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Volumn 103, Issue 12, 2004, Pages 4396-4407

Treatment of Philadelphia chromosome-positive acute lymphocytic leukemia with hyper-CVAD and imatinib mesylate

Author keywords

[No Author keywords available]

Indexed keywords

BCR ABL PROTEIN; CYCLOPHOSPHAMIDE; CYTARABINE; DEXAMETHASONE; DOXORUBICIN; IMATINIB; METHOTREXATE; VINCRISTINE;

EID: 2942567555     PISSN: 00064971     EISSN: None     Source Type: Journal    
DOI: 10.1182/blood-2003-08-2958     Document Type: Article
Times cited : (479)

References (83)
  • 1
    • 0032101546 scopus 로고    scopus 로고
    • Clinical significance of cytogenetic abnormalities in adult acute lymphoblastic leukemia
    • Faderl S, Kantarjian HM, Talpaz M, Estrov Z. Clinical significance of cytogenetic abnormalities in adult acute lymphoblastic leukemia. Blood. 1998;91:3995-4019.
    • (1998) Blood , vol.91 , pp. 3995-4019
    • Faderl, S.1    Kantarjian, H.M.2    Talpaz, M.3    Estrov, Z.4
  • 2
    • 8944251627 scopus 로고    scopus 로고
    • Incidence and clinical outcome of children with BCR/ABL-positive acute lymphoblastic leukemia (ALL): A prospective RT-PCR study based on 673 patients enrolled in the German pediatric multicenter therapy trials ALL-BFM 90 and CoALL-05-92
    • Schlieben S, Borkhardt A, Reinisch I, et al. Incidence and clinical outcome of children with BCR/ABL-positive acute lymphoblastic leukemia (ALL): a prospective RT-PCR study based on 673 patients enrolled in the German pediatric multicenter therapy trials ALL-BFM 90 and CoALL-05-92. Leukemia. 1996;10:957-963.
    • (1996) Leukemia , vol.10 , pp. 957-963
    • Schlieben, S.1    Borkhardt, A.2    Reinisch, I.3
  • 3
    • 0033637411 scopus 로고    scopus 로고
    • Treatment of adult ALL according to protocols of the German Multicenter Study Group for Adult ALL (GMALL)
    • Gokbuget N, Hoelzer D, Arnold R, et al. Treatment of adult ALL according to protocols of the German Multicenter Study Group for Adult ALL (GMALL). Hematol Oncol Clin North Am. 2000;14:1307-1325.
    • (2000) Hematol Oncol Clin North Am , vol.14 , pp. 1307-1325
    • Gokbuget, N.1    Hoelzer, D.2    Arnold, R.3
  • 5
    • 0033636586 scopus 로고    scopus 로고
    • Adult acute lymphocytic leukemia study testing chemotherapy and autologous and allogeneic transplantation: A follow-up report of the French protocol LALA 87
    • Thiebaut A, Vemant JP, Degos L, et al. Adult acute lymphocytic leukemia study testing chemotherapy and autologous and allogeneic transplantation: a follow-up report of the French protocol LALA 87. Hematol Oncol Clin North Am. 2000;14:1353-1366.
    • (2000) Hematol Oncol Clin North Am , vol.14 , pp. 1353-1366
    • Thiebaut, A.1    Vemant, J.P.2    Degos, L.3
  • 6
    • 0033637892 scopus 로고    scopus 로고
    • Recent clinical trials in acute lymphocytic leukemia by the Cancer and Leukemia Group B
    • Larson RA. Recent clinical trials in acute lymphocytic leukemia by the Cancer and Leukemia Group B. Hematol Oncol Clin North Am. 2000;14:1367-1379.
    • (2000) Hematol Oncol Clin North Am , vol.14 , pp. 1367-1379
    • Larson, R.A.1
  • 7
    • 0033954540 scopus 로고    scopus 로고
    • Outcome of Philadelphia chromosome-positive adult acute lymphoblastic leukemia
    • Faderl S, Kantarjian HM, Thomas DA, et al. Outcome of Philadelphia chromosome-positive adult acute lymphoblastic leukemia. Leuk Lymphoma. 2000;36:263-273.
    • (2000) Leuk Lymphoma , vol.36 , pp. 263-273
    • Faderl, S.1    Kantarjian, H.M.2    Thomas, D.A.3
  • 8
  • 9
    • 0028238230 scopus 로고
    • Philadelphia-chromosome-positive adult acute lymphocytic leukemia: Characteristics, treatment results, and prognosis in 41 patients
    • Preti HA, O'Brien S, Giralt S, Beran M, Pierce S, Kantarjian HM. Philadelphia-chromosome-positive adult acute lymphocytic leukemia: characteristics, treatment results, and prognosis in 41 patients. Am J Med. 1994;97:60-65.
    • (1994) Am J Med , vol.97 , pp. 60-65
    • Preti, H.A.1    O'Brien, S.2    Giralt, S.3    Beran, M.4    Pierce, S.5    Kantarjian, H.M.6
  • 10
    • 0035093711 scopus 로고    scopus 로고
    • Philadelphia chromosome-positive acute lymphocytic leukemia
    • Radich JP. Philadelphia chromosome-positive acute lymphocytic leukemia. Hematol Oncol Clin North Am 2001;15:21-36.
    • (2001) Hematol Oncol Clin North Am , vol.15 , pp. 21-36
    • Radich, J.P.1
  • 11
    • 0034611661 scopus 로고    scopus 로고
    • Outcome of treatment in children with Philadelphia chromosome-positive acute lymphoblastic leukemia
    • Arico M, Valsecchi MG, Camitta B, et al. Outcome of treatment in children with Philadelphia chromosome-positive acute lymphoblastic leukemia. N Engl J Med. 2000;342:998-1006.
    • (2000) N Engl J Med , vol.342 , pp. 998-1006
    • Arico, M.1    Valsecchi, M.G.2    Camitta, B.3
  • 12
    • 0032532289 scopus 로고
    • +) childhood acute lymphoblastic leukemia: Good initial steroid response allows early prediction of a favorable treatment outcome
    • +) childhood acute lymphoblastic leukemia: good initial steroid response allows early prediction of a favorable treatment outcome. Blood. 1988;92:2730-2741.
    • (1988) Blood , vol.92 , pp. 2730-2741
    • Schrappe, M.1    Aricò, M.2    Harbott, J.3
  • 13
    • 0023201015 scopus 로고
    • Bone marrow transplantation for patients with Philadelphia chromosome-positive acute lymphoblastic leukemia
    • Forman SJ, O'Donnell MR, Nademanee AP, et al. Bone marrow transplantation for patients with Philadelphia chromosome-positive acute lymphoblastic leukemia. Blood. 1987;70:587-588.
    • (1987) Blood , vol.70 , pp. 587-588
    • Forman, S.J.1    O'Donnell, M.R.2    Nademanee, A.P.3
  • 14
    • 0026636931 scopus 로고
    • Bone marrow transplantation for Philadelphia chromosome-positive acute lymphoblastic leukemia
    • Barrett AJ, Horowitz MM, Ash RC, et al. Bone marrow transplantation for Philadelphia chromosome-positive acute lymphoblastic leukemia. Blood. 1992;79:3067-3070.
    • (1992) Blood , vol.79 , pp. 3067-3070
    • Barrett, A.J.1    Horowitz, M.M.2    Ash, R.C.3
  • 15
    • 0029075396 scopus 로고
    • Long-term follow-up of allogeneic bone marrow recipients for Philadelphia chromosome-positive acute lymphoblastic leukemia
    • Chao NJ, Blume KG, Forman SJ, Snyder DS. Long-term follow-up of allogeneic bone marrow recipients for Philadelphia chromosome-positive acute lymphoblastic leukemia. Blood 1995;85:3353-3354.
    • (1995) Blood , vol.85 , pp. 3353-3354
    • Chao, N.J.1    Blume, K.G.2    Forman, S.J.3    Snyder, D.S.4
  • 16
    • 0032756124 scopus 로고    scopus 로고
    • Long-term follow-up of 23 patients with Philadelphia chromosome-positive acute lymphoblastic leukemia treated with allogeneic bone marrow transplant in first complete remission
    • Snyder DS, Nademanee AP, O'Donnell MR, et al. Long-term follow-up of 23 patients with Philadelphia chromosome-positive acute lymphoblastic leukemia treated with allogeneic bone marrow transplant in first complete remission. Leukemia. 1999;13:2053-2058.
    • (1999) Leukemia , vol.13 , pp. 2053-2058
    • Snyder, D.S.1    Nademanee, A.P.2    O'Donnell, M.R.3
  • 17
    • 0033660393 scopus 로고    scopus 로고
    • Allogeneic stem cell transplantation for Philadelphia chromosome-positive acute lymphoblastic leukemia
    • Snyder DS. Allogeneic stem cell transplantation for Philadelphia chromosome-positive acute lymphoblastic leukemia. Biol Blood Marrow Transplant. 2000;6:597-603.
    • (2000) Biol Blood Marrow Transplant , vol.6 , pp. 597-603
    • Snyder, D.S.1
  • 18
    • 0038702520 scopus 로고    scopus 로고
    • Bone marrow transplant in Ph+ ALL patients
    • Avivi I, Goldstone AH. Bone marrow transplant in Ph+ ALL patients. Bone Marrow Transplant. 2003;31:623-632.
    • (2003) Bone Marrow Transplant , vol.31 , pp. 623-632
    • Avivi, I.1    Goldstone, A.H.2
  • 19
    • 0020972981 scopus 로고
    • Translocation of c-abl oncogene correlates with the presence of a Philadelphia chromosome in chronic myelocytic leukaemia
    • Bartram CR, de Klein A, Hagemeijer A, et al. Translocation of c-abl oncogene correlates with the presence of a Philadelphia chromosome in chronic myelocytic leukaemia. Nature. 1983;306:277-280.
    • (1983) Nature , vol.306 , pp. 277-280
    • Bartram, C.R.1    De Klein, A.2    Hagemeijer, A.3
  • 20
    • 0021802841 scopus 로고
    • Fused transcript of abl and bcr genes in chronic myeloid leukaemia
    • Shtivelman E, Lifshitz B, Gale RP, Canaani E. Fused transcript of abl and bcr genes in chronic myeloid leukaemia. Nature. 1985;315:550-554.
    • (1985) Nature , vol.315 , pp. 550-554
    • Shtivelman, E.1    Lifshitz, B.2    Gale, R.P.3    Canaani, E.4
  • 21
    • 0036493694 scopus 로고    scopus 로고
    • Leading prognostic relevance of the BCR-ABL translocation in adult acute B-lineage lymphoblastic leukemia: A prospective study of the German Multicenter Trial Group and confirmed polymerase chain reaction analysis
    • Gleissner B, Gokbuget N, Bartram CR, et al. Leading prognostic relevance of the BCR-ABL translocation in adult acute B-lineage lymphoblastic leukemia: a prospective study of the German Multicenter Trial Group and confirmed polymerase chain reaction analysis. Blood. 2002;99:1536-1543.
    • (2002) Blood , vol.99 , pp. 1536-1543
    • Gleissner, B.1    Gokbuget, N.2    Bartram, C.R.3
  • 22
    • 0026005505 scopus 로고
    • Significance of the P210 versus P190 molecular abnormalities in adults with Philadelphia chromosome-positive acute leukemia
    • Kantarjian HM, Talpaz M, Dhingra K, et al. Significance of the P210 versus P190 molecular abnormalities in adults with Philadelphia chromosome-positive acute leukemia. Blood. 1991;78:2411-2418.
    • (1991) Blood , vol.78 , pp. 2411-2418
    • Kantarjian, H.M.1    Talpaz, M.2    Dhingra, K.3
  • 23
    • 0025854412 scopus 로고
    • Philadelphia positive acute lymphoblastic leukemia in adults: Age distribution, BCR breakpoint and prognostic significance
    • Secker-Walker LM, Craig JM, Hawkins JM, Hoffbrand AV. Philadelphia positive acute lymphoblastic leukemia in adults: age distribution, BCR breakpoint and prognostic significance. Leukemia. 1991;5:196-199.
    • (1991) Leukemia , vol.5 , pp. 196-199
    • Secker-Walker, L.M.1    Craig, J.M.2    Hawkins, J.M.3    Hoffbrand, A.V.4
  • 24
    • 0031002040 scopus 로고    scopus 로고
    • Detection of bcr-abl transcripts in Philadelphia chromosome-positive acute lymphoblastic leukemia after marrow transplantation
    • Radich J, Gehly G, Lee A, et al. Detection of bcr-abl transcripts in Philadelphia chromosome-positive acute lymphoblastic leukemia after marrow transplantation. Blood. 1997;89:2602-2609.
    • (1997) Blood , vol.89 , pp. 2602-2609
    • Radich, J.1    Gehly, G.2    Lee, A.3
  • 25
    • 0025117392 scopus 로고
    • Induction of chronic myelogenous leukaemia in mice by the P210 bcr/abl gene of the Philadelphia chromosome
    • Daley GQ, Van Etten RA, Baltimore D, et al. Induction of chronic myelogenous leukaemia in mice by the P210 bcr/abl gene of the Philadelphia chromosome. Science 1990;247:824-830.
    • (1990) Science , vol.247 , pp. 824-830
    • Daley, G.Q.1    Van Etten, R.A.2    Baltimore, D.3
  • 26
    • 0025348013 scopus 로고
    • Tyrosine kinase activity and transformation potency of bcr-abl oncogene products
    • Lugo TG, Pendergast AM, Muller AJ, Witte ON. Tyrosine kinase activity and transformation potency of bcr-abl oncogene products. Science. 1990;247:1079-1082.
    • (1990) Science , vol.247 , pp. 1079-1082
    • Lugo, T.G.1    Pendergast, A.M.2    Muller, A.J.3    Witte, O.N.4
  • 27
    • 0033816156 scopus 로고    scopus 로고
    • Abl protein-tyrosine kinase inhibitor STI571 inhibits in vitro signal transduction mediated by c-kit and platelet-derived growth factor receptors
    • Buchdunger E, Cioffi CL, Law N, et al. Abl protein-tyrosine kinase inhibitor STI571 inhibits in vitro signal transduction mediated by c-kit and platelet-derived growth factor receptors. J Pharmacol Exp Ther. 2000;295:139-145.
    • (2000) J Pharmacol Exp Ther , vol.295 , pp. 139-145
    • Buchdunger, E.1    Cioffi, C.L.2    Law, N.3
  • 28
    • 0029947186 scopus 로고    scopus 로고
    • Effects of a selective inhibitor of the Abl tyrosine kinase on the growth of Bcr-Abl positive cells
    • Druker BJ, Tamura S, Buchdunger E, et al. Effects of a selective inhibitor of the Abl tyrosine kinase on the growth of Bcr-Abl positive cells. Nat Med. 1996;2:561-566.
    • (1996) Nat Med , vol.2 , pp. 561-566
    • Druker, B.J.1    Tamura, S.2    Buchdunger, E.3
  • 29
    • 0034665903 scopus 로고    scopus 로고
    • CGP57148B (STI-571) induces differentiation and apoptosis and sensitizes Bcr-Abl-positive human leukemia cells to apoptosis due to antileukemic drugs
    • Fang G, Kim CN, Perkins CL, et al. CGP57148B (STI-571) induces differentiation and apoptosis and sensitizes Bcr-Abl-positive human leukemia cells to apoptosis due to antileukemic drugs. Blood. 2000;96:2246-2253.
    • (2000) Blood , vol.96 , pp. 2246-2253
    • Fang, G.1    Kim, C.N.2    Perkins, C.L.3
  • 30
    • 15444350807 scopus 로고    scopus 로고
    • Selective inhibition of cell proliferation and BCR-ABL phosphorylation in acute lymphoblastic leukemia cells expressing Mr 190,000 BCR-ABL protein by a tyrosine kinase inhibitor (CGP-57148)
    • Beran M, Cao X, Estrov Z, et al. Selective inhibition of cell proliferation and BCR-ABL phosphorylation in acute lymphoblastic leukemia cells expressing Mr 190,000 BCR-ABL protein by a tyrosine kinase inhibitor (CGP-57148). Clin Cancer Res. 1998;4:1661-1672.
    • (1998) Clin Cancer Res , vol.4 , pp. 1661-1672
    • Beran, M.1    Cao, X.2    Estrov, Z.3
  • 31
    • 0035810147 scopus 로고    scopus 로고
    • Efficacy and safety of a specific inhibitor of the BCR-ABL tyrosine kinase in chronic myeloid leukemia
    • Druker BJ, Talpaz M, Resta DJ, et al. Efficacy and safety of a specific inhibitor of the BCR-ABL tyrosine kinase in chronic myeloid leukemia. N Engl J Med. 2001;344:1031-1037.
    • (2001) N Engl J Med , vol.344 , pp. 1031-1037
    • Druker, B.J.1    Talpaz, M.2    Resta, D.J.3
  • 32
    • 0037186915 scopus 로고    scopus 로고
    • Hematologic and cytogenetic responses to imatinib mesylate in chronic myelogenous leukemia
    • Kantarjian H, Sawyers C, Hochhaus A, et al. Hematologic and cytogenetic responses to imatinib mesylate in chronic myelogenous leukemia. N Engl J Med. 2002;346:645-652.
    • (2002) N Engl J Med , vol.346 , pp. 645-652
    • Kantarjian, H.1    Sawyers, C.2    Hochhaus, A.3
  • 33
    • 0037085785 scopus 로고    scopus 로고
    • Imatinib induces durable hematologic and cytogenetic responses in patients with accelerated phase chronic myeloid leukemia: Results of a phase 2 study
    • Talpaz M, Silver RT, Druker BJ, et al. Imatinib induces durable hematologic and cytogenetic responses in patients with accelerated phase chronic myeloid leukemia: results of a phase 2 study. Blood. 2002;99:1928-1937.
    • (2002) Blood , vol.99 , pp. 1928-1937
    • Talpaz, M.1    Silver, R.T.2    Druker, B.J.3
  • 34
    • 0037093092 scopus 로고    scopus 로고
    • Imatinib induces hematologic and cytogenetic responses in patients with chronic myelogenous leukemia in myeloid blast crisis: Results of a phase II study
    • Sawyers CL, Hochhaus A, Feldman E, et al. Imatinib induces hematologic and cytogenetic responses in patients with chronic myelogenous leukemia in myeloid blast crisis: results of a phase II study. Blood. 2002;99:3530-3539.
    • (2002) Blood , vol.99 , pp. 3530-3539
    • Sawyers, C.L.1    Hochhaus, A.2    Feldman, E.3
  • 35
    • 0035992329 scopus 로고    scopus 로고
    • Imatinib mesylate for Philadelphia chromosome-positive, chronic-phase myeloid leukemia after failure of interferon-alpha: Follow-up results
    • Kantarjian HM, Talpaz M, O'Brien S, et al. Imatinib mesylate for Philadelphia chromosome-positive, chronic-phase myeloid leukemia after failure of interferon-alpha: follow-up results. Clin Cancer Res. 2002;8:2177-2187.
    • (2002) Clin Cancer Res , vol.8 , pp. 2177-2187
    • Kantarjian, H.M.1    Talpaz, M.2    O'Brien, S.3
  • 36
    • 0035992318 scopus 로고    scopus 로고
    • Treatment of Philadelphia chromosome-positive, accelerated-phase chronic myelogenous leukemia with imatinib mesylate
    • Kantarjian HM, O'Brien S, Cortes JE, et al. Treatment of Philadelphia chromosome-positive, accelerated-phase chronic myelogenous leukemia with imatinib mesylate. Clin Cancer Res. 2002;8:2167-2176.
    • (2002) Clin Cancer Res , vol.8 , pp. 2167-2176
    • Kantarjian, H.M.1    O'Brien, S.2    Cortes, J.E.3
  • 37
    • 10744233716 scopus 로고    scopus 로고
    • Imatinib compared with interferon and low-dose cytarabine for newly diagnosed chronic-phase chronic myeloid leukemia
    • O'Brien SG, Guilhot F, Larson RA, et al. Imatinib compared with interferon and low-dose cytarabine for newly diagnosed chronic-phase chronic myeloid leukemia. N Engl J Med. 2003;348:994-1004.
    • (2003) N Engl J Med , vol.348 , pp. 994-1004
    • O'Brien, S.G.1    Guilhot, F.2    Larson, R.A.3
  • 38
    • 0037222235 scopus 로고    scopus 로고
    • Imatinib mesylate therapy in newly diagnosed patients with Philadelphia chromosome-positive chronic myelogenous leukemia: High incidence of early complete and major cytogenetic responses
    • Kantarjian HM, Cortes JE, O'Brien S, et al. Imatinib mesylate therapy in newly diagnosed patients with Philadelphia chromosome-positive chronic myelogenous leukemia: high incidence of early complete and major cytogenetic responses. Blood. 2003;101:97-100.
    • (2003) Blood , vol.101 , pp. 97-100
    • Kantarjian, H.M.1    Cortes, J.E.2    O'Brien, S.3
  • 39
    • 0035810142 scopus 로고    scopus 로고
    • Activity of a specific inhibitor of the BCR-ABL tyrosine kinase in the blast crisis of chronic myeloid leukemia and acute lymphoblastic leukemia with the Philadelphia chromosome
    • Druker BJ, Sawyers CL, Kantarjian H, et al. Activity of a specific inhibitor of the BCR-ABL tyrosine kinase in the blast crisis of chronic myeloid leukemia and acute lymphoblastic leukemia with the Philadelphia chromosome. N Engl J Med. 2001;344:1038-1042.
    • (2001) N Engl J Med , vol.344 , pp. 1038-1042
    • Druker, B.J.1    Sawyers, C.L.2    Kantarjian, H.3
  • 40
    • 0037105560 scopus 로고    scopus 로고
    • A phase 2 study of imatinib in patients with relapsed or refractory Philadelphia chromosome-positive acute lymphoid leukemias
    • Ottmann OG, Druker BJ, Sawyers CL, et al. A phase 2 study of imatinib in patients with relapsed or refractory Philadelphia chromosome-positive acute lymphoid leukemias. Blood. 2002;100:1965-1971.
    • (2002) Blood , vol.100 , pp. 1965-1971
    • Ottmann, O.G.1    Druker, B.J.2    Sawyers, C.L.3
  • 41
    • 0036940238 scopus 로고    scopus 로고
    • Therapy with imatinib mesylate (Glivec) preceding allogeneic stem cell transplantation (SCT) in relapsed or refractory Philadelphia-positive acute lymphoblastic leukemia (Ph+ALL)
    • Wassmann B, Pfeifer H, Scheuring U, et al. Therapy with imatinib mesylate (Glivec) preceding allogeneic stem cell transplantation (SCT) in relapsed or refractory Philadelphia-positive acute lymphoblastic leukemia (Ph+ALL). Leukemia. 2002;16:2358-2365.
    • (2002) Leukemia , vol.16 , pp. 2358-2365
    • Wassmann, B.1    Pfeifer, H.2    Scheuring, U.3
  • 42
    • 0035800507 scopus 로고    scopus 로고
    • Clinical resistance to STI-571 cancer therapy caused by BCR-ABL gene mutation or amplification
    • Gorre ME, Mohammed M, Ellwood K, et al. Clinical resistance to STI-571 cancer therapy caused by BCR-ABL gene mutation or amplification. Science 2001;293:876-880.
    • (2001) Science , vol.293 , pp. 876-880
    • Gorre, M.E.1    Mohammed, M.2    Ellwood, K.3
  • 43
    • 0038156170 scopus 로고    scopus 로고
    • Presence of the BCR-ABL mutation Glu255Lys prior to STI571 (imatinib) treatment in patients with Ph+ acute lymphoblastic leukemia
    • Hofmann WK, Komor M, Wassmann B, et al. Presence of the BCR-ABL mutation Glu255Lys prior to STI571 (imatinib) treatment in patients with Ph+ acute lymphoblastic leukemia. Blood. 2003;102;659-661.
    • (2003) Blood , vol.102 , pp. 659-661
    • Hofmann, W.K.1    Komor, M.2    Wassmann, B.3
  • 44
    • 0038700985 scopus 로고    scopus 로고
    • Imatinib mesylate in combination with other chemotherapeutic drugs: In vitro studies
    • Tipping AJ, Melo JV. Imatinib mesylate in combination with other chemotherapeutic drugs: in vitro studies. Semin Hematol. 2003;40(suppl 3):83-91.
    • (2003) Semin Hematol , vol.40 , Issue.SUPPL. 3 , pp. 83-91
    • Tipping, A.J.1    Melo, J.V.2
  • 45
    • 0242361680 scopus 로고    scopus 로고
    • Determination of drug synergism between the tyrosine kinase inhibitors NSC 680410 (adaphostin) and/or STI571 (imatinib mesylate, Gleevec) with cytotoxic drugs against human leukemia cell lines
    • Avramis IA, Laug WE, Sausville EA, Avramis VI. Determination of drug synergism between the tyrosine kinase inhibitors NSC 680410 (adaphostin) and/or STI571 (imatinib mesylate, Gleevec) with cytotoxic drugs against human leukemia cell lines. Cancer Chemother Pharmacol. 2003;52:307-318.
    • (2003) Cancer Chemother Pharmacol , vol.52 , pp. 307-318
    • Avramis, I.A.1    Laug, W.E.2    Sausville, E.A.3    Avramis, V.I.4
  • 46
    • 0033964380 scopus 로고    scopus 로고
    • Results of treatment with hyper-CVAD, a dose-intensive regimen, in adult acute lymphocytic leukemia
    • Kantarjian HM, O'Brien S, Smith TL, et al. Results of treatment with hyper-CVAD, a dose-intensive regimen, in adult acute lymphocytic leukemia. J Clin Oncol. 2000;18:547-561.
    • (2000) J Clin Oncol , vol.18 , pp. 547-561
    • Kantarjian, H.M.1    O'Brien, S.2    Smith, T.L.3
  • 47
    • 0029135378 scopus 로고
    • The value of high-dose systemic chemotherapy and intrathecal therapy for central nervous system prophylaxis in different risk groups of adult acute lymphoblastic leukemia
    • Cortes J, O'Brien SM, Pierce S, et al. The value of high-dose systemic chemotherapy and intrathecal therapy for central nervous system prophylaxis in different risk groups of adult acute lymphoblastic leukemia. Blood. 1995;86:2091-2097.
    • (1995) Blood , vol.86 , pp. 2091-2097
    • Cortes, J.1    O'Brien, S.M.2    Pierce, S.3
  • 48
    • 0028813711 scopus 로고
    • Prolonged survival in chronic myelogenous leukemia after cytogenetic response to interferon-alpha therapy
    • Kantarjian HM, Smith TL, O'Brien S, et al. Prolonged survival in chronic myelogenous leukemia after cytogenetic response to interferon-alpha therapy. Ann Intern Med. 1995;122:254-261.
    • (1995) Ann Intern Med , vol.122 , pp. 254-261
    • Kantarjian, H.M.1    Smith, T.L.2    O'Brien, S.3
  • 49
    • 0346756405 scopus 로고    scopus 로고
    • Quantitative polymerase chain reaction monitoring of BCR-ABL during therapy with imatinib mesylate (STI571; Gleevec) in chronic-phase chronic myelogenous leukemia
    • Kantarjian HM, Talpaz M, Cortes J, et al. Quantitative polymerase chain reaction monitoring of BCR-ABL during therapy with imatinib mesylate (STI571; Gleevec) in chronic-phase chronic myelogenous leukemia. Clin Cancer Res. 2003;9:160-166.
    • (2003) Clin Cancer Res , vol.9 , pp. 160-166
    • Kantarjian, H.M.1    Talpaz, M.2    Cortes, J.3
  • 50
    • 0025333497 scopus 로고
    • Results of the vincristine, doxorubicin, and dexamethasone regimen in adults with standard- and high-risk acute lymphocytic leukemia
    • Kantarjian HM, Walters RS, Keating MJ, et al. Results of the vincristine, doxorubicin, and dexamethasone regimen in adults with standard- and high-risk acute lymphocytic leukemia. J Clin Oncol 1990;8:994-1004.
    • (1990) J Clin Oncol , vol.8 , pp. 994-1004
    • Kantarjian, H.M.1    Walters, R.S.2    Keating, M.J.3
  • 51
    • 0012483654 scopus 로고    scopus 로고
    • The modified hyper-CVAD regimen in newly diagnosed adult acute lymphoblastic leukemia (ALL)
    • Abstract no. 2474
    • Thomas DA, Cortes J, Giles FJ, et al. The modified hyper-CVAD regimen in newly diagnosed adult acute lymphoblastic leukemia (ALL) [abstract]. Blood 2001;98(suppl 1):590a. Abstract no. 2474.
    • (2001) Blood , vol.98 , Issue.SUPPL. 1
    • Thomas, D.A.1    Cortes, J.2    Giles, F.J.3
  • 52
    • 0000336139 scopus 로고
    • Regression models and life tables
    • Cox DR. Regression models and life tables. J R Stat Soc [B]. 1972;34:187-220.
    • (1972) J R Stat Soc [B] , vol.34 , pp. 187-220
    • Cox, D.R.1
  • 53
    • 33845382806 scopus 로고
    • Non-parametric estimation form incomplete observations
    • Kaplan EL, Meier P. Non-parametric estimation form incomplete observations. J Am Stat Assoc. 1965;53:457-481.
    • (1965) J Am Stat Assoc , vol.53 , pp. 457-481
    • Kaplan, E.L.1    Meier, P.2
  • 54
    • 0024317523 scopus 로고
    • Six-year follow-up of the clinical significance of karyotype in acute lymphoblastic leukemia
    • Bloomfield CD, Secker-Walker LM, Goldman AI, et al. Six-year follow-up of the clinical significance of karyotype in acute lymphoblastic leukemia. Cancer Genet Cytogenet. 1989;40:171-185.
    • (1989) Cancer Genet Cytogenet , vol.40 , pp. 171-185
    • Bloomfield, C.D.1    Secker-Walker, L.M.2    Goldman, A.I.3
  • 55
    • 0026535624 scopus 로고
    • Clinical and prognostic significance of the Philadelphia chromosome in adult patients with acute lymphoblastic leukemia
    • Gotz G, Weh HJ, Walter TA, et al. Clinical and prognostic significance of the Philadelphia chromosome in adult patients with acute lymphoblastic leukemia. Ann Hematol. 1992;64:97-100.
    • (1992) Ann Hematol , vol.64 , pp. 97-100
    • Gotz, G.1    Weh, H.J.2    Walter, T.A.3
  • 56
    • 0027091627 scopus 로고
    • Clinical significance of the BCR-ABL fusion gene in adult acute lymphoblastic leukemia: A Cancer and Leukemia Group B Study
    • Westbrook CA, Hooberman AL, Spino C, et al. Clinical significance of the BCR-ABL fusion gene in adult acute lymphoblastic leukemia: a Cancer and Leukemia Group B Study. Blood. 1992;80:2983-2990.
    • (1992) Blood , vol.80 , pp. 2983-2990
    • Westbrook, C.A.1    Hooberman, A.L.2    Spino, C.3
  • 57
    • 0028938844 scopus 로고
    • A five-drug remission induction regimen with intensive consolidation for adults with acute lymphoblastic leukemia: Cancer and leukemia group B study 8811
    • Larson RA, Dodge RK, Burns CP, et al. A five-drug remission induction regimen with intensive consolidation for adults with acute lymphoblastic leukemia: cancer and leukemia group B study 8811. Blood. 1995;85:2025-2037.
    • (1995) Blood , vol.85 , pp. 2025-2037
    • Larson, R.A.1    Dodge, R.K.2    Burns, C.P.3
  • 58
    • 0029867127 scopus 로고    scopus 로고
    • Cytogenetic abnormalities in adult acute lymphoblastic leukemia: Correlations with hematologic findings outcome: A Collaborative Study of the Group Francais de Cytogenetique Hematologique
    • Group Francais de Cytogenetique Hematologique. Cytogenetic abnormalities in adult acute lymphoblastic leukemia: correlations with hematologic findings outcome: a Collaborative Study of the Group Francais de Cytogenetique Hematologique [erratum in: Blood 1996;88:2818]. Blood. 1996;87:3135-3142.
    • (1996) Blood , vol.87 , pp. 3135-3142
  • 59
    • 0029819426 scopus 로고    scopus 로고
    • Erratum
    • Group Francais de Cytogenetique Hematologique. Cytogenetic abnormalities in adult acute lymphoblastic leukemia: correlations with hematologic findings outcome: a Collaborative Study of the Group Francais de Cytogenetique Hematologique [erratum in: Blood 1996;88:2818]. Blood. 1996;87:3135-3142.
    • (1996) Blood , vol.88 , pp. 2818
  • 60
    • 0030885478 scopus 로고    scopus 로고
    • Improved treatment outcome in adult acute lymphoblastic leukemia using the intensive German protocol, a preliminary report
    • Chim CS, Kwong YL, Chu YC, et al. Improved treatment outcome in adult acute lymphoblastic leukemia using the intensive German protocol, a preliminary report. Hematol Oncol. 1997;15:19-26.
    • (1997) Hematol Oncol , vol.15 , pp. 19-26
    • Chim, C.S.1    Kwong, Y.L.2    Chu, Y.C.3
  • 61
    • 0031034526 scopus 로고    scopus 로고
    • Cytogenetics adds independent prognostic information in adults with acute lymphoblastic leukaemia on MRC trial UKALL XA: MRC Adult Leukaemia Working Party
    • Secker-Walker LM, Prentice HG, Durrant J, et al. Cytogenetics adds independent prognostic information in adults with acute lymphoblastic leukaemia on MRC trial UKALL XA: MRC Adult Leukaemia Working Party. Br J Haematol. 1997;96:601-610.
    • (1997) Br J Haematol , vol.96 , pp. 601-610
    • Secker-Walker, L.M.1    Prentice, H.G.2    Durrant, J.3
  • 62
    • 0031841173 scopus 로고    scopus 로고
    • Philadelphia chromosome postitive adult acute lymphoblastic leukemia: Characteristics, prognostic factors and treatment outcome
    • Thomas X, Thiebaut A, Olteanu N, et al. Philadelphia chromosome postitive adult acute lymphoblastic leukemia: characteristics, prognostic factors and treatment outcome. Hematol Cell Ther. 1998;40:119-128.
    • (1998) Hematol Cell Ther , vol.40 , pp. 119-128
    • Thomas, X.1    Thiebaut, A.2    Olteanu, N.3
  • 63
    • 0033153105 scopus 로고    scopus 로고
    • Prospective karyotype analysis in adult acute lymphoblastic leukemia: The cancer and leukemia Group B experience
    • Wetzler M, Dodge RK, Mrozek K, et al. Prospective karyotype analysis in adult acute lymphoblastic leukemia: The cancer and leukemia Group B experience. Blood. 1999;93:3983-3993.
    • (1999) Blood , vol.93 , pp. 3983-3993
    • Wetzler, M.1    Dodge, R.K.2    Mrozek, K.3
  • 64
    • 0034794596 scopus 로고    scopus 로고
    • Philadelphia chromosome-positive acute lymphoblastic leukemia in Taiwan
    • Ko BS, Tang JL, Tsai W, et al. Philadelphia chromosome-positive acute lymphoblastic leukemia in Taiwan. Ann Hematol. 2001;80:510-515.
    • (2001) Ann Hematol , vol.80 , pp. 510-515
    • Ko, B.S.1    Tang, J.L.2    Tsai, W.3
  • 65
    • 0035203227 scopus 로고    scopus 로고
    • Long-term follow-up of patients with newly diagnosed adult acute lymphoblastic leukemia: A single institution experience of 378 consecutive patients over a 21-year period
    • Thomas X, Danaila C, Le QH, et al. Long-term follow-up of patients with newly diagnosed adult acute lymphoblastic leukemia: A single institution experience of 378 consecutive patients over a 21-year period. Leukemia. 2001;15:1811-1822.
    • (2001) Leukemia , vol.15 , pp. 1811-1822
    • Thomas, X.1    Danaila, C.2    Le, Q.H.3
  • 66
    • 0036464686 scopus 로고    scopus 로고
    • Treatment of adult acute lymphoblastic leukemia (ALL): Long-term follow-up of the GIMEMA ALL 0288 randomized study
    • Annino L, Vegna ML, Camera A, et al. Treatment of adult acute lymphoblastic leukemia (ALL): long-term follow-up of the GIMEMA ALL 0288 randomized study. Blood. 2002;99:863-871.
    • (2002) Blood , vol.99 , pp. 863-871
    • Annino, L.1    Vegna, M.L.2    Camera, A.3
  • 67
    • 0036786909 scopus 로고    scopus 로고
    • Outcome of treatment in adults with Philadelphia chromosome-positive acute lymphoblastic leukemia-results of the prospective multicenter LALA-94 trial
    • Dombret H, Gabert J, Boiron JM, et al. Outcome of treatment in adults with Philadelphia chromosome-positive acute lymphoblastic leukemia-results of the prospective multicenter LALA-94 trial. Blood. 2002;100:2357-2366.
    • (2002) Blood , vol.100 , pp. 2357-2366
    • Dombret, H.1    Gabert, J.2    Boiron, J.M.3
  • 68
    • 0028826490 scopus 로고
    • Bone marrow transplantation for Philadelphia-chromosome-positive acute lymphoblastic leukemia
    • Stockschlader M, Hegewisch-Becker S, Kruger W, et al. Bone marrow transplantation for Philadelphia-chromosome-positive acute lymphoblastic leukemia. Bone Marrow Transplant. 1995;16:663-667.
    • (1995) Bone Marrow Transplant , vol.16 , pp. 663-667
    • Stockschlader, M.1    Hegewisch-Becker, S.2    Kruger, W.3
  • 69
    • 0030749222 scopus 로고    scopus 로고
    • Marrow transplants from unrelated donors for treatment of Philadelphia chromosome-positive acute lymphoblastic leukemia
    • Sierra J, Radich J, Hansen JA, et al. Marrow transplants from unrelated donors for treatment of Philadelphia chromosome-positive acute lymphoblastic leukemia. Blood. 1997;90:1410-1414.
    • (1997) Blood , vol.90 , pp. 1410-1414
    • Sierra, J.1    Radich, J.2    Hansen, J.A.3
  • 70
    • 0009996654 scopus 로고    scopus 로고
    • Allogeneic transplant (related or unrelated donor) is the preferred treatment for adult Philadelphia chromosome positive (Ph+) acute lymphoblastic leukaemia (ALL): Results from the International ALLTrial (MRC UKALLXII/ECOG E2993)
    • Goldstone AH, Prentice HG, Durrant IJ, et al. Allogeneic transplant (related or unrelated donor) is the preferred treatment for adult Philadelphia chromosome positive (Ph+) acute lymphoblastic leukaemia (ALL): Results from the International ALLTrial (MRC UKALLXII/ECOG E2993) [abstract]. Blood. 2001;98:856a.
    • (2001) Blood , vol.98
    • Goldstone, A.H.1    Prentice, H.G.2    Durrant, I.J.3
  • 71
    • 0035869381 scopus 로고    scopus 로고
    • Unrelated marrow transplantation for adult patients with poor-risk acute lymphoblastic leukemia: Strong graft-versus-leukemia effect and risk factors determining outcome
    • Cornelissen JJ, Carston M, Kollman C, et al. Unrelated marrow transplantation for adult patients with poor-risk acute lymphoblastic leukemia: strong graft-versus-leukemia effect and risk factors determining outcome. Blood. 2001;97:1572-1577.
    • (2001) Blood , vol.97 , pp. 1572-1577
    • Cornelissen, J.J.1    Carston, M.2    Kollman, C.3
  • 72
    • 0037217606 scopus 로고    scopus 로고
    • Risk factors for adults with Philadelphia-chromosome-positive acute lymphoblastic leukaemia in remission treated with allogeneic bone marrow transplantation: The potential of real-time quantitative reverse-transcription polymerase chain reaction
    • Lee S, Kim DW, Cho B, et al. Risk factors for adults with Philadelphia-chromosome-positive acute lymphoblastic leukaemia in remission treated with allogeneic bone marrow transplantation: The potential of real-time quantitative reverse-transcription polymerase chain reaction. Br J Haematol. 2003;120:145-153.
    • (2003) Br J Haematol , vol.120 , pp. 145-153
    • Lee, S.1    Kim, D.W.2    Cho, B.3
  • 73
    • 0035205062 scopus 로고    scopus 로고
    • Prospective BCR-ABL analysis by polymerase chain reaction (RT-PCR) in adult acute B-lineage lymphoblastic leukemia: Reliability of RT-nested-PCR and comparison to cytogenetic data
    • Gleissner B, Rieder H, Thiel E, et al. Prospective BCR-ABL analysis by polymerase chain reaction (RT-PCR) in adult acute B-lineage lymphoblastic leukemia: Reliability of RT-nested-PCR and comparison to cytogenetic data. Leukemia. 2001;15:1834-1840.
    • (2001) Leukemia , vol.15 , pp. 1834-1840
    • Gleissner, B.1    Rieder, H.2    Thiel, E.3
  • 74
    • 0036009610 scopus 로고    scopus 로고
    • Molecular measurement of minimal residual disease in Philadelphia-positive acute lymphoblastic leukaemia
    • Radich JP. Molecular measurement of minimal residual disease in Philadelphia-positive acute lymphoblastic leukaemia. Best Pract Res Clin Haematol. 2002;15:91-103.
    • (2002) Best Pract Res Clin Haematol , vol.15 , pp. 91-103
    • Radich, J.P.1
  • 75
    • 0242367154 scopus 로고    scopus 로고
    • Predictors of relapse and overall survival in Philadelphia chromosome-positive acute lymphoblastic leukemia after transplantation
    • Stirewalt DL, Guthrie KA, Beppu L, et al. Predictors of relapse and overall survival in Philadelphia chromosome-positive acute lymphoblastic leukemia after transplantation. Biol Blood Marrow Transplant. 2003;9:206-212.
    • (2003) Biol Blood Marrow Transplant , vol.9 , pp. 206-212
    • Stirewalt, D.L.1    Guthrie, K.A.2    Beppu, L.3
  • 76
    • 0037220339 scopus 로고    scopus 로고
    • Early minimal residual disease (MRD) analysis during treatment of Philadelphia chromosome/Bcr-Abl-positive acute lymphoblastic leukemia with the Abl-tyrosine kinase inhibitor imatinib (STI571)
    • Scheuring UJ, Pfeifer H, Wassmann B, et al. Early minimal residual disease (MRD) analysis during treatment of Philadelphia chromosome/Bcr-Abl-positive acute lymphoblastic leukemia with the Abl-tyrosine kinase inhibitor imatinib (STI571). Blood. 2003;101:85-90.
    • (2003) Blood , vol.101 , pp. 85-90
    • Scheuring, U.J.1    Pfeifer, H.2    Wassmann, B.3
  • 77
    • 0032865769 scopus 로고    scopus 로고
    • Quantification of minimal residual disease in patients with BCR-ABL-positive acute lymphoblastic leukaemia using quantitative competitive polymerase chain reaction
    • Mitterbauer G, Nemeth P, Wacha S, et al. Quantification of minimal residual disease in patients with BCR-ABL-positive acute lymphoblastic leukaemia using quantitative competitive polymerase chain reaction. Br J Haematol. 1999;106:634-643.
    • (1999) Br J Haematol , vol.106 , pp. 634-643
    • Mitterbauer, G.1    Nemeth, P.2    Wacha, S.3
  • 78
    • 0037045589 scopus 로고    scopus 로고
    • Relation between resistance of Philadelphia-chromosome-positive acute lymphoblastic leukaemia to the tyrosine kinase inhibitor STI571 and gene-expression profiles: A gene-expression study
    • Hofmann WK, de Vos S, Elashoff D, et al. Relation between resistance of Philadelphia-chromosome-positive acute lymphoblastic leukaemia to the tyrosine kinase inhibitor STI571 and gene-expression profiles: a gene-expression study. Lancet. 2002;359:481-486.
    • (2002) Lancet , vol.359 , pp. 481-486
    • Hofmann, W.K.1    De Vos, S.2    Elashoff, D.3
  • 79
    • 0038721475 scopus 로고    scopus 로고
    • The CNS is a sanctuary for leukemic cells in mice receiving imatinib mesylate for Bcr/Abl-induced leukemia
    • Wolff NC, Richardson JA, Egorin M, Ilaria RL Jr. The CNS is a sanctuary for leukemic cells in mice receiving imatinib mesylate for Bcr/Abl-induced leukemia. Blood. 2003;101:5010-5013.
    • (2003) Blood , vol.101 , pp. 5010-5013
    • Wolff, N.C.1    Richardson, J.A.2    Egorin, M.3    Ilaria Jr., R.L.4
  • 80
    • 0036399992 scopus 로고    scopus 로고
    • Imatinib mesylate has limited activity against the central nervous system involvement of Philadelphia chromosome-positive acute lymphoblastic leukaemia due to poor penetration into cerebrospinal fluid
    • Takayama N, Sato N, O'Brien SG, et al. Imatinib mesylate has limited activity against the central nervous system involvement of Philadelphia chromosome-positive acute lymphoblastic leukaemia due to poor penetration into cerebrospinal fluid. Br J Haematol. 2002;119:106-108.
    • (2002) Br J Haematol , vol.119 , pp. 106-108
    • Takayama, N.1    Sato, N.2    O'Brien, S.G.3
  • 81
    • 0003285566 scopus 로고    scopus 로고
    • Combination of hyper-CVAD with imatinib mesylate (STI571) for Philadelphia (Ph)-positive adult acute lymphoblastic leukemia (ALL) or chronic myelogenous leukemia in lymphoid blast phase (CML-LBP)
    • Thomas DA, Cortes J, Giles FJ, et al. Combination of hyper-CVAD with imatinib mesylate (STI571) for Philadelphia (Ph)-positive adult acute lymphoblastic leukemia (ALL) or chronic myelogenous leukemia in lymphoid blast phase (CML-LBP). Blood. 2001;98:803a.
    • (2001) Blood , vol.98
    • Thomas, D.A.1    Cortes, J.2    Giles, F.J.3
  • 82
    • 0037752340 scopus 로고    scopus 로고
    • Minimal residual disease (MRD) after hyper-CVAD and imatinib mesylate (STI571) for Philadelphia (Ph) positive adult acute lymphoblastic leukemia (ALL)
    • Thomas DA, Cortes J, Garcia-Manero G, et al. Minimal residual disease (MRD) after hyper-CVAD and imatinib mesylate (STI571) for Philadelphia (Ph) positive adult acute lymphoblastic leukemia (ALL). Blood. 2002;100:764a.
    • (2002) Blood , vol.100
    • Thomas, D.A.1    Cortes, J.2    Garcia-Manero, G.3
  • 83
    • 1542322129 scopus 로고    scopus 로고
    • Results of intensive chemotherapy with hyper-CVAD and imatinib mesylate in Philadelphia (Ph) positive acute lymphocytic leukemia (ALL)
    • Thomas DA, Garcia-Manero G, Cortes J, et al. Results of intensive chemotherapy with hyper-CVAD and imatinib mesylate in Philadelphia (Ph) positive acute lymphocytic leukemia (ALL). Proc Am Soc Clin Oncol. 2003;22:588.
    • (2003) Proc Am Soc Clin Oncol , vol.22 , pp. 588
    • Thomas, D.A.1    Garcia-Manero, G.2    Cortes, J.3


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