PheWAS and Beyond: The Landscape of Associations with Medical Diagnoses and Clinical Measures across 38,662 Individuals from Geisinger

American Journal of Human Genetics

Volumn 102, Issue 4, 2018, Pages 592-608

  Verma, Anurag ^b,c   Lucas, Anastasia ^b   Verma, Shefali S ^b,c   Zhang, Yu ^d   Josyula, Navya ^a   Khan, Anqa ^e   Hartzel, Dustin N ^a   Lavage, Daniel R ^a   Leader, Joseph ^a   Ritchie, Marylyn D ^b,c,d   Pendergrass, Sarah A ^a  

^a GEISINGER HEALTH SYSTEM   (United States)

^b UNIVERSITY OF PENNSYLVANIA   (United States)

^c PENNSYLVANIA STATE UNIVERSITY   (United States)

^d PENNSYLVANIA STATE UNIVERSITY   (United States)

^e MOUNT HOLYOKE COLLEGE   (United States)

Author keywords

bioinformatics; biorepository; EHR; genetic epidemiology; genomics; GWAS; phenome wide; PheWAS

Indexed keywords

ARTICLE; CASE CONTROL STUDY; COHORT ANALYSIS; CONTROLLED STUDY; ELECTRONIC HEALTH RECORD; FEMALE; GENE FREQUENCY; GENETIC ASSOCIATION STUDY; GENETIC TRAIT; HUMAN; MALE; PHENOME WIDE ASSOCIATION STUDY; PHENOTYPE; SINGLE NUCLEOTIDE POLYMORPHISM; CHROMATIN; GENE EXPRESSION REGULATION; GENETICS; GENOME-WIDE ASSOCIATION STUDY; HAPLOTYPE; HUMAN GENOME; INTERNATIONAL CLASSIFICATION OF DISEASES; LABORATORY TECHNIQUE; MOLECULAR GENETICS; OPEN READING FRAME; REPRODUCIBILITY; SEQUENCE ANALYSIS;

SPACER DNA;

CHROMATIN; CLINICAL LABORATORY TECHNIQUES; DNA, INTERGENIC; ELECTRONIC HEALTH RECORDS; GENE EXPRESSION REGULATION; GENOME, HUMAN; GENOME-WIDE ASSOCIATION STUDY; HAPLOTYPES; HUMANS; INTERNATIONAL CLASSIFICATION OF DISEASES; MOLECULAR SEQUENCE ANNOTATION; OPEN READING FRAMES; PHENOTYPE; REPRODUCIBILITY OF RESULTS; SEQUENCE ANALYSIS, RNA;

EID: 85044160882     PISSN: 00029297     EISSN: 15376605     Source Type: Journal    
DOI: 10.1016/j.ajhg.2018.02.017     Document Type: Article

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