Nicotine promotes atherosclerosis via ROS-NLRP3-mediated endothelial cell pyroptosis

Cell Death and Disease

Volumn 9, Issue 2, 2018, Pages

  Wu, Xianxian ^a,b   Zhang, Haiying ^a   Qi, Wei ^a   Zhang, Ying ^a   Li, Jiamin ^a   Li, Zhange ^a   Lin, Yuan ^a   Bai, Xue ^a   Liu, Xin ^a   Chen, Xiaohui ^a   Yang, Huan ^a   Xu, Chaoqian ^a   Zhang, Yong ^a,c   Yang, Baofeng ^a,d  

^a HARBIN MEDICAL UNIVERSITY   (China)

^b INSTITUTE OF LABORATORY ANIMAL SCIENCE   (China)

^c Biopharmaceutical Institute   (China)

^d UNIVERSITY OF MELBOURNE   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

CRYOPYRIN; INTERLEUKIN 18; INTERLEUKIN 1BETA; INTERLEUKIN 1BETA CONVERTING ENZYME; NICOTINE; REACTIVE OXYGEN METABOLITE; SMALL INTERFERING RNA; APOLIPOPROTEIN E; CASPASE INHIBITOR; CASPASE RECRUITMENT DOMAIN SIGNALING PROTEIN; INFLAMMASOME; PYCARD PROTEIN, HUMAN;

ANIMAL EXPERIMENT; ANIMAL MODEL; AORTIC ENDOTHELIAL CELL; ARTICLE; ATHEROSCLEROSIS; CELL MATURATION; CONFOCAL LASER SCANNING MICROSCOPY; CONTROLLED STUDY; GENE EXPRESSION; HUMAN; HUMAN CELL; IMMUNOHISTOCHEMISTRY; INTIMA; MOUSE; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; PYROPTOSIS; REAL TIME POLYMERASE CHAIN REACTION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; ANIMAL; AORTA; BIOLOGICAL MODEL; DEFICIENCY; DRUG EFFECT; ENDOTHELIUM CELL; METABOLISM; PATHOLOGY;

ANIMALS; AORTA; APOLIPOPROTEINS E; ATHEROSCLEROSIS; CARD SIGNALING ADAPTOR PROTEINS; CASPASE 1; CASPASE INHIBITORS; ENDOTHELIAL CELLS; HUMANS; INFLAMMASOMES; INTERLEUKIN-18; INTERLEUKIN-1BETA; MICE; MODELS, BIOLOGICAL; NICOTINE; NLR FAMILY, PYRIN DOMAIN-CONTAINING 3 PROTEIN; PYROPTOSIS; REACTIVE OXYGEN SPECIES;

EID: 85041693664     PISSN: None     EISSN: 20414889     Source Type: Journal    
DOI: 10.1038/s41419-017-0257-3     Document Type: Article

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