Deficiency of the stroke relevant HDAC9 gene attenuates atherosclerosis in accord with allele-specific effects at 7p21.1

Stroke

Volumn 46, Issue 1, 2015, Pages 197-202

  Azghandi, Sepiede ^a   Prell, Caroline ^a   Van Der Laan, Sander W ^b   Schneider, Manuela ^a   Malik, Rainer ^a   Berer, Kerstin ^c   Gerdes, Norbert ^a   Pasterkamp, Gerard ^b   Weber, Christian ^a   Haffner, Christof ^a   Dichgans, Martin ^a,d  

^a LUDWIG MAXIMILIANS UNIVERSITY   (Germany)

^b UNIVERSITY MEDICAL CENTER UTRECHT   (Netherlands)

^c MAX PLANCK INSTITUTE OF NEUROBIOLOGY   (Germany)

^d Technische Universität München Munich Cluster for Systems Neurology   (Germany)

Author keywords

atherosclerosis; HDAC9 protein, human; stroke

Indexed keywords

HISTONE DEACETYLASE 9; APOLIPOPROTEIN E; HDAC9 PROTEIN, HUMAN; HDAC9 PROTEIN, MOUSE; HISTONE DEACETYLASE; MESSENGER RNA; REPRESSOR PROTEIN;

ADULT; AGED; ALLELE; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BLOOD ANALYSIS; CAROTID ATHEROSCLEROSIS; CAROTID ENDARTERECTOMY; CELL STRUCTURE; CEREBROVASCULAR ACCIDENT; COMPARATIVE STUDY; CONTROLLED STUDY; FEMALE; GENE EXPRESSION; GENETIC ASSOCIATION; GENETIC RISK; GENETIC VARIABILITY; GENOTYPE; HISTOPATHOLOGY; HUMAN; IMMUNOHISTOCHEMISTRY; MACROPHAGE; MAJOR CLINICAL STUDY; MALE; MOUSE; NONHUMAN; PERIPHERAL BLOOD MONONUCLEAR CELL; PHENOTYPIC VARIATION; RISK ASSESSMENT; RISK FACTOR; SINGLE NUCLEOTIDE POLYMORPHISM; ANIMAL; ATHEROSCLEROTIC PLAQUE; CAROTID ARTERY DISEASE; GENE EXPRESSION PROFILING; GENETIC PREDISPOSITION; GENETICS; KNOCKOUT MOUSE; METABOLISM; MIDDLE AGED; MONONUCLEAR CELL;

AGED; ALLELES; ANIMALS; APOLIPOPROTEINS E; CAROTID ARTERY DISEASES; ENDARTERECTOMY, CAROTID; FEMALE; GENE EXPRESSION PROFILING; GENETIC PREDISPOSITION TO DISEASE; GENOTYPE; HISTONE DEACETYLASES; HUMANS; LEUKOCYTES, MONONUCLEAR; MALE; MICE; MICE, KNOCKOUT; MIDDLE AGED; PLAQUE, ATHEROSCLEROTIC; POLYMORPHISM, SINGLE NUCLEOTIDE; REPRESSOR PROTEINS; RNA, MESSENGER; STROKE;

EID: 84920138688     PISSN: 00392499     EISSN: 15244628     Source Type: Journal    
DOI: 10.1161/STROKEAHA.114.007213     Document Type: Article

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