GPR81, a cell-surface receptor for lactate, regulates intestinal homeostasis and protects mice from experimental colitis

Journal of Immunology

Volumn 200, Issue 5, 2018, Pages 1781-1789

  Ranganathan, Punithavathi ^a   Shanmugam, Arulkumaran ^a   Swafford, Daniel ^a   Suryawanshi, Amol ^a   Bhattacharjee, Pushpak ^b   Hussein, Mohamed S ^a   Koni, Pandelakis A ^a   Prasad, Puttur D ^a   Kurago, Zoya B ^c   Thangaraju, Muthusamy ^a   Ganapathy, Vadivel ^b   Manicassamy, Santhakumar ^a  

^a MEDICAL COLLEGE OF GEORGIA   (United States)

^b TEXAS TECH UNIVERSITY HEALTH SCIENCES CENTER SCHOOL OF MEDICINE   (United States)

^c AUGUSTA UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CELL SURFACE RECEPTOR; GPR81 PROTEIN; IDO PROTEIN; INTERLEUKIN 10; INTERLEUKIN 1BETA; INTERLEUKIN 6; LACTIC ACID; REGULATOR PROTEIN; RETINOIC ACID; TUMOR NECROSIS FACTOR; UNCLASSIFIED DRUG; CYTOKINE; G PROTEIN COUPLED RECEPTOR; G PROTEIN-COUPLED RECEPTOR 81, MOUSE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIGEN PRESENTING CELL; ARTICLE; COLITIS; COLON; CYTOKINE PRODUCTION; DENDRITIC CELL; DISEASE PREDISPOSITION; EXPERIMENTAL COLITIS; GENE DELETION; HOMEOSTASIS; IMMUNOLOGICAL TOLERANCE; INTESTINAL HOMEOSTASIS; INTESTINE; LYMPHOCYTE DIFFERENTIATION; MACROPHAGE; MOUSE; MULTICENTER STUDY; NONHUMAN; PRIORITY JOURNAL; PROTEIN FUNCTION; PROTEIN SECRETION; REGULATORY T LYMPHOCYTE; SIGNAL TRANSDUCTION; TH1 CELL; TH17 CELL; ANIMAL; C57BL MOUSE; DISEASE MODEL; FEMALE; MALE; METABOLISM; PHYSIOLOGY;

ANIMALS; COLITIS; CYTOKINES; DISEASE MODELS, ANIMAL; FEMALE; HOMEOSTASIS; LACTIC ACID; MACROPHAGES; MALE; MICE; MICE, INBRED C57BL; RECEPTORS, CELL SURFACE; RECEPTORS, G-PROTEIN-COUPLED; TH1 CELLS;

EID: 85044762873     PISSN: 00221767     EISSN: 15506606     Source Type: Journal    
DOI: 10.4049/jimmunol.1700604     Document Type: Article

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