Dynamic assembly of the urokinase-type plasminogen activator signaling receptor complex determines the mitogenic activity of urokinase-type plasminogen activator

Journal of Biological Chemistry

Volumn 280, Issue 17, 2005, Pages 17449-17457

  Jo, Minji ^a   Thomas, Keena S ^b   Marozkina, Nadzeya ^c   Amin, Tanay J ^b   Silva, Corinne M ^b,c   Parsons, Sarah J ^c   Gonias, Steven L ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b UNIVERSITY OF VIRGINIA   (United States)

^c UNIVERSITY OF VIRGINIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BIOCHEMISTRY; CELL CULTURE; CELLS; MOLECULAR BIOLOGY; PROTEINS;

CO-RECEPTORS; EPIDERMAL GROWTH; EPIDERMAL GROWTH FACTOR RECEPTOR (EGFR);

SIGNALING;

CELL RECEPTOR; CORECEPTOR; EPIDERMAL GROWTH FACTOR RECEPTOR; FORMYLPEPTIDE RECEPTOR; FORMYLPEPTIDE RECEPTOR LIKE RECEPTOR; INTEGRIN; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE 1; MUTANT PROTEIN; PERTUSSIS TOXIN; PLASMINOGEN ACTIVATOR INHIBITOR 1; STAT5B PROTEIN; TYROSINE; UNCLASSIFIED DRUG; UROKINASE; UROKINASE RECEPTOR; BROXURIDINE; COLORING AGENT; DNA; DNA BINDING PROTEIN; GREEN FLUORESCENT PROTEIN; MILK PROTEIN; PROTEIN TYROSINE KINASE; SMALL INTERFERING RNA; STAT5 PROTEIN; STAT5B PROTEIN, HUMAN; TETRAZOLIUM; THIAZOLE DERIVATIVE; THIAZOLYL BLUE; TRANSACTIVATOR PROTEIN;

ANIMAL CELL; ARTICLE; BREAST CANCER; CANCER CELL CULTURE; CANCER GROWTH; CELL PROLIFERATION; CELL STRAIN; CELL STRAIN MCF 7; CELL STRAIN MDA MB 488; CHO CELL; CHO K1 CELL; COMPLEX FORMATION; CONTROLLED STUDY; ENZYME ACTIVATION; HUMAN; HUMAN CELL; KINETICS; MITOGENESIS; NONHUMAN; PRIORITY JOURNAL; PROTEIN ASSEMBLY; PROTEIN PHOSPHORYLATION; RECEPTOR BINDING; ANIMAL; GENETIC TRANSFECTION; HAMSTER; IMMUNOPRECIPITATION; METABOLISM; MUTATION; PHOSPHORYLATION; PROGNOSIS; PROTEIN BINDING; SIGNAL TRANSDUCTION; TIME; TUMOR CELL LINE;

CRICETULUS GRISEUS; MINK CELL FOCUS-FORMING VIRUS;

ANIMALS; BROMODEOXYURIDINE; CELL LINE, TUMOR; CELL PROLIFERATION; CHO CELLS; COLORING AGENTS; CRICETINAE; DNA; DNA-BINDING PROTEINS; ENZYME ACTIVATION; EXTRACELLULAR SIGNAL-REGULATED MAP KINASES; GREEN FLUORESCENT PROTEINS; HUMANS; IMMUNOPRECIPITATION; KINETICS; MILK PROTEINS; MUTATION; PERTUSSIS TOXIN; PHOSPHORYLATION; PROGNOSIS; PROTEIN BINDING; RECEPTOR, EPIDERMAL GROWTH FACTOR; RNA, SMALL INTERFERING; SIGNAL TRANSDUCTION; SRC-FAMILY KINASES; STAT5 TRANSCRIPTION FACTOR; TETRAZOLIUM SALTS; THIAZOLES; TIME FACTORS; TRANS-ACTIVATORS; TRANSFECTION; TYROSINE; URINARY PLASMINOGEN ACTIVATOR;

EID: 20444478292     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M413141200     Document Type: Article

References (53)

1. Yamauchi, T., Ueki, K., Tobe, K., Tamemoto, H., Sekine, N., Wada, M., Honjo, M., Takahashi, M., Takahashi, T., Hirai, H., Tushima, T., Akanuma, Y., Fujita, T., Komuro, I., Yazaki, Y., and Kadowaki, T. (1997) Nature 390, 91-96
2. Daub, H., Weiss, F. U., Wallasch, C., and Ullrich, A. (1996) Nature 379, 557-560
3. Moro, L., Venturino, M., Bozzo, C., Silengo, L., Altruda, F., Beguinot, L., Tarone, G., and Defilippi, P. (1998) EMBO J. 17, 6622-6632
4. Prenzel, N., Zwick, E., Daub, H., Leserer, M., Abraham, R., Wallasch, C., and Ullrich, A. (1999) Nature 402, 884-888
5. Yan, Y., Shirakabe, K., and Werb, Z. (2002) J. Cell Biol. 158, 221-226
6. Luttrell, L. M., Della Rocca, G. J., van Biesen, T., Luttrell, D. K., and Lefkowitz, R. J. (1997) J. Biol. Chem. 272, 4637-4644
7. Wei, Y., Lukashev, M., Simon, D. I., Bodary, S. C., Rosenberg, S., Doyle, M. V., and Chapman, H. A. (1996) Science 273, 1551-1555
8. Kjoller, L., and Hall, A. (2001) J. Cell Biol. 152, 1145-1157
9. Ma, Z., Thomas, K. S., Webb, D. J., Moravec, R., Salicioni, A. M., Mars, W. M., and Gonias, S. L. (2002) J. Cell Biol. 159, 1061-1070
10. Nguyen, D. H., Hussaini, I. M., and Gonias, S. L. (1998) J. Biol. Chem. 273, 8502-8507
11. Nguyen, D. H., Catling, A. D., Webb, D. J., Sankovic, M., Walker, L. A., Somlyo, A. V., Weber, M. J., and Gonias, S. L. (1999) J. Cell Biol. 146, 149-164
12. Tang, H., Kerins, D. M., Hao, Q., Inagami, T., and Vaughan, D. E. (1998) J. Biol. Chem. 273, 18268-18272
13. Aguirre Ghiso, J. A., Kovalski, K., and Ossowski, L. (1999) J. Cell Biol. 147, 89-104
14. Ma, Z., Webb, D. J., Jo, M., and Gonias, S. L. (2001) J. Cell Sci. 114, 3387-3396
15. Nguyen, D. H., Webb, D. J., Catling, A. D., Song, Q., Dhakephalkar, A., Weber, M. J., Ravichandran, K. S., and Gonias, S. L. (2000) J. Biol. Chem. 275, 19382-19388
16. Fazioli, F., Resnati, M., Sidenius, N., Higashimoto, Y., Appella, E., and Blasi, F. (1997) EMBO J. 16, 7279-7286
17. Degryse, B., Resnati, M., Rabbani, S. A., Villa, A., Fazioli, F., and Blasi, F. (1999) Blood 94, 649-662
18. Jo, M., Thomas, K. S., Wu, L., and Gonias, S. L. (2003) J. Biol. Chem. 278, 46692-46698
19. Resnati, M., Pallavicini, I., Wang, J. M., Oppenheim, J., Serhan, C. N., Romano, M., and Blasi, F. (2002) Proc. Natl. Acad. Sci. U. S. A. 99, 1359-1364
20. Liu, D., Aguirre Ghiso, J., Estrada, Y., and Ossowski, L. (2002) Cancer Cell 1, 445-457
21. Yebra, M., Parry, G. C., Stromblad, S., Mackman, N., Rosenberg, S., Mueller, B. M., and Cheresh, D. A. (1996) J. Biol. Chem. 271, 29393-29399
22. Bolla, M., Chedin, M., Souvignet, C., Marron, J., Arnould, C., and Chambaz, E. (1990) Breast Cancer Res. Treat. 16, 97-102
23. Toi, M., Osaki, A., Yamada, H., and Toge, T. (1991) Eur. J. Cancer 27, 977-980
24. Andreasen, P. A., Kjoller, L., Christensen, L., and Duffy, M. J. (1997) Int. J. Cancer 72, 1-22
25. Duffy, M. J., Maguire, T. M., McDermott, E. W., and O'Higgins, N. (1999) J. Surg. Oncol. 71, 130-135
26. Jo, M., Thomas, K. S., O'Donnell, D. M., and Gonias, S. L. (2003) J. Biol. Chem. 278, 1642-1646
27. Guerrero, J., Santibanez, J. F., Gonzalez, A., and Martinez, J. (2004) Exp. Cell Res. 292, 201-208
28. Kloth, M. T., Laughlin, K. K., Biscardi, J. S., Boerner, J. L., Parsons, S. J., and Silva, C. M. (2003) J. Biol. Chem. 278, 1671-1679
29. Chen, W. S., Lazar, C. S., Poenie, M., Tsien, R. Y., Gill, G. N., and Rosenfeld, M. G. (1987) Nature 328, 820-823
30. Biscardi, J. S., Maa, M. C., Tice, D. A., Cox, M. E., Leu, T. H., and Parsons, S. J. (1999) J. Biol. Chem. 274, 8335-8343
31. Moriggl, R., Gouilleux-Gruart, V., Jahne, R., Berchtold, S., Gartmann, C., Liu, X., Hennighausen, L., Sotiropoulos, A., Groner, B., and Gouilleux, F. (1996) Mol. Cell. Biol. 16, 5691-5700
32. Carmichael, J., DeGraff, W. G., Gazdar, A. F., Minna, J. D., and Mitchell, J. B. (1987) Cancer Res. 47, 943-946
33. Weber, J. D., Raben, D. M., Phillips, P. J., and Baldassare, J. J. (1997) Biochem. J. 326, 61-68
34. Balmanno, K., and Cook, S. J. (1999) Oncogene 18, 3085-3097
35. Murphy, L. O., Smith, S., Chen, R. H., Fingar, D. C., and Blenis, J. (2002) Nat. Cell Biol. 4, 556-564
36. Kahan, C., Seuwen, K., Meloche, S., and Pouyssegur, J. (1992) J. Biol. Chem. 267, 13369-13375
37. Maa, M. C., Leu, T. H., McCarley, D. J., Schatzman, R. C., and Parsons, S. J. (1995) Proc. Natl. Acad. Sci. U. S. A. 92, 6981-6985
38. Peschon, J. J., Slack, J. L., Reddy, P., Stocking, K. L., Sunnarborg, S. W., Lee, D. C., Russell, W. E., Castner, B. J., Johnson, R. S., Fitzner, J. N., Boyce, R. W., Nelson, N., Kozlosky, C. J., Wolfson, M. F., Rauch, C. T., Cerretti, D. P., Paxton, R. J., March, C. J., and Black, R. A. (1998) Science 282, 1281-1284
39. Webb, D. J., Thomas, K. S., and Gonias, S. L. (2001) J. Cell Biol. 152, 741-752
40. Sibilia, M., and Wagner, E. F. (1995) Science 269, 234-238
41. Threadgill, D. W., Dlugosz, A. A., Hansen, L. A., Tennenbaum, T., Lichti, U., Yee, D., LaMantia, C., Mourton, T., Herrup, K., Harris, R. C., Barnard, J. A., Yuspa, S. H., Coffey, R. J., and Magnuson, T. (1995) Science 269, 230-234
42. Khazaie, K., Schirrmacher, V., and Lichtner, R. B. (1993) Cancer Metastasis Rev. 12, 255-274
43. Prenzel, N., Zwick, E., Leserer, M., and Ullrich, A. (2000) Breast Cancer Res. 2, 184-190
44. Knoop, A., Andreasen, P. A., Andersen, J. A., Hansen, S., Laenkholm, A. V., Simonsen, A. C., Andersen, J., Overgaard, J., and Rose, C. (1998) Br. J. Cancer 77, 932-940
45. Bajou, K., Noel, A., Gerard, R. D., Masson, V., Brunner, N., Holst-Hansen, C., Skobe, M., Fusenig, N. E., Carmeliet, P., Collen, D., and Foidart, J. M. (1998) Nat. Med. 4, 923-928
46. Aguirre-Ghiso, J. A., Estrada, Y., Liu, D., and Ossowski, L. (2003) Cancer Res. 63, 1684-1695
47. Aguirre-Ghiso, J. A., Liu, D., Mignatti, A., Kovalski, K., and Ossowski, L. (2001) Mol. Biol. Cell 12, 863-879
48. Fan, H., and Derynck, R. (1999) EMBO J. 18, 6962-6972
49. Gechtman, Z., Alonso, J. L., Raab, G., Ingber, D. E., and Klagsbrun, M. (1999) J. Biol. Chem. 274, 28828-28835
50. Bringman, T. S., Lindquist, P. B., and Derynck, R. (1987) Cell 48, 429-440
51. Tzahar, E., Waterman, H., Chen, X., Levkowitz, G., Karunagaran, D., Lavi, S., Ratzkin, B. J., and Yarden, Y. (1996) Mol. Cell. Biol. 16, 5276-5287
52. Xu, X., Kelleher, K. F., Liao, J., Creek, K. E., and Pirisi, L. (2000) Oncogene 19, 3172-3181
53. Pierce, K. L., Tohgo, A., Ahn, S., Field, M. E., Luttrell, L. M., and Lefkowitz, R. J. (2001) J. Biol. Chem. 276, 23155-23160