메뉴 건너뛰기




Volumn 100, Issue 1, 2016, Pages 61-68

The intestinal microbiome and the liver transplant recipient: What we know and what we need to know

Author keywords

[No Author keywords available]

Indexed keywords

AMPHOTERICIN B; BACTERIAL EXTRACT; BETA GLUCAN; BIFIDOBACTERIUM BREVE EXTRACT; COLISTIN; GALACTOSE OLIGOSACCHARIDE; INULIN; LACTOBACILLUS CASEI EXTRACT; LACTOBACILLUS PARACASEI EXTRACT; LACTOBACILLUS PLANTARUM EXTRACT; LEUCONOSTOC MESENTEROIDES EXTRACT; PAEDIACOCCUS PENTOSACEUS EXTRACT; PECTIN; PREBIOTIC AGENT; PROBIOTIC AGENT; RNA 16S; TOBRAMYCIN; UNCLASSIFIED DRUG; IMMUNOSUPPRESSIVE AGENT;

EID: 84952631585     PISSN: 00411337     EISSN: None     Source Type: Journal    
DOI: 10.1097/TP.0000000000001008     Document Type: Review
Times cited : (40)

References (63)
  • 1
    • 32944466887 scopus 로고    scopus 로고
    • Ecological and evolutionary forces shaping microbial diversity in the human intestine
    • Ley RE, Peterson DA, Gordon JI. Ecological and evolutionary forces shaping microbial diversity in the human intestine. Cell. 2006;124:837-848.
    • (2006) Cell , vol.124 , pp. 837-848
    • Ley, R.E.1    Peterson, D.A.2    Gordon, J.I.3
  • 2
    • 84876287641 scopus 로고    scopus 로고
    • Linking intestinal homeostasis and liver disease
    • Schnabl B. Linking intestinal homeostasis and liver disease. Curr Opin Gastroenterol. 2013;29:264-270.
    • (2013) Curr Opin Gastroenterol , vol.29 , pp. 264-270
    • Schnabl, B.1
  • 3
    • 84861980130 scopus 로고    scopus 로고
    • Interactions between the microbiota and the immune system
    • Hooper LV, Littman DR, Macpherson AJ. Interactions between the microbiota and the immune system. Science. 2012;336:1268-1273.
    • (2012) Science , vol.336 , pp. 1268-1273
    • Hooper, L.V.1    Littman, D.R.2    Macpherson, A.J.3
  • 5
    • 84874491147 scopus 로고    scopus 로고
    • Comparative analysis of microbiome measurement platforms using latent variable structural equationmodeling
    • Wu X, Berkow K, Frank DN, et al. Comparative analysis of microbiome measurement platforms using latent variable structural equationmodeling. BMC Bioinformatics. 2013;14:79.
    • (2013) BMC Bioinformatics , vol.14 , pp. 79
    • Wu, X.1    Berkow, K.2    Frank, D.N.3
  • 7
    • 66349110620 scopus 로고    scopus 로고
    • Toll-like receptors as targets in chronic liver diseases
    • Mencin A, Kluwe J, Schwabe RF. Toll-like receptors as targets in chronic liver diseases. Gut. 2009;58:704-720.
    • (2009) Gut , vol.58 , pp. 704-720
    • Mencin, A.1    Kluwe, J.2    Schwabe, R.F.3
  • 8
    • 35948958955 scopus 로고    scopus 로고
    • TLR4 enhances TGF-beta signaling and hepatic fibrosis
    • Seki E, DeMinicis S, Osterreicher CH, et al. TLR4 enhances TGF-beta signaling and hepatic fibrosis. Nat Med. 2007;13:1324-1332.
    • (2007) Nat Med , vol.13 , pp. 1324-1332
    • Seki, E.1    DeMinicis, S.2    Osterreicher, C.H.3
  • 9
    • 84871305315 scopus 로고    scopus 로고
    • Gut bacteria drive Kupffer cell expansion via MAMP-mediated ICAM-1 induction on sinusoidal endothelium and influence preservation-reperfusion injury after orthotopic liver transplantation
    • Corbitt N, Kimura S, Isse K, et al. Gut bacteria drive Kupffer cell expansion via MAMP-mediated ICAM-1 induction on sinusoidal endothelium and influence preservation-reperfusion injury after orthotopic liver transplantation. Am J Pathol. 2013;182:180-191.
    • (2013) Am J Pathol , vol.182 , pp. 180-191
    • Corbitt, N.1    Kimura, S.2    Isse, K.3
  • 11
    • 84870841986 scopus 로고    scopus 로고
    • Pathological bacterial translocation in cirrhosis: Pathophysiology, diagnosis and clinical implications
    • Bellot P, Francés R, Such J. Pathological bacterial translocation in cirrhosis: pathophysiology, diagnosis and clinical implications. Liver Int. 2013; 33:31-39.
    • (2013) Liver Int , vol.33 , pp. 31-39
    • Bellot, P.1    Francés, R.2    Such, J.3
  • 12
    • 0034794067 scopus 로고    scopus 로고
    • Small intestinal bacterial overgrowth in patients with cirrhosis: Prevalence and relation with spontaneous bacterial peritonitis
    • Bauer TM, Steinbröckner B, Brinkmann FE, et al. Small intestinal bacterial overgrowth in patients with cirrhosis: prevalence and relation with spontaneous bacterial peritonitis. Am J Gastroenterol. 2001;96:2962-2967.
    • (2001) Am J Gastroenterol , vol.96 , pp. 2962-2967
    • Bauer, T.M.1    Steinbröckner, B.2    Brinkmann, F.E.3
  • 13
    • 77449131229 scopus 로고    scopus 로고
    • Small-intestinal bacterial overgrowth in cirrhosis is related to the severity of liver disease
    • Pande C, Kumar A, Sarin SK. Small-intestinal bacterial overgrowth in cirrhosis is related to the severity of liver disease. Aliment Pharmacol Ther. 2009;29:1273-1281.
    • (2009) Aliment Pharmacol Ther , vol.29 , pp. 1273-1281
    • Pande, C.1    Kumar, A.2    Sarin, S.K.3
  • 14
    • 79960714764 scopus 로고    scopus 로고
    • Characterization of fecal microbial communities in patients with liver cirrhosis
    • Chen Y, Yang F, Lu H, et al. Characterization of fecal microbial communities in patients with liver cirrhosis. Hepatology. 2011;54:562-572.
    • (2011) Hepatology , vol.54 , pp. 562-572
    • Chen, Y.1    Yang, F.2    Lu, H.3
  • 15
    • 84907225684 scopus 로고    scopus 로고
    • Alterations of the human gut microbiome in liver cirrhosis
    • Qin N, Yang F, Li A, et al. Alterations of the human gut microbiome in liver cirrhosis. Nature. 2014;513:59-64.
    • (2014) Nature , vol.513 , pp. 59-64
    • Qin, N.1    Yang, F.2    Li, A.3
  • 16
    • 84876294967 scopus 로고    scopus 로고
    • Modulation of the fecal bile acid profile by gut microbiota in cirrhosis
    • Kakiyama G, Pandak WM, Gillevet PM, et al. Modulation of the fecal bile acid profile by gut microbiota in cirrhosis. J Hepatol. 2013;58:949-955.
    • (2013) J Hepatol , vol.58 , pp. 949-955
    • Kakiyama, G.1    Pandak, W.M.2    Gillevet, P.M.3
  • 17
    • 84883442887 scopus 로고    scopus 로고
    • Cirrhosis, bile acids and gut microbiota: Unraveling a complex relationship
    • Ridlon JM, Alves JM, Hylemon PB, et al. Cirrhosis, bile acids and gut microbiota: unraveling a complex relationship. Gut Microbes. 2013;4: 382-387.
    • (2013) Gut Microbes , vol.4 , pp. 382-387
    • Ridlon, J.M.1    Alves, J.M.2    Hylemon, P.B.3
  • 18
    • 0037372737 scopus 로고    scopus 로고
    • Oral bile acids reduce bacterial overgrowth, bacterial translocation, and endotoxemia in cirrhotic rats
    • Lorenzo-Zñiga V, Bartolí R, Planas R, et al. Oral bile acids reduce bacterial overgrowth, bacterial translocation, and endotoxemia in cirrhotic rats. Hepatology. 2003;37:551-557.
    • (2003) Hepatology , vol.37 , pp. 551-557
    • Lorenzo-Zñiga, V.1    Bartolí, R.2    Planas, R.3
  • 20
    • 0032005021 scopus 로고    scopus 로고
    • Translocated intestinal bacteria cause spontaneous bacterial peritonitis in cirrhotic rats: Molecular epidemiologic evidence
    • Llovet JM, Bartolí R, March F, et al. Translocated intestinal bacteria cause spontaneous bacterial peritonitis in cirrhotic rats: molecular epidemiologic evidence. J Hepatol. 1998;28:307-313.
    • (1998) J Hepatol , vol.28 , pp. 307-313
    • Llovet, J.M.1    Bartolí, R.2    March, F.3
  • 21
    • 84885480599 scopus 로고    scopus 로고
    • Large-scale survey of gutmicrobiota associated with MHE Via 16S rRNA-based pyrosequencing
    • Zhang Z, Zhai H, Geng J, et al. Large-scale survey of gutmicrobiota associated with MHE Via 16S rRNA-based pyrosequencing. Am J Gastroenterol. 2013;108:1601-1611.
    • (2013) Am J Gastroenterol , vol.108 , pp. 1601-1611
    • Zhang, Z.1    Zhai, H.2    Geng, J.3
  • 22
    • 58149399422 scopus 로고    scopus 로고
    • Serum and ascitic fluid bacterial DNA: A new independent prognostic factor in noninfected patients with cirrhosis
    • Zapater P, Francés R, González-Navajas JM, et al. Serum and ascitic fluid bacterial DNA: A new independent prognostic factor in noninfected patients with cirrhosis. Hepatology. 2008;48:1924-1931.
    • (2008) Hepatology , vol.48 , pp. 1924-1931
    • Zapater, P.1    Francés, R.2    González-Navajas, J.M.3
  • 23
    • 84859717987 scopus 로고    scopus 로고
    • Prevention of acute kidney injury in a rodent model of cirrhosis following selective gut decontamination is associated with reduced renal TLR4 expression
    • Shah N, Dhar D, El ZahraaMohammed F, et al. Prevention of acute kidney injury in a rodent model of cirrhosis following selective gut decontamination is associated with reduced renal TLR4 expression. J Hepatol. 2012; 56:1047-1053.
    • (2012) J Hepatol , vol.56 , pp. 1047-1053
    • Shah, N.1    Dhar, D.2    El ZahraaMohammed, F.3
  • 24
    • 84898830272 scopus 로고    scopus 로고
    • Altered profile of human gut microbiome is associated with cirrhosis and its complications
    • Bajaj JS, Heuman DM, Hylemon PB, et al. Altered profile of human gut microbiome is associated with cirrhosis and its complications. J Hepatol. 2014;60:940-947.
    • (2014) J Hepatol , vol.60 , pp. 940-947
    • Bajaj, J.S.1    Heuman, D.M.2    Hylemon, P.B.3
  • 26
    • 83655180869 scopus 로고    scopus 로고
    • Intestinal microbiota and innate immunityrelated gene alteration in cirrhotic rats with liver transplantation
    • Xie YR, Liu SL, Liu X, et al. Intestinal microbiota and innate immunityrelated gene alteration in cirrhotic rats with liver transplantation. Transplant Proc. 2011;43:3973-3979.
    • (2011) Transplant Proc , vol.43 , pp. 3973-3979
    • Xie, Y.R.1    Liu, S.L.2    Liu, X.3
  • 27
    • 84876144358 scopus 로고    scopus 로고
    • Assessment of microbiome variation during the perioperative period in liver transplant patients: A retrospective analysis
    • Lu H, He J, Wu Z, et al. Assessment of microbiome variation during the perioperative period in liver transplant patients: A retrospective analysis. Microb Ecol. 2013;65:781-791.
    • (2013) Microb Ecol , vol.65 , pp. 781-791
    • Lu, H.1    He, J.2    Wu, Z.3
  • 28
    • 84862929034 scopus 로고    scopus 로고
    • Changes of gut bacteria and immune parameters in liver transplant recipients
    • Wu ZW, Ling ZX, Lu HF, et al. Changes of gut bacteria and immune parameters in liver transplant recipients. Hepatobiliary Pancreat Dis Int. 2012;11:40-50.
    • (2012) Hepatobiliary Pancreat Dis Int , vol.11 , pp. 40-50
    • Wu, Z.W.1    Ling, Z.X.2    Lu, H.F.3
  • 29
    • 0023835746 scopus 로고
    • Selective bowel decontamination to decrease gram-negative aerobic bacterial and Candida colonization and prevent infection after orthotopic liver transplantation
    • Wiesner RH, Hermans PE, Rakela J, et al. Selective bowel decontamination to decrease gram-negative aerobic bacterial and Candida colonization and prevent infection after orthotopic liver transplantation. Transplantation. 1988;45:570-574.
    • (1988) Transplantation , vol.45 , pp. 570-574
    • Wiesner, R.H.1    Hermans, P.E.2    Rakela, J.3
  • 30
    • 3242790272 scopus 로고    scopus 로고
    • The role of selective digestive decontamination for reducing infection in patients undergoing liver transplantation: A systematic review and meta-Analysis
    • Safdar N, Said A, Lucey MR. The role of selective digestive decontamination for reducing infection in patients undergoing liver transplantation: A systematic review and meta-Analysis. Liver Transpl. 2004;10:817-827.
    • (2004) Liver Transpl , vol.10 , pp. 817-827
    • Safdar, N.1    Said, A.2    Lucey, M.R.3
  • 31
    • 0031972915 scopus 로고    scopus 로고
    • Selective bowel decontamination of recipients for prevention against liver injury following orthotopic liver transplantation: Evaluation with rat models
    • Arai M, Mochida S, Ohno A, et al. Selective bowel decontamination of recipients for prevention against liver injury following orthotopic liver transplantation: evaluation with rat models. Hepatology. 1998;27: 123-127.
    • (1998) Hepatology , vol.27 , pp. 123-127
    • Arai, M.1    Mochida, S.2    Ohno, A.3
  • 32
    • 0037182875 scopus 로고    scopus 로고
    • A randomized, prospective, double-blinded evaluation of selective bowel decontamination in liver transplantation
    • Hellinger WC, Yao JD, Alvarez S, et al. A randomized, prospective, double-blinded evaluation of selective bowel decontamination in liver transplantation. Transplantation. 2002;73:1904-1909.
    • (2002) Transplantation , vol.73 , pp. 1904-1909
    • Hellinger, W.C.1    Yao, J.D.2    Alvarez, S.3
  • 33
    • 84870683317 scopus 로고    scopus 로고
    • Impact of rifaximin use for hepatic encephalopathy on the risk of early post-Transplant infections in liver transplant recipients
    • Sun HY, Wagener M, Cacciarelli TV, et al. Impact of rifaximin use for hepatic encephalopathy on the risk of early post-Transplant infections in liver transplant recipients. Clin Transplant. 2012;26:849-852.
    • (2012) Clin Transplant , vol.26 , pp. 849-852
    • Sun, H.Y.1    Wagener, M.2    Cacciarelli, T.V.3
  • 34
    • 84899648301 scopus 로고    scopus 로고
    • Impact of pretransplant rifaximin therapy on early post-liver transplant infections
    • Esfeh JM, Hanouneh IA, Koval CE, et al. Impact of pretransplant rifaximin therapy on early post-liver transplant infections. Liver Transpl. 2014;20: 544-551.
    • (2014) Liver Transpl , vol.20 , pp. 544-551
    • Esfeh, J.M.1    Hanouneh, I.A.2    Koval, C.E.3
  • 35
    • 0029051550 scopus 로고
    • FK506 increases permeability in rat intestine by inhibiting mitochondrial function
    • Madsen KL, YancharNL, Sigalet DL, et al. FK506 increases permeability in rat intestine by inhibiting mitochondrial function. Gastroenterology. 1995; 109:107-114.
    • (1995) Gastroenterology , vol.109 , pp. 107-114
    • Madsen, K.L.1    Yancharnl Sigalet, D.L.2
  • 36
    • 0031749892 scopus 로고    scopus 로고
    • The effect of tacrolimus (FK506) on intestinal barrier function and cellular energy production in humans
    • Gabe SM, Bjarnason I, Tolou-Ghamari Z, et al. The effect of tacrolimus (FK506) on intestinal barrier function and cellular energy production in humans. Gastroenterology. 1998;115:67-74.
    • (1998) Gastroenterology , vol.115 , pp. 67-74
    • Gabe, S.M.1    Bjarnason, I.2    Tolou-Ghamari, Z.3
  • 37
    • 0038782027 scopus 로고    scopus 로고
    • Effect of chronic administration of tacrolimus and cyclosporine on human gastrointestinal permeability
    • Parrilli G, Abazia C, Sarnelli G, et al. Effect of chronic administration of tacrolimus and cyclosporine on human gastrointestinal permeability. Liver Transpl. 2003;9:484-488.
    • (2003) Liver Transpl , vol.9 , pp. 484-488
    • Parrilli, G.1    Abazia, C.2    Sarnelli, G.3
  • 38
    • 84864401253 scopus 로고    scopus 로고
    • Protective role of p70S6K in intestinal ischemia/reperfusion injury in mice
    • Ban K, Kozar RA. Protective role of p70S6K in intestinal ischemia/reperfusion injury in mice. PLoS One. 2012;7:e41584.
    • (2012) PLoS One , vol.7 , pp. e41584
    • Ban, K.1    Kozar, R.A.2
  • 39
    • 84864343040 scopus 로고    scopus 로고
    • Structural shifts of fecal microbial communities in rats with acute rejection after liver transplantation
    • Xie Y, Luo Z, Li Z, et al. Structural shifts of fecal microbial communities in rats with acute rejection after liver transplantation. Microb Ecol. 2012;64: 546-554.
    • (2012) Microb Ecol , vol.64 , pp. 546-554
    • Xie, Y.1    Luo, Z.2    Li, Z.3
  • 40
    • 84921358908 scopus 로고    scopus 로고
    • Intestinal microbial variation may predict early acute rejection after liver transplantation in rats
    • Ren Z, Jiang J, Lu H, et al. Intestinal microbial variation may predict early acute rejection after liver transplantation in rats. Transplantation. 2014; 98:844-852.
    • (2014) Transplantation , vol.98 , pp. 844-852
    • Ren, Z.1    Jiang, J.2    Lu, H.3
  • 41
    • 84878432985 scopus 로고    scopus 로고
    • Probiotics, prebiotics and immunomodulation of gut mucosal defences: Homeostasis and immunopathology
    • Hardy H, Harris J, Lyon E, Beal J, Foey AD. Probiotics, prebiotics and immunomodulation of gut mucosal defences: homeostasis and immunopathology. Nutrients. 2013;5:1869-1912.
    • (2013) Nutrients , vol.5 , pp. 1869-1912
    • Hardy, H.1    Harris, J.2    Lyon, E.3    Beal, J.4    Foey, A.D.5
  • 43
    • 33947169259 scopus 로고    scopus 로고
    • Probiotics and prebiotics: Effects on diarrhea
    • de Vrese M, Marteau PR. Probiotics and prebiotics: effects on diarrhea. J Nutr. 2007;137(3 Suppl 2):803S-811S.
    • (2007) J Nutr , vol.137 , Issue.3 , pp. 803S-811S
    • De Vrese, M.1    Marteau, P.R.2
  • 44
    • 84873100864 scopus 로고    scopus 로고
    • Probiotic/synbiotic therapy for treating critically ill patients from a gut microbiota perspective
    • Shimizu K, Ogura H, Asahara T, et al. Probiotic/synbiotic therapy for treating critically ill patients from a gut microbiota perspective. Dig Dis Sci. 2013;58:23-32.
    • (2013) Dig Dis Sci. , vol.58 , pp. 23-32
    • Shimizu, K.1    Ogura, H.2    Asahara, T.3
  • 45
    • 0037099390 scopus 로고    scopus 로고
    • Early enteral supply of lactobacillus and fiber versus selective bowel decontamination: A controlled trial in liver transplant recipients
    • Rayes N, Seehofer D, Hansen S, et al. Early enteral supply of lactobacillus and fiber versus selective bowel decontamination: A controlled trial in liver transplant recipients. Transplantation. 2002;74:123-127.
    • (2002) Transplantation , vol.74 , pp. 123-127
    • Rayes, N.1    Seehofer, D.2    Hansen, S.3
  • 46
    • 11844284850 scopus 로고    scopus 로고
    • Supply of pre-And probiotics reduces bacterial infection rates after liver transplantation-A randomized, double-blind trial
    • Rayes N, Seehofer D, Theruvath T, et al. Supply of pre-And probiotics reduces bacterial infection rates after liver transplantation-A randomized, double-blind trial. Am J Transplant. 2005;5:125-130.
    • (2005) Am J Transplant , vol.5 , pp. 125-130
    • Rayes, N.1    Seehofer, D.2    Theruvath, T.3
  • 47
    • 79952990394 scopus 로고    scopus 로고
    • Perioperative synbiotic treatment to prevent infectious complications in patients after elective living donor liver transplantation: A prospective randomized study
    • Eguchi S, Takatsuki M, Hidaka M, et al. Perioperative synbiotic treatment to prevent infectious complications in patients after elective living donor liver transplantation: A prospective randomized study. Am J Surg. 2011; 201:498-502.
    • (2011) Am J Surg , vol.201 , pp. 498-502
    • Eguchi, S.1    Takatsuki, M.2    Hidaka, M.3
  • 48
    • 80053218812 scopus 로고    scopus 로고
    • Protective effect of probiotics on intestinal barrier function in malnourished rats after liver transplantation
    • Ren ZG, Liu H, Jiang JW, et al. Protective effect of probiotics on intestinal barrier function in malnourished rats after liver transplantation. Hepatobiliary Pancreat Dis Int. 2011;10:489-496.
    • (2011) Hepatobiliary Pancreat Dis Int , vol.10 , pp. 489-496
    • Ren, Z.G.1    Liu, H.2    Jiang, J.W.3
  • 49
    • 84939896548 scopus 로고    scopus 로고
    • Effect of intestinal microbiota alteration on hepatic damage in rats with acute rejection after liver transplantation
    • Xie Y, Chen H, Zhu B, et al. Effect of intestinal microbiota alteration on hepatic damage in rats with acute rejection after liver transplantation. Microb Ecol. 2014;68:871-880.
    • (2014) Microb Ecol , vol.68 , pp. 871-880
    • Xie, Y.1    Chen, H.2    Zhu, B.3
  • 50
    • 33645859594 scopus 로고    scopus 로고
    • Protective role of supplement with foreign Bifidobacterium and Lactobacillus in experimental hepatic ischemiareperfusion injury
    • Xing HC, Li LJ, Xu KJ, et al. Protective role of supplement with foreign Bifidobacterium and Lactobacillus in experimental hepatic ischemiareperfusion injury. J Gastroenterol Hepatol. 2006;21:647-656.
    • (2006) J Gastroenterol Hepatol , vol.21 , pp. 647-656
    • Xing, H.C.1    Li, L.J.2    Xu, K.J.3
  • 51
    • 84866738529 scopus 로고    scopus 로고
    • Transfer of intestinal microbiota from lean donors increases insulin sensitivity in individuals with metabolic syndrome
    • 913-916e7e917
    • Vrieze A, Van Nood E, Holleman F, et al. Transfer of intestinal microbiota from lean donors increases insulin sensitivity in individuals with metabolic syndrome. Gastroenterology. 2012;143:913-916.e7 e917.
    • (2012) Gastroenterology , vol.143
    • Vrieze, A.1    Van Nood, E.2    Holleman, F.3
  • 52
    • 34347399563 scopus 로고    scopus 로고
    • Metabolic endotoxemia initiates obesity and insulin resistance
    • Cani PD, Amar J, Iglesias MA, et al. Metabolic endotoxemia initiates obesity and insulin resistance. Diabetes. 2007;56:1761-1772.
    • (2007) Diabetes , vol.56 , pp. 1761-1772
    • Cani, P.D.1    Amar, J.2    Iglesias, M.A.3
  • 53
    • 84883110880 scopus 로고    scopus 로고
    • Richness of human gut microbiome correlates with metabolic markers
    • Le Chatelier E, Nielsen T, Qin J, et al. Richness of human gut microbiome correlates with metabolic markers. Nature. 2013;500:541-546.
    • (2013) Nature , vol.500 , pp. 541-546
    • Le Chatelier, E.1    Nielsen, T.2    Qin, J.3
  • 54
    • 84895077527 scopus 로고    scopus 로고
    • A gut microbiota-Targeted dietary intervention for amelioration of chronic inflammation underlying metabolic syndrome
    • Xiao S, Fei N, Pang X, et al. A gut microbiota-Targeted dietary intervention for amelioration of chronic inflammation underlying metabolic syndrome. FEMS Microbiol Ecol. 2014;87:357-367.
    • (2014) FEMS Microbiol Ecol , vol.87 , pp. 357-367
    • Xiao, S.1    Fei, N.2    Pang, X.3
  • 55
    • 84876563088 scopus 로고    scopus 로고
    • Intestinalmicrobial metabolismof phosphatidylcholine and cardiovascular risk
    • TangWH, Wang Z, Levison BS, et al. Intestinalmicrobial metabolismof phosphatidylcholine and cardiovascular risk.NEngl J Med. 2013;368:1575-1584.
    • (2013) NEngl J Med , vol.368 , pp. 1575-1584
    • Tang, W.H.1    Wang, Z.2    Levison, B.S.3
  • 56
    • 84938906986 scopus 로고    scopus 로고
    • Gut bacteria products prevent AKI induced by ischemia-reperfusion
    • Andrade-Oliveira V, Amano MT, Correa-Costa M, et al. Gut bacteria products prevent AKI induced by ischemia-reperfusion. J Am Soc Nephrol. 2015;26:1877-1888.
    • (2015) J Am Soc Nephrol , vol.26 , pp. 1877-1888
    • Andrade-Oliveira, V.1    Amano, M.T.2    Correa-Costa, M.3
  • 57
    • 84888638819 scopus 로고    scopus 로고
    • The microbiome and cancer
    • Schwabe RF, Jobin C. The microbiome and cancer. Nat Rev Cancer. 2013;13:800-812.
    • (2013) Nat Rev Cancer , vol.13 , pp. 800-812
    • Schwabe, R.F.1    Jobin, C.2
  • 58
    • 68949148889 scopus 로고    scopus 로고
    • Increased intestinal permeability and tight junction alterations in nonalcoholic fatty liver disease
    • Miele L, Valenza V, La Torre G, et al. Increased intestinal permeability and tight junction alterations in nonalcoholic fatty liver disease. Hepatology. 2009;49:1877-1887.
    • (2009) Hepatology , vol.49 , pp. 1877-1887
    • Miele, L.1    Valenza, V.2    La Torre, G.3
  • 59
    • 84856957894 scopus 로고    scopus 로고
    • Inflammasome-mediated dysbiosis regulates progression of NAFLD and obesity
    • Henao-Mejia J, Elinav E, Jin C, et al. Inflammasome-mediated dysbiosis regulates progression of NAFLD and obesity. Nature. 2012;482: 179-185.
    • (2012) Nature , vol.482 , pp. 179-185
    • Henao-Mejia, J.1    Elinav, E.2    Jin, C.3
  • 60
    • 84904414417 scopus 로고    scopus 로고
    • Primary sclerosing cholangitis and the microbiota: Current knowledge and perspectives on etiopathogenesis and emerging therapies
    • Tabibian JH, O'Hara SP, Lindor KD. Primary sclerosing cholangitis and the microbiota: current knowledge and perspectives on etiopathogenesis and emerging therapies. Scand J Gastroenterol. 2014;49:901-908.
    • (2014) Scand J Gastroenterol , vol.49 , pp. 901-908
    • Tabibian, J.H.1    O'Hara, S.P.2    Lindor, K.D.3
  • 61
    • 84886284340 scopus 로고    scopus 로고
    • Role of the intestinalmicrobiome in liver disease
    • Henao-Mejia J, Elinav E, Thaiss CA, et al. Role of the intestinalmicrobiome in liver disease. J Autoimmun. 2013;46:66-73.
    • (2013) J Autoimmun , vol.46 , pp. 66-73
    • Henao-Mejia, J.1    Elinav, E.2    Thaiss, C.A.3
  • 62
    • 84866383592 scopus 로고    scopus 로고
    • Profound impact of gut homeostasis on chemically-induced pro-Tumorigenic inflammation and hepatocarcinogenesis in rats
    • Zhang HL, Yu LX, Yang W, et al. Profound impact of gut homeostasis on chemically-induced pro-Tumorigenic inflammation and hepatocarcinogenesis in rats. J Hepatol. 2012;57:803-812.
    • (2012) J Hepatol , vol.57 , pp. 803-812
    • Zhang, H.L.1    Yu, L.X.2    Yang, W.3
  • 63
    • 84879888338 scopus 로고    scopus 로고
    • Obesity-induced gut microbial metabolite promotes liver cancer through senescence secretome
    • Yoshimoto S, Loo TM, Atarashi K, et al. Obesity-induced gut microbial metabolite promotes liver cancer through senescence secretome. Nature. 2013;499:97-101.
    • (2013) Nature , vol.499 , pp. 97-101
    • Yoshimoto, S.1    Loo, T.M.2    Atarashi, K.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.