Comparative pharmacokinetic study of paeoniflorin and albiflorin after oral administration of Radix Paeoniae Rubra in normal rats and the acute cholestasis hepatitis rats

Fitoterapia

Volumn 83, Issue 2, 2012, Pages 415-421

  Jiang, Fengjuan ^a,b   Zhao, Yanling ^a   Wang, Jiabo ^a   Wei, Sisi ^a,b   Wei, Zhenman ^a   Li, Ruisheng ^a   Zhu, Yun ^a   Sun, Zhiyong ^a,b   Xiao, Xiaohe ^c  

^a BEIJING 302 HOSPITAL   (China)

^b CHENGDU UNIVERSITY OF TRADITIONAL CHINESE MEDICINE   (China)

^c 302 MILITARY HOSPITAL   (China)

Author keywords

Acute cholestasis hepatitis; Albiflorin; Paeoniflorin; Pharmacokinetic; Radix Paeoniae Rubra; UPLC ESI MS MS

Indexed keywords

1 NAPHTHYL ISOTHIOCYANATE; ALBIFLORIN; GENIPOSIDE; PAEONIA RADIX; PAEONIFLORIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; AREA UNDER THE CURVE; ARTICLE; CHOLESTATIC HEPATITIS; COMPARATIVE STUDY; CONTROLLED STUDY; DISEASE ACTIVITY; DRUG ISOLATION; DRUG METABOLISM; ELECTROSPRAY MASS SPECTROMETRY; MALE; MAXIMUM PLASMA CONCENTRATION; NONHUMAN; PRIORITY JOURNAL; RAT; SENSITIVITY AND SPECIFICITY; TIME TO MAXIMUM PLASMA CONCENTRATION; ULTRA PERFORMANCE LIQUID CHROMATOGRAPHY;

ACUTE DISEASE; ADMINISTRATION, ORAL; ANIMALS; ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL; BENZOATES; BRIDGED COMPOUNDS; CHOLESTASIS; DRUGS, CHINESE HERBAL; GLUCOSIDES; HEPATITIS; HUMANS; MALE; PAEONIA; RANDOM ALLOCATION; RATS; RATS, SPRAGUE-DAWLEY; SENSITIVITY AND SPECIFICITY; TIME FACTORS;

RATTUS;

EID: 84855987226     PISSN: 0367326X     EISSN: 18736971     Source Type: Journal    
DOI: 10.1016/j.fitote.2011.12.009     Document Type: Article

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