Dicer-2-Dependent Generation of Viral DNA from Defective Genomes of RNA Viruses Modulates Antiviral Immunity in Insects

Cell Host and Microbe

Volumn 23, Issue 3, 2018, Pages 353-365.e8

  Poirier, Enzo Z ^a,b   Goic, Bertsy ^a   Tomé Poderti, Lorena ^a   Frangeul, Lionel ^a   Boussier, Jérémy ^c   Gausson, Valérie ^a   Blanc, Hervé ^a   Vallet, Thomas ^a   Loyd, Hyelee ^d   Levi, Laura I ^a   Lanciano, Sophie ^e   Baron, Chloé ^a   Merkling, Sarah H ^f   Lambrechts, Louis ^f   Mirouze, Marie ^e   Carpenter, Susan ^d   Vignuzzi, Marco ^a   Saleh, Maria Carla ^a  

^a INSTITUT PASTEUR   (France)

^b UNIVERSITÉ PARIS DESCARTES   (France)

^c INSERM   (France)

^d IOWA STATE UNIVERSITY   (United States)

^e INSTITUT DE RECHERCHE POUR LE DÉVELOPPEMENT   (France)

^f CNRS   (France)

Author keywords

arbovirus; circular viral DNA; defective viral genomes; Dicer 2; insect; persistence; RNA virus; RNAi

Indexed keywords

CIRCULAR DNA; DICER; HELICASE; VIRUS DNA; ANTIVIRUS AGENT; DCR-2 PROTEIN, DROSOPHILA; DEAD BOX PROTEIN; DROSOPHILA PROTEIN; RIBONUCLEASE III; RNA HELICASE; SMALL INTERFERING RNA; VIRUS RNA;

ADAPTIVE IMMUNITY; ADULT; AEDES AEGYPTI; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BIOGENESIS; CELL LYSATE; CHIKUNGUNYA; CHIKUNGUNYA VIRUS; CHIMERA; CONTROLLED STUDY; DROSOPHILA; FEMALE; HUMAN; INNATE IMMUNITY; MOSQUITO; NONHUMAN; PERSISTENT VIRUS INFECTION; PRIORITY JOURNAL; REPLICON; RETROPOSON; REVERSE TRANSCRIPTION; RNA VIRUS; RNA VIRUS INFECTION; SINDBIS VIRUS; TRANSPOSON; VIRUS GENOME; VIRUS IMMUNITY; VIRUS LOAD; ANIMAL; ARBOVIRUS; GENETICS; HOST PATHOGEN INTERACTION; IMMUNOLOGY; METABOLISM; PATHOGENICITY; POINT MUTATION; RNA INTERFERENCE; VIRUS GENE; VIRUS REPLICATION;

ANIMALS; ANTIVIRAL AGENTS; ARBOVIRUSES; CULICIDAE; DEAD-BOX RNA HELICASES; DNA, VIRAL; DROSOPHILA; DROSOPHILA PROTEINS; GENES, VIRAL; GENOME, VIRAL; HOST-PATHOGEN INTERACTIONS; POINT MUTATION; RIBONUCLEASE III; RNA HELICASES; RNA INTERFERENCE; RNA VIRUS INFECTIONS; RNA VIRUSES; RNA, SMALL INTERFERING; RNA, VIRAL; VIRAL LOAD; VIRUS REPLICATION;

EID: 85042496545     PISSN: 19313128     EISSN: 19346069     Source Type: Journal    
DOI: 10.1016/j.chom.2018.02.001     Document Type: Article

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