Antigen expression level threshold tunes the fate of CD8 T cells during primary hepatic immune responses

Proceedings of the National Academy of Sciences of the United States of America

Volumn 111, Issue 25, 2014, Pages

  Tay, Szun Szun ^a   Wong, Yik Chun ^a   McDonald, David M ^a   Wood, Nicole A W ^a   Roediger, Ben ^a   Sierro, Frederic ^a   Mcguffog, Claire ^a   Alexander, Ian E ^b   Bishop, G Alex ^a   Gamble, Jennifer R ^c   Weninger, Wolfgang ^a,c   McCaughan, Geoffrey W ^a   Bertolino, Patrick ^a   Bowen, David G ^a  

^a ROYAL PRINCE ALFRED HOSPITAL   (Australia)

^b CHILDREN S HOSPITAL AT WESTMEAD   (Australia)

^c UNIVERSITY OF SYDNEY   (Australia)

Author keywords

CTL; Cytotoxicity; rAAV; TCR

Indexed keywords

ALANINE AMINOTRANSFERASE; MEMBRANE ANTIGEN; T LYMPHOCYTE RECEPTOR;

ADOPTIVE TRANSFER; ALANINE AMINOTRANSFERASE BLOOD LEVEL; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ANTIGEN EXPRESSION; ARTICLE; CD8+ T LYMPHOCYTE; CELL FATE; CELL SPECIFICITY; CELL STIMULATION; CONTROLLED STUDY; CROSS PRESENTATION; CYTOLYSIS; CYTOTOXICITY; CYTOTOXICITY ASSAY; EFFECTOR CELL; FLOW CYTOMETRY; IMMUNE RESPONSE; IN VIVO STUDY; LIVER; LIVER CELL; LYMPHOCYTE FUNCTION; LYMPHOID TISSUE; MOUSE; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; RECEPTOR AFFINITY; T LYMPHOCYTE ACTIVATION;

CTL; CYTOTOXICITY; RAAV; TCR;

ANIMALS; ANTIGENS; CD8-POSITIVE T-LYMPHOCYTES; GENE EXPRESSION REGULATION; HEPATOCYTES; LIVER; MICE; MICE, KNOCKOUT;

EID: 84903456590     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1406674111     Document Type: Article

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