-
1
-
-
0003964363
-
-
Atlanta, American Cancer Society
-
American Cancer Society. Cancer Facts & Figures 2017. Atlanta: American Cancer Society; 2017.
-
(2017)
Cancer Facts & Figures 2017
-
-
-
2
-
-
84861839077
-
Estimations of the increasing prevalence and plateau prevalence of chronic myeloid leukemia in the era of tyrosine kinase inhibitor therapy
-
Huang X, Cortes J, Kantarjian H. Estimations of the increasing prevalence and plateau prevalence of chronic myeloid leukemia in the era of tyrosine kinase inhibitor therapy. Cancer. 2012;118(12):3123–3127.
-
(2012)
Cancer.
, vol.118
, Issue.12
, pp. 3123-3127
-
-
Huang, X.1
Cortes, J.2
Kantarjian, H.3
-
3
-
-
0015694748
-
Letter: A new consistent chromosomal abnormality in chronic myelogenous leukaemia identified by quinacrine fluorescence and Giemsa staining
-
Rowley JD. Letter: A new consistent chromosomal abnormality in chronic myelogenous leukaemia identified by quinacrine fluorescence and Giemsa staining. Nature. 1973;243(5405):290–293.
-
(1973)
Nature.
, vol.243
, Issue.5405
, pp. 290-293
-
-
Rowley, J.D.1
-
4
-
-
0027296354
-
Role of p21 RAS in p210 bcr-abl transformation of murine myeloid cells
-
Mandanas RA, Leibowitz DS, Gharehbaghi K, et al. Role of p21 RAS in p210 bcr-abl transformation of murine myeloid cells. Blood. 1993;82(6):1838–1847.
-
(1993)
Blood.
, vol.82
, Issue.6
, pp. 1838-1847
-
-
Mandanas, R.A.1
Leibowitz, D.S.2
Gharehbaghi, K.3
-
5
-
-
0027998224
-
Factor independence of human myeloid leukemia cell lines is associated with increased phosphorylation of the proto-oncogene Raf-1
-
Okuda K, Matulonis U, Salgia R, Kanakura Y, Druker B, Griffin JD. Factor independence of human myeloid leukemia cell lines is associated with increased phosphorylation of the proto-oncogene Raf-1. Exp Hematol. 1994;22(11):1111–1117.
-
(1994)
Exp Hematol.
, vol.22
, Issue.11
, pp. 1111-1117
-
-
Okuda, K.1
Matulonis, U.2
Salgia, R.3
Kanakura, Y.4
Druker, B.5
Griffin, J.D.6
-
6
-
-
0029589929
-
The Bcr-Abl leukemia oncogene activates Jun kinase and requires Jun for transformation
-
Raitano AB, Halpern JR, Hambuch TM, Sawyers CL. The Bcr-Abl leukemia oncogene activates Jun kinase and requires Jun for transformation. Proc Natl Acad Sci USA. 1995;92(25):11746–11750.
-
(1995)
Proc Natl Acad Sci USA.
, vol.92
, Issue.25
, pp. 11746-11750
-
-
Raitano, A.B.1
Halpern, J.R.2
Hambuch, T.M.3
Sawyers, C.L.4
-
7
-
-
0026788001
-
Dominant negative MYC blocks transformation by ABL oncogenes
-
Sawyers CL, Callahan W, Witte ON. Dominant negative MYC blocks transformation by ABL oncogenes. Cell. 1992;70(6):901–910.
-
(1992)
Cell.
, vol.70
, Issue.6
, pp. 901-910
-
-
Sawyers, C.L.1
Callahan, W.2
Witte, O.N.3
-
8
-
-
0029810923
-
Constitutive activation of STAT5 by the BCR-ABL oncogene in chronic myelogenous leukemia
-
Shuai K, Halpern J, ten Hoeve J, Rao X, Sawyers CL. Constitutive activation of STAT5 by the BCR-ABL oncogene in chronic myelogenous leukemia. Oncogene. 1996;13(2):247–254.
-
(1996)
Oncogene.
, vol.13
, Issue.2
, pp. 247-254
-
-
Shuai, K.1
Halpern, J.2
ten Hoeve, J.3
Rao, X.4
Sawyers, C.L.5
-
9
-
-
0029863169
-
Tyrosyl phosphorylation and DNA binding activity of signal transducers and activators of transcription (STAT) proteins in hematopoietic cell lines transformed by Bcr/Abl
-
Carlesso N, Frank DA, Griffin JD. Tyrosyl phosphorylation and DNA binding activity of signal transducers and activators of transcription (STAT) proteins in hematopoietic cell lines transformed by Bcr/Abl. J Exp Med. 1996;183(3):811–820.
-
(1996)
J Exp Med.
, vol.183
, Issue.3
, pp. 811-820
-
-
Carlesso, N.1
Frank, D.A.2
Griffin, J.D.3
-
10
-
-
0000506439
-
P210 and P190 (BCR/ABL) induce the tyrosine phosphorylation and DNA binding activity of multiple specific STAT family members
-
Ilaria RL, Jr, Van Etten RA. P210 and P190 (BCR/ABL) induce the tyrosine phosphorylation and DNA binding activity of multiple specific STAT family members. J Biol Chem. 1996;271(49):31704–31710.
-
(1996)
J Biol Chem.
, vol.271
, Issue.49
, pp. 31704-31710
-
-
Ilaria, R.L.1
Van Etten, R.A.2
-
11
-
-
13044294682
-
An evidence-based analysis of the effect of busulfan, hydroxyurea, interferon, and allogeneic bone marrow transplantation in treating the chronic phase of chronic myeloid leukemia: developed for the American Society of Hematology
-
Silver RT, Woolf SH, Hehlmann R, et al. An evidence-based analysis of the effect of busulfan, hydroxyurea, interferon, and allogeneic bone marrow transplantation in treating the chronic phase of chronic myeloid leukemia: developed for the American Society of Hematology. Blood. 1999;94(5):1517–1536.
-
(1999)
Blood.
, vol.94
, Issue.5
, pp. 1517-1536
-
-
Silver, R.T.1
Woolf, S.H.2
Hehlmann, R.3
-
12
-
-
77949767505
-
International randomized study of interferon vs. STI571 (IRIS) 8-year follow up: sustained survival and low risk for progression of events in patients with newly diagnosed chronic myeloid leukemia in chronic phase (CML-CP) treated with imatinib
-
Deininger M, O'brien SG, Guilhot F. International randomized study of interferon vs. STI571 (IRIS) 8-year follow up: sustained survival and low risk for progression of events in patients with newly diagnosed chronic myeloid leukemia in chronic phase (CML-CP) treated with imatinib. Blood. 2009;114.
-
(2009)
Blood.
, vol.114
-
-
Deininger, M.1
O'brien, S.G.2
Guilhot, F.3
-
13
-
-
43049104149
-
Molecular monitoring in chronic myeloid leukemia: response to tyrosine kinase inhibitors and prognostic implications
-
Jabbour E, Cortes JE, Kantarjian HM. Molecular monitoring in chronic myeloid leukemia: response to tyrosine kinase inhibitors and prognostic implications. Cancer. 2008;112(10):2112–2118.
-
(2008)
Cancer.
, vol.112
, Issue.10
, pp. 2112-2118
-
-
Jabbour, E.1
Cortes, J.E.2
Kantarjian, H.M.3
-
14
-
-
41349123259
-
Monitoring the response and course of chronic myeloid leukemia in the modern era of BCR-ABL tyrosine kinase inhibitors: practical advice on the use and interpretation of monitoring methods
-
Kantarjian H, Schiffer C, Jones D, Cortes J. Monitoring the response and course of chronic myeloid leukemia in the modern era of BCR-ABL tyrosine kinase inhibitors: practical advice on the use and interpretation of monitoring methods. Blood. 2008;111(4):1774–1780.
-
(2008)
Blood.
, vol.111
, Issue.4
, pp. 1774-1780
-
-
Kantarjian, H.1
Schiffer, C.2
Jones, D.3
Cortes, J.4
-
15
-
-
85009854501
-
Comparison of chromosome banding analysis, interphase- and hypermetaphase-FISH, qualitative and quantitative PCR for diagnosis and for follow-up in chronic myeloid leukemia: a study on 350 cases
-
Schoch C, Schnittger S, Bursch S, et al. Comparison of chromosome banding analysis, interphase- and hypermetaphase-FISH, qualitative and quantitative PCR for diagnosis and for follow-up in chronic myeloid leukemia: a study on 350 cases. Leukemia. 2002;16(1):53.
-
(2002)
Leukemia.
, vol.16
, Issue.1
, pp. 53
-
-
Schoch, C.1
Schnittger, S.2
Bursch, S.3
-
16
-
-
84974574951
-
Risk stratification of chromosomal abnormalities in chronic myelogenous leukemia in the era of tyrosine kinase inhibitor therapy
-
Wang W, Cortes JE, Tang G, et al. Risk stratification of chromosomal abnormalities in chronic myelogenous leukemia in the era of tyrosine kinase inhibitor therapy. Blood. 2016;127(22):2742–2750.
-
(2016)
Blood.
, vol.127
, Issue.22
, pp. 2742-2750
-
-
Wang, W.1
Cortes, J.E.2
Tang, G.3
-
17
-
-
0033987746
-
Lessons learned from the development of an abl tyrosine kinase inhibitor for chronic myelogenous leukemia
-
Druker BJ, Lydon NB. Lessons learned from the development of an abl tyrosine kinase inhibitor for chronic myelogenous leukemia. J Clin Invest. 2000;105(1):3–7.
-
(2000)
J Clin Invest.
, vol.105
, Issue.1
, pp. 3-7
-
-
Druker, B.J.1
Lydon, N.B.2
-
18
-
-
10744233716
-
Imatinib compared with interferon and low-dose cytarabine for newly diagnosed chronic-phase chronic myeloid leukemia
-
O'Brien SG, Guilhot F, Larson RA, et al. Imatinib compared with interferon and low-dose cytarabine for newly diagnosed chronic-phase chronic myeloid leukemia. N Engl J Med. 2003;348(11):994–1004.
-
(2003)
N Engl J Med.
, vol.348
, Issue.11
, pp. 994-1004
-
-
O'Brien, S.G.1
Guilhot, F.2
Larson, R.A.3
-
19
-
-
85015641837
-
Long-term outcomes of imatinib treatment for chronic myeloid leukemia
-
Hochhaus A, Larson RA, Guilhot F, et al. Long-term outcomes of imatinib treatment for chronic myeloid leukemia. N Engl J Med. 2017;376(10):917–927.
-
(2017)
N Engl J Med.
, vol.376
, Issue.10
, pp. 917-927
-
-
Hochhaus, A.1
Larson, R.A.2
Guilhot, F.3
-
20
-
-
85019768656
-
A multicenter prospective study on efficacy and safety of imatinib generics: A report from Polish Adult Leukemia Group imatinib generics registry
-
Sacha T, Góra-Tybor J, Szarejko M, et al. A multicenter prospective study on efficacy and safety of imatinib generics: A report from Polish Adult Leukemia Group imatinib generics registry. Am J Hematol. 2017;92(7):E125–E128.
-
(2017)
Am J Hematol.
, vol.92
, Issue.7
, pp. E125-E128
-
-
Sacha, T.1
Góra-Tybor, J.2
Szarejko, M.3
-
21
-
-
85048964968
-
India Generic imatinib in chronic myeloid leukemia: survival of the cheapest
-
Madhav D. India Generic imatinib in chronic myeloid leukemia: survival of the cheapest. Blood. 2016;128:abstract 630.
-
(2016)
Blood.
, vol.128
-
-
Madhav, D.1
-
22
-
-
75749105885
-
Phase III, randomized, open-label study of daily imatinib mesylate 400 mg versus 800 mg in patients with newly diagnosed, previously untreated chronic myeloid leukemia in chronic phase using molecular end points: tyrosine kinase inhibitor optimization and selectivity study
-
Cortes JE, Baccarani M, Guilhot F, et al. Phase III, randomized, open-label study of daily imatinib mesylate 400 mg versus 800 mg in patients with newly diagnosed, previously untreated chronic myeloid leukemia in chronic phase using molecular end points: tyrosine kinase inhibitor optimization and selectivity study. J Clin Oncol. 2010;28:424–430.
-
(2010)
J Clin Oncol.
, vol.28
, pp. 424-430
-
-
Cortes, J.E.1
Baccarani, M.2
Guilhot, F.3
-
23
-
-
78650625238
-
Imatinib plus peginterferon alfa-2a in chronic myeloid leukemia
-
Preudhomme C, Guilhot J, Nicolini FE, et al. Imatinib plus peginterferon alfa-2a in chronic myeloid leukemia. N Engl J Med. 2010;363(26):2511–2521.
-
(2010)
N Engl J Med.
, vol.363
, Issue.26
, pp. 2511-2521
-
-
Preudhomme, C.1
Guilhot, J.2
Nicolini, F.E.3
-
24
-
-
85045524483
-
Final evaluation of randomized CML-study IV: 10-year survival and evolution of terminal phase
-
Hehlmann R, Lauseker M, Saussele S, et al. Final evaluation of randomized CML-study IV: 10-year survival and evolution of terminal phase. Blood. 2017;130:abstract 897.
-
(2017)
Blood.
, vol.130
-
-
Hehlmann, R.1
Lauseker, M.2
Saussele, S.3
-
25
-
-
19944428353
-
Discovery of N-(2-chloro-6-methyl- phenyl)-2-(6-(4-(2-hydroxyethyl)- piperazin-1-yl)-2-methylpyrimidin-4- ylamino)thiazole-5-carboxamide (BMS-354825), a dual Src/Abl kinase inhibitor with potent antitumor activity in preclinical assays
-
Lombardo LJ, Lee FY, Chen P, et al. Discovery of N-(2-chloro-6-methyl- phenyl)-2-(6-(4-(2-hydroxyethyl)- piperazin-1-yl)-2-methylpyrimidin-4- ylamino)thiazole-5-carboxamide (BMS-354825), a dual Src/Abl kinase inhibitor with potent antitumor activity in preclinical assays. J Med Chem. 2004;47(27):6658–6661.
-
(2004)
J Med Chem.
, vol.47
, Issue.27
, pp. 6658-6661
-
-
Lombardo, L.J.1
Lee, F.Y.2
Chen, P.3
-
26
-
-
21144451094
-
In vitro activity of Bcr-Abl inhibitors AMN107 and BMS-354825 against clinically relevant imatinib-resistant Abl kinase domain mutants
-
O'Hare T, Walters DK, Stoffregen EP, et al. In vitro activity of Bcr-Abl inhibitors AMN107 and BMS-354825 against clinically relevant imatinib-resistant Abl kinase domain mutants. Cancer Res. 2005;65(11):4500–4505.
-
(2005)
Cancer Res.
, vol.65
, Issue.11
, pp. 4500-4505
-
-
O'Hare, T.1
Walters, D.K.2
Stoffregen, E.P.3
-
27
-
-
33745283618
-
The structure of Dasatinib (BMS-354825) bound to activated ABL kinase domain elucidates its inhibitory activity against imatinib-resistant ABL mutants
-
Tokarski JS, Newitt JA, Chang CY, et al. The structure of Dasatinib (BMS-354825) bound to activated ABL kinase domain elucidates its inhibitory activity against imatinib-resistant ABL mutants. Cancer Res. 2006;66(11):5790–5797.
-
(2006)
Cancer Res.
, vol.66
, Issue.11
, pp. 5790-5797
-
-
Tokarski, J.S.1
Newitt, J.A.2
Chang, C.Y.3
-
28
-
-
3142676436
-
Overriding imatinib resistance with a novel ABL kinase inhibitor
-
Shah NP, Tran C, Lee FY, et al. Overriding imatinib resistance with a novel ABL kinase inhibitor. Science. 2004;305(5682):399–401.
-
(2004)
Science.
, vol.305
, Issue.5682
, pp. 399-401
-
-
Shah, N.P.1
Tran, C.2
Lee, F.Y.3
-
29
-
-
77953725855
-
Dasatinib versus imatinib in newly diagnosed chronic-phase chronic myeloid leukemia
-
Kantarjian H, Shah NP, Hochhaus A, et al. Dasatinib versus imatinib in newly diagnosed chronic-phase chronic myeloid leukemia. N Engl J Med. 2010;362(24):2260–2270.
-
(2010)
N Engl J Med.
, vol.362
, Issue.24
, pp. 2260-2270
-
-
Kantarjian, H.1
Shah, N.P.2
Hochhaus, A.3
-
30
-
-
84977485123
-
Final 5-year study results of DASISION: the dasatinib versus imatinib study in treatment-naïve chronic myeloid leukemia patients trial
-
Cortes JE, Saglio G, Kantarjian HM, et al. Final 5-year study results of DASISION: the dasatinib versus imatinib study in treatment-naïve chronic myeloid leukemia patients trial. J Clin Oncol. 2016;34(20):2333–2340.
-
(2016)
J Clin Oncol.
, vol.34
, Issue.20
, pp. 2333-2340
-
-
Cortes, J.E.1
Saglio, G.2
Kantarjian, H.M.3
-
31
-
-
84868552615
-
A randomized trial of dasatinib 100 mg versus imatinib 400 mg in newly diagnosed chronic-phase chronic myeloid leukemia
-
Radich JP, Kopecky KJ, Appelbaum FR, et al. A randomized trial of dasatinib 100 mg versus imatinib 400 mg in newly diagnosed chronic-phase chronic myeloid leukemia. Blood. 2012;120(19):3898–3905.
-
(2012)
Blood.
, vol.120
, Issue.19
, pp. 3898-3905
-
-
Radich, J.P.1
Kopecky, K.J.2
Appelbaum, F.R.3
-
32
-
-
84942316053
-
Spiri6 2: An NCRI randomized study comparing dasatinib with imatinib in patients with newly diagnosed CML
-
O'Brien SG, Hedgley C, Adams S, et al. Spiri6 2: An NCRI randomized study comparing dasatinib with imatinib in patients with newly diagnosed CML. Blood (ASH Annual Meeting Abstracts). 2014;124:517.
-
(2014)
Blood (ASH Annual Meeting Abstracts).
, vol.124
, pp. 517
-
-
O'Brien, S.G.1
Hedgley, C.2
Adams, S.3
-
33
-
-
33745102555
-
Dasatinib in imatinib-resistant Philadelphia chromosome-positive leukemias
-
Talpaz M, Shah NP, Kantarjian H, et al. Dasatinib in imatinib-resistant Philadelphia chromosome-positive leukemias. N Engl J Med. 2006;354(24):2531–2541.
-
(2006)
N Engl J Med.
, vol.354
, Issue.24
, pp. 2531-2541
-
-
Talpaz, M.1
Shah, N.P.2
Kantarjian, H.3
-
34
-
-
84983070734
-
Dasatinib in imatinib-resistant or -intolerant chronic-phase, chronic myeloid leukemia patients: 7-year follow-up of study CA180-034
-
Shah NP, Rousselot P, Schiffer C, et al. Dasatinib in imatinib-resistant or -intolerant chronic-phase, chronic myeloid leukemia patients: 7-year follow-up of study CA180-034. Am J Hematol. 2016;91(9):869–874.
-
(2016)
Am J Hematol.
, vol.91
, Issue.9
, pp. 869-874
-
-
Shah, N.P.1
Rousselot, P.2
Schiffer, C.3
-
35
-
-
85036497908
-
Impact of dose reductions on 5-year efficacy in newly diagnosed patients with chronic myeloid leukemia in chronic phase (CML-CP) from DASISION
-
Cortes J, Hochhaus A, Kantarjian H, et al. Impact of dose reductions on 5-year efficacy in newly diagnosed patients with chronic myeloid leukemia in chronic phase (CML-CP) from DASISION. Am Soc Clin Oncol. 2017;abstract 3036.
-
(2017)
Am Soc Clin Oncol.
-
-
Cortes, J.1
Hochhaus, A.2
Kantarjian, H.3
-
36
-
-
85065349299
-
Evaluating the role of lower dose dasatinib in newly diagnosed early chronic phase-chronic myeloid leukemia (CML-CP)
-
Naqvi K, Cortes J, Skinner J, et al. Evaluating the role of lower dose dasatinib in newly diagnosed early chronic phase-chronic myeloid leukemia (CML-CP). Blood. 2017;130:abstract 1611.
-
(2017)
Blood.
, pp. 130:
-
-
Naqvi, K.1
Cortes, J.2
Skinner, J.3
-
37
-
-
13844251975
-
Characterization of AMN107, a selective inhibitor of native and mutant Bcr-Abl
-
Weisberg E, Manley PW, Breitenstein W, et al. Characterization of AMN107, a selective inhibitor of native and mutant Bcr-Abl. Cancer Cell. 2005;7(2):129–141.
-
(2005)
Cancer Cell.
, vol.7
, Issue.2
, pp. 129-141
-
-
Weisberg, E.1
Manley, P.W.2
Breitenstein, W.3
-
38
-
-
77953691179
-
Nilotinib versus imatinib for newly diagnosed chronic myeloid leukemia
-
Saglio G, Kim DW, Issaragrisil S, et al. Nilotinib versus imatinib for newly diagnosed chronic myeloid leukemia. N Engl J Med. 2010;362(24):2251–2259.
-
(2010)
N Engl J Med.
, vol.362
, Issue.24
, pp. 2251-2259
-
-
Saglio, G.1
Kim, D.W.2
Issaragrisil, S.3
-
39
-
-
84959482245
-
Long-term benefits and risks of frontline nilotinib vs imatinib for chronic myeloid leukemia in chronic phase: 5-year update of the randomized ENESTnd trial
-
Hochhaus A, Saglio G, Hughes TP, et al. Long-term benefits and risks of frontline nilotinib vs imatinib for chronic myeloid leukemia in chronic phase: 5-year update of the randomized ENESTnd trial. Leukemia. 2016;30(5):1044–1054.
-
(2016)
Leukemia.
, vol.30
, Issue.5
, pp. 1044-1054
-
-
Hochhaus, A.1
Saglio, G.2
Hughes, T.P.3
-
40
-
-
84929494071
-
Phase 3 study of nilotinib vs imatinib in Chinese patients with newly diagnosed chronic myeloid leukemia in chronic phase: ENESTchina
-
Wang J, Shen ZX, Saglio G, et al. Phase 3 study of nilotinib vs imatinib in Chinese patients with newly diagnosed chronic myeloid leukemia in chronic phase: ENESTchina. Blood. 2015;125(18):2771–2778.
-
(2015)
Blood.
, vol.125
, Issue.18
, pp. 2771-2778
-
-
Wang, J.1
Shen, Z.X.2
Saglio, G.3
-
41
-
-
85022087279
-
Bosutinib versus Iimatinib for newly diagnosed chronic myeloid leukemia: results from the randomized BFORE Trial
-
Cortes JE, Gambacorti-Passerini C, Deininger MW, et al. Bosutinib versus Iimatinib for newly diagnosed chronic myeloid leukemia: results from the randomized BFORE Trial. J Clin Oncol. 2017.
-
(2017)
J Clin Oncol.
-
-
Cortes, J.E.1
Gambacorti-Passerini, C.2
Deininger, M.W.3
-
42
-
-
84940550022
-
Long-term molecular and cytogenetic response and survival outcomes with imatinib 400 mg, imatinib 800 mg, dasatinib, and nilotinib in patients with chronic-phase chronic myeloid leukaemia: retrospective analysis of patient data from five clinical trials
-
Jain P, Kantarjian H, Alattar ML, et al. Long-term molecular and cytogenetic response and survival outcomes with imatinib 400 mg, imatinib 800 mg, dasatinib, and nilotinib in patients with chronic-phase chronic myeloid leukaemia: retrospective analysis of patient data from five clinical trials. Lancet Haematol. 2015;2(3):e118–e128.
-
(2015)
Lancet Haematol.
, vol.2
, Issue.3
, pp. e118-e128
-
-
Jain, P.1
Kantarjian, H.2
Alattar, M.L.3
-
43
-
-
84891954191
-
Chronic myelogenous leukemia, Version 1.2014
-
O'Brien S, Radich JP, Abboud CN, et al. Chronic myelogenous leukemia, Version 1.2014. J Natl Compr Canc Netw. 2013;11:1327–1340.
-
(2013)
J Natl Compr Canc Netw.
, vol.11
, pp. 1327-1340
-
-
O'Brien, S.1
Radich, J.P.2
Abboud, C.N.3
-
44
-
-
84860346274
-
Pulmonary arterial hypertension in patients treated by dasatinib
-
Montani D, Bergot E, Gunther S, et al. Pulmonary arterial hypertension in patients treated by dasatinib. Circulation. 2012;125(17):2128–2137.
-
(2012)
Circulation.
, vol.125
, Issue.17
, pp. 2128-2137
-
-
Montani, D.1
Bergot, E.2
Gunther, S.3
-
45
-
-
67651089848
-
Tyrosine kinase inhibitor-induced platelet dysfunction in patients with chronic myeloid leukemia
-
Quintas-Cardama A, Han X, Kantarjian H, Cortes J. Tyrosine kinase inhibitor-induced platelet dysfunction in patients with chronic myeloid leukemia. Blood. 2009;114(2):261–263.
-
(2009)
Blood.
, vol.114
, Issue.2
, pp. 261-263
-
-
Quintas-Cardama, A.1
Han, X.2
Kantarjian, H.3
Cortes, J.4
-
46
-
-
66649092089
-
Bleeding diathesis in patients with chronic myeloid leukemia receiving dasatinib therapy
-
Quintas-Cardama A, Kantarjian H, Ravandi F, et al. Bleeding diathesis in patients with chronic myeloid leukemia receiving dasatinib therapy. Cancer. 2009;115(11):2482–2490.
-
(2009)
Cancer.
, vol.115
, Issue.11
, pp. 2482-2490
-
-
Quintas-Cardama, A.1
Kantarjian, H.2
Ravandi, F.3
-
47
-
-
79959361633
-
Progressive peripheral arterial occlusive disease and other vascular events during nilotinib therapy in CML
-
Aichberger KJ, Herndlhofer S, Schernthaner G, et al. Progressive peripheral arterial occlusive disease and other vascular events during nilotinib therapy in CML. Am J Hematol. 2011;86(7):533–539.
-
(2011)
Am J Hematol.
, vol.86
, Issue.7
, pp. 533-539
-
-
Aichberger, K.J.1
Herndlhofer, S.2
Schernthaner, G.3
-
49
-
-
79959340971
-
Nilotinib treatment-associated peripheral artery disease and sudden death: Yet another reason to stick to imatinib as front-line therapy for chronic myelogenous leukemia
-
Tefferi A, Letendre L. Nilotinib treatment-associated peripheral artery disease and sudden death: Yet another reason to stick to imatinib as front-line therapy for chronic myelogenous leukemia. Am J Hematol. 2011;86(7):610–611.
-
(2011)
Am J Hematol.
, vol.86
, Issue.7
, pp. 610-611
-
-
Tefferi, A.1
Letendre, L.2
-
50
-
-
84878899268
-
Rates of peripheral arterial occlusive disease in patients with chronic myeloid leukemia in the chronic phase treated with imatinib, nilotinib, or non-tyrosine kinase therapy: a retrospective cohort analysis
-
Giles FJ, Mauro MJ, Hong F, et al. Rates of peripheral arterial occlusive disease in patients with chronic myeloid leukemia in the chronic phase treated with imatinib, nilotinib, or non-tyrosine kinase therapy: a retrospective cohort analysis. Leukemia. 2013;27(6):1310–1315.
-
(2013)
Leukemia.
, vol.27
, Issue.6
, pp. 1310-1315
-
-
Giles, F.J.1
Mauro, M.J.2
Hong, F.3
-
51
-
-
79957492218
-
Bending the cost curve in cancer care
-
Smith TJ, Hillner BE. Bending the cost curve in cancer care. N Engl J Med. 2011;364(21):2060–2065.
-
(2011)
N Engl J Med.
, vol.364
, Issue.21
, pp. 2060-2065
-
-
Smith, T.J.1
Hillner, B.E.2
-
52
-
-
84886719809
-
Cancer drugs in the United States: justum pretium—the just price
-
Kantarjian HM, Fojo T, Mathisen M, Zwelling LA. Cancer drugs in the United States: justum pretium—the just price. J Clin Oncol. 2013;31(28):3600–3604.
-
(2013)
J Clin Oncol.
, vol.31
, Issue.28
, pp. 3600-3604
-
-
Kantarjian, H.M.1
Fojo, T.2
Mathisen, M.3
Zwelling, L.A.4
-
53
-
-
84880790088
-
The price of drugs for chronic myeloid leukemia is a reflection of the unsustainable prices of cancer drugs: from the perspective of a large group of CML experts
-
Experts in Chronic Myeloid Leukemia. The price of drugs for chronic myeloid leukemia is a reflection of the unsustainable prices of cancer drugs: from the perspective of a large group of CML experts. Blood. 2013;121:4439–4442.
-
(2013)
Blood.
, vol.121
, pp. 4439-4442
-
-
-
54
-
-
79953880772
-
Multicenter independent assessment of outcomes in chronic myeloid leukemia patients treated with imatinib
-
Gambacorti-Passerini C, Antolini L, Mahon X, et al. Multicenter independent assessment of outcomes in chronic myeloid leukemia patients treated with imatinib. J Natl Cancer Inst. 2011;103:553–561.
-
(2011)
J Natl Cancer Inst.
, vol.103
, pp. 553-561
-
-
Gambacorti-Passerini, C.1
Antolini, L.2
Mahon, X.3
-
55
-
-
84925632459
-
What is the most cost-effective strategy for treating newly diagnosed chronic myeloid leukemia (CML) after imatinib loses patent exclusivity?
-
Larson RA, Conti R, Padula WV, et al. What is the most cost-effective strategy for treating newly diagnosed chronic myeloid leukemia (CML) after imatinib loses patent exclusivity? Blood (ASH Annual Meeting Abstracts). 2014;124:738.
-
(2014)
Blood (ASH Annual Meeting Abstracts).
, vol.124
, pp. 738
-
-
Larson, R.A.1
Conti, R.2
Padula, W.V.3
-
56
-
-
0021336851
-
Prognostic discrimination in “good-risk” chronic granulocytic leukemia
-
Sokal JE, Cox EB, Baccarani M, et al. Prognostic discrimination in “good-risk” chronic granulocytic leukemia. Blood. 1984;63(4):789–799.
-
(1984)
Blood.
, vol.63
, Issue.4
, pp. 789-799
-
-
Sokal, J.E.1
Cox, E.B.2
Baccarani, M.3
-
57
-
-
0032478962
-
A new prognostic score for survival of patients with chronic myeloid leukemia treated with interferon Alfa
-
Hasford J, Pfirrmann M, Hehlmann R, et al. A new prognostic score for survival of patients with chronic myeloid leukemia treated with interferon Alfa. J Natl Cancer Inst. 1998;90:850–858.
-
(1998)
J Natl Cancer Inst.
, vol.90
, pp. 850-858
-
-
Hasford, J.1
Pfirrmann, M.2
Hehlmann, R.3
-
58
-
-
84881298446
-
European LeukemiaNet recommendations for the management of chronic myeloid leukemia: 2013
-
Baccarani M, Deininger MW, Rosti G, et al. European LeukemiaNet recommendations for the management of chronic myeloid leukemia: 2013. Blood. 2013;122(6):872–884.
-
(2013)
Blood.
, vol.122
, Issue.6
, pp. 872-884
-
-
Baccarani, M.1
Deininger, M.W.2
Rosti, G.3
-
59
-
-
73949153481
-
Chronic myeloid leukemia: a prospective comparison of interphase fluorescence in situ hybridization and chromosome banding analysis for the definition of complete cytogenetic response: a study of the GIMEMA CML WP
-
Testoni N, Marzocchi G, Luatti S, et al. Chronic myeloid leukemia: a prospective comparison of interphase fluorescence in situ hybridization and chromosome banding analysis for the definition of complete cytogenetic response: a study of the GIMEMA CML WP. Blood. 2009;114(24):4939–4943.
-
(2009)
Blood.
, vol.114
, Issue.24
, pp. 4939-4943
-
-
Testoni, N.1
Marzocchi, G.2
Luatti, S.3
-
60
-
-
79954986886
-
Considerations in the management of patients with Philadelphia chromosome-positive chronic myeloid leukemia receiving tyrosine kinase inhibitors
-
Kantarjian H, Cortes J. Considerations in the management of patients with Philadelphia chromosome-positive chronic myeloid leukemia receiving tyrosine kinase inhibitors. J Clin Oncol. 2011;29:1512–1516.
-
(2011)
J Clin Oncol.
, vol.29
, pp. 1512-1516
-
-
Kantarjian, H.1
Cortes, J.2
-
61
-
-
79955018499
-
Tolerability-adapted imatinib 800 mg/d versus 400 mg/d versus 400 mg/d plus interferon-alpha in newly diagnosed chronic myeloid leukemia
-
Hehlmann R, Lauseker M, Jung-Munkwitz S, et al. Tolerability-adapted imatinib 800 mg/d versus 400 mg/d versus 400 mg/d plus interferon-alpha in newly diagnosed chronic myeloid leukemia. J Clin Oncol. 2011;29:1634–1642.
-
(2011)
J Clin Oncol.
, vol.29
, pp. 1634-1642
-
-
Hehlmann, R.1
Lauseker, M.2
Jung-Munkwitz, S.3
-
62
-
-
68949108481
-
Significance of increasing levels of minimal residual disease in patients with Philadelphia chromosome-positive chronic myelogenous leukemia in complete cytogenetic response
-
Kantarjian HM, Shan J, Jones D, et al. Significance of increasing levels of minimal residual disease in patients with Philadelphia chromosome-positive chronic myelogenous leukemia in complete cytogenetic response. J Clin Oncol. 2009;27:3659–3663.
-
(2009)
J Clin Oncol.
, vol.27
, pp. 3659-3663
-
-
Kantarjian, H.M.1
Shan, J.2
Jones, D.3
-
63
-
-
84862907694
-
Assessment of BCR-ABL1 transcript levels at 3 months is the only requirement for predicting outcome for patients with chronic myeloid leukemia treated with tyrosine kinase inhibitors
-
Marin D, Ibrahim AR, Lucas C, et al. Assessment of BCR-ABL1 transcript levels at 3 months is the only requirement for predicting outcome for patients with chronic myeloid leukemia treated with tyrosine kinase inhibitors. J Clin Oncol. 2012;30:232–238.
-
(2012)
J Clin Oncol.
, vol.30
, pp. 232-238
-
-
Marin, D.1
Ibrahim, A.R.2
Lucas, C.3
-
64
-
-
84881289808
-
Early responses predict better outcomes in patients with newly diagnosed chronic myeloid leukemia: results with four tyrosine kinase inhibitor modalities
-
Jain P, Kantarjian H, Nazha A, et al. Early responses predict better outcomes in patients with newly diagnosed chronic myeloid leukemia: results with four tyrosine kinase inhibitor modalities. Blood. 2013;121(24):4867–4874.
-
(2013)
Blood.
, vol.121
, Issue.24
, pp. 4867-4874
-
-
Jain, P.1
Kantarjian, H.2
Nazha, A.3
-
65
-
-
84878263769
-
Combining BCR-ABL1 transcript level at 3 and 6 months in chronic myeloid leukemia: implications for early intervention strategies
-
Neelakantan P, Gerrard G, Lucas C, et al. Combining BCR-ABL1 transcript level at 3 and 6 months in chronic myeloid leukemia: implications for early intervention strategies. Blood. 2013;121:3739–3742.
-
(2013)
Blood.
, vol.121
, pp. 3739-3742
-
-
Neelakantan, P.1
Gerrard, G.2
Lucas, C.3
-
66
-
-
84886997780
-
Assessment at 6 months may be warranted for patients with chronic myeloid leukemia with no major cytogenetic response at 3 months
-
Nazha A, Kantarjian H, Jain P, et al. Assessment at 6 months may be warranted for patients with chronic myeloid leukemia with no major cytogenetic response at 3 months. Haematologica. 2013;98(11):1686–1688.
-
(2013)
Haematologica.
, vol.98
, Issue.11
, pp. 1686-1688
-
-
Nazha, A.1
Kantarjian, H.2
Jain, P.3
-
67
-
-
84898044952
-
Any BRC-ABL reduction below 10% at 6 months of therapy significantly improves outcome for CML patients with a poor response at 3 months
-
Branford S, Roberts N, Yeung DT, Altamura H, Parker WT, Hughes TP. Any BRC-ABL reduction below 10% at 6 months of therapy significantly improves outcome for CML patients with a poor response at 3 months. Blood (ASH Annual Meeting Abstracts). 2013;122:254.
-
(2013)
Blood (ASH Annual Meeting Abstracts).
, vol.122
, pp. 254
-
-
Branford, S.1
Roberts, N.2
Yeung, D.T.3
Altamura, H.4
Parker, W.T.5
Hughes, T.P.6
-
68
-
-
81155133285
-
Front-line therapy with second-generation tyrosine kinase inhibitors in patients with early chronic phase chronic myeloid leukemia: what is the optimal response?
-
Jabbour E, Kantarjian HM, O'brien S, et al. Front-line therapy with second-generation tyrosine kinase inhibitors in patients with early chronic phase chronic myeloid leukemia: what is the optimal response? J Clin Oncol. 2011;29:4260–4265.
-
(2011)
J Clin Oncol.
, vol.29
, pp. 4260-4265
-
-
Jabbour, E.1
Kantarjian, H.M.2
O'brien, S.3
-
69
-
-
84995480744
-
Monitoring and defining early response: Where to draw the line?
-
Branford S. Monitoring and defining early response: Where to draw the line? Best Pract Res Heamtol. 2016;29:284–294.
-
(2016)
Best Pract Res Heamtol.
, vol.29
, pp. 284-294
-
-
Branford, S.1
-
70
-
-
84997634541
-
Switching to nilotinib versus imatinib dose escalation in patients with chronic myeloid leukaemia in chronic phase with suboptimal response to imatinib (LASOR): a randomised, open-label trial
-
Cortes JE, De Souza CA, Ayala M, et al. Switching to nilotinib versus imatinib dose escalation in patients with chronic myeloid leukaemia in chronic phase with suboptimal response to imatinib (LASOR): a randomised, open-label trial. Lancet Haematol. 2016;3(12):e581–e591.
-
(2016)
Lancet Haematol.
, vol.3
, Issue.12
, pp. e581-e591
-
-
Cortes, J.E.1
De Souza, C.A.2
Ayala, M.3
-
71
-
-
85032620270
-
Sustained deep molecular responses in patients switched to nilotinib due to persistent BCR-ABL1 on imatinib: final ENESTcmr randomized trial results
-
Hughes TP, Leber B, Cervantes F, et al. Sustained deep molecular responses in patients switched to nilotinib due to persistent BCR-ABL1 on imatinib: final ENESTcmr randomized trial results. Leukemia. 2017;31(11):2529–2531.
-
(2017)
Leukemia.
, vol.31
, Issue.11
, pp. 2529-2531
-
-
Hughes, T.P.1
Leber, B.2
Cervantes, F.3
-
72
-
-
77952467377
-
Adherence is the critical factor for achieving molecular responses in patients with chronic myeloid leukemia who achieve complete cytogenetic responses on imatinib
-
Marin D, Bazeos A, Mahon FX, et al. Adherence is the critical factor for achieving molecular responses in patients with chronic myeloid leukemia who achieve complete cytogenetic responses on imatinib. J Clin Oncol. 2010;28(14):2381–2388.
-
(2010)
J Clin Oncol.
, vol.28
, Issue.14
, pp. 2381-2388
-
-
Marin, D.1
Bazeos, A.2
Mahon, F.X.3
-
73
-
-
34249782019
-
Treatment interruptions and non-adherence with imatinib and associated healthcare costs: a retrospective analysis among managed care patients with chronic myelogenous leukaemia
-
Darkow T, Henk HJ, Thomas SK, et al. Treatment interruptions and non-adherence with imatinib and associated healthcare costs: a retrospective analysis among managed care patients with chronic myelogenous leukaemia. PharmacoEconomics. 2007;25(6):481–496.
-
(2007)
PharmacoEconomics.
, vol.25
, Issue.6
, pp. 481-496
-
-
Darkow, T.1
Henk, H.J.2
Thomas, S.K.3
-
74
-
-
67049087117
-
Prevalence, determinants, and outcomes of nonadherence to imatinib therapy in patients with chronic myeloid leukemia: the ADAGIO study
-
Noens L, van Lierde MA, De Bock R, et al. Prevalence, determinants, and outcomes of nonadherence to imatinib therapy in patients with chronic myeloid leukemia: the ADAGIO study. Blood. 2009;113(22):5401–5411.
-
(2009)
Blood.
, vol.113
, Issue.22
, pp. 5401-5411
-
-
Noens, L.1
van Lierde, M.A.2
De Bock, R.3
-
75
-
-
85041424001
-
-
Sprycel® (dasatinib) prescribing information. Princeton, NJ;
-
Bristol-Myers Squibb Company. Sprycel® (dasatinib) prescribing information. Princeton, NJ; 2011.
-
(2011)
-
-
-
76
-
-
85041426265
-
-
Tasigna® (nilotinib) prescribing information. East Hanover, NJ;
-
Novartis Pharmaceuticals Corporation. Tasigna® (nilotinib) prescribing information. East Hanover, NJ; 2011.
-
(2011)
-
-
-
77
-
-
64049099666
-
Imatinib mesylate dose escalation is associated with durable responses in patients with chronic myeloid leukemia after cytogenetic failure on standard-dose imatinib therapy
-
Jabbour E, Kantarjian HM, Jones D, et al. Imatinib mesylate dose escalation is associated with durable responses in patients with chronic myeloid leukemia after cytogenetic failure on standard-dose imatinib therapy. Blood. 2009;113(10):2154–2160.
-
(2009)
Blood.
, vol.113
, Issue.10
, pp. 2154-2160
-
-
Jabbour, E.1
Kantarjian, H.M.2
Jones, D.3
-
78
-
-
70149105272
-
Dasatinib or high-dose imatinib for chronic-phase chronic myeloid leukemia resistant to imatinib at a dose of 400 to 600 milligrams daily: two-year follow-up of a randomized phase 2 study (START-R)
-
Kantarjian H, Pasquini R, Levy V, et al. Dasatinib or high-dose imatinib for chronic-phase chronic myeloid leukemia resistant to imatinib at a dose of 400 to 600 milligrams daily: two-year follow-up of a randomized phase 2 study (START-R). Cancer. 2009;115(18):4136–4147.
-
(2009)
Cancer.
, vol.115
, Issue.18
, pp. 4136-4147
-
-
Kantarjian, H.1
Pasquini, R.2
Levy, V.3
-
79
-
-
84875904733
-
Impact of second-generation tyrosine kinase inhibitors as second line treatment for patients with chronic myeloid leukemia
-
Garcia-Gutierrez JV, Herrera P, Abalo LL, Rey MD, Calbacho M. Impact of second-generation tyrosine kinase inhibitors as second line treatment for patients with chronic myeloid leukemia. Blood. 2011;118:632.
-
(2011)
Blood.
, vol.118
, pp. 632
-
-
Garcia-Gutierrez, J.V.1
Herrera, P.2
Abalo, L.L.3
Rey, M.D.4
Calbacho, M.5
-
80
-
-
84872649780
-
Efficacy of nilotinib versus high-dose imatinib in early chronic phase CML patients who have suboptimal molecular responses to standard-dose imatinib (RE-NICE multicenter study)
-
Goh HG, Jootar S, Kim HJ, Sohn SK, Park JS, Kim SH. Efficacy of nilotinib versus high-dose imatinib in early chronic phase CML patients who have suboptimal molecular responses to standard-dose imatinib (RE-NICE multicenter study). Blood. 2011;118:632.
-
(2011)
Blood.
, vol.118
, pp. 632
-
-
Goh, H.G.1
Jootar, S.2
Kim, H.J.3
Sohn, S.K.4
Park, J.S.5
Kim, S.H.6
-
81
-
-
80055070888
-
Safety and efficacy of bosutinib (SKI-606) in chronic phase Philadelphia chromosome-positive chronic myeloid leukemia patients with resistance or intolerance to imatinib
-
Cortes JE, Kantarjian HM, Brummendorf TH, et al. Safety and efficacy of bosutinib (SKI-606) in chronic phase Philadelphia chromosome-positive chronic myeloid leukemia patients with resistance or intolerance to imatinib. Blood. 2011;118(17):4567–4576.
-
(2011)
Blood.
, vol.118
, Issue.17
, pp. 4567-4576
-
-
Cortes, J.E.1
Kantarjian, H.M.2
Brummendorf, T.H.3
-
82
-
-
84861694293
-
Upfront imatinib therapy in CML patients with rapid switching to nilotinib for failure to achieve molecular targets or intolerance achieves high overall rates of molecular response and a low risk of progression - an update of the TIDEL-II trial
-
Yeung DT, Osborn M, White DL, Branford S, Kornhauser M, Slader C. Upfront imatinib therapy in CML patients with rapid switching to nilotinib for failure to achieve molecular targets or intolerance achieves high overall rates of molecular response and a low risk of progression - an update of the TIDEL-II trial. Blood. 2011;118:632.
-
(2011)
Blood.
, vol.118
, pp. 632
-
-
Yeung, D.T.1
Osborn, M.2
White, D.L.3
Branford, S.4
Kornhauser, M.5
Slader, C.6
-
83
-
-
67649624660
-
Dasatinib early intervention after cytogenetic or hematologic resistance to imatinib in patients with chronic myeloid leukemia
-
Quintas-Cardama A, Cortes JE, O'brien S, et al. Dasatinib early intervention after cytogenetic or hematologic resistance to imatinib in patients with chronic myeloid leukemia. Cancer. 2009;115(13):2912–2921.
-
(2009)
Cancer.
, vol.115
, Issue.13
, pp. 2912-2921
-
-
Quintas-Cardama, A.1
Cortes, J.E.2
O'brien, S.3
-
84
-
-
70350507997
-
AP24534, a pan-BCR-ABL inhibitor for chronic myeloid leukemia, potently inhibits the T315I mutant and overcomes mutation-based resistance
-
O'Hare T, Shakespeare WC, Zhu X, et al. AP24534, a pan-BCR-ABL inhibitor for chronic myeloid leukemia, potently inhibits the T315I mutant and overcomes mutation-based resistance. Cancer Cell. 2009;16:401–412.
-
(2009)
Cancer Cell.
, vol.16
, pp. 401-412
-
-
O'Hare, T.1
Shakespeare, W.C.2
Zhu, X.3
-
85
-
-
78650159009
-
Structural mechanism of the pan-BCR-ABL inhibitor ponatinib (AP24534): lessons for overcoming kinase inhibitor resistance
-
Zhou T, Commodore L, Huang WS, et al. Structural mechanism of the pan-BCR-ABL inhibitor ponatinib (AP24534): lessons for overcoming kinase inhibitor resistance. Chem Biol Drug Des. 2011;77:1–11.
-
(2011)
Chem Biol Drug Des.
, vol.77
, pp. 1-11
-
-
Zhou, T.1
Commodore, L.2
Huang, W.S.3
-
86
-
-
84887127701
-
A phase 2 trial of ponatinib in Philadelphia chromosome-positive leukemias
-
Cortes JE, Kim DW, Pinilla-Ibarz J, et al. A phase 2 trial of ponatinib in Philadelphia chromosome-positive leukemias. N Engl J Med. 2013;369(19):1783–1796.
-
(2013)
N Engl J Med.
, vol.369
, Issue.19
, pp. 1783-1796
-
-
Cortes, J.E.1
Kim, D.W.2
Pinilla-Ibarz, J.3
-
87
-
-
85036497908
-
Five-year results of the ponatinib phase II PACE trial in heavily pretreated CP-CML patients
-
Kantarjian HM, Pinilla-Ibarz J, Le Coutre PD, et al. Five-year results of the ponatinib phase II PACE trial in heavily pretreated CP-CML patients. Am Soc Clin Oncol. 2017;abstract 7012.
-
(2017)
Am Soc Clin Oncol.
-
-
Kantarjian, H.M.1
Pinilla-Ibarz, J.2
Le Coutre, P.D.3
-
89
-
-
85018402656
-
The allosteric inhibitor ABL001 enables dual targeting of BCR-ABL1
-
Wylie AA, Schoepfer J, Jahnke W, et al. The allosteric inhibitor ABL001 enables dual targeting of BCR-ABL1. Nature. 2017;543(7647):733–737.
-
(2017)
Nature.
, vol.543
, Issue.7647
, pp. 733-737
-
-
Wylie, A.A.1
Schoepfer, J.2
Jahnke, W.3
-
90
-
-
85026268350
-
Expanded phase 1 study of ABL001, a potent, allosteric inhibitor of BCR-ABL, reveals significant and durable responses in patients with CML-chronic phase with failure of prior TKI therapy
-
Hughes TP, Goh YT, Ottmann OG, et al. Expanded phase 1 study of ABL001, a potent, allosteric inhibitor of BCR-ABL, reveals significant and durable responses in patients with CML-chronic phase with failure of prior TKI therapy. Blood. 2016;128:abstract 625.
-
(2016)
Blood.
, vol.128
-
-
Hughes, T.P.1
Goh, Y.T.2
Ottmann, O.G.3
-
91
-
-
37049003546
-
Dynamics of BCR-ABL kinase domain mutations in chronic myeloid leukemia after sequential treatment with multiple tyrosine kinase inhibitors
-
Cortes J, Jabbour E, Kantarjian H, et al. Dynamics of BCR-ABL kinase domain mutations in chronic myeloid leukemia after sequential treatment with multiple tyrosine kinase inhibitors. Blood. 2007;110(12):4005–4011.
-
(2007)
Blood.
, vol.110
, Issue.12
, pp. 4005-4011
-
-
Cortes, J.1
Jabbour, E.2
Kantarjian, H.3
-
92
-
-
79955400117
-
Practical advice for determining the role of BCR-ABL mutations in guiding tyrosine kinase inhibitor therapy in patients with chronic myeloid leukemia
-
Jabbour E, Branford S, Saglio G, Jones D, Cortes JE, Kantarjian HM. Practical advice for determining the role of BCR-ABL mutations in guiding tyrosine kinase inhibitor therapy in patients with chronic myeloid leukemia. Cancer. 2011;117(9):1800–1811.
-
(2011)
Cancer.
, vol.117
, Issue.9
, pp. 1800-1811
-
-
Jabbour, E.1
Branford, S.2
Saglio, G.3
Jones, D.4
Cortes, J.E.5
Kantarjian, H.M.6
-
93
-
-
73949105873
-
Dasatinib treatment of chronic-phase chronic myeloid leukemia: analysis of responses according to preexisting BCR-ABL mutations
-
Müller MC, Cortes JE, Kim D-W, et al. Dasatinib treatment of chronic-phase chronic myeloid leukemia: analysis of responses according to preexisting BCR-ABL mutations. Blood. 2009;114(24):4944–4953.
-
(2009)
Blood.
, vol.114
, Issue.24
, pp. 4944-4953
-
-
Müller, M.C.1
Cortes, J.E.2
Kim, D.-W.3
-
94
-
-
70249105789
-
Impact of baseline BCR-ABL mutations on response to nilotinib in patients with chronic myeloid leukemia in chronic phase
-
Hughes T, Saglio G, Branford S, et al. Impact of baseline BCR-ABL mutations on response to nilotinib in patients with chronic myeloid leukemia in chronic phase. J Clin Oncol. 2009;27(25):4204–4210.
-
(2009)
J Clin Oncol.
, vol.27
, Issue.25
, pp. 4204-4210
-
-
Hughes, T.1
Saglio, G.2
Branford, S.3
-
95
-
-
84896622957
-
Bosutinib safety and management of toxicity in leukemia patients with resistance or intolerance to imatinib and other tyrosine kinase inhibitors
-
Kantarjian HM, Cortes JE, Kim DW, et al. Bosutinib safety and management of toxicity in leukemia patients with resistance or intolerance to imatinib and other tyrosine kinase inhibitors. Blood. 2014;123(9):1309–1318.
-
(2014)
Blood.
, vol.123
, Issue.9
, pp. 1309-1318
-
-
Kantarjian, H.M.1
Cortes, J.E.2
Kim, D.W.3
-
96
-
-
84877773183
-
The achievement of a 3-month complete cytogenetic response to second-generation tyrosine kinase inhibitors predicts survival in patients with chronic phase chronic myeloid leukemia after imatinib failure
-
Jabbour E, Kantarjian H, Ghanem H, et al. The achievement of a 3-month complete cytogenetic response to second-generation tyrosine kinase inhibitors predicts survival in patients with chronic phase chronic myeloid leukemia after imatinib failure. Clin Lymphoma Myeloma Leuk. 2013;13(3):302–306.
-
(2013)
Clin Lymphoma Myeloma Leuk.
, vol.13
, Issue.3
, pp. 302-306
-
-
Jabbour, E.1
Kantarjian, H.2
Ghanem, H.3
-
97
-
-
79953689908
-
Results of allogeneic hematopoietic stem cell transplantation for chronic myelogenous leukemia patients who failed tyrosine kinase inhibitors after developing BCR-ABL1 kinase domain mutations
-
Jabbour E, Cortes J, Santos FP, et al. Results of allogeneic hematopoietic stem cell transplantation for chronic myelogenous leukemia patients who failed tyrosine kinase inhibitors after developing BCR-ABL1 kinase domain mutations. Blood. 2011;117(13):3641–3647.
-
(2011)
Blood.
, vol.117
, Issue.13
, pp. 3641-3647
-
-
Jabbour, E.1
Cortes, J.2
Santos, F.P.3
-
98
-
-
54049146732
-
Impact of prior imatinib mesylate on the outcome of hematopoietic cell transplantation for chronic myeloid leukemia
-
Lee SJ, Kukreja M, Wang T, et al. Impact of prior imatinib mesylate on the outcome of hematopoietic cell transplantation for chronic myeloid leukemia. Blood. 2008;112(8):3500–3507.
-
(2008)
Blood.
, vol.112
, Issue.8
, pp. 3500-3507
-
-
Lee, S.J.1
Kukreja, M.2
Wang, T.3
-
99
-
-
47549110816
-
Therapeutic choices in patients with Ph-positive CML living in Mexico in the tyrosine kinase inhibitor era: SCT or TKIs?
-
Ruiz-Argüelles GJ, Tarin-Arzaga LC, Gonzalez-Carrillo ML, et al. Therapeutic choices in patients with Ph-positive CML living in Mexico in the tyrosine kinase inhibitor era: SCT or TKIs? Bone Marrow Transplant. 2008;42(1):23–28.
-
(2008)
Bone Marrow Transplant.
, vol.42
, Issue.1
, pp. 23-28
-
-
Ruiz-Argüelles, G.J.1
Tarin-Arzaga, L.C.2
Gonzalez-Carrillo, M.L.3
-
100
-
-
84927588605
-
Cost structure and clinical outcome of a stem cell transplantation program in a developing country: the experience in northeast Mexico
-
Jaime-Pérez JC, Heredia-Salazar AC, Cantú-Rodríguez OG, et al. Cost structure and clinical outcome of a stem cell transplantation program in a developing country: the experience in northeast Mexico. Oncologist. 2015;20(4):386–392.
-
(2015)
Oncologist.
, vol.20
, Issue.4
, pp. 386-392
-
-
Jaime-Pérez, J.C.1
Heredia-Salazar, A.C.2
Cantú-Rodríguez, O.G.3
-
101
-
-
78049528573
-
Discontinuation of imatinib in patients with chronic myeloid leukaemia who have maintained complete molecular remission for at least 2 years: the prospective, multicentre Stop Imatinib (STIM) trial
-
Mahon FX, Rea D, Guilhot J, et al. Discontinuation of imatinib in patients with chronic myeloid leukaemia who have maintained complete molecular remission for at least 2 years: the prospective, multicentre Stop Imatinib (STIM) trial. Lancet Oncol. 2010;11(11):1029–1035.
-
(2010)
Lancet Oncol.
, vol.11
, Issue.11
, pp. 1029-1035
-
-
Mahon, F.X.1
Rea, D.2
Guilhot, J.3
-
102
-
-
84886917643
-
Safety and efficacy of imatinib cessation for CML patients with stable undetectable minimal residual disease: results from the TWISTER study
-
Ross DM, Branford S, Seymour JF, et al. Safety and efficacy of imatinib cessation for CML patients with stable undetectable minimal residual disease: results from the TWISTER study. Blood. 2013;122(4):515–522.
-
(2013)
Blood.
, vol.122
, Issue.4
, pp. 515-522
-
-
Ross, D.M.1
Branford, S.2
Seymour, J.F.3
-
103
-
-
85014926522
-
Discontinuation of dasatinib or nilotinib in chronic myeloid leukemia: interim analysis of the STOP 2G-TKI study
-
Rea D, Nicolini FE, Tulliez M, et al. Discontinuation of dasatinib or nilotinib in chronic myeloid leukemia: interim analysis of the STOP 2G-TKI study. Blood. 2017;129(7):846–854.
-
(2017)
Blood.
, vol.129
, Issue.7
, pp. 846-854
-
-
Rea, D.1
Nicolini, F.E.2
Tulliez, M.3
-
104
-
-
85018406029
-
Cessation of tyrosine kinase inhibitors treatment in chronic myeloid leukemia patients with deep molecular response: results of the euro-ski trial
-
Mahon FX, Richter J, Guilhot J, et al. Cessation of tyrosine kinase inhibitors treatment in chronic myeloid leukemia patients with deep molecular response: results of the euro-ski trial. Blood. 2016;128(22):787–787.
-
(2016)
Blood.
, vol.128
, Issue.22
, pp. 787
-
-
Mahon, F.X.1
Richter, J.2
Guilhot, J.3
-
106
-
-
84954289990
-
Chronic myeloid leukemia: First-line drug of choice
-
Jabbour E. Chronic myeloid leukemia: First-line drug of choice. Am J Hematol. 2016;91(1):59–66.
-
(2016)
Am J Hematol.
, vol.91
, Issue.1
, pp. 59-66
-
-
Jabbour, E.1
-
107
-
-
84979255197
-
Cost-effectiveness of tyrosine kinase inhibitor treatment strategies for chronic myeloid leukemia in chronic phase after generic entry of imatinib in the United States
-
Padula WV, Larson RA, Dusetzina SB, et al. Cost-effectiveness of tyrosine kinase inhibitor treatment strategies for chronic myeloid leukemia in chronic phase after generic entry of imatinib in the United States. J Natl Cancer Inst. 2016;108(7).
-
(2016)
J Natl Cancer Inst.
, vol.108
, Issue.7
-
-
Padula, W.V.1
Larson, R.A.2
Dusetzina, S.B.3
-
108
-
-
84941933185
-
Are high drug prices for hematologic malignancies justified? A critical analysis
-
Chhatwal J, Mathisen M, Kantarjian H. Are high drug prices for hematologic malignancies justified? A critical analysis. Cancer. 2015;121(19):3372–3379.
-
(2015)
Cancer.
, vol.121
, Issue.19
, pp. 3372-3379
-
-
Chhatwal, J.1
Mathisen, M.2
Kantarjian, H.3
-
109
-
-
85016335649
-
The chronic myeloid leukemia stem cell: stemming the tide of persistence
-
Holyoake TL, Vetrie D. The chronic myeloid leukemia stem cell: stemming the tide of persistence. Blood. 2017;129(12):1595–1606.
-
(2017)
Blood.
, vol.129
, Issue.12
, pp. 1595-1606
-
-
Holyoake, T.L.1
Vetrie, D.2
-
110
-
-
85016335649
-
The chronic myeloid leukemia stem cell: stemming the tide of persistence
-
Holyoake TL, Vetrie D. The chronic myeloid leukemia stem cell: stemming the tide of persistence. Blood. 2017;129(12):1595–1606.
-
(2017)
Blood.
, vol.129
, Issue.12
, pp. 1595-1606
-
-
Holyoake, T.L.1
Vetrie, D.2
-
111
-
-
80053130415
-
Combination of pegylated IFN-alpha2b with imatinib increases molecular response rates in patients with low- or intermediate-risk chronic myeloid leukemia
-
Simonsson B, Gedde-Dahl T, Markevarn B, et al. Combination of pegylated IFN-alpha2b with imatinib increases molecular response rates in patients with low- or intermediate-risk chronic myeloid leukemia. Blood. 2011;118(12):3228–3235.
-
(2011)
Blood.
, vol.118
, Issue.12
, pp. 3228-3235
-
-
Simonsson, B.1
Gedde-Dahl, T.2
Markevarn, B.3
-
112
-
-
84973163267
-
Safety and efficacy of the combination of pegylated interferon-alpha2b and dasatinib in newly diagnosed chronic-phase chronic myeloid leukemia patients
-
Hjorth-Hansen H, Stentoft J, Richter J, et al. Safety and efficacy of the combination of pegylated interferon-alpha2b and dasatinib in newly diagnosed chronic-phase chronic myeloid leukemia patients. Leukemia. 2016;30(9):1853–1860.
-
(2016)
Leukemia.
, vol.30
, Issue.9
, pp. 1853-1860
-
-
Hjorth-Hansen, H.1
Stentoft, J.2
Richter, J.3
-
113
-
-
84988805216
-
Combined targeting of BCL-2 and BCR-ABL tyrosine kinase eradicates chronic myeloid leukemia stem cells
-
Carter BZ, Mak PY, Mu H, et al. Combined targeting of BCL-2 and BCR-ABL tyrosine kinase eradicates chronic myeloid leukemia stem cells. Sci Transl Med. 2016;8(355):355ra117.
-
(2016)
Sci Transl Med.
, vol.8
, Issue.355
, pp. 355ra117
-
-
Carter, B.Z.1
Mak, P.Y.2
Mu, H.3
-
114
-
-
84910071851
-
The BCL2 inhibitor ABT-199 significantly enhances imatinib-induced cell death in chronic myeloid leukemia progenitors
-
Ko TK, Chuah CT, Huang JW, Ng KP, Ong ST. The BCL2 inhibitor ABT-199 significantly enhances imatinib-induced cell death in chronic myeloid leukemia progenitors. Oncotarget. 2014;5(19):9033–9038.
-
(2014)
Oncotarget.
, vol.5
, Issue.19
, pp. 9033-9038
-
-
Ko, T.K.1
Chuah, C.T.2
Huang, J.W.3
Ng, K.P.4
Ong, S.T.5
-
115
-
-
78650710470
-
Sustained exposure to the DNA demethylating agent, 2'-deoxy-5-azacytidine, leads to apoptotic cell death in chronic myeloid leukemia by promoting differentiation, senescence, and autophagy
-
Schnekenburger M, Grandjenette C, Ghelfi J, et al. Sustained exposure to the DNA demethylating agent, 2'-deoxy-5-azacytidine, leads to apoptotic cell death in chronic myeloid leukemia by promoting differentiation, senescence, and autophagy. Biochem Pharmacol. 2011;81(3):364–378.
-
(2011)
Biochem Pharmacol.
, vol.81
, Issue.3
, pp. 364-378
-
-
Schnekenburger, M.1
Grandjenette, C.2
Ghelfi, J.3
-
116
-
-
84907368130
-
JAK2/STAT5 inhibition by nilotinib with ruxolitinib contributes to the elimination of CML CD34+ cells in vitro and in vivo
-
Gallipoli P, Cook A, Rhodes S, et al. JAK2/STAT5 inhibition by nilotinib with ruxolitinib contributes to the elimination of CML CD34+ cells in vitro and in vivo. Blood. 2014;124(9):1492–1501.
-
(2014)
Blood.
, vol.124
, Issue.9
, pp. 1492-1501
-
-
Gallipoli, P.1
Cook, A.2
Rhodes, S.3
-
117
-
-
84888037897
-
Advances in immunotherapy of chronic myeloid leukemia CML
-
Held SA, Heine A, Mayer KT, Kapelle M, Wolf DG, Brossart P. Advances in immunotherapy of chronic myeloid leukemia CML. Curr Cancer Drug Targets. 2013;13(7):768–774.
-
(2013)
Curr Cancer Drug Targets.
, vol.13
, Issue.7
, pp. 768-774
-
-
Held, S.A.1
Heine, A.2
Mayer, K.T.3
Kapelle, M.4
Wolf, D.G.5
Brossart, P.6
-
118
-
-
70249141675
-
Dasatinib in the treatment of chronic myeloid leukemia in accelerated phase after imatinib failure: the START-A trial
-
Apperley JF, Cortes JE, Kim DW, et al. Dasatinib in the treatment of chronic myeloid leukemia in accelerated phase after imatinib failure: the START-A trial. J Clin Oncol. 2009;27:3472–3479.
-
(2009)
J Clin Oncol.
, vol.27
, pp. 3472-3479
-
-
Apperley, J.F.1
Cortes, J.E.2
Kim, D.W.3
-
119
-
-
33846925617
-
The effects of imatinib mesylate treatment before allogeneic transplantation for chronic myeloid leukemia
-
Oehler VG, Gooley T, Snyder DS, et al. The effects of imatinib mesylate treatment before allogeneic transplantation for chronic myeloid leukemia. Blood. 2007;109(4):1782–1789.
-
(2007)
Blood.
, vol.109
, Issue.4
, pp. 1782-1789
-
-
Oehler, V.G.1
Gooley, T.2
Snyder, D.S.3
-
120
-
-
33947587233
-
Prophylactic administration of imatinib after hematopoietic cell transplantation for high-risk Philadelphia chromosome-positive leukemia
-
Carpenter PA, Snyder DS, Flowers ME, et al. Prophylactic administration of imatinib after hematopoietic cell transplantation for high-risk Philadelphia chromosome-positive leukemia. Blood. 2007;109(7):2791–2793.
-
(2007)
Blood.
, vol.109
, Issue.7
, pp. 2791-2793
-
-
Carpenter, P.A.1
Snyder, D.S.2
Flowers, M.E.3
-
121
-
-
34547178987
-
Novel tyrosine kinase inhibitor therapy before allogeneic stem cell transplantation in patients with chronic myeloid leukemia: no evidence for increased transplant-related toxicity
-
Jabbour E, Cortes J, Kantarjian H, et al. Novel tyrosine kinase inhibitor therapy before allogeneic stem cell transplantation in patients with chronic myeloid leukemia: no evidence for increased transplant-related toxicity. Cancer. 2007;110(2):340–344.
-
(2007)
Cancer.
, vol.110
, Issue.2
, pp. 340-344
-
-
Jabbour, E.1
Cortes, J.2
Kantarjian, H.3
-
122
-
-
84862028031
-
Nilotinib in patients with Ph+ chronic myeloid leukemia in accelerated phase following imatinib resistance or intolerance: 24-month follow-up results
-
Le Coutre PD, Giles FJ, Hochhaus A, et al. Nilotinib in patients with Ph+ chronic myeloid leukemia in accelerated phase following imatinib resistance or intolerance: 24-month follow-up results. Leukemia. 2012;26(6):1189–1194.
-
(2012)
Leukemia.
, vol.26
, Issue.6
, pp. 1189-1194
-
-
Le Coutre, P.D.1
Giles, F.J.2
Hochhaus, A.3
-
123
-
-
2942567555
-
Treatment of Philadelphia chromosome-positive acute lymphocytic leukemia with hyper-CVAD and imatinib mesylate
-
Thomas DA, Faderl S, Cortes J, et al. Treatment of Philadelphia chromosome-positive acute lymphocytic leukemia with hyper-CVAD and imatinib mesylate. Blood. 2004;103(12):4396–4407.
-
(2004)
Blood.
, vol.103
, Issue.12
, pp. 4396-4407
-
-
Thomas, D.A.1
Faderl, S.2
Cortes, J.3
-
124
-
-
77957191745
-
First report of phase 2 study of dasatinib with hyper-CVAD for the frontline treatment of patients with Philadelphia chromosome-positive (Ph+) acute lymphoblastic leukemia
-
Ravandi F, O'brien S, Thomas D, et al. First report of phase 2 study of dasatinib with hyper-CVAD for the frontline treatment of patients with Philadelphia chromosome-positive (Ph+) acute lymphoblastic leukemia. Blood. 2010;116(12):2070–2077.
-
(2010)
Blood.
, vol.116
, Issue.12
, pp. 2070-2077
-
-
Ravandi, F.1
O'brien, S.2
Thomas, D.3
-
125
-
-
34247853362
-
A pilot study of imatinib, low-dose cytarabine and idarubicin for patients with chronic myeloid leukemia in myeloid blast phase
-
Quintas-Cardama A, Kantarjian H, Garcia-Manero G, et al. A pilot study of imatinib, low-dose cytarabine and idarubicin for patients with chronic myeloid leukemia in myeloid blast phase. Leuk Lymphoma. 2007;48(2):283–289.
-
(2007)
Leuk Lymphoma.
, vol.48
, Issue.2
, pp. 283-289
-
-
Quintas-Cardama, A.1
Kantarjian, H.2
Garcia-Manero, G.3
-
126
-
-
85026356485
-
Prognostic factors and survival outcomes in patients with chronic myeloid leukemia in blast phase in the tyrosine kinase inhibitor era: Cohort study of 477 patients
-
Jain P, Kantarjian HM, Ghorab A, et al. Prognostic factors and survival outcomes in patients with chronic myeloid leukemia in blast phase in the tyrosine kinase inhibitor era: Cohort study of 477 patients. Cancer. 2017;123(22):4391–4402.
-
(2017)
Cancer.
, vol.123
, Issue.22
, pp. 4391-4402
-
-
Jain, P.1
Kantarjian, H.M.2
Ghorab, A.3
-
127
-
-
84896405273
-
Tyrosine kinase inhibitors as initial therapy for patients with chronic myeloid leukemia in accelerated phase
-
Ohanian M, Kantarjian HM, Quintas-Cardama A, et al. Tyrosine kinase inhibitors as initial therapy for patients with chronic myeloid leukemia in accelerated phase. Clin Lymphoma Myeloma Leuk. 2014;14(2):155–162.
-
(2014)
Clin Lymphoma Myeloma Leuk.
, vol.14
, Issue.2
, pp. 155-162
-
-
Ohanian, M.1
Kantarjian, H.M.2
Quintas-Cardama, A.3
|