Nicotine accelerates atherosclerosis in Apolipoprotein E-deficient mice by activating α7 nicotinic acetylcholine receptor on mast cells

Arteriosclerosis, Thrombosis, and Vascular Biology

Volumn 37, Issue 1, 2017, Pages 53-65

  Wang, Chen ^a,b   Chen, Han ^a,b   Zhu, Wei ^a,b   Xu, Yinchuan ^a,b   Liu, Mingfei ^b   Zhu, Lianlian ^a,b   Yang, Fan ^b   Zhang, Ling ^a,b   Liu, Xianbao ^a,b   Zhong, Zhiwei ^a,b   Zhao, Jing ^a,b   Jiang, Jun ^a,b   Xiang, Meixiang ^a,b   Yu, Hong ^a,b   Hu, Xinyang ^a,b   Lu, Hong ^c   Wang, Jian'an ^a,b  

^a ZHEJIANG UNIVERSITY   (China)

^b Provincial Key Laboratory of Cardiovascular Research of Zhejiang Province   (China)

^c UNIVERSITY OF KENTUCKY   (United States)

Author keywords

apolipoprotein E; atherosclerosis; hypercholesterolemia; mast cell; nicotine

Indexed keywords

APOLIPOPROTEIN E; BUNGAROTOXIN RECEPTOR; COLLAGEN; MECAMYLAMINE; NICOTINE; CHOLESTEROL; CHRNA7 PROTEIN, MOUSE; NICOTINIC AGENT; NICOTINIC RECEPTOR BLOCKING AGENT; STEM CELL FACTOR RECEPTOR;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; ATHEROSCLEROSIS; ATHEROSCLEROTIC PLAQUE; IN VITRO STUDY; LIPID STORAGE; MACROPHAGE; MAST CELL; MOUSE; NONHUMAN; PRIORITY JOURNAL; SMOOTH MUSCLE CELL; AGONISTS; ANIMAL; AORTIC DISEASES; BONE MARROW TRANSPLANTATION; CELL CULTURE; CHEMICALLY INDUCED; DEFICIENCY; DEGRANULATION; DISEASE COURSE; DISEASE MODEL; DRUG EFFECTS; FOAM CELL; GENETIC PREDISPOSITION; GENETICS; KNOCKOUT MOUSE; LIPID DIET; MALE; METABOLISM; PATHOLOGY; PERITONEUM MACROPHAGE; PHENOTYPE; SIGNAL TRANSDUCTION; THORACIC AORTA; TIME FACTOR; VASCULAR SMOOTH MUSCLE;

ALPHA7 NICOTINIC ACETYLCHOLINE RECEPTOR; ANIMALS; AORTA, THORACIC; AORTIC DISEASES; APOLIPOPROTEINS E; ATHEROSCLEROSIS; BONE MARROW TRANSPLANTATION; CELL DEGRANULATION; CELLS, CULTURED; CHOLESTEROL; COLLAGEN; DIET, HIGH-FAT; DISEASE MODELS, ANIMAL; DISEASE PROGRESSION; FOAM CELLS; GENETIC PREDISPOSITION TO DISEASE; MACROPHAGES, PERITONEAL; MALE; MAST CELLS; MICE, KNOCKOUT; MUSCLE, SMOOTH, VASCULAR; NICOTINE; NICOTINIC AGONISTS; NICOTINIC ANTAGONISTS; PHENOTYPE; PLAQUE, ATHEROSCLEROTIC; PROTO-ONCOGENE PROTEINS C-KIT; SIGNAL TRANSDUCTION; TIME FACTORS;

EID: 84995444899     PISSN: 10795642     EISSN: 15244636     Source Type: Journal    
DOI: 10.1161/ATVBAHA.116.307264     Document Type: Article

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