Comparative pharmacokinetics of triterpenic acids in normal and immunosuppressed rats after oral administration of Jujubae Fructus extract by UPLC-MS/MS

Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences

Volumn 1077-1078, Issue , 2018, Pages 13-21

  Li, Yao ^a   Guo, Sheng ^a   Hua, Tingting ^a   Wang, Yanyan ^b   Wei, Dandan ^a   Zhao, Ming ^a   Su, Shulan ^a   Duan, Jin ao ^a  

^a NANJING UNIVERSITY OF CHINESE MEDICINE   (China)

^b Lianyungang TCM Branch of Jiangsu Union Technical Institute   (China)

Author keywords

Immunosuppression; Pharmacokinetics; Triterpenic acids; Ziziphus jujuba

Indexed keywords

BODY FLUIDS; CHROMATOGRAPHY; DRUG PRODUCTS; LIQUID CHROMATOGRAPHY; MASS SPECTROMETRY; RATS;

CHEMICAL AND BIOLOGICALS; CHROMATOGRAPHIC SEPARATIONS; IMMUNOSUPPRESSION; PHARMACOKINETIC PARAMETERS; SIMULTANEOUS DETERMINATIONS; TRITERPENIC ACIDS; ULTRA PERFORMANCE LIQUID CHROMATOGRAPHY; ZIZIPHUS JUJUBA;

PHARMACOKINETICS;

ACETONITRILE; ALPHITOLIC ACID; AMMONIUM ACETATE; BETULIC ACID; BETULONIC ACID; CEANOTHIC ACID; EPICEANOTHIC ACID; JUJUBE EXTRACT; MASLINIC ACID; METHANOL; POMONIC ACID; TRITERPENE DERIVATIVE; TRITERPENIC ACID DERIVATIVE; UNCLASSIFIED DRUG; WATER; HERBACEOUS AGENT; TRITERPENE;

ANIMAL EXPERIMENT; AREA UNDER THE CURVE; ARTICLE; BLOOD SAMPLING; CONTROLLED STUDY; DRUG DETERMINATION; IMMUNOSUPPRESSIVE TREATMENT; JUJUBE; MALE; MAXIMUM CONCENTRATION; NONHUMAN; PLASMA CLEARANCE; PRIORITY JOURNAL; RAT; TANDEM MASS SPECTROMETRY; TIME TO MAXIMUM PLASMA CONCENTRATION; ULTRA PERFORMANCE LIQUID CHROMATOGRAPHY; ANIMAL; BLOOD; CHEMISTRY; DRUG STABILITY; IMMUNOCOMPROMISED PATIENT; ORAL DRUG ADMINISTRATION; REPRODUCIBILITY; SENSITIVITY AND SPECIFICITY; SPRAGUE DAWLEY RAT; STATISTICAL MODEL; ZIZIPHUS;

ADMINISTRATION, ORAL; ANIMALS; DRUG STABILITY; DRUGS, CHINESE HERBAL; IMMUNOCOMPROMISED HOST; LINEAR MODELS; MALE; RATS; RATS, SPRAGUE-DAWLEY; REPRODUCIBILITY OF RESULTS; SENSITIVITY AND SPECIFICITY; TRITERPENES; ZIZIPHUS;

EID: 85042774836     PISSN: 15700232     EISSN: 1873376X     Source Type: Journal    
DOI: 10.1016/j.jchromb.2018.01.026     Document Type: Article

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