메뉴 건너뛰기




Volumn 79, Issue 2, 2015, Pages 136-147

Addressing population-specific multiple testing burdens in genetic association studies

Author keywords

Autocorrelation; Genome wide threshold; GWAS; HapMap; Linkage disequilibrium

Indexed keywords

AFRICAN; ARTICLE; BREAST CANCER; CAUCASIAN; CHINESE; CUTANEOUS MELANOMA; EAST ASIAN; GENETIC ASSOCIATION; HAPLOTYPE MAP; HUMAN; PHENOTYPE; POPULATION GENETICS; PRIORITY JOURNAL; SINGLE NUCLEOTIDE POLYMORPHISM; ASIAN CONTINENTAL ANCESTRY GROUP; GENETICS; GENOME-WIDE ASSOCIATION STUDY; MELANOMA;

EID: 84923225139     PISSN: 00034800     EISSN: 14691809     Source Type: Journal    
DOI: 10.1111/ahg.12095     Document Type: Article
Times cited : (54)

References (39)
  • 2
    • 55449120805 scopus 로고    scopus 로고
    • Genetic mapping in human disease
    • Altshuler, D., Daly, M. J. & Lander, E. S. 2008. Genetic mapping in human disease. Science 322, 881-888.
    • (2008) Science , vol.322 , pp. 881-888
    • Altshuler, D.1    Daly, M.J.2    Lander, E.S.3
  • 4
    • 13444269543 scopus 로고    scopus 로고
    • Haploview: analysis and visualization of LD and haplotype maps
    • Barrett, J. C., Fry, B., Maller, J. & Daly, M. J. 2005. Haploview: analysis and visualization of LD and haplotype maps. Bioinformatics 21, 263-265.
    • (2005) Bioinformatics , vol.21 , pp. 263-265
    • Barrett, J.C.1    Fry, B.2    Maller, J.3    Daly, M.J.4
  • 6
    • 85007097364 scopus 로고
    • Controlling the false discovery rate-a practical and powerful approach to multiple testing
    • Benjamini, Y. & Hochberg, Y. 1995. Controlling the false discovery rate-a practical and powerful approach to multiple testing. J Roy Stat Soc Ser B 57, 289-300.
    • (1995) J Roy Stat Soc Ser B , vol.57 , pp. 289-300
    • Benjamini, Y.1    Hochberg, Y.2
  • 8
    • 0034781050 scopus 로고    scopus 로고
    • A simple correction for multiple comparisons in interval mapping genome scans
    • Cheverud, J. M. 2001. A simple correction for multiple comparisons in interval mapping genome scans. Heredity (Edinb) 87, 52-58.
    • (2001) Heredity (Edinb) , vol.87 , pp. 52-58
    • Cheverud, J.M.1
  • 9
    • 42249087793 scopus 로고    scopus 로고
    • Estimation of significance thresholds for genomewide association scans
    • Dudbridge, F. & Gusnanto, A. 2008. Estimation of significance thresholds for genomewide association scans. Genet Epidemiol 32, 227-234.
    • (2008) Genet Epidemiol , vol.32 , pp. 227-234
    • Dudbridge, F.1    Gusnanto, A.2
  • 10
    • 58249124501 scopus 로고    scopus 로고
    • Establishing an adjusted p-value threshold to control the family-wide type 1 error in genome wide association studies
    • Duggal, P., Gillanders, E. M., Holmes, T. N. & Bailey-Wilson, J. E. 2008. Establishing an adjusted p-value threshold to control the family-wide type 1 error in genome wide association studies. BMC Genomics 9, 516.
    • (2008) BMC Genomics , vol.9 , pp. 516
    • Duggal, P.1    Gillanders, E.M.2    Holmes, T.N.3    Bailey-Wilson, J.E.4
  • 11
    • 84865790047 scopus 로고    scopus 로고
    • An integrated encyclopedia of DNA elements in the human genome
    • Encode Project Consortium. 2012. An integrated encyclopedia of DNA elements in the human genome. Nature 489, 57-74.
    • (2012) Nature , vol.489 , pp. 57-74
  • 14
    • 43249090541 scopus 로고    scopus 로고
    • A multiple testing correction method for genetic association studies using correlated single nucleotide polymorphisms
    • Gao, X., Starmer, J. & Martin, E. R. 2008. A multiple testing correction method for genetic association studies using correlated single nucleotide polymorphisms. Genet Epidemiol 32, 361-369.
    • (2008) Genet Epidemiol , vol.32 , pp. 361-369
    • Gao, X.1    Starmer, J.2    Martin, E.R.3
  • 15
    • 66349103652 scopus 로고    scopus 로고
    • Rapid and accurate multiple testing correction and power estimation for millions of correlated markers
    • Han, B., Kang, H. M. & Eskin, E. 2009. Rapid and accurate multiple testing correction and power estimation for millions of correlated markers. PLoS Genet 5, e1000456.
    • (2009) PLoS Genet , vol.5 , pp. e1000456
    • Han, B.1    Kang, H.M.2    Eskin, E.3
  • 17
    • 0022211482 scopus 로고
    • Statistical properties of the number of recombination events in the history of a sample of DNA sequences
    • Hudson, R. R. & Kaplan, N. L. 1985. Statistical properties of the number of recombination events in the history of a sample of DNA sequences. Genetics 111, 147-164.
    • (1985) Genetics , vol.111 , pp. 147-164
    • Hudson, R.R.1    Kaplan, N.L.2
  • 18
    • 79959503826 scopus 로고    scopus 로고
    • The International HapMap Project
    • International Hapmap Consortium. 2003. The International HapMap Project. Nature 426, 789-796.
    • (2003) Nature , vol.426 , pp. 789-796
  • 19
    • 79959524146 scopus 로고    scopus 로고
    • A haplotype map of the human genome
    • International Hapmap Consortium. 2005. A haplotype map of the human genome. Nature 437, 1299-1320.
    • (2005) Nature , vol.437 , pp. 1299-1320
  • 22
    • 30744434862 scopus 로고    scopus 로고
    • Adjusting multiple testing in multilocus analyses using the eigenvalues of a correlation matrix
    • Li, J. & Ji, L. 2005. Adjusting multiple testing in multilocus analyses using the eigenvalues of a correlation matrix. Heredity (Edinb) 95, 221-227.
    • (2005) Heredity (Edinb) , vol.95 , pp. 221-227
    • Li, J.1    Ji, L.2
  • 23
    • 50249187303 scopus 로고    scopus 로고
    • On multiple-testing correction in genome-wide association studies
    • Moskvina, V. & Schmidt, K. M. 2008. On multiple-testing correction in genome-wide association studies. Genet Epidemiol 32, 567-573.
    • (2008) Genet Epidemiol , vol.32 , pp. 567-573
    • Moskvina, V.1    Schmidt, K.M.2
  • 24
    • 30344462556 scopus 로고    scopus 로고
    • Comparison of type I error for multiple test corrections in large single-nucleotide polymorphism studies using principal components versus haplotype blocking algorithms
    • Nicodemus, K. K., Liu, W., Chase, G. A., Tsai, Y. Y. & Fallin, M. D. 2005. Comparison of type I error for multiple test corrections in large single-nucleotide polymorphism studies using principal components versus haplotype blocking algorithms. BMC Genet 6(Suppl 1), S78.
    • (2005) BMC Genet , vol.6 , pp. S78
    • Nicodemus, K.K.1    Liu, W.2    Chase, G.A.3    Tsai, Y.Y.4    Fallin, M.D.5
  • 25
    • 1842539516 scopus 로고    scopus 로고
    • A simple correction for multiple testing for single-nucleotide polymorphisms in linkage disequilibrium with each other
    • Nyholt, D. R. 2004. A simple correction for multiple testing for single-nucleotide polymorphisms in linkage disequilibrium with each other. Am J Hum Genet 74, 765-769.
    • (2004) Am J Hum Genet , vol.74 , pp. 765-769
    • Nyholt, D.R.1
  • 26
    • 43249125992 scopus 로고    scopus 로고
    • Estimation of the multiple testing burden for genomewide association studies of nearly all common variants
    • Pe'er, I., Yelensky, R., Altshuler, D. & Daly, M. J. 2008. Estimation of the multiple testing burden for genomewide association studies of nearly all common variants. Genet Epidemiol 32, 381-385.
    • (2008) Genet Epidemiol , vol.32 , pp. 381-385
    • Pe'er, I.1    Yelensky, R.2    Altshuler, D.3    Daly, M.J.4
  • 27
    • 41149087694 scopus 로고    scopus 로고
    • CODA: convergence diagnosis and output analysis for MCMC
    • Plummer, M., Best, N., Cowles, K. & Vines, K. 2012. CODA: convergence diagnosis and output analysis for MCMC. R News 6, 7-11.
    • (2012) R News , vol.6 , pp. 7-11
    • Plummer, M.1    Best, N.2    Cowles, K.3    Vines, K.4
  • 28
    • 84923235172 scopus 로고    scopus 로고
    • v1.07. Available from:
    • Purcell, S. Plink (v1.07). Available from: .
    • Purcell, S.P.1
  • 30
    • 84923235171 scopus 로고    scopus 로고
    • R: A Language and Environment for Statistical Computing. R Foundation for Statistical Computing, Vienna, Austria.
    • R CODE TEAM. 2013. R: A Language and Environment for Statistical Computing. R Foundation for Statistical Computing, Vienna, Austria.
    • (2013)
  • 32
    • 0029741063 scopus 로고    scopus 로고
    • The future of genetic studies of complex human diseases
    • Risch, N. & Merikangas, K. 1996. The future of genetic studies of complex human diseases. Science 273, 1516-1517.
    • (1996) Science , vol.273 , pp. 1516-1517
    • Risch, N.1    Merikangas, K.2
  • 35
    • 84947402121 scopus 로고
    • Rectangular confidence regions for the means of multivariate normal distributions
    • Šidák, Z. 1967. Rectangular confidence regions for the means of multivariate normal distributions. J Am Stat Assoc 62, 626-633.
    • (1967) J Am Stat Assoc , vol.62 , pp. 626-633
    • Šidák, Z.1
  • 37
    • 79954594698 scopus 로고    scopus 로고
    • Correcting away the hidden heritability
    • Williams, S. M. & Haines, J. L. 2011. Correcting away the hidden heritability. Ann Hum Genet 75, 348-350.
    • (2011) Ann Hum Genet , vol.75 , pp. 348-350
    • Williams, S.M.1    Haines, J.L.2
  • 39
    • 67849101182 scopus 로고    scopus 로고
    • SNPinfo: integrating GWAS and candidate gene information into functional SNP selection for genetic association studies
    • Xu, Z. & Taylor, J. A. 2009. SNPinfo: integrating GWAS and candidate gene information into functional SNP selection for genetic association studies. Nucleic Acids Res 37, W600-W605.
    • (2009) Nucleic Acids Res , vol.37 , pp. W600-W605
    • Xu, Z.1    Taylor, J.A.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.