-
1
-
-
10744233716
-
Imatinib compared with interferon and low-dose cytarabine for newly diagnosed chronic-phase chronic myeloid leukemia
-
DOI 10.1056/NEJMoa022457
-
O'Brien SG, Guilhot F, Larson Ra, et al: Imatinib compared with interferon and low-dose cytarabine for newly diagnosed chronic-phase chronic myeloid leukemia. N Engl J Med 348:994-1004, 2003 (Pubitemid 36302244)
-
(2003)
New England Journal of Medicine
, vol.348
, Issue.11
, pp. 994-1004
-
-
O'Brien, S.G.1
Guilhot, F.2
Larson, R.A.3
Gathmann, I.4
Baccarani, M.5
Cervantes, F.6
Cornelissen, J.J.7
Fischer, T.8
Hochhaus, A.9
Hughes, T.10
Lechner, K.11
Nielsen, J.L.12
Rousselot, P.13
Reiffers, J.14
Saglio, G.15
Shepherd, J.16
Simonsson, B.17
Gratwohl, A.18
Goldman, J.M.19
Kantarjian, H.20
Taylor, K.21
Verhoef, G.22
Bolton, A.E.23
Capdeville, R.24
Druker, B.J.25
more..
-
2
-
-
33845444046
-
Five-year follow-up of patients receiving imatinib for chronic myeloid leukemia
-
DOI 10.1056/NEJMoa062867
-
Druker B, Guilhot F, O'Brien S, et al: Five-year follow-up of patients receiving imatinib for chronic myeloid leukemia. N Engl J Med 355:2408-2417, 2006 (Pubitemid 44903745)
-
(2006)
New England Journal of Medicine
, vol.355
, Issue.23
, pp. 2408-2417
-
-
Druker, B.J.1
Guilhot, F.2
O'Brien, S.G.3
Gathmann, I.4
Kantarjian, H.5
Gattermann, N.6
Deininger, M.W.N.7
Silver, R.T.8
Goldman, J.M.9
Stone, R.M.10
Cervantes, F.11
Hochhaus, A.12
Powell, B.L.13
Gabrilove, J.L.14
Rousselot, P.15
Reiffers, J.16
Cornelissen, J.J.17
Hughes, T.18
Agis, H.19
Fischer, T.20
Verhoef, G.21
Shepherd, J.22
Saglio, G.23
Gratwohl, A.24
Nielsen, J.L.25
Radich, J.P.26
Simonsson, B.27
Taylor, K.28
Baccarani, M.29
So, C.30
Letvak, L.31
Larson, R.A.32
more..
-
3
-
-
68549097002
-
International randomized study of interferon versus STI571 (IRIS) 7-year follow-up: Sustained survival low rate of transformation and increased rate of major molecular response (MMR) in patients (pts) with newly diagnosed chronic myeloid leukemia in chronic phase (CML-CP) treated with imatinib (IM)
-
(abstr 186
-
O'Brien SG, Guilhot F, Goodman JM, et al: International randomized study of interferon versus STI571 (IRIS) 7-year follow-up: Sustained survival, low rate of transformation and increased rate of major molecular response (MMR) in patients (pts) with newly diagnosed chronic myeloid leukemia in chronic phase (CML-CP) treated with imatinib (IM). Blood 112:76, 2008 (abstr 186)
-
(2008)
Blood
, vol.112
, pp. 76
-
-
O'Brien, S.G.1
Guilhot, F.2
Goodman, J.M.3
-
4
-
-
33748696341
-
Survival benefit with imatinib mesylate versus interferon-α-based regimens in newly diagnosed chronic-phase chronic myelogenous leukemia
-
DOI 10.1182/blood-2006-02-004325
-
Kantarjian H, Talpaz M, O'Brien S, et al: Survival benefit with imatinib mesylate versus interferon -α-based regimens in newly diagnosed chronic-phase chronic myelogenous leukemia. Blood 108:1835-1840, 2006 (Pubitemid 44394991)
-
(2006)
Blood
, vol.108
, Issue.6
, pp. 1835-1840
-
-
Kantarjian, H.M.1
Talpaz, M.2
O'Brien, S.3
Jones, D.4
Giles, F.5
Garcia-Manero, G.6
Faderl, S.7
Ravandi, F.8
Rios, M.B.9
Shan, J.10
Cortes, J.11
-
5
-
-
79955047243
-
Chronic myeloid leukemia
-
in Hong W Bast R Hait W et al (eds) (ed 8). Shelton, CT, People's Medical Publishing House
-
Cortes J, Silver R, Kantarjian H: Chronic myeloid leukemia, in Hong W, Bast R, Hait W, et al (eds): Cancer Medicine (ed 8). Shelton, CT, People's Medical Publishing House, 2010, pp 1582-1590
-
(2010)
Cancer Medicine
, pp. 1582-1590
-
-
Cortes, J.1
Silver, R.2
Kantarjian, H.3
-
6
-
-
33745086350
-
Nilotinib in imatinib-resistant CML and Philadelphia chromosome-positive ALL
-
DOI 10.1056/NEJMoa055104
-
Kantarjian H, Giles F, Wunderle L, et al: Nilotinib in imatinib-resistant CML and Philadelphia chromosome-positive ALL. N Engl J Med 354; 24:2542-2551, 2006 (Pubitemid 43882350)
-
(2006)
New England Journal of Medicine
, vol.354
, Issue.24
, pp. 2542-2551
-
-
Kantarjian, H.1
Giles, F.2
Wunderle, L.3
Bhalla, K.4
O'Brien, S.5
Wassmann, B.6
Tanaka, C.7
Manley, P.8
Rae, P.9
Mietlowski, W.10
Bochinski, K.11
Hochhaus, A.12
Griffin, J.D.13
Hoelzer, D.14
Albitar, M.15
Dugan, M.16
Cortes, J.17
Alland, L.18
Ottmann, O.G.19
-
7
-
-
36348968931
-
Nilotinib (formerly AMN107), a highly selective BCR-ABL tyrosine kinase inhibitor, is effective in patients with Philadelphia chromosome-positive chronic myelogenous leukemia in chronic phase following imatinib resistance and intolerance
-
DOI 10.1182/blood-2007-03-080689
-
Kantarjian HM, Giles F, Gattermann N, et al: Nilotinib (formerly amn107), a highly selective BCR-ABL tyrosine kinase inhibitor, is effective in patients with Philadelphia chromosome-positive chronic myelogenous leukemia in chronic phase following imatinib resistance and intolerance. Blood 110:3540-3546, 2007 (Pubitemid 350159618)
-
(2007)
Blood
, vol.110
, Issue.10
, pp. 3540-3546
-
-
Kantarjian, H.M.1
Giles, F.2
Gattermann, N.3
Bhalla, K.4
Alimena, G.5
Palandri, F.6
Ossenkoppele, G.J.7
Nicolini, F.-E.8
O'Brien, S.G.9
Litzow, M.10
Bhatia, R.11
Cervantes, F.12
Haque, A.13
Shou, Y.14
Resta, D.J.15
Weitzman, A.16
Hochhaus, A.17
Le Coutre, P.18
-
8
-
-
33947280081
-
Dasatinib induces notable hematologic and cytogenetic responses in chronic-phase chronic myeloid leukemia after failure of imatinib therapy
-
DOI 10.1182/blood-2006-09-047266
-
Hochhaus A, Kantarjian H, Baccarani M, et al: Dasatinib induces notable hematologic and cytogenetic responses in chronic-phase chronic myeloid leukemia after failure of imatinib therapy. Blood 109:2303-2309, 2007 (Pubitemid 46425867)
-
(2007)
Blood
, vol.109
, Issue.6
, pp. 2303-2309
-
-
Hochhaus, A.1
Kantarjian, H.M.2
Baccarani, M.3
Lipton, J.H.4
Apperley, J.F.5
Druker, B.J.6
Facon, T.7
Goldberg, S.L.8
Cervantes, F.9
Niederwieser, D.10
Silver, R.T.11
Stone, R.M.12
Hughes, T.P.13
Muller, M.C.14
Ezzeddine, R.15
Countouriotis, A.M.16
Shah, N.P.17
-
9
-
-
77953725855
-
Dasatinib versus imatinib in newly diagnosed chronic-phase chronic myeloid leukemia
-
Kantarjian H, Shah NP, Hochhaus A, et al: Dasatinib versus imatinib in newly diagnosed chronic-phase chronic myeloid leukemia. N Engl J Med 362: 2260-2270, 2010
-
(2010)
N Engl J Med
, vol.362
, pp. 2260-2270
-
-
Kantarjian, H.1
Shah, N.P.2
Hochhaus, A.3
-
10
-
-
77953691179
-
Nilotinib versus imatinib for newly diagnosed chronic myeloid leukemia
-
Saglio G, Kim DW, Issaragrisil S, et al: Nilotinib versus imatinib for newly diagnosed chronic myeloid leukemia. N Engl J Med 362:2251-2259, 2010
-
(2010)
N Engl J Med
, vol.362
, pp. 2251-2259
-
-
Saglio, G.1
Kim, D.W.2
Issaragrisil, S.3
-
11
-
-
79955018499
-
Tolerability-adapted imatinib 800 mg/d versus 400 mg/d versus 400 mg/d plus interferonα- in newly diagnosed chronic myeloid leukemia
-
Hehlmann R, Lauseker M, Jung-Munkwitz S, et al: Tolerability-adapted imatinib 800 mg/d versus 400 mg/d versus 400 mg/d plus interferonα- in newly diagnosed chronic myeloid leukemia. J Clin Oncol 29:1634-1642, 2011
-
(2011)
J Clin Oncol
, vol.29
, pp. 1634-1642
-
-
Hehlmann, R.1
Lauseker, M.2
Jung-Munkwitz, S.3
-
12
-
-
0037441629
-
Complete cytogenetic and molecular responses to interferon-α-based therapy for chronic myelogenous leukemia are associated with excellent long-term prognosis
-
DOI 10.1002/cncr.11223
-
Kantarjian H, O'Brien S, Cortes J, et al: Complete cytogenetic and molecular responses to interferon-alpha-based therapy for chronic myelogenous leukemia are associated with excellent long-term prognosis. Cancer 97:1033- 1041, 20030 (Pubitemid 36173155)
-
(2003)
Cancer
, vol.97
, Issue.4
, pp. 1033-1041
-
-
Kantarjian, H.M.1
O'Brien, S.2
Cortes, J.E.3
Shan, J.4
Giles, F.J.5
Rios, M.B.6
Faderl, S.H.7
Wierda, W.G.8
Ferrajoli, A.9
Verstovsek, S.10
Keating, M.J.11
Freireich, E.J.12
Talpaz, M.13
-
13
-
-
10744229080
-
Frequency of major molecular responses to imatinib or interferon alfa plus cytarabine in newly diagnosed chronic myeloid leukemia
-
DOI 10.1056/NEJMoa030513
-
Hughes TP, Kaeda J, Branford S, et al: Frequency of major molecular responses to imatinib or interferon alfa plus cytarabine in newly diagnosed chronic myeoid leukemia. N Engl J Med 349:1423-1432, 2003 (Pubitemid 37211057)
-
(2003)
New England Journal of Medicine
, vol.349
, Issue.15
, pp. 1423-1432
-
-
Hughes, T.P.1
Kaeda, J.2
Branford, S.3
Rudzki, Z.4
Hochhaus, A.5
Hensley, M.L.6
Gathmann, I.7
Bolton, A.E.8
Van Hoomissen, I.C.9
Goldman, J.M.10
Radich, J.P.11
-
14
-
-
68949108481
-
Significance of increasing levels of minimal residual disease in patients with Philadelphia chromosome-positive chronic myelogenous leukemia in complete cytogenetic response
-
Kantarjian H, Shan J, Jones D, et al: Significance of increasing levels of minimal residual disease in patients with Philadelphia chromosome-positive chronic myelogenous leukemia in complete cytogenetic response. J Clin Oncol 27:3659-3663, 2009
-
(2009)
J Clin Oncol
, vol.27
, pp. 3659-3663
-
-
Kantarjian, H.1
Shan, J.2
Jones, D.3
-
15
-
-
33744463354
-
BCR-ABL mRNA levels at and after the time of a complete cytogenetic response (CCR) predict the duration of CCR in imatinib mesylate-treated patients with CML
-
DOI 10.1182/blood-2005-11-4406
-
Press R, Love Z, Tronnes A, et al: BCR-ABL mRNA levels at and after the time of a complete cytogenetic response (CCR) predict the duration of CCR in imatinib mesylate-treated patients with CML. Blood 107:4250-4256, 2006 (Pubitemid 43801348)
-
(2006)
Blood
, vol.107
, Issue.11
, pp. 4250-4256
-
-
Press, R.D.1
Love, Z.2
Tronnes, A.A.3
Yang, R.4
Tran, T.5
Mongoue-Tchokote, S.6
Mori, M.7
Mauro, M.J.8
Deininger, M.W.9
Druker, B.J.10
-
16
-
-
33745603988
-
Monitoring CML patients responding to treatment with tyrosine kinase inhibitors: Review and recommendations for harmonizing current methodology for detecting BCR-ABL transcripts and kinase domain mutations and for expressing results
-
DOI 10.1182/blood-2006-01-0092
-
Hughes TP, Deininger MW, Hochhaus A, et al: Monitoring CML patients responding to treatment with tyrosine kinase inhibitors-review and recommendations for "harmonizing" current methodology for detecting BCR-ABL transcripts and kinase domain mutations and for expressing results. Blood 108:28-37, 2006 (Pubitemid 43990609)
-
(2006)
Blood
, vol.108
, Issue.1
, pp. 28-37
-
-
Hughes, T.1
Deininger, M.2
Hochhaus, A.3
Branford, S.4
Radich, J.5
Kaeda, J.6
Baccarani, M.7
Cortes, J.8
Cross, N.C.P.9
Druker, B.J.10
Gabert, J.11
Grimwade, D.12
Hehlmann, R.13
Kamel-Reid, S.14
Lipton, J.H.15
Longtine, J.16
Martinelli, G.17
Saglio, G.18
Soverini, S.19
Stock, W.20
Goldman, J.M.21
more..
-
17
-
-
41349123259
-
Monitoring the response and course of chronic myeloid leukemia in the modern era of BCR-ABL tyrosine kinase inhibitors: Practical advice on the use and interpretation of monitoring methods
-
DOI 10.1182/blood-2007-09-110189
-
Kantarjian H, Schiffer C, Jones D, et al: Monitoring the response and course of chronic myeloid leukemia in the modern era of BCR-ABL tyrosine kinase inhibitors: Practical advice on the use and interpretation of monitoring methods. Blood 111:1774-1780, 2008 (Pubitemid 351451481)
-
(2008)
Blood
, vol.111
, Issue.4
, pp. 1774-1780
-
-
Kantarjian, H.1
Schiffer, C.2
Jones, D.3
Cortes, J.4
-
18
-
-
77956034332
-
Early intervention during imatinib therapy in patients with newly diagnosed chronic-phase chronic myeloid leukemia: A study of the Spanish PETHEMA group
-
Cervantes F, Lopez-Garrido P, Montero MI, et al: Early intervention during imatinib therapy in patients with newly diagnosed chronic-phase chronic myeloid leukemia: A study of the Spanish PETHEMA group. Haematologica 95:1317, 2010
-
(2010)
Haematologica
, vol.95
, pp. 1317
-
-
Cervantes, F.1
Lopez-Garrido, P.2
Montero, M.I.3
-
19
-
-
67649624660
-
Dasatinib early intervention after cytogenetic or hematologic resistance to imatinib in patients with chronic myeloid leukemia
-
Quintas-Cardama A, Cortes J, O'Brien S, et al: Dasatinib early intervention after cytogenetic or hematologic resistance to imatinib in patients with chronic myeloid leukemia. Cancer 115:2912-2921, 2009
-
(2009)
Cancer
, vol.115
, pp. 2912-2921
-
-
Quintas-Cardama, A.1
Cortes, J.2
O'Brien, S.3
-
20
-
-
77958595179
-
Long-term prognostic significance of early molecular response to imatinib in newly diagnosed chronic myeloid leukemia: An analysis from the International Randomized Study of Interferon and STI571 (IRIS)
-
Hughes TP, Hochhaus A, Branford S, et al: Long-term prognostic significance of early molecular response to imatinib in newly diagnosed chronic myeloid leukemia: An analysis from the International Randomized Study of Interferon and STI571 (IRIS). Blood 116:3758-3765, 2010
-
(2010)
Blood
, vol.116
, pp. 3758-3765
-
-
Hughes, T.P.1
Hochhaus, A.2
Branford, S.3
-
21
-
-
49149111543
-
Imatinib for newly diagnosed patients with chronic myeloid leukemia: Incidence of sustained responses in an intention to treat analysis
-
de Lavallade H, Apperley J, Khorashad J, et al: Imatinib for newly diagnosed patients with chronic myeloid leukemia: Incidence of sustained responses in an intention to treat analysis. J Clin Oncol 26:3358-3363, 2008
-
(2008)
J Clin Oncol
, vol.26
, pp. 3358-3363
-
-
De Lavallade, H.1
Apperley, J.2
Khorashad, J.3
-
22
-
-
33747154547
-
Evolving concepts in the management of chronic myeloid leukemia: Recommendations from an expert panel on behalf of the European LeukemiaNet
-
DOI 10.1182/blood-2006-02-005686
-
Baccarani M, Saglio G, Goldman J, et al: Evolving concepts in the management of chronic myeloid leukemia: Recommendations from an expert panel on behalf of the European LeukemiaNet. Blood 108:1809-1820, 2006 (Pubitemid 44394987)
-
(2006)
Blood
, vol.108
, Issue.6
, pp. 1809-1820
-
-
Baccarani, M.1
Saglio, G.2
Goldman, J.3
Hochhaus, A.4
Simonsson, B.5
Appelbaum, F.6
Apperley, J.7
Cervantes, F.8
Cortes, J.9
Deininger, M.10
Gratwohl, A.11
Guilhot, F.12
Horowitz, M.13
Hughes, T.14
Kantarjian, H.15
Larson, R.16
Niederwieser, D.17
Silver, R.18
Hehlmann, R.19
-
23
-
-
70450277223
-
Harmonization of molecular monitoring of CML therapy in Europe
-
Muller MC, Cross NCP, Erben P, et al: Harmonization of molecular monitoring of CML therapy in Europe. Leukemia 23:1957-1963, 2009
-
(2009)
Leukemia
, vol.23
, pp. 1957-1963
-
-
Muller, M.C.1
Cross, N.C.P.2
Erben, P.3
-
24
-
-
73949153481
-
Chronic myeloid leukemia: A prospective comparison of interphase fluorescence in situ hybridization and chromosome banding analysis for the definition of complete cytogenetic response: A study of the GIMEMA CML WP
-
Testoni N, Marzocchi G, Luatti S, et al: Chronic myeloid leukemia: A prospective comparison of interphase fluorescence in situ hybridization and chromosome banding analysis for the definition of complete cytogenetic response: A study of the GIMEMA CML WP. Blood 114:4939-4943, 2009
-
(2009)
Blood
, vol.114
, pp. 4939-4943
-
-
Testoni, N.1
Marzocchi, G.2
Luatti, S.3
-
25
-
-
35548971639
-
Chromosomal abnormalities in Philadelphia chromosome-negative metaphases appearing during imatinib mesylate therapy in patients with newly diagnosed chronic myeloid leukemia in chronic phase
-
DOI 10.1182/blood-2007-01-070045
-
Jabbour E, Kantarjian H, Abruzzo L, et al: Chromosomal abnormalities in Philadelphia chromosome-negative metaphases appearing during imatinib mesylate therapy in patients with newly diagnosed chronic myeloid leukemia in chronic phase. Blood 110:2991-2995, 2007 (Pubitemid 350006953)
-
(2007)
Blood
, vol.110
, Issue.8
, pp. 2991-2995
-
-
Jabbour, E.1
Kantarjian, H.M.2
Abruzzo, L.V.3
O'Brien, S.4
Garcia-Manero, G.5
Verstovsek, S.6
Shan, J.7
Rios, M.B.8
Cortes, J.9
-
26
-
-
58549088155
-
Activity of bosutinib, dasatinib, and nilotinib against 18 imatinib-resistant BCR/ABL mutants
-
Redaelli S, Piazza R, Rostagno R, et al: Activity of bosutinib, dasatinib, and nilotinib against 18 imatinib-resistant BCR/ABL mutants. J Clin Oncol 27:469-471, 2009
-
(2009)
J Clin Oncol
, vol.27
, pp. 469-471
-
-
Redaelli, S.1
Piazza, R.2
Rostagno, R.3
-
27
-
-
79251503452
-
Phase I trial of AP24534 in patients with refractory chronic myeloid leukemia (CML) and hematologic malignancies
-
abstr 6511
-
Talpaz M, Cortes JE, Deininger MW, et al: Phase I trial of AP24534 in patients with refractory chronic myeloid leukemia (CML) and hematologic malignancies. J Clin Oncol 28:489s, 2010 (abstr 6511)
-
(2010)
J Clin Oncol
, vol.28
-
-
Talpaz, M.1
Cortes, J.E.2
Deininger, M.W.3
-
28
-
-
43249083718
-
Imatinib pharmacokinetics and its correlation with response and safety in chronic-phase chronic myeloid leukemia: A subanalysis of the IRIS study
-
Larson R, Druker B, Guilhot F, et al: Imatinib pharmacokinetics and its correlation with response and safety in chronic-phase chronic myeloid leukemia: A subanalysis of the IRIS study. Blood 111:4022-4028, 2008
-
(2008)
Blood
, vol.111
, pp. 4022-4028
-
-
Larson, R.1
Druker, B.2
Guilhot, F.3
-
29
-
-
77952467377
-
Adherence is the critical factor for achieving molecular responses in patients with chronic myeloid leukemia who achieve complete cytogenetic responses on imatinib
-
Marin D, Bazeos A, Mahon FX, et al: Adherence is the critical factor for achieving molecular responses in patients with chronic myeloid leukemia who achieve complete cytogenetic responses on imatinib. J Clin Oncol 28:2381-2388, 2010
-
(2010)
J Clin Oncol
, vol.28
, pp. 2381-2388
-
-
Marin, D.1
Bazeos, A.2
Mahon, F.X.3
|