-
1
-
-
70450198396
-
Epithelial-mesenchymal transitions in development and disease
-
Thiery, J. P., Acloque, H., Huang, R. Y. & Nieto, M. A. Epithelial-mesenchymal transitions in development and disease. Cell. 139, 871-890 (2009).
-
(2009)
Cell.
, vol.139
, pp. 871-890
-
-
Thiery, J.P.1
Acloque, H.2
Huang, R.Y.3
Nieto, M.A.4
-
2
-
-
33244463813
-
Complex networks orchestrate epithelial-mesenchymal transitions
-
Thiery, J. P. & Sleeman, J. P. Complex networks orchestrate epithelial-mesenchymal transitions. Nat Rev Mol Cell Biol. 7, 131-142 (2006).
-
(2006)
Nat Rev Mol Cell Biol.
, vol.7
, pp. 131-142
-
-
Thiery, J.P.1
Sleeman, J.P.2
-
3
-
-
43049165453
-
The epithelial-mesenchymal transition generates cells with properties of stem cells
-
Mani, S. A. et al. The epithelial-mesenchymal transition generates cells with properties of stem cells. Cell. 133, 704-715 (2008).
-
(2008)
Cell.
, vol.133
, pp. 704-715
-
-
Mani, S.A.1
-
4
-
-
77956178360
-
EMT, cancer stem cells and drug resistance, an emerging axis of evil in the war on cancer
-
Singh, A. & Settleman, J. EMT, cancer stem cells and drug resistance, an emerging axis of evil in the war on cancer. Oncogene. 29, 4741-4751 (2010).
-
(2010)
Oncogene.
, vol.29
, pp. 4741-4751
-
-
Singh, A.1
Settleman, J.2
-
5
-
-
84873811988
-
Circulating breast tumor cells exhibit dynamic changes in epithelial and mesenchymal composition
-
Yu, M. et al. Circulating breast tumor cells exhibit dynamic changes in epithelial and mesenchymal composition. Science. 339, 580-584 (2013).
-
(2013)
Science.
, vol.339
, pp. 580-584
-
-
Yu, M.1
-
6
-
-
0023197175
-
Urokinase-type plasminogen activator, proenzyme, receptor, and inhibitors
-
Blasi, F., Vassalli, J. D. & Dano, K. Urokinase-type plasminogen activator, proenzyme, receptor, and inhibitors. J Cell Biol. 104, 801-804 (1987).
-
(1987)
J Cell Biol.
, vol.104
, pp. 801-804
-
-
Blasi, F.1
Vassalli, J.D.2
Dano, K.3
-
7
-
-
0030788411
-
The urokinase-type plasminogen activator system in cancer metastasis, a review
-
Andreasen, P. A., Kjoller, L., Christensen, L. & Duffy, M. J. The urokinase-type plasminogen activator system in cancer metastasis, a review. Int J Cancer. 72, 1-22 (1997).
-
(1997)
Int J Cancer.
, vol.72
, pp. 1-22
-
-
Andreasen, P.A.1
Kjoller, L.2
Christensen, L.3
Duffy, M.J.4
-
8
-
-
0025995875
-
Protein structure and membrane anchorage of the cellular receptor for urokinase-type plasminogen activator
-
Ploug, M., Behrendt, N., Lober, D. & Dano, K. Protein structure and membrane anchorage of the cellular receptor for urokinase-type plasminogen activator. Semin Thromb Hemost. 17, 183-193 (1991).
-
(1991)
Semin Thromb Hemost.
, vol.17
, pp. 183-193
-
-
Ploug, M.1
Behrendt, N.2
Lober, D.3
Dano, K.4
-
9
-
-
0036906177
-
UPAR, a versatile signalling orchestrator
-
Blasi, F. & Carmeliet, P. uPAR, a versatile signalling orchestrator. Nat Rev Mol Cell Biol. 3, 932-943 (2002).
-
(2002)
Nat Rev Mol Cell Biol.
, vol.3
, pp. 932-943
-
-
Blasi, F.1
Carmeliet, P.2
-
10
-
-
20444478292
-
Dynamic assembly of the urokinase-type plasminogen activator signaling receptor complex determines the mitogenic activity of urokinase-type plasminogen activator
-
Jo, M. et al. Dynamic assembly of the urokinase-type plasminogen activator signaling receptor complex determines the mitogenic activity of urokinase-type plasminogen activator. J Biol Chem. 280, 17449-17457 (2005).
-
(2005)
J Biol Chem.
, vol.280
, pp. 17449-17457
-
-
Jo, M.1
-
12
-
-
34547610957
-
UPAR induces epithelial-mesenchymal transition in hypoxic breast cancer cells
-
Lester, R. D., Jo, M., Montel, V., Takimoto, S. & Gonias, S. L. uPAR induces epithelial-mesenchymal transition in hypoxic breast cancer cells. J Cell Biol. 178, 425-436 (2007).
-
(2007)
J Cell Biol.
, vol.178
, pp. 425-436
-
-
Lester, R.D.1
Jo, M.2
Montel, V.3
Takimoto, S.4
Gonias, S.L.5
-
13
-
-
69249111313
-
Reversibility of epithelial-mesenchymal transition (EMT) induced in breast cancer cells by activation of urokinase receptor-dependent cell signaling
-
Jo, M. et al. Reversibility of epithelial-mesenchymal transition (EMT) induced in breast cancer cells by activation of urokinase receptor-dependent cell signaling. J Biol Chem. 284, 22825-22833 (2009).
-
(2009)
J Biol Chem.
, vol.284
, pp. 22825-22833
-
-
Jo, M.1
-
14
-
-
0032478829
-
Binding of urokinase-type plasminogen activator to its receptor in MCF-7 cells activates extracellular signal-regulated kinase 1 and 2 which is required for increased cellular motility
-
Nguyen, D. H., Hussaini, I. M. & Gonias, S. L. Binding of urokinase-type plasminogen activator to its receptor in MCF-7 cells activates extracellular signal-regulated kinase 1 and 2 which is required for increased cellular motility. J Biol Chem. 273, 5802-8507 (1998).
-
(1998)
J Biol Chem.
, vol.273
, pp. 5802-8507
-
-
Nguyen, D.H.1
Hussaini, I.M.2
Gonias, S.L.3
-
15
-
-
0033959101
-
Extracellular signal-regulated kinase functions in the urokinase receptor-dependent pathway by which neutralization of low density lipoprotein receptor-related protein promotes fibrosarcoma cell migration and matrigel invasion
-
Webb, D. J., Nguyen, D. H. & Gonias, S. L. Extracellular signal-regulated kinase functions in the urokinase receptor-dependent pathway by which neutralization of low density lipoprotein receptor-related protein promotes fibrosarcoma cell migration and matrigel invasion. J Cell Sci. 113, 123-134 (2000).
-
(2000)
J Cell Sci.
, vol.113
, pp. 123-134
-
-
Webb, D.J.1
Nguyen, D.H.2
Gonias, S.L.3
-
16
-
-
13844256438
-
The urokinase plasminogen activator and its receptor, role in cell growth and apoptosis
-
Alfano, D. et al. The urokinase plasminogen activator and its receptor, role in cell growth and apoptosis. Thromb Haemost. 93, 205-211 (2005).
-
(2005)
Thromb Haemost.
, vol.93
, pp. 205-211
-
-
Alfano, D.1
-
17
-
-
0034782160
-
Endogenously produced urokinase-type plasminogen activator is a major determinant of the basal level of activated ERK/MAP kinase and prevents apoptosis in MDA-MB-231 breast cancer cells
-
Ma, Z., Webb, D. J., Jo, M. & Gonias, S. L. Endogenously produced urokinase-type plasminogen activator is a major determinant of the basal level of activated ERK/MAP kinase and prevents apoptosis in MDA-MB-231 breast cancer cells. J Cell Sci. 114, 3387-3396 (2001).
-
(2001)
J Cell Sci.
, vol.114
, pp. 3387-3396
-
-
Ma, Z.1
Webb, D.J.2
Jo, M.3
Gonias, S.L.4
-
18
-
-
33745841867
-
Urokinase signaling through its receptor protects against anoikis by increasing BCL-xL expression levels
-
Alfano, D., Iaccarino, I. & Stoppelli, M. P. Urokinase signaling through its receptor protects against anoikis by increasing BCL-xL expression levels. J Biol Chem. 281, 17758-17767 (2006).
-
(2006)
J Biol Chem.
, vol.281
, pp. 17758-17767
-
-
Alfano, D.1
Iaccarino, I.2
Stoppelli, M.P.3
-
19
-
-
78449305061
-
Cell signaling by urokinase-type plasminogen activator receptor induces stem cell-like properties in breast cancer cells
-
Jo, M. et al. Cell signaling by urokinase-type plasminogen activator receptor induces stem cell-like properties in breast cancer cells. Cancer Res. 70, 8948-8958 (2010).
-
(2010)
Cancer Res.
, vol.70
, pp. 8948-8958
-
-
Jo, M.1
-
20
-
-
67649910151
-
The urokinase receptor promotes cancer metastasis independently of urokinase-type plasminogen activator in mice
-
Jo, M., Takimoto, S., Montel, V. & Gonias, S. L. The urokinase receptor promotes cancer metastasis independently of urokinase-type plasminogen activator in mice. Am J Pathol. 175, 190-200 (2009).
-
(2009)
Am J Pathol.
, vol.175
, pp. 190-200
-
-
Jo, M.1
Takimoto, S.2
Montel, V.3
Gonias, S.L.4
-
21
-
-
84877930800
-
Direct evidence of the importance of vitronectin and its interaction with the urokinase receptor in tumor growth
-
Pirazzoli, V., Ferraris, G. M. & Sidenius, N. Direct evidence of the importance of vitronectin and its interaction with the urokinase receptor in tumor growth. Blood. 121, 2316-2323 (2013).
-
(2013)
Blood.
, vol.121
, pp. 2316-2323
-
-
Pirazzoli, V.1
Ferraris, G.M.2
Sidenius, N.3
-
22
-
-
84862650960
-
A transformation in the mechanism by which the urokinase receptor signals provides a selection advantage for estrogen receptor-expressing breast cancer cells in the absence of estrogen
-
Eastman, B. M., Jo, M., Webb, D. L., Takimoto, S. & Gonias, S. L. A transformation in the mechanism by which the urokinase receptor signals provides a selection advantage for estrogen receptor-expressing breast cancer cells in the absence of estrogen. Cell Signal. 24, 1847-1855 (2012).
-
(2012)
Cell Signal.
, vol.24
, pp. 1847-1855
-
-
Eastman, B.M.1
Jo, M.2
Webb, D.L.3
Takimoto, S.4
Gonias, S.L.5
-
23
-
-
84887102623
-
Glioblastoma and other malignant gliomas, a clinical review
-
Omuro, A. & DeAngelis, L. M. Glioblastoma and other malignant gliomas, a clinical review. JAMA. 310, 1842-1850 (2013).
-
(2013)
JAMA.
, vol.310
, pp. 1842-1850
-
-
Omuro, A.1
DeAngelis, L.M.2
-
24
-
-
35949002429
-
Malignant astrocytic glioma, genetics, biology, and paths to treatment
-
Furnari, F. B. et al. Malignant astrocytic glioma, genetics, biology, and paths to treatment. Genes Dev. 21, 2683-2710 (2007).
-
(2007)
Genes Dev.
, vol.21
, pp. 2683-2710
-
-
Furnari, F.B.1
-
25
-
-
54549108740
-
Comprehensive genomic characterization defines human glioblastoma genes and core pathways
-
The Cancer Genome Atlas Research Network.
-
The Cancer Genome Atlas Research Network. Comprehensive genomic characterization defines human glioblastoma genes and core pathways. Nature. 455, 1061-1068 (2008).
-
(2008)
Nature.
, vol.455
, pp. 1061-1068
-
-
-
26
-
-
84859847164
-
Emerging insights into the molecular and cellular basis of glioblastoma
-
Dunn, G. P. et al. Emerging insights into the molecular and cellular basis of glioblastoma. Genes Dev. 26, 756-784 (2012).
-
(2012)
Genes Dev.
, vol.26
, pp. 756-784
-
-
Dunn, G.P.1
-
27
-
-
84885074034
-
The somatic genomic landscape of glioblastoma
-
Brennan, C. W. et al. The somatic genomic landscape of glioblastoma. Cell. 155, 462-477 (2013).
-
(2013)
Cell.
, vol.155
, pp. 462-477
-
-
Brennan, C.W.1
-
28
-
-
73649123907
-
Integrated genomic analysis identifies clinically relevant subtypes of glioblastoma characterized by abnormalities in PDGFRA, IDH1, EGFR, and NF1
-
Verhaak, R. G. et al. Integrated genomic analysis identifies clinically relevant subtypes of glioblastoma characterized by abnormalities in PDGFRA, IDH1, EGFR, and NF1. Cancer Cell. 17, 98-110 (2010).
-
(2010)
Cancer Cell.
, vol.17
, pp. 98-110
-
-
Verhaak, R.G.1
-
29
-
-
33644820339
-
Molecular subclasses of high-grade glioma predict prognosis, delineate a pattern of disease progression, and resemble stages in neurogenesis
-
Phillips, H. S. et al. Molecular subclasses of high-grade glioma predict prognosis, delineate a pattern of disease progression, and resemble stages in neurogenesis. Cancer Cell. 9, 157-173 (2006).
-
(2006)
Cancer Cell.
, vol.9
, pp. 157-173
-
-
Phillips, H.S.1
-
30
-
-
84908406981
-
Brain tumor cells in circulation are enriched for mesenchymal gene expression
-
Sullivan, J. P. et al. Brain tumor cells in circulation are enriched for mesenchymal gene expression. Cancer Discov. 4, 1299-1309 (2014).
-
(2014)
Cancer Discov.
, vol.4
, pp. 1299-1309
-
-
Sullivan, J.P.1
-
31
-
-
84902668801
-
Single-cell RNA-seq highlights intratumoral heterogeneity in primary glioblastoma
-
Patel, A. P. et al. Single-cell RNA-seq highlights intratumoral heterogeneity in primary glioblastoma. Science. 344, 1396-1401 (2014).
-
(2014)
Science.
, vol.344
, pp. 1396-1401
-
-
Patel, A.P.1
-
32
-
-
80053135166
-
Crosstalk between the urokinase-type plasminogen activator receptor and EGF receptor variant III supports survival and growth of glioblastoma cells
-
Hu, J. et al. Crosstalk between the urokinase-type plasminogen activator receptor and EGF receptor variant III supports survival and growth of glioblastoma cells. Proc Natl Acad Sci USA 108, 15984-15989 (2011).
-
(2011)
Proc Natl Acad Sci USA
, vol.108
, pp. 15984-15989
-
-
Hu, J.1
-
33
-
-
84940086231
-
Neutralizing the EGF receptor in glioblastoma cells stimulates cell migration by activating uPAR-initiated cell signaling
-
Hu, J. et al. Neutralizing the EGF receptor in glioblastoma cells stimulates cell migration by activating uPAR-initiated cell signaling. Oncogene. 34, 1-11 (2014).
-
(2014)
Oncogene.
, vol.34
, pp. 1-11
-
-
Hu, J.1
-
34
-
-
84920996740
-
A urokinase receptor-Bim signaling axis emerges during EGFR inhibitor resistance in mutant EGFR glioblastoma
-
Wykosky, J. et al. A urokinase receptor-Bim signaling axis emerges during EGFR inhibitor resistance in mutant EGFR glioblastoma. Cancer Res. 75, 394-404 (2015).
-
(2015)
Cancer Res.
, vol.75
, pp. 394-404
-
-
Wykosky, J.1
-
35
-
-
42949149114
-
Glioblastoma-derived stem cell-enriched cultures form distinct subgroups according to molecular and phenotypic criteria
-
Gunther, H. S. et al. Glioblastoma-derived stem cell-enriched cultures form distinct subgroups according to molecular and phenotypic criteria. Oncogene. 27, 2897-2909 (2008).
-
(2008)
Oncogene.
, vol.27
, pp. 2897-2909
-
-
Gunther, H.S.1
-
36
-
-
65749087298
-
Neurosphere formation is an independent predictor of clinical outcome in malignant glioma
-
Laks, D. R. et al. Neurosphere formation is an independent predictor of clinical outcome in malignant glioma. Stem Cells. 27, 980-987 (2009).
-
(2009)
Stem Cells.
, vol.27
, pp. 980-987
-
-
Laks, D.R.1
-
37
-
-
77950502115
-
A hierarchy of self-renewing tumor-initiating cell types in glioblastoma
-
Chen, R. et al. A hierarchy of self-renewing tumor-initiating cell types in glioblastoma. Cancer Cell. 17, 362-375 (2010).
-
(2010)
Cancer Cell.
, vol.17
, pp. 362-375
-
-
Chen, R.1
-
38
-
-
0028026686
-
Expression and localization of urokinase-type plasminogen activator in human astrocytomas in vivo
-
Yamamoto, M. et al. Expression and localization of urokinase-type plasminogen activator in human astrocytomas in vivo. Cancer Res. 54, 3656-3661 (1994).
-
(1994)
Cancer Res.
, vol.54
, pp. 3656-3661
-
-
Yamamoto, M.1
-
39
-
-
19444385685
-
Expression of urokinase-type plasminogen activator receptor (uPAR) in primary central nervous system neoplasms
-
Salajegheh, M., Rudnicki, A. & Smith, T. W. Expression of urokinase-type plasminogen activator receptor (uPAR) in primary central nervous system neoplasms. Appl Immunohistochem Mol Morphol. 13, 184-189 (2005).
-
(2005)
Appl Immunohistochem Mol Morphol.
, vol.13
, pp. 184-189
-
-
Salajegheh, M.1
Rudnicki, A.2
Smith, T.W.3
-
40
-
-
84955561447
-
Molecular profiling reveals biologically discrete subsets and pathways of progression in diffuse glioma
-
Ceccarelli, M. et al. Molecular Profiling Reveals Biologically Discrete Subsets and Pathways of Progression in Diffuse Glioma. Cell. 164, 550-563 (2016).
-
(2016)
Cell.
, vol.164
, pp. 550-563
-
-
Ceccarelli, M.1
-
41
-
-
57749195712
-
RNA-Seq, a revolutionary tool for transcriptomics
-
Wang, Z., Gerstein, M. & Snyder, M. RNA-Seq, a revolutionary tool for transcriptomics. Nat Rev Genet. 10, 57-63 (2009).
-
(2009)
Nat Rev Genet.
, vol.10
, pp. 57-63
-
-
Wang, Z.1
Gerstein, M.2
Snyder, M.3
-
42
-
-
77952108366
-
Identification of a CpG island methylator phenotype that defines a distinct subgroup of glioma
-
Noushmehr, H. et al. Identification of a CpG island methylator phenotype that defines a distinct subgroup of glioma. Cancer Cell. 17, 510-522 (2010).
-
(2010)
Cancer Cell.
, vol.17
, pp. 510-522
-
-
Noushmehr, H.1
-
43
-
-
84858796263
-
IDH1 mutation is sufficient to establish the glioma hypermethylator phenotype
-
Turcan, S. et al. IDH1 mutation is sufficient to establish the glioma hypermethylator phenotype. Nature. 483, 479-483 (2012).
-
(2012)
Nature.
, vol.483
, pp. 479-483
-
-
Turcan, S.1
-
44
-
-
4944250781
-
Isolation and characterization of tumorigenic, stem-like neural precursors from human glioblastoma
-
Galli, R. et al. Isolation and characterization of tumorigenic, stem-like neural precursors from human glioblastoma. Cancer Res. 64, 7011-7021 (2004).
-
(2004)
Cancer Res.
, vol.64
, pp. 7011-7021
-
-
Galli, R.1
-
45
-
-
84964693878
-
Spherical cancer models in tumor biology
-
Weiswald, L. B., Bellet, D. & Dangles-Marie, V. Spherical cancer models in tumor biology. Neoplasia 17, 1-15 (2015).
-
(2015)
Neoplasia
, vol.17
, pp. 1-15
-
-
Weiswald, L.B.1
Bellet, D.2
Dangles-Marie, V.3
-
46
-
-
84878151308
-
Mesenchymal glioma stem cells are maintained by activated glycolytic metabolism involving aldehyde dehydrogenase 1A3
-
Mao, P. et al. Mesenchymal glioma stem cells are maintained by activated glycolytic metabolism involving aldehyde dehydrogenase 1A3. Proc Natl Acad Sci USA 110, 8644-8649 (2013).
-
(2013)
Proc Natl Acad Sci USA
, vol.110
, pp. 8644-8649
-
-
Mao, P.1
-
47
-
-
84925612958
-
Coexpression analysis of CD133 and CD44 identifies proneural and mesenchymal subtypes of glioblastoma multiforme
-
Brown, D. V. et al. Coexpression analysis of CD133 and CD44 identifies proneural and mesenchymal subtypes of glioblastoma multiforme. Oncotarget. 6, 6267-6280 (2015).
-
(2015)
Oncotarget.
, vol.6
, pp. 6267-6280
-
-
Brown, D.V.1
-
48
-
-
77950221879
-
Transcriptional profiles of CD133+ and CD133? Glioblastoma-derived cancer stem cell lines suggest different cells of origin
-
Lottaz, C. et al. Transcriptional profiles of CD133+ and CD133? glioblastoma-derived cancer stem cell lines suggest different cells of origin. Cancer Res. 70, 2030-2040 (2010).
-
(2010)
Cancer Res.
, vol.70
, pp. 2030-2040
-
-
Lottaz, C.1
-
49
-
-
43649086456
-
Isolation and characterization of cancer stem cells from a human glioblastoma cell line U87
-
Yu, S. C. et al. Isolation and characterization of cancer stem cells from a human glioblastoma cell line U87. Cancer Lett. 265, 124-134 (2008).
-
(2008)
Cancer Lett.
, vol.265
, pp. 124-134
-
-
Yu, S.C.1
-
50
-
-
14644412873
-
Prognostic effect of epidermal growth factor receptor and EGFRvIII in glioblastoma multiforme patients
-
Heimberger, A. B. et al. Prognostic effect of epidermal growth factor receptor and EGFRvIII in glioblastoma multiforme patients. Clin Cancer Res. 11, 1462-1466 (2005).
-
(2005)
Clin Cancer Res.
, vol.11
, pp. 1462-1466
-
-
Heimberger, A.B.1
-
51
-
-
0025114687
-
Identical splicing of aberrant epidermal growth factor receptor transcripts from amplified rearranged genes in human glioblastomas
-
Sugawa, N., Ekstrand, A. J., James, C. D. & Collins, V. P. Identical splicing of aberrant epidermal growth factor receptor transcripts from amplified rearranged genes in human glioblastomas. Proc Natl Acad Sci USA 87, 8602-8606 (1990).
-
(1990)
Proc Natl Acad Sci USA
, vol.87
, pp. 8602-8606
-
-
Sugawa, N.1
Ekstrand, A.J.2
James, C.D.3
Collins, V.P.4
-
52
-
-
0028146767
-
A mutant epidermal growth factor receptor common in human glioma confers enhanced tumorigenicity
-
Nishikawa, R. et al. A mutant epidermal growth factor receptor common in human glioma confers enhanced tumorigenicity. Proc Natl Acad Sci USA 91, 7727-7731 (1994).
-
(1994)
Proc Natl Acad Sci USA
, vol.91
, pp. 7727-7731
-
-
Nishikawa, R.1
-
53
-
-
85006325096
-
Pertussis toxin is a robust and selective inhibitor of high grade glioma cell migration and invasion
-
Gilder, A. S. et al. Pertussis Toxin Is a Robust and Selective Inhibitor of High Grade Glioma Cell Migration and Invasion. PLoS One. 11, e0168418 (2016).
-
(2016)
PLoS One.
, vol.11
, pp. e0168418
-
-
Gilder, A.S.1
-
54
-
-
53249122047
-
Urokinase plasminogen activator receptor choreographs multiple ligand interactions, implications for tumor progression and therapy
-
Mazar, A. P. Urokinase plasminogen activator receptor choreographs multiple ligand interactions, implications for tumor progression and therapy. Clin Cancer Res. 14, 5649-5655 (2008).
-
(2008)
Clin Cancer Res.
, vol.14
, pp. 5649-5655
-
-
Mazar, A.P.1
-
55
-
-
84940040997
-
Urokinase receptor and resistance to targeted anticancer agents
-
Gonias, S. L. & Hu, J. Urokinase receptor and resistance to targeted anticancer agents. Front Pharmacol 6, 154 (2015).
-
(2015)
Front Pharmacol
, vol.6
, pp. 154
-
-
Gonias, S.L.1
Hu, J.2
-
56
-
-
0035147370
-
The murine receptor for urokinase-type plasminogen activator is primarily expressed in tissues actively undergoing remodeling
-
Solberg, H., Ploug, M., Hoyer-Hansen, G., Nielsen, B. S. & Lund, L. R. The murine receptor for urokinase-type plasminogen activator is primarily expressed in tissues actively undergoing remodeling. J Histochem Cytochem. 49, 237-246 (2001).
-
(2001)
J Histochem Cytochem.
, vol.49
, pp. 237-246
-
-
Solberg, H.1
Ploug, M.2
Hoyer-Hansen, G.3
Nielsen, B.S.4
Lund, L.R.5
-
57
-
-
85042086812
-
Urokinase-type plasminogen activator (uPA) and its receptor (uPAR) promote neurorepair in the ischemic brain
-
Merino, P., Diaz, A. & Yepes, M. Urokinase-type plasminogen activator (uPA) and its receptor (uPAR) promote neurorepair in the ischemic brain. Receptors Clin Investig. 4, e1552 (2017).
-
(2017)
Receptors Clin Investig.
, vol.4
, pp. e1552
-
-
Merino, P.1
Diaz, A.2
Yepes, M.3
-
58
-
-
0032079312
-
Hypoxia stimulates urokinase receptor expression through a heme proteindependent pathway
-
Graham, C. H., Fitzpatrick, T. E. & McCrae, K. R. Hypoxia stimulates urokinase receptor expression through a heme proteindependent pathway. Blood. 91, 3300-3307 (1998).
-
(1998)
Blood.
, vol.91
, pp. 3300-3307
-
-
Graham, C.H.1
Fitzpatrick, T.E.2
McCrae, K.R.3
-
59
-
-
0029067419
-
The receptor for urokinase-type plasminogen activator is not essential for mouse development or fertility
-
Bugge, T. H. et al. The receptor for urokinase-type plasminogen activator is not essential for mouse development or fertility. J Biol Chem. 270, 16886-16894 (1995).
-
(1995)
J Biol Chem.
, vol.270
, pp. 16886-16894
-
-
Bugge, T.H.1
-
60
-
-
16844386886
-
Plasminogen activation and cancer
-
Dano, K. et al. Plasminogen activation and cancer. Thromb Haemost. 93, 676-681 (2005).
-
(2005)
Thromb Haemost.
, vol.93
, pp. 676-681
-
-
Dano, K.1
-
62
-
-
77955911497
-
Tumor heterogeneity is an active process maintained by a mutant EGFR-induced cytokine circuit in glioblastoma
-
Inda, M. M. et al. Tumor heterogeneity is an active process maintained by a mutant EGFR-induced cytokine circuit in glioblastoma. Genes Dev. 24, 1731-1745 (2010).
-
(2010)
Genes Dev.
, vol.24
, pp. 1731-1745
-
-
Inda, M.M.1
-
63
-
-
85027005612
-
Glioblastoma cellular cross-talk converges on NF-kappaB to attenuate EGFR inhibitor sensitivity
-
Zanca, C. et al. Glioblastoma cellular cross-talk converges on NF-kappaB to attenuate EGFR inhibitor sensitivity. Genes Dev. https:// doi. org/10. 1101/gad. 300079. 117 (2017).
-
(2017)
Genes Dev.
-
-
Zanca, C.1
-
64
-
-
84931291979
-
Soluble urokinase receptor is released selectively by glioblastoma cells that express epidermal growth factor receptor variant III and promotes tumor cell migration and invasion
-
Gilder, A. S. et al. Soluble urokinase receptor is released selectively by glioblastoma cells that express epidermal growth factor receptor variant III and promotes tumor cell migration and invasion. J Biol Chem. 290, 14798-14809 (2015).
-
(2015)
J Biol Chem.
, vol.290
, pp. 14798-14809
-
-
Gilder, A.S.1
-
65
-
-
0037449805
-
Epidermal growth factor receptor-dependent and-independent cellsignaling pathways originating from the urokinase receptor
-
Jo, M., Thomas, K. S., O'Donnell, D. M. & Gonias, S. L. Epidermal growth factor receptor-dependent and-independent cellsignaling pathways originating from the urokinase receptor. J Biol Chem. 278, 1642-1646 (2003).
-
(2003)
J Biol Chem.
, vol.278
, pp. 1642-1646
-
-
Jo, M.1
Thomas, K.S.2
O'Donnell, D.M.3
Gonias, S.L.4
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