Intrahepatic myeloid-cell aggregates enable local proliferation of CD8 + T cells and successful immunotherapy against chronic viral liver infection

Nature Immunology

Volumn 14, Issue 6, 2013, Pages 574-583

  Huang, Li Rung ^a   Wohlleber, Dirk ^a   Reisinger, Florian ^b   Jenne, Craig N ^c   Cheng, Ru Lin ^a   Abdullah, Zeinab ^a   Schildberg, Frank A ^a   Odenthal, Margarete ^d   Dienes, Hans Peter ^d   Van Rooijen, Nico ^e   Schmitt, Edgar ^f   Garbi, Natalio ^a   Croft, Michael ^g   Kurts, Christian ^a   Kubes, Paul ^c   Protzer, Ulrike ^b   Heikenwalder, Mathias ^b   Knolle, Percy A ^a,b  

^a UNIVERSITY OF BONN   (Germany)

^b TECHNICAL UNIVERSITY OF MUNICH   (Germany)

^c UNIVERSITY OF CALGARY   (Canada)

^d UNIVERSITY OF COLOGNE   (Germany)

^e VU UNIVERSITY MEDICAL CENTER   (Netherlands)

^f JOHANNES GUTENBERG UNIVERSITY   (Germany)

^g LA JOLLA INSTITUTE FOR ALLERGY AND IMMUNOLOGY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

HEPATITIS B ANTIGEN; OX40 LIGAND; TOLL LIKE RECEPTOR; TUMOR NECROSIS FACTOR;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BONE MARROW CELL; CD8+ T LYMPHOCYTE; CELL AGGREGATION; CELL EXPANSION; CELL POPULATION; CELL PROLIFERATION; CELL STIMULATION; CHRONIC HEPATITIS; CONTROLLED STUDY; HEPATITIS B; IMMUNOPATHOLOGY; IMMUNOTHERAPY; MONOCYTE; MOUSE; NONHUMAN; PRIORITY JOURNAL; SIGNAL TRANSDUCTION; TREATMENT RESPONSE; VIRUS HEPATITIS;

ANIMALS; ANIMALS, NEWBORN; ANTIGENS, CD11B; CD8-POSITIVE T-LYMPHOCYTES; CELL PROLIFERATION; CHRONIC DISEASE; FLOW CYTOMETRY; GREEN FLUORESCENT PROTEINS; HOST-PATHOGEN INTERACTIONS; IMMUNOTHERAPY; LIVER; LIVER DISEASES; LYMPHOCYTIC CHORIOMENINGITIS; LYMPHOCYTIC CHORIOMENINGITIS VIRUS; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; MICE, TRANSGENIC; MICROSCOPY, CONFOCAL; MYELOID CELLS; RECEPTORS, OX40; SIGNAL TRANSDUCTION; T-LYMPHOCYTES, CYTOTOXIC; TOLL-LIKE RECEPTOR 9;

EID: 84878233150     PISSN: 15292908     EISSN: 15292916     Source Type: Journal    
DOI: 10.1038/ni.2573     Document Type: Article

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