Oxidized LDL attenuates protective autophagy and induces apoptotic cell death of endothelial cells: Role of oxidative stress and LOX-1 receptor expression

International Journal of Cardiology

Volumn 184, Issue 1, 2015, Pages 152-158

  Mollace, Vincenzo ^a,c   Gliozzi, Micaela ^a   Musolino, Vincenzo ^a   Carresi, Cristina ^a   Muscoli, Saverio ^b   Mollace, Rocco ^a   Tavernese, Annamaria ^a   Gratteri, Santo ^a   Palma, Ernesto ^a   Morabito, Chiara ^a   Vitale, Cristiana ^c   Muscoli, Carolina ^a,c   Fini, Massimo ^c   Romeo, Francesco ^b  

^a Department of Pharmacobiological Sciences   (Italy)

^b UNIVERSITY OF ROME TOR VERGATA   (Italy)

^c IRCCS SAN RAFFAELE PISANA   (Italy)

Author keywords

LOX 1; Oxidative stress; Oxidized LDL; Protective autophagy

Indexed keywords

ACETYLCYSTEINE; BECLIN 1; BIOLOGICAL MARKER; ENDOTHELIAL NITRIC OXIDE SYNTHASE; MALONALDEHYDE; MICROTUBULE ASSOCIATED PROTEIN 1A 1B LIGHT CHAIN 3; OXIDIZED LOW DENSITY LIPOPROTEIN; OXIDIZED LOW DENSITY LIPOPROTEIN RECEPTOR 1; SHORT HAIRPIN RNA; UNCLASSIFIED DRUG; VASCULOTROPIN; LOW DENSITY LIPOPROTEIN; OLR1 PROTEIN, HUMAN;

AORTA ENDOTHELIUM; APOPTOSIS; ARTICLE; AUTOPHAGY; BOVINE; CELL VIABILITY; ENDOTHELIUM CELL; ENZYME PHOSPHORYLATION; FLOW CYTOMETRY; FLUORESCENCE ACTIVATED CELL SORTING; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN EXPRESSION; WESTERN BLOTTING; ANIMAL; BIOSYNTHESIS; CELL CULTURE; CELL DEATH; DOSE RESPONSE; DRUG EFFECTS; GENE EXPRESSION REGULATION; METABOLISM; PHYSIOLOGY;

ANIMALS; APOPTOSIS; AUTOPHAGY; CATTLE; CELL DEATH; CELLS, CULTURED; DOSE-RESPONSE RELATIONSHIP, DRUG; ENDOTHELIAL CELLS; GENE EXPRESSION REGULATION; LIPOPROTEINS, LDL; OXIDATIVE STRESS; SCAVENGER RECEPTORS, CLASS E;

EID: 84933519314     PISSN: 01675273     EISSN: 18741754     Source Type: Journal    
DOI: 10.1016/j.ijcard.2015.02.007     Document Type: Article

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