tolerance
    • Limmer A, Ohl J, Kurts C, Ljunggren H-G, Reiss Y, Groettrup M, et al. Efficient presentation of exogenous antigen by liver endothelial cells to CD8+ T-cells results in antigen specific T-cell tolerance. Nat Med (2000) 6(12):1348-54. doi:10.1038/82161
    • (2000) Nat Med , vol.6 , Issue.12 , pp. 1348-1354
    • Limmer, A.1    Ohl, J.2    Kurts, C.3    Ljunggren, H.-G.4    Reiss, Y.5    Groettrup, M.6
  • 30
    • 70349229377 scopus 로고    scopus 로고
    • Distinct kinetics and dynamics of cross-presentation in liver sinusoidal endothelial cells compared to dendritic cells
    • Schurich A, Bottcher JP, Burgdorf S, Penzler P, Hegenbarth S, Kern M, et al. Distinct kinetics and dynamics of cross-presentation in liver sinusoidal endothelial cells compared to dendritic cells. Hepatology (2009) 50(3):909-19. doi:10.1002/hep.23075
    • (2009) Hepatology , vol.50 , Issue.3 , pp. 909-919
    • Schurich, A.1    Bottcher, J.P.2    Burgdorf, S.3    Penzler, P.4    Hegenbarth, S.5    Kern, M.6
  • 31
    • 84866954276 scopus 로고    scopus 로고
    • TNF-induced target cell killing by CTL activated through cross-presentation
    • Wohlleber D, Kashkar H, Gartner K, Frings MK, Odenthal M, Hegenbarth S, et al. TNF-induced target cell killing by CTL activated through cross-presentation. Cell Rep (2012) 2(3):478-87. doi:10.1016/j.celrep.2012.08.001
    • (2012) Cell Rep , vol.2 , Issue.3 , pp. 478-487
    • Wohlleber, D.1    Kashkar, H.2    Gartner, K.3    Frings, M.K.4    Odenthal, M.5    Hegenbarth, S.6
  • 32
    • 33751228135 scopus 로고    scopus 로고
    • Cross-presentation of antigens from apoptotic tumor cells by liver sinusoidal endothelial cells leads to tumor-specific CD8+ T cell tolerance
    • Berg M, Wingender G, Djandji D, Hegenbarth S, Momburg F, Hammerling G, et al. Cross-presentation of antigens from apoptotic tumor cells by liver sinusoidal endothelial cells leads to tumor-specific CD8+ T cell tolerance. Eur J Immunol (2006) 36(11):2960-70. doi:10.1002/eji.200636033
    • (2006) Eur J Immunol , vol.36 , Issue.11 , pp. 2960-2970
    • Berg, M.1    Wingender, G.2    Djandji, D.3    Hegenbarth, S.4    Momburg, F.5    Hammerling, G.6
  • 33
    • 38649137987 scopus 로고    scopus 로고
    • Tolerogenic maturation of liver sinusoidal endothelial cells promotes B7-homolog 1-dependent CD8+ T cell tolerance
    • Diehl L, Schurich A, Grochtmann R, Hegenbarth S, Chen L, Knolle PA. Tolerogenic maturation of liver sinusoidal endothelial cells promotes B7-homolog 1-dependent CD8+ T cell tolerance. Hepatology (2008) 47(1):296-305. doi:10.1002/hep.21965
    • (2008) Hepatology , vol.47 , Issue.1 , pp. 296-305
    • Diehl, L.1    Schurich, A.2    Grochtmann, R.3    Hegenbarth, S.4    Chen, L.5    Knolle, P.A.6
  • 34
    • 84922534448 scopus 로고    scopus 로고
    • IL-6 trans-signaling-dependent rapid development of cytotoxic CD8+ T cell function
    • Böttcher JP, Schanz O, Garbers C, Zaremba A, Hegenbarth S, Kurts C, et al. IL-6 trans-signaling-dependent rapid development of cytotoxic CD8+ T cell function. Cell Rep (2014) 8(5):1318-27. doi:10.1016/j.celrep.2014.07.008
    • (2014) Cell Rep , vol.8 , Issue.5 , pp. 1318-1327
    • Böttcher, J.P.1    Schanz, O.2    Garbers, C.3    Zaremba, A.4    Hegenbarth, S.5    Kurts, C.6
  • 35
    • 85010402409 scopus 로고    scopus 로고
    • Liver sinusoidal endothelial cell cross-priming is supported by CD4 T cell-derived IL-2
    • Wittlich M, Dudek M, Bottcher JP, Schanz O, Hegenbarth S, Bopp T, et al. Liver sinusoidal endothelial cell cross-priming is supported by CD4 T cell-derived IL-2. J Hepatol (2017) 66(5):978-86. doi:10.1016/j.jhep.2016.12.015
    • (2017) J Hepatol , vol.66 , Issue.5 , pp. 978-986
    • Wittlich, M.1    Dudek, M.2    Bottcher, J.P.3    Schanz, O.4    Hegenbarth, S.5    Bopp, T.6
  • 36
    • 84875809649 scopus 로고    scopus 로고
    • Liver-primed memory T cells generated under noninflammatory conditions provide anti-infectious immunity
    • Böttcher JP, Schanz O, Wohlleber D, Abdullah Z, Debey-Pascher S, Staratschek-Jox A, et al. Liver-primed memory T cells generated under noninflammatory conditions provide anti-infectious immunity. Cell Rep (2013) 3(3):779-95. doi:10.1016/j.celrep.2013.02.008
    • (2013) Cell Rep , vol.3 , Issue.3 , pp. 779-795
    • Böttcher, J.P.1    Schanz, O.2    Wohlleber, D.3    Abdullah, Z.4    Debey-Pascher, S.5    Staratschek-Jox, A.6
  • 37
    • 77951573803 scopus 로고    scopus 로고
    • Dynamic regulation of CD8 T cell tolerance induction by liver sinusoidal endothelial cells
    • Schurich A, Berg M, Stabenow D, Bottcher J, Kern M, Schild HJ, et al. Dynamic regulation of CD8 T cell tolerance induction by liver sinusoidal endothelial cells. J Immunol (2010) 184(8):4107-14. doi:10.4049/jimmunol.0902580
    • (2010) J Immunol , vol.184 , Issue.8 , pp. 4107-4114
    • Schurich, A.1    Berg, M.2    Stabenow, D.3    Bottcher, J.4    Kern, M.5    Schild, H.J.6
  • 38
    • 84965083364 scopus 로고    scopus 로고
    • T-cell exhaustion in chronic hepatitis B infection: current knowledge and clinical significance
    • Ye B, Liu X, Li X, Kong H, Tian L, Chen Y. T-cell exhaustion in chronic hepatitis B infection: current knowledge and clinical significance. Cell Death Dis (2015) 6:e1694. doi:10.1038/cddis.2015.42
    • (2015) Cell Death Dis , vol.6
    • Ye, B.1    Liu, X.2    Li, X.3    Kong, H.4    Tian, L.5    Chen, Y.6
  • 39
    • 84906319883 scopus 로고    scopus 로고
    • Transfer of MHC-class-I molecules among liver sinusoidal cells facilitates hepatic immune surveillance
    • Schölzel K, Schildberg FA, Welz M, Borner C, Geiger S, Kurts C, et al. Transfer of MHC-class-I molecules among liver sinusoidal cells facilitates hepatic immune surveillance. J Hepatol (2014) 61(3):600-8. doi:10.1016/j.jhep.2014.04.028
    • (2014) J Hepatol , vol.61 , Issue.3 , pp. 600-608
    • Schölzel, K.1    Schildberg, F.A.2    Welz, M.3    Borner, C.4    Geiger, S.5    Kurts, C.6
  • 40
    • 70349432265 scopus 로고    scopus 로고
    • Liver sinusoidal endothelial cell lectin, LSECtin, negatively regulates hepatic T-cell immune response
    • Tang L, Yang J, Liu W, Tang X, Chen J, Zhao D, et al. Liver sinusoidal endothelial cell lectin, LSECtin, negatively regulates hepatic T-cell immune response. Gastroenterology (2009) 137(4):.e1-5. doi:10.1053/j.gastro.2009.07.051
    • (2009) Gastroenterology , vol.137 , Issue.4
    • Tang, L.1    Yang, J.2    Liu, W.3    Tang, X.4    Chen, J.5    Zhao, D.6
  • 41
    • 77951088538 scopus 로고    scopus 로고
    • The DC-SIGN family member LSECtin is a novel ligand of CD44 on activated T cells
    • Tang L, Yang J, Tang X, Ying W, Qian X, He F. The DC-SIGN family member LSECtin is a novel ligand of CD44 on activated T cells. Eur J Immunol (2010) 40(4):1185-91. doi:10.1002/eji.200939936
    • (2010) Eur J Immunol , vol.40 , Issue.4 , pp. 1185-1191
    • Tang, L.1    Yang, J.2    Tang, X.3    Ying, W.4    Qian, X.5    He, F.6
  • 42
    • 18244364834 scopus 로고    scopus 로고
    • Development and functional consequences of LPS tolerance in sinusoidal endothelial cells of the liver
    • Uhrig A, Banafsche R, Kremer M, Hegenbarth S, Hamann A, Neurath M, et al. Development and functional consequences of LPS tolerance in sinusoidal endothelial cells of the liver. J Leukoc Biol (2005) 77(5):626-33. doi:10.1189/jlb.0604332
    • (2005) J Leukoc Biol , vol.77 , Issue.5 , pp. 626-633
    • Uhrig, A.1    Banafsche, R.2    Kremer, M.3    Hegenbarth, S.4    Hamann, A.5    Neurath, M.6
  • 43
    • 33751009401 scopus 로고    scopus 로고
    • T lymphocytes interact with hepatocytes through fenestrations in murine liver sinusoidal endothelial cells
    • Warren A, Le Couteur DG, Fraser R, Bowen DG, McCaughan GW, Bertolino P. T lymphocytes interact with hepatocytes through fenestrations in murine liver sinusoidal endothelial cells. Hepatology (2006) 44(5):1182-90. doi:10.1002/hep.21378
    • (2006) Hepatology , vol.44 , Issue.5 , pp. 1182-1190
    • Warren, A.1    Le Couteur, D.G.2    Fraser, R.3    Bowen, D.G.4    McCaughan, G.W.5    Bertolino, P.6
  • 44
    • 33845735525 scopus 로고    scopus 로고
    • Marked changes of the hepatic sinusoid in a transgenic mouse model of acute immune-mediated hepatitis
    • Warren A, Bertolino P, Benseler V, Fraser R, McCaughan GW, Le Couteur DG. Marked changes of the hepatic sinusoid in a transgenic mouse model of acute immune-mediated hepatitis. J Hepatol (2007) 46(2):239-46. doi:10.1016/j.jhep.2006.08.022
    • (2007) J Hepatol , vol.46 , Issue.2 , pp. 239-246
    • Warren, A.1    Bertolino, P.2    Benseler, V.3    Fraser, R.4    McCaughan, G.W.5    Le Couteur, D.G.6
  • 45
    • 2642674430 scopus 로고    scopus 로고
    • Hepatocytes induce functional activation of naive CD8+ T lymphocytes but fail to promote survival
    • Bertolino P, Trescol-Biémont M-C, Rabourdin-Combe C. Hepatocytes induce functional activation of naive CD8+ T lymphocytes but fail to promote survival. Eur J Immunol (1998) 28:221-36. doi:10.1002/(SICI)1521-4141(199801)28:01<221::AID-IMMU221>3.0.CO;2-F
    • (1998) Eur J Immunol , vol.28 , pp. 221-236
    • Bertolino, P.1    Trescol-Biémont, M.-C.2    Rabourdin-Combe, C.3
  • 46
    • 51449107778 scopus 로고    scopus 로고
    • Intrahepatic murine CD8 T-cell activation associates with a distinct phenotype leading to Bim-dependent death
    • Holz LE, Benseler V, Bowen DG, Bouillet P, Strasser A, O'Reilly L, et al. Intrahepatic murine CD8 T-cell activation associates with a distinct phenotype leading to Bim-dependent death. Gastroenterology (2008) 135(3):989-97. doi:10.1053/j.gastro.2008.05.078
    • (2008) Gastroenterology , vol.135 , Issue.3 , pp. 989-997
    • Holz, L.E.1    Benseler, V.2    Bowen, D.G.3    Bouillet, P.4    Strasser, A.5    O'Reilly, L.6
  • 47
    • 85014679740 scopus 로고    scopus 로고
    • Cross-presentation of soluble and cell-associated antigen by murine hepatocytes is enhanced by collectrin expression
    • Dolina JS, Cechova S, Rudy CK, Sung SJ, Tang WW, Lee J, et al. Cross-presentation of soluble and cell-associated antigen by murine hepatocytes is enhanced by collectrin expression. J Immunol (2017) 198(6):2341-51. doi:10.4049/jimmunol.1502234
    • (2017) J Immunol , vol.198 , Issue.6 , pp. 2341-2351
    • Dolina, J.S.1    Cechova, S.2    Rudy, C.K.3    Sung, S.J.4    Tang, W.W.5    Lee, J.6
  • 48
    • 84994582567 scopus 로고    scopus 로고
    • Effective intrahepatic CD8+ T-cell immune responses are induced by low but not high numbers of antigen-expressing hepatocytes
    • Ochel A, Cebula M, Riehn M, Hillebrand U, Lipps C, Schirmbeck R, et al. Effective intrahepatic CD8+ T-cell immune responses are induced by low but not high numbers of antigen-expressing hepatocytes. Cell Mol Immunol (2016) 13(6):805-15. doi:10.1038/cmi.2015.80
    • (2016) Cell Mol Immunol , vol.13 , Issue.6 , pp. 805-815
    • Ochel, A.1    Cebula, M.2    Riehn, M.3    Hillebrand, U.4    Lipps, C.5    Schirmbeck, R.6
  • 49
    • 84903456590 scopus 로고    scopus 로고
    • Antigen expression level threshold tunes the fate of CD8 T cells during primary hepatic immune responses
    • Tay SS, Wong YC, McDonald DM, Wood NAW, Roedinger B, Sierro F, et al. Antigen expression level threshold tunes the fate of CD8 T cells during primary hepatic immune responses. Proc Natl Acad Sci U S A (2014) 111(25):E2540-9. doi:10.1073/pnas.1406674111
    • (2014) Proc Natl Acad Sci U S A , vol.111 , Issue.25 , pp. E2540-E2549
    • Tay, S.S.1    Wong, Y.C.2    McDonald, D.M.3    Wood, N.A.W.4    Roedinger, B.5    Sierro, F.6
  • 50
    • 0037698820 scopus 로고    scopus 로고
    • MHC class II-expressing hepatocytes function as antigen-presenting cells and activate specific CD4 T lymphocytes
    • Herkel J, Jagemann B, Wiegard C, Lazaro JF, Lueth S, Kanzler S, et al. MHC class II-expressing hepatocytes function as antigen-presenting cells and activate specific CD4 T lymphocytes. Hepatology (2003) 37(5):1079-85. doi:10.1053/jhep.2003.50191
    • (2003) Hepatology , vol.37 , Issue.5 , pp. 1079-1085
    • Herkel, J.1    Jagemann, B.2    Wiegard, C.3    Lazaro, J.F.4    Lueth, S.5    Kanzler, S.6
  • 51
    • 55849093638 scopus 로고    scopus 로고
    • Ectopic expression of neural autoantigen in mouse liver suppresses experimental autoimmune neuroinflammation by inducing antigen-specific Tregs
    • Luth S, Huber S, Schramm C, Buch T, Zander S, Stadelmann C, et al. Ectopic expression of neural autoantigen in mouse liver suppresses experimental autoimmune neuroinflammation by inducing antigen-specific Tregs. J Clin Invest (2008) 118(10):3403-10. doi:10.1172/JCI32132
    • (2008) J Clin Invest , vol.118 , Issue.10 , pp. 3403-3410
    • Luth, S.1    Huber, S.2    Schramm, C.3    Buch, T.4    Zander, S.5    Stadelmann, C.6
  • 52
    • 36348973003 scopus 로고    scopus 로고
    • Differential priming of CD8 and CD4 T-cells in animal models of autoimmune hepatitis and cholangitis
    • Derkow K, Loddenkemper C, Mintern J, Kruse N, Klugewitz K, Berg T, et al. Differential priming of CD8 and CD4 T-cells in animal models of autoimmune hepatitis and cholangitis. Hepatology (2007) 46(4):1155-65. doi:10.1002/hep.21796
    • (2007) Hepatology , vol.46 , Issue.4 , pp. 1155-1165
    • Derkow, K.1    Loddenkemper, C.2    Mintern, J.3    Kruse, N.4    Klugewitz, K.5    Berg, T.6
  • 53
    • 79960290721 scopus 로고    scopus 로고
    • Failure of CD4 T-cells to respond to liver-derived antigen and to provide help to CD8 T-cells
    • Derkow K, Müller A, Eickmeier I, Seidel D, Rust Moreira MV, Kruse N, et al. Failure of CD4 T-cells to respond to liver-derived antigen and to provide help to CD8 T-cells. PLoS One (2011) 6(7):e21847. doi:10.1371/journal.pone.0021847
    • (2011) PLoS One , vol.6 , Issue.7
    • Derkow, K.1    Müller, A.2    Eickmeier, I.3    Seidel, D.4    Rust Moreira, M.V.5    Kruse, N.6
  • 54
    • 18244431128 scopus 로고    scopus 로고
    • Human hepatic stellate cells show features of antigen-presenting cells and stimulate lymphocyte proliferation
    • Vinas O, Bataller R, Sancho-Bru P, Ginès P, Berenguer C, Enrich C, et al. Human hepatic stellate cells show features of antigen-presenting cells and stimulate lymphocyte proliferation. Hepatology (2003) 38:919-29. doi:10.1002/hep.1840380418
    • (2003) Hepatology , vol.38 , pp. 919-929
    • Vinas, O.1    Bataller, R.2    Sancho-Bru, P.3    Ginès, P.4    Berenguer, C.5    Enrich, C.6
  • 55
    • 33846212347 scopus 로고    scopus 로고
    • Ito cells are liver-resident antigen-presenting cells for activating T cell responses
    • Winau F, Hegasy G, Weiskirchen R, Weber S, Cassan C, Sieling PA, et al. Ito cells are liver-resident antigen-presenting cells for activating T cell responses. Immunity (2007) 26(1):117-29. doi:10.1016/j.immuni.2006.11.011
    • (2007) Immunity , vol.26 , Issue.1 , pp. 117-129
    • Winau, F.1    Hegasy, G.2    Weiskirchen, R.3    Weber, S.4    Cassan, C.5    Sieling, P.A.6
  • 56
    • 58149355299 scopus 로고    scopus 로고
    • Hepatic stellate cells preferentially expand allogeneic CD4+ CD25+ FoxP3+ regulatory T cells in an IL-2-dependent manner
    • Jiang G, Yang HR, Wang L, Wildey GM, Fung J, Qian S, et al. Hepatic stellate cells preferentially expand allogeneic CD4+ CD25+ FoxP3+ regulatory T cells in an IL-2-dependent manner. Transplantation (2008) 86(11):1492-502. doi:10.1097/TP.0b013e31818bfd13
    • (2008) Transplantation , vol.86 , Issue.11 , pp. 1492-1502
    • Jiang, G.1    Yang, H.R.2    Wang, L.3    Wildey, G.M.4    Fung, J.5    Qian, S.6
  • 57
    • 77952742518 scopus 로고    scopus 로고
    • Analysis of antigen-presenting functionality of cultured rat hepatic stellate cells and transdifferentiated myofibroblasts
    • Bomble M, Tacke F, Rink L, Kovalenko E, Weiskirchen R. Analysis of antigen-presenting functionality of cultured rat hepatic stellate cells and transdifferentiated myofibroblasts. Biochem Biophys Res Commun (2010) 396(2):342-7. doi:10.1016/j.bbrc.2010.04.094
    • (2010) Biochem Biophys Res Commun , vol.396 , Issue.2 , pp. 342-347
    • Bomble, M.1    Tacke, F.2    Rink, L.3    Kovalenko, E.4    Weiskirchen, R.5
  • 58
    • 10644293881 scopus 로고    scopus 로고
    • Inhibition of T-cell responses by hepatic stellate cells via B7-H1-mediated T-cell apoptosis in mice
    • Yu MC, Chen CH, Liang X, Wang L, Gandhi CR, Fung JJ, et al. Inhibition of T-cell responses by hepatic stellate cells via B7-H1-mediated T-cell apoptosis in mice. Hepatology (2004) 40(6):1312-21. doi:10.1002/hep.20488
    • (2004) Hepatology , vol.40 , Issue.6 , pp. 1312-1321
    • Yu, M.C.1    Chen, C.H.2    Liang, X.3    Wang, L.4    Gandhi, C.R.5    Fung, J.J.6
  • 59
    • 78649566446 scopus 로고    scopus 로고
    • B7-H4 mediates inhibition of T cell responses by activated murine hepatic stellate cells
    • Chinnadurai R, Grakoui A. B7-H4 mediates inhibition of T cell responses by activated murine hepatic stellate cells. Hepatology (2010) 52(6):2177-85. doi:10.1002/hep.23953
    • (2010) Hepatology , vol.52 , Issue.6 , pp. 2177-2185
    • Chinnadurai, R.1    Grakoui, A.2
  • 60
    • 84879844767 scopus 로고    scopus 로고
    • Human hepatic stellate cells inhibit T-cell response through B7-H1 pathway
    • Charles R, Chou HS, Wang L, Fung JJ, Lu L, Qian S. Human hepatic stellate cells inhibit T-cell response through B7-H1 pathway. Transplantation (2013) 96(1):17-24. doi:10.1097/TP.0b013e318294caae
    • (2013) Transplantation , vol.96 , Issue.1 , pp. 17-24
    • Charles, R.1    Chou, H.S.2    Wang, L.3    Fung, J.J.4    Lu, L.5    Qian, S.6
  • 61
    • 84867298004 scopus 로고    scopus 로고
    • Hepatic stellate cells undermine the allostimulatory function of liver myeloid dendritic cells via STAT3-dependent induction of IDO
    • Sumpter TL, Dangi A, Matta BM, Huang C, Stolz DB, Vodovotz Y, et al. Hepatic stellate cells undermine the allostimulatory function of liver myeloid dendritic cells via STAT3-dependent induction of IDO. J Immunol (2012) 189(8):3848-58. doi:10.4049/jimmunol.1200819
    • (2012) J Immunol , vol.189 , Issue.8 , pp. 3848-3858
    • Sumpter, T.L.1    Dangi, A.2    Matta, B.M.3    Huang, C.4    Stolz, D.B.5    Vodovotz, Y.6
  • 62
    • 84882885600 scopus 로고    scopus 로고
    • Activated human hepatic stellate cells induce myeloid derived suppressor cells from peripheral blood monocytes in a CD44-dependent fashion
    • Höchst B, Schildberg FA, Sauerborn P, Gabel YA, Gevensleben H, Goltz D, et al. Activated human hepatic stellate cells induce myeloid derived suppressor cells from peripheral blood monocytes in a CD44-dependent fashion. J Hepatol (2013) 59(3):528-35. doi:10.1016/j.jhep.2013.04.033
    • (2013) J Hepatol , vol.59 , Issue.3 , pp. 528-535
    • Höchst, B.1    Schildberg, F.A.2    Sauerborn, P.3    Gabel, Y.A.4    Gevensleben, H.5    Goltz, D.6
  • 63
    • 84874268340 scopus 로고    scopus 로고
    • Hepatic stellate cells preferentially induce Foxp3+ regulatory T cells by production of retinoic acid
    • Dunham RM, Thapa M, Velazquez VM, Elrod EJ, Denning TL, Pulendran B, et al. Hepatic stellate cells preferentially induce Foxp3+ regulatory T cells by production of retinoic acid. J Immunol (2013) 190(5):2009-16. doi:10.4049/jimmunol.1201937
    • (2013) J Immunol , vol.190 , Issue.5 , pp. 2009-2016
    • Dunham, R.M.1    Thapa, M.2    Velazquez, V.M.3    Elrod, E.J.4    Denning, T.L.5    Pulendran, B.6
  • 64
    • 79959555074 scopus 로고    scopus 로고
    • Murine hepatic stellate cells veto CD8 T cell activation by a CD54-dependent mechanism
    • Schildberg FA, Wojtalla A, Siegmund SV, Endl E, Diehl L, Abdullah Z, et al. Murine hepatic stellate cells veto CD8 T cell activation by a CD54-dependent mechanism. Hepatology (2011) 54(1):262-72. doi:10.1002/hep.24352
    • (2011) Hepatology , vol.54 , Issue.1 , pp. 262-272
    • Schildberg, F.A.1    Wojtalla, A.2    Siegmund, S.V.3    Endl, E.4    Diehl, L.5    Abdullah, Z.6
  • 65
    • 0028999713 scopus 로고
    • Immunogenicity of biliary epithelial cells: study of the expression of B7 molecules
    • Leon MP, Kirby JA, Gibbs P, Burt AD, Bassendine MF. Immunogenicity of biliary epithelial cells: study of the expression of B7 molecules. J Hepatol (1995) 22:591-5. doi:10.1016/0168-8278(95)80456-0
    • (1995) J Hepatol , vol.22 , pp. 591-595
    • Leon, M.P.1    Kirby, J.A.2    Gibbs, P.3    Burt, A.D.4    Bassendine, M.F.5
  • 66
    • 0029844861 scopus 로고    scopus 로고
    • Immunogenecity of biliary epithelium: investigation of antigen presentation to CD4+ T cells
    • Leon MP, Bassendine MF, Wilson JL, Simi A, Thick M, Kirby JA. Immunogenecity of biliary epithelium: investigation of antigen presentation to CD4+ T cells. Hepatology (1996) 24:561-7. doi:10.1002/hep.510240317
    • (1996) Hepatology , vol.24 , pp. 561-567
    • Leon, M.P.1    Bassendine, M.F.2    Wilson, J.L.3    Simi, A.4    Thick, M.5    Kirby, J.A.6
  • 67
    • 0027254763 scopus 로고
    • Intercellular adhesion molecule-1 and MHC antigens on human intrahepatic bile duct cells: effect of pro-inflammatory cytokines
    • Ayres RC, Neuberger JM, Shaw J, Joplin R, Adams DH. Intercellular adhesion molecule-1 and MHC antigens on human intrahepatic bile duct cells: effect of pro-inflammatory cytokines. Gut (1993) 34(9):1245-9. doi:10.1136/gut.34.9.1245
    • (1993) Gut , vol.34 , Issue.9 , pp. 1245-1249
    • Ayres, R.C.1    Neuberger, J.M.2    Shaw, J.3    Joplin, R.4    Adams, D.H.5
  • 68
    • 84975726320 scopus 로고    scopus 로고
    • Biliary epithelium and liver B cells exposed to bacteria activate intrahepatic MAIT cells through MR1
    • Jeffery HC, van Wilgenburg B, Kurioka A, Parekh K, Stirling K, Roberts S, et al. Biliary epithelium and liver B cells exposed to bacteria activate intrahepatic MAIT cells through MR1. J Hepatol (2016) 64(5):1118-27. doi:10.1016/j.jhep.2015.12.017
    • (2016) J Hepatol , vol.64 , Issue.5 , pp. 1118-1127
    • Jeffery, H.C.1    van Wilgenburg, B.2    Kurioka, A.3    Parekh, K.4    Stirling, K.5    Roberts, S.6
  • 69
    • 77954914800 scopus 로고    scopus 로고
    • Antimicrobial activity of mucosal-associated invariant T cells
    • Le Bourhis L, Martin E, Peguillet I, Guihot A, Froux N, Core M, et al. Antimicrobial activity of mucosal-associated invariant T cells. Nat Immunol (2010) 11(8):701-8. doi:10.1038/ni.1890
    • (2010) Nat Immunol , vol.11 , Issue.8 , pp. 701-708
    • Le Bourhis, L.1    Martin, E.2    Peguillet, I.3    Guihot, A.4    Froux, N.5    Core, M.6
  • 70
    • 84870284140 scopus 로고    scopus 로고
    • MR1 presents microbial vitamin B metabolites to MAIT cells
    • Kjer-Nielsen L, Patel O, Corbett AJ, Le Nours J, Meehan B, Liu L, et al. MR1 presents microbial vitamin B metabolites to MAIT cells. Nature (2012) 491(7426):717-23. doi:10.1038/nature11605
    • (2012) Nature , vol.491 , Issue.7426 , pp. 717-723
    • Kjer-Nielsen, L.1    Patel, O.2    Corbett, A.J.3    Le Nours, J.4    Meehan, B.5    Liu, L.6
  • 72
    • 80054918372 scopus 로고    scopus 로고
    • Regulated release of nitric oxide by nonhematopoietic stroma controls expansion of the activated T cell pool in lymph nodes
    • Lukacs-Kornek V, Malhotra D, Fletcher AL, Acton SE, Elpek KG, Tayalia P, et al. Regulated release of nitric oxide by nonhematopoietic stroma controls expansion of the activated T cell pool in lymph nodes. Nat Immunol (2011) 12(11):1096-104. doi:10.1038/ni.2112
    • (2011) Nat Immunol , vol.12 , Issue.11 , pp. 1096-1104
    • Lukacs-Kornek, V.1    Malhotra, D.2    Fletcher, A.L.3    Acton, S.E.4    Elpek, K.G.5    Tayalia, P.6
  • 73
    • 84901247776 scopus 로고    scopus 로고
    • Steady-state antigen scavenging, cross-presentation, and CD8+ T cell priming: a new role for lymphatic endothelial cells
    • Hirosue S, Vokali E, Raghavan VR, Rincon-Restrepo M, Lund AW, Corthesy-Henrioud P, et al. Steady-state antigen scavenging, cross-presentation, and CD8+ T cell priming: a new role for lymphatic endothelial cells. J Immunol (2014) 192(11):5002-11. doi:10.4049/jimmunol.1302492
    • (2014) J Immunol , vol.192 , Issue.11 , pp. 5002-5011
    • Hirosue, S.1    Vokali, E.2    Raghavan, V.R.3    Rincon-Restrepo, M.4    Lund, A.W.5    Corthesy-Henrioud, P.6
  • 74
    • 77951069509 scopus 로고    scopus 로고
    • Lymph node-resident lymphatic endothelial cells mediate peripheral tolerance via Aire-independent direct antigen presentation
    • Cohen JN, Guidi CJ, Tewalt EF, Qiao H, Rouhani SJ, Ruddell A, et al. Lymph node-resident lymphatic endothelial cells mediate peripheral tolerance via Aire-independent direct antigen presentation. J Exp Med (2010) 207(4):681-8. doi:10.1084/jem.20092465
    • (2010) J Exp Med , vol.207 , Issue.4 , pp. 681-688
    • Cohen, J.N.1    Guidi, C.J.2    Tewalt, E.F.3    Qiao, H.4    Rouhani, S.J.5    Ruddell, A.6
  • 75
    • 77951074210 scopus 로고    scopus 로고
    • Lymph node fibroblastic reticular cells directly present peripheral tissue antigen under steady-state and inflammatory conditions
    • Fletcher AL, Lukacs-Kornek V, Reynoso ED, Pinner SE, Bellemare-Pelletier A, Curry MS, et al. Lymph node fibroblastic reticular cells directly present peripheral tissue antigen under steady-state and inflammatory conditions. J Exp Med (2010) 207(4):689-97. doi:10.1084/jem.20092642
    • (2010) J Exp Med , vol.207 , Issue.4 , pp. 689-697
    • Fletcher, A.L.1    Lukacs-Kornek, V.2    Reynoso, E.D.3    Pinner, S.E.4    Bellemare-Pelletier, A.5    Curry, M.S.6
  • 76
    • 68149124237 scopus 로고    scopus 로고
    • Inflamed lymphatic endothelium suppresses dendritic cell maturation and function via Mac-1/ICAM-1-dependent mechanism
    • Podgrabinska S, Kamalu O, Mayer L, Shimaoka M, Snoeck H, Randolph GJ, et al. Inflamed lymphatic endothelium suppresses dendritic cell maturation and function via Mac-1/ICAM-1-dependent mechanism. J Immunol (2009) 183(3):1767-79. doi:10.4049/jimmunol.0802167
    • (2009) J Immunol , vol.183 , Issue.3 , pp. 1767-1779
    • Podgrabinska, S.1    Kamalu, O.2    Mayer, L.3    Shimaoka, M.4    Snoeck, H.5    Randolph, G.J.6
  • 79
    • 84988372460 scopus 로고    scopus 로고
    • Inhibition of mast cell-secreted histamine decreases biliary proliferation and fibrosis in primary sclerosing cholangitis MDR2-/- mice
    • Jones H, Hargrove L, Kennedy L, Meng F, Graf-Eaton A, Owens J, et al. Inhibition of mast cell-secreted histamine decreases biliary proliferation and fibrosis in primary sclerosing cholangitis MDR2-/- mice. Hepatology (2016) 64(4):1202-16. doi:10.1002/hep.28704/suppinfo
    • (2016) Hepatology , vol.64 , Issue.4 , pp. 1202-1216
    • Jones, H.1    Hargrove, L.2    Kennedy, L.3    Meng, F.4    Graf-Eaton, A.5    Owens, J.6
  • 80
    • 85018938765 scopus 로고    scopus 로고
    • Bile duct ligation-induced biliary hyperplasia, hepatic injury, and fibrosis are reduced in mast cell-deficient kit(W-sh) mice
    • Hargrove L, Kennedy L, Demieville J, Jones H, Meng F, DeMorrow S, et al. Bile duct ligation-induced biliary hyperplasia, hepatic injury, and fibrosis are reduced in mast cell-deficient kit(W-sh) mice. Hepatology (2017) 65(6):1991-2004. doi:10.1002/hep.29079/suppinfo
    • (2017) Hepatology , vol.65 , Issue.6 , pp. 1991-2004
    • Hargrove, L.1    Kennedy, L.2    Demieville, J.3    Jones, H.4    Meng, F.5    DeMorrow, S.6
  • 81
    • 84876480019 scopus 로고    scopus 로고
    • Emergence, origin, and function of neutrophil-dendritic cell hybrids in experimentally induced inflammatory lesions in mice
    • Geng S, Matsushima H, Okamoto T, Yao Y, Lu RS, Page K, et al. Emergence, origin, and function of neutrophil-dendritic cell hybrids in experimentally induced inflammatory lesions in mice. Blood (2013) 121(10):1690-700. doi:10.1182/blood-2012-07445197
    • (2013) Blood , vol.121 , Issue.10 , pp. 1690-1700
    • Geng, S.1    Matsushima, H.2    Okamoto, T.3    Yao, Y.4    Lu, R.S.5    Page, K.6
  • 82
    • 85018890975 scopus 로고    scopus 로고
    • Neutrophils acquire the capacity for antigen presentation to memory CD4+ T cells in vitro and ex vivo
    • Vono M, Lin A, Norrby-Teglund A, Koup RA, Liang F, Loré K. Neutrophils acquire the capacity for antigen presentation to memory CD4+ T cells in vitro and ex vivo. Blood (2017) 129(14):1991-2001. doi:10.1182/blood-2016-10744441
    • (2017) Blood , vol.129 , Issue.14 , pp. 1991-2001
    • Vono, M.1    Lin, A.2    Norrby-Teglund, A.3    Koup, R.A.4    Liang, F.5    Loré, K.6
  • 83
    • 2542448243 scopus 로고    scopus 로고
    • CD1: antigen presentation and T cell function
    • Brigl M, Brenner MB. CD1: antigen presentation and T cell function. Annu Rev Immunol (2004) 22:817-90. doi:10.1146/annurev.immunol.22.012703.104608
    • (2004) Annu Rev Immunol , vol.22 , pp. 817-890
    • Brigl, M.1    Brenner, M.B.2
  • 84
    • 84857684717 scopus 로고    scopus 로고
    • Novel insights into lipid antigen presentation
    • De Libero G, Mori L. Novel insights into lipid antigen presentation. Trends Immunol (2012) 33(3):103-11. doi:10.1016/j.it.2012.01.005
    • (2012) Trends Immunol , vol.33 , Issue.3 , pp. 103-111
    • De Libero, G.1    Mori, L.2
  • 85
    • 84969752983 scopus 로고    scopus 로고
    • The immunology of CD1- and MR1-restricted T cells
    • Mori L, Lepore M, De Libero G. The immunology of CD1- and MR1-restricted T cells. Annu Rev Immunol (2016) 34:479-510. doi:10.1146/annurev-immunol-032414-112008
    • (2016) Annu Rev Immunol , vol.34 , pp. 479-510
    • Mori, L.1    Lepore, M.2    De Libero, G.3
  • 86
    • 84942553335 scopus 로고    scopus 로고
    • The biliary epithelium presents antigens to and activates natural killer T cells
    • Schrumpf E, Tan C, Karlsen TH, Sponheim J, Björkström NK, Sundens O, et al. The biliary epithelium presents antigens to and activates natural killer T cells. Hepatology (2015) 62:1249-59. doi:10.1002/hep.27840/suppinfo
    • (2015) Hepatology , vol.62 , pp. 1249-1259
    • Schrumpf, E.1    Tan, C.2    Karlsen, T.H.3    Sponheim, J.4    Björkström, N.K.5    Sundens, O.6
  • 87
    • 85029957499 scopus 로고    scopus 로고
    • CD1d-restricted pathways in hepatocytes control local natural killer T cell homeostasis and hepatic inflammation
    • Zeissig S, Peuker K, Iyer S, Gensollen T, Dougan SK, Olszak T, et al. CD1d-restricted pathways in hepatocytes control local natural killer T cell homeostasis and hepatic inflammation. Proc Natl Acad Sci U S A (2017) 114(39):10449-54. doi:10.1073/pnas.1701428114
    • (2017) Proc Natl Acad Sci U S A , vol.114 , Issue.39 , pp. 10449-10454
    • Zeissig, S.1    Peuker, K.2    Iyer, S.3    Gensollen, T.4    Dougan, S.K.5    Olszak, T.6
  • 89
    • 84863707404 scopus 로고    scopus 로고
    • Hepatitis B virus-induced lipid alterations contribute to natural killer T cell-dependent protective immunity
    • Zeissig S, Murata K, Sweet L, Publicover J, Hu Z, Kaser A, et al. Hepatitis B virus-induced lipid alterations contribute to natural killer T cell-dependent protective immunity. Nat Med (2012) 18(7):1060-8. doi:10.1038/nm.2811
    • (2012) Nat Med , vol.18 , Issue.7 , pp. 1060-1068
    • Zeissig, S.1    Murata, K.2    Sweet, L.3    Publicover, J.4    Hu, Z.5    Kaser, A.6
  • 90
    • 85016109928 scopus 로고    scopus 로고
    • Tailored design of NKT-stimulatory glycolipids for polarization of immune responses
    • Hung JT, Huang JR, Yu AL. Tailored design of NKT-stimulatory glycolipids for polarization of immune responses. J Biomed Sci (2017) 24(1):22. doi:10.1186/s12929-017-0325-0
    • (2017) J Biomed Sci , vol.24 , Issue.1 , pp. 22
    • Hung, J.T.1    Huang, J.R.2    Yu, A.L.3
  • 91
    • 0031751551 scopus 로고    scopus 로고
    • Increased CD1d expression on small bile duct epithelium and epithelioid granuloma in livers in primary biliary cirrhosis
    • Tsuneyama K, Yasoshima M, Harada K, Hiramatsu K, Gershwin ME, Nakanuma Y. Increased CD1d expression on small bile duct epithelium and epithelioid granuloma in livers in primary biliary cirrhosis. Hepatology (1998) 28:620-3. doi:10.1002/hep.510280303
    • (1998) Hepatology , vol.28 , pp. 620-623
    • Tsuneyama, K.1    Yasoshima, M.2    Harada, K.3    Hiramatsu, K.4    Gershwin, M.E.5    Nakanuma, Y.6
  • 92
    • 84878233150 scopus 로고    scopus 로고
    • Intrahepatic myeloid-cell aggregates enable local proliferation of CD8(+) T cells and successful immunotherapy against chronic viral liver infection
    • Huang LR, Wohlleber D, Reisinger F, Jenne CN, Cheng RL, Abdullah Z, et al. Intrahepatic myeloid-cell aggregates enable local proliferation of CD8(+) T cells and successful immunotherapy against chronic viral liver infection. Nat Immunol (2013) 14(6):574-83. doi:10.1038/ni.2573
    • (2013) Nat Immunol , vol.14 , Issue.6 , pp. 574-583
    • Huang, L.R.1    Wohlleber, D.2    Reisinger, F.3    Jenne, C.N.4    Cheng, R.L.5    Abdullah, Z.6


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