메뉴 건너뛰기




Volumn 11, Issue 11, 2013, Pages 1327-1340

Chronic myelogenous leukemia, version 1.2014: Featured updates to the NCCN guidelines

(23)  O'Brien, Susan a   Radich, Jerald P b   Abboud, Camille N c   Akhtari, Mojtaba d   Altman, Jessica K e   Berman, Ellin f   DeAngelo, Daniel J g   Deininger, Michael h   Devine, Steven i   Fathi, Amir T j   Gotlib, Jason k   Jagasia, Madan l   Kropf, Patricia m   Moore, Joseph O n   Pallera, Arnel o   Pinilla Ibarz, Javier p   Reddy, Vishnu V B q   Shah, Neil P r   Douglas Smith, B s   Snyder, David S t   more..


Author keywords

[No Author keywords available]

Indexed keywords

BCR ABL PROTEIN; DASATINIB; IMATINIB; MESSENGER RNA; NILOTINIB; PONATINIB; PROTEIN TYROSINE KINASE INHIBITOR;

EID: 84891954191     PISSN: 15401405     EISSN: 15401413     Source Type: Journal    
DOI: 10.6004/jnccn.2013.0157     Document Type: Review
Times cited : (55)

References (48)
  • 2
    • 70349575806 scopus 로고    scopus 로고
    • Chronic myeloid leukemia (CML) with P190 BCR-ABL: Analysis of characteristics, outcomes, and prognostic significance
    • Verma D, Kantarjian HM, Jones D, et al. Chronic myeloid leukemia (CML) with P190 BCR-ABL: analysis of characteristics, outcomes, and prognostic significance. Blood 2009;114:2232-2235.
    • (2009) Blood , vol.114 , pp. 2232-2235
    • Verma, D.1    Kantarjian, H.M.2    Jones, D.3
  • 3
    • 77949767505 scopus 로고    scopus 로고
    • International randomized study of interferon vs STI571 (IRIS) 8-year follow up: Sustained survival and low risk for progression or events in patients with newly diagnosed chronic myeloid leukemia in chronic phase (CML-CP) treated with imatinib
    • [abstract]. Abstract 1126
    • Deininger M, O'Brien SG, Guilhot F, et al. International randomized study of interferon vs STI571 (IRIS) 8-year follow up: sustained survival and low risk for progression or events in patients with newly diagnosed chronic myeloid leukemia in chronic phase (CML-CP) treated with imatinib [abstract]. Blood 2009;114:Abstract 1126.
    • (2009) Blood , vol.114
    • Deininger, M.1    O'Brien, S.G.2    Guilhot, F.3
  • 4
    • 84871215155 scopus 로고    scopus 로고
    • Dasatinib versus imatinib (IM) in newly diagnosed chronic myeloid leukemia in chronic phase (CML-CP): DASISION 3-year follow-up
    • [abstract]. Abstract 6504
    • Hochhaus A, Shah NP, Cortes JE, et al. Dasatinib versus imatinib (IM) in newly diagnosed chronic myeloid leukemia in chronic phase (CML-CP): DASISION 3-year follow-up [abstract]. J Clin Oncol 2012;30(Suppl):Abstract 6504.
    • (2012) J Clin Oncol , vol.30 , Issue.SUPPL.
    • Hochhaus, A.1    Shah, N.P.2    Cortes, J.E.3
  • 5
    • 84867395848 scopus 로고    scopus 로고
    • Nilotinib vs imatinib in patients with newly diagnosed Philadelphia chromosome-positive chronic myeloid leukemia in chronic phase: ENESTnd 3-year follow-up
    • Larson RA, Hochhaus A, Hughes TP, et al. Nilotinib vs imatinib in patients with newly diagnosed Philadelphia chromosome-positive chronic myeloid leukemia in chronic phase: ENESTnd 3-year follow-up. Leukemia 2012;26:2197-2203.
    • (2012) Leukemia , vol.26 , pp. 2197-2203
    • Larson, R.A.1    Hochhaus, A.2    Hughes, T.P.3
  • 6
    • 76549116248 scopus 로고    scopus 로고
    • Potent, transient inhibition of BCR-ABL with dasatinib 100 mg daily achieves rapid and durable cytogenetic responses and high transformation-free survival rates in chronic phase chronic myeloid leukemia patients with resistance, suboptimal response or intolerance to imatinib
    • Shah NP, Kim D-W, Kantarjian H, et al. Potent, transient inhibition of BCR-ABL with dasatinib 100 mg daily achieves rapid and durable cytogenetic responses and high transformation-free survival rates in chronic phase chronic myeloid leukemia patients with resistance, suboptimal response or intolerance to imatinib. Haematologica 2010;95:232-240.
    • (2010) Haematologica , vol.95 , pp. 232-240
    • Shah, N.P.1    Kim, D.-W.2    Kantarjian, H.3
  • 7
    • 84871194036 scopus 로고    scopus 로고
    • Six-year (yr) follow-up of patients (pts) with imatinib-resistant or -intolerant chronic-phase chronic myeloid leukemia (CML-CP) receiving dasatinib
    • [abstract]. Abstract 6506
    • Shah NP, Kantarjian H, Kim DW, et al. Six-year (yr) follow-up of patients (pts) with imatinib-resistant or -intolerant chronic-phase chronic myeloid leukemia (CML-CP) receiving dasatinib [abstract]. J Clin Oncol 2012;30(Suppl):Abstract 6506.
    • (2012) J Clin Oncol , vol.30 , Issue.SUPPL.
    • Shah, N.P.1    Kantarjian, H.2    Kim, D.W.3
  • 8
    • 84873568081 scopus 로고    scopus 로고
    • Nilotinib in imatinib-resistant or imatinib-intolerant patients with chronic myeloid leukemia in chronic phase: 48-month follow-up results of a phase II study
    • Giles FJ, le Coutre PD, Pinilla-Ibarz J, et al. Nilotinib in imatinib-resistant or imatinib-intolerant patients with chronic myeloid leukemia in chronic phase: 48-month follow-up results of a phase II study. Leukemia 2013;27:107-112.
    • (2013) Leukemia , vol.27 , pp. 107-112
    • Giles, F.J.1    Le Coutre, P.D.2    Pinilla-Ibarz, J.3
  • 9
    • 84859836481 scopus 로고    scopus 로고
    • Bosutinib is active in chronic phase chronic myeloid leukemia after imatinib and dasatinib and/or nilotinib therapy failure
    • Khoury HJ, Cortes JE, Kantarjian HM, et al. Bosutinib is active in chronic phase chronic myeloid leukemia after imatinib and dasatinib and/or nilotinib therapy failure. Blood 2012;119:3403-3412.
    • (2012) Blood , vol.119 , pp. 3403-3412
    • Khoury, H.J.1    Cortes, J.E.2    Kantarjian, H.M.3
  • 10
    • 84877096203 scopus 로고    scopus 로고
    • A pivotal phase 2 trial of ponatinib in patients with chronic myeloid leukemia (CML) and Philadelphia chromosome-positive acute lymphoblastic leukemia (Ph+ALL) resistant or intolerant to dasatinib or nilotinib, or with the T315I BCR-ABL mutation: 12-month follow-up of the PACE trial
    • [abstract]. Abstract 163
    • Cortes JE, Kim DW, Pinilla-Ibarz J, et al. A pivotal phase 2 trial of ponatinib in patients with chronic myeloid leukemia (CML) and Philadelphia chromosome-positive acute lymphoblastic leukemia (Ph+ALL) resistant or intolerant to dasatinib or nilotinib, or with the T315I BCR-ABL mutation: 12-month follow-up of the PACE trial [abstract]. Blood 2012;120:Abstract 163.
    • (2012) Blood , vol.120
    • Cortes, J.E.1    Kim, D.W.2    Pinilla-Ibarz, J.3
  • 11
    • 0346756405 scopus 로고    scopus 로고
    • Quantitative polymerase chain reaction monitoring of BCR-ABL during therapy with imatinib mesylate (STI571; Gleevec) in chronic-phase chronic myelogenous leukemia
    • Kantarjian HM, Talpaz M, Cortes J, et al. Quantitative polymerase chain reaction monitoring of BCR-ABL during therapy with imatinib mesylate (STI571; Gleevec) in chronic-phase chronic myelogenous leukemia. Clin Cancer Res 2003;9:160-166.
    • (2003) Clin Cancer Res , vol.9 , pp. 160-166
    • Kantarjian, H.M.1    Talpaz, M.2    Cortes, J.3
  • 12
    • 33745603988 scopus 로고    scopus 로고
    • Monitoring CML patients responding to treatment with tyrosine kinase inhibitors: Review and recommendations for harmonizing current methodology for detecting BCR-ABL transcripts and kinase domain mutations and for expressing results
    • Hughes T, Deininger M, Hochhaus A, et al. Monitoring CML patients responding to treatment with tyrosine kinase inhibitors: review and recommendations for harmonizing current methodology for detecting BCR-ABL transcripts and kinase domain mutations and for expressing results. Blood 2006;108:28-37.
    • (2006) Blood , vol.108 , pp. 28-37
    • Hughes, T.1    Deininger, M.2    Hochhaus, A.3
  • 13
    • 10744229080 scopus 로고    scopus 로고
    • Frequency of major molecular responses to imatinib or interferon alfa plus cytarabine in newly diagnosed chronic myeloid leukemia
    • Hughes T, Kaeda J, Branford S, et al. Frequency of major molecular responses to imatinib or interferon alfa plus cytarabine in newly diagnosed chronic myeloid leukemia. N Engl J Med 2003;349:1423-1432.
    • (2003) N Engl J Med , vol.349 , pp. 1423-1432
    • Hughes, T.1    Kaeda, J.2    Branford, S.3
  • 14
    • 9144271651 scopus 로고    scopus 로고
    • Evaluation of candidate control genes for diagnosis and residual disease detection in leukemic patients using 'real-time' quantitative reverse-transcriptase polymerase chain reaction (RQ-PCR): A Europe Against Cancer program
    • Beillard E, Pallisgaard N, van der Velden VH, et al. Evaluation of candidate control genes for diagnosis and residual disease detection in leukemic patients using 'real-time' quantitative reverse-transcriptase polymerase chain reaction (RQ-PCR): a Europe Against Cancer program. Leukemia 2003;17:2474-2486.
    • (2003) Leukemia , vol.17 , pp. 2474-2486
    • Beillard, E.1    Pallisgaard, N.2    Van Der Velden, V.H.3
  • 15
    • 20944442975 scopus 로고    scopus 로고
    • Molecular responses in patients with chronic myelogenous leukemia in chronic phase treated with imatinib mesylate
    • Cortes J, Talpaz M, O'Brien S, et al. Molecular responses in patients with chronic myelogenous leukemia in chronic phase treated with imatinib mesylate. Clin Cancer Res 2005;11:3425-3432.
    • (2005) Clin Cancer Res , vol.11 , pp. 3425-3432
    • Cortes, J.1    Talpaz, M.2    O'Brien, S.3
  • 16
    • 33750327903 scopus 로고    scopus 로고
    • Rationale for the recommendations for harmonizing current methodology for detecting BCR-ABL transcripts in patients with chronic myeloid leukaemia
    • Branford S, Cross NCP, Hochhaus A, et al. Rationale for the recommendations for harmonizing current methodology for detecting BCR-ABL transcripts in patients with chronic myeloid leukaemia. Leukemia 2006;20:1925-1930.
    • (2006) Leukemia , vol.20 , pp. 1925-1930
    • Branford, S.1    Cross, N.C.P.2    Hochhaus, A.3
  • 17
    • 71849110507 scopus 로고    scopus 로고
    • Standardisation of molecular monitoring for chronic myeloid leukaemia
    • Cross NC. Standardisation of molecular monitoring for chronic myeloid leukaemia. Best Pract Res Clin Haematol 2009;22:355-365.
    • (2009) Best Pract Res Clin Haematol , vol.22 , pp. 355-365
    • Cross, N.C.1
  • 18
    • 54049139246 scopus 로고    scopus 로고
    • Desirable performance characteristics for BCR-ABL measurement on an international reporting scale to allow consistent interpretation of individual patient response and comparison of response rates between clinical trials
    • Branford S, Fletcher L, Cross NC, et al. Desirable performance characteristics for BCR-ABL measurement on an international reporting scale to allow consistent interpretation of individual patient response and comparison of response rates between clinical trials. Blood 2008;112:3330-3338.
    • (2008) Blood , vol.112 , pp. 3330-3338
    • Branford, S.1    Fletcher, L.2    Cross, N.C.3
  • 19
    • 84868552615 scopus 로고    scopus 로고
    • A randomized trial of dasatinib 100 mg vs imatinib 400 mg in newly diagnosed chronic phase chromic myeloid leukemia
    • Radich JP, Kopecky KJ, Appelbaum FR, et al. A randomized trial of dasatinib 100 mg vs imatinib 400 mg in newly diagnosed chronic phase chromic myeloid leukemia. Blood 2012;120:3898-3905.
    • (2012) Blood , vol.120 , pp. 3898-3905
    • Radich, J.P.1    Kopecky, K.J.2    Appelbaum, F.R.3
  • 20
    • 73949105873 scopus 로고    scopus 로고
    • Dasatinib treatment of chronic-phase chronic myeloid leukemia: Analysis of responses according to preexisting BCR-ABL mutations
    • Muller MC, Cortes JE, Kim D-W, et al. Dasatinib treatment of chronic-phase chronic myeloid leukemia: analysis of responses according to preexisting BCR-ABL mutations. Blood 2009;114:4944-4953.
    • (2009) Blood , vol.114 , pp. 4944-4953
    • Muller, M.C.1    Cortes, J.E.2    Kim, D.-W.3
  • 21
    • 70249105789 scopus 로고    scopus 로고
    • Impact of baseline BCR-ABL mutations on response to nilotinib in patients with chronic myeloid leukemia in chronic phase
    • Hughes T, Saglio G, Branford S, et al. Impact of baseline BCR-ABL mutations on response to nilotinib in patients with chronic myeloid leukemia in chronic phase. J Clin Oncol 2009;27:4204-4210.
    • (2009) J Clin Oncol , vol.27 , pp. 4204-4210
    • Hughes, T.1    Saglio, G.2    Branford, S.3
  • 22
    • 84883775862 scopus 로고    scopus 로고
    • Molecular responses with ponatinib in patients with Philadelphia chromosome positive (Ph+) leukemia: Results from the PACE trial
    • [abstract]. Abstract 3763
    • Hochhaus A, Kim D-W, Pinilla-Ibarz J, et al. Molecular responses with ponatinib in patients with Philadelphia chromosome positive (Ph+) leukemia: results from the PACE trial [abstract]. Blood 2012;120:Abstract 3763.
    • (2012) Blood , vol.120
    • Hochhaus, A.1    Kim, D.-W.2    Pinilla-Ibarz, J.3
  • 23
    • 84891917140 scopus 로고    scopus 로고
    • Impact of baseline mutations on response to ponatinib and end of treatment mutation analysis in patients with chronic myeloid leukemia
    • [abstract]. Abstract 7001
    • Deininger MWN, Cortes JE, Kim DW, et al. Impact of baseline mutations on response to ponatinib and end of treatment mutation analysis in patients with chronic myeloid leukemia [abstract]. J Clin Oncol 2013;31(Suppl):Abstract 7001.
    • (2013) J Clin Oncol , vol.31 , Issue.SUPPL.
    • Deininger, M.W.N.1    Cortes, J.E.2    Kim, D.W.3
  • 24
    • 79955400117 scopus 로고    scopus 로고
    • Practical advice for determining the role of BCR-ABL mutations in guiding tyrosine kinase inhibitor therapy in patients with chronic myeloid leukemia
    • Jabbour E, Branford S, Saglio G, et al. Practical advice for determining the role of BCR-ABL mutations in guiding tyrosine kinase inhibitor therapy in patients with chronic myeloid leukemia. Cancer 2011;117:1800-1811.
    • (2011) Cancer , vol.117 , pp. 1800-1811
    • Jabbour, E.1    Branford, S.2    Saglio, G.3
  • 25
    • 80051573352 scopus 로고    scopus 로고
    • BCR-ABL kinase domain mutation analysis in chronic myeloid leukemia patients treated with tyrosine kinase inhibitors: Recommendations from an expert panel on behalf of European LeukemiaNet
    • Soverini S, Hochhaus A, Nicolini FE, et al. BCR-ABL kinase domain mutation analysis in chronic myeloid leukemia patients treated with tyrosine kinase inhibitors: recommendations from an expert panel on behalf of European LeukemiaNet. Blood 2011;118:1208-1215.
    • (2011) Blood , vol.118 , pp. 1208-1215
    • Soverini, S.1    Hochhaus, A.2    Nicolini, F.E.3
  • 26
    • 20844447330 scopus 로고    scopus 로고
    • Real-time quantitative PCR analysis can be used as a primary screen to identify patients with CML treated with imatinib who have BCR-ABL kinase domain mutations
    • Branford S, Rudzki Z, Parkinson I, et al. Real-time quantitative PCR analysis can be used as a primary screen to identify patients with CML treated with imatinib who have BCR-ABL kinase domain mutations. Blood 2004;104:2926-2932.
    • (2004) Blood , vol.104 , pp. 2926-2932
    • Branford, S.1    Rudzki, Z.2    Parkinson, I.3
  • 27
    • 33644516935 scopus 로고    scopus 로고
    • The role of serial BCR-ABL transcript monitoring in predicting the emergence of BCR-ABL kinase mutations in imatinib-treated patients with chronic myeloid leukemia
    • Wang L, Knight K, Lucas C, Clark R. The role of serial BCR-ABL transcript monitoring in predicting the emergence of BCR-ABL kinase mutations in imatinib-treated patients with chronic myeloid leukemia. Haematologica 2006;91:235-239.
    • (2006) Haematologica , vol.91 , pp. 235-239
    • Wang, L.1    Knight, K.2    Lucas, C.3    Clark, R.4
  • 28
    • 68949108481 scopus 로고    scopus 로고
    • Significance of increasing levels of minimal residual disease in patients with Philadelphia chromosome-positive chronic myelogenous leukemia in complete cytogenetic response
    • Kantarjian HM, Shan J, Jones D, et al. Significance of increasing levels of minimal residual disease in patients with Philadelphia chromosome-positive chronic myelogenous leukemia in complete cytogenetic response. J Clin Oncol 2009;27:3659-3663.
    • (2009) J Clin Oncol , vol.27 , pp. 3659-3663
    • Kantarjian, H.M.1    Shan, J.2    Jones, D.3
  • 29
    • 64149123286 scopus 로고    scopus 로고
    • Does a rise in the BCR-ABL1 transcript level identify chronic phase CML patients responding to imatinib who have a high risk of cytogenetic relapse?
    • Marin D, Khorashad JS, Foroni L, et al. Does a rise in the BCR-ABL1 transcript level identify chronic phase CML patients responding to imatinib who have a high risk of cytogenetic relapse? Br J Haematol 2009;145:373-375.
    • (2009) Br J Haematol , vol.145 , pp. 373-375
    • Marin, D.1    Khorashad, J.S.2    Foroni, L.3
  • 30
    • 70350509806 scopus 로고    scopus 로고
    • Determining the rise in BCR-ABL RNA that optimally predicts a kinase domain mutation in patients with chronic myeloid leukemia on imatinib
    • Press RD, Willis SG, Laudadio J, et al. Determining the rise in BCR-ABL RNA that optimally predicts a kinase domain mutation in patients with chronic myeloid leukemia on imatinib. Blood 2009;114:2598-2605.
    • (2009) Blood , vol.114 , pp. 2598-2605
    • Press, R.D.1    Willis, S.G.2    Laudadio, J.3
  • 31
    • 9144264829 scopus 로고    scopus 로고
    • Imatinib produces significantly superior molecular responses compared to interferon alfa plus cytarabine in patients with newly diagnosed chronic myeloid leukemia in chronic phase
    • Branford S, Rudzki Z, Harper A, et al. Imatinib produces significantly superior molecular responses compared to interferon alfa plus cytarabine in patients with newly diagnosed chronic myeloid leukemia in chronic phase. Leukemia 2003;17:2401-2409.
    • (2003) Leukemia , vol.17 , pp. 2401-2409
    • Branford, S.1    Rudzki, Z.2    Harper, A.3
  • 32
    • 67650587143 scopus 로고    scopus 로고
    • Delayed achievement of cytogenetic and molecular response is associated with increased risk of progression among patients with chronic myeloid leukemia in early chronic phase receiving high-dose or standard-dose imatinib therapy
    • Quintas-Cardama A, Kantarjian H, Jones D, et al. Delayed achievement of cytogenetic and molecular response is associated with increased risk of progression among patients with chronic myeloid leukemia in early chronic phase receiving high-dose or standard-dose imatinib therapy. Blood 2009;113:6315-6321.
    • (2009) Blood , vol.113 , pp. 6315-6321
    • Quintas-Cardama, A.1    Kantarjian, H.2    Jones, D.3
  • 33
    • 84862907694 scopus 로고    scopus 로고
    • Assessment of BCR-ABL1 transcript levels at 3 months is the only requirement for predicting outcome for patients with chronic myeloid leukemia treated with tyrosine kinase inhibitors
    • Marin D, Ibrahim AR, Lucas C, et al. Assessment of BCR-ABL1 transcript levels at 3 months is the only requirement for predicting outcome for patients with chronic myeloid leukemia treated with tyrosine kinase inhibitors. J Clin Oncol 2012;30:232-238.
    • (2012) J Clin Oncol , vol.30 , pp. 232-238
    • Marin, D.1    Ibrahim, A.R.2    Lucas, C.3
  • 34
    • 84865864744 scopus 로고    scopus 로고
    • Early molecular and cytogenetic response is predictive for long-term progression-free and overall survival in chronic myeloid leukemia (CML)
    • Hanfstein B, Muller MC, Hehlmann R, et al. Early molecular and cytogenetic response is predictive for long-term progression-free and overall survival in chronic myeloid leukemia (CML). Leukemia 2012;26:2096-2102.
    • (2012) Leukemia , vol.26 , pp. 2096-2102
    • Hanfstein, B.1    Muller, M.C.2    Hehlmann, R.3
  • 35
    • 84878263769 scopus 로고    scopus 로고
    • Combining BCR-ABL1 transcript levels at 3 and 6 months in chronic myeloid leukemia: Implications for early intervention strategies
    • Neelakantan P, Gerrard G, Lucas C, et al. Combining BCR-ABL1 transcript levels at 3 and 6 months in chronic myeloid leukemia: implications for early intervention strategies. Blood 2013;121:2739-2742.
    • (2013) Blood , vol.121 , pp. 2739-2742
    • Neelakantan, P.1    Gerrard, G.2    Lucas, C.3
  • 36
    • 84881478225 scopus 로고    scopus 로고
    • Early response (molecular and cytogenetic) and long-term outcomes in newly diagnosed chronic myeloid leukemia in chronic phase (CMLCP): Exploratory analysis of DASISION 3-year data
    • [abstract]. Abstract 1675
    • Saglio G, Kantarjian HM, Shah N, et al. Early response (molecular and cytogenetic) and long-term outcomes in newly diagnosed chronic myeloid leukemia in chronic phase (CMLCP): exploratory analysis of DASISION 3-year data [abstract]. Blood 2012;120:Abstract 1675.
    • (2012) Blood , vol.120
    • Saglio, G.1    Kantarjian, H.M.2    Shah, N.3
  • 37
    • 84891951795 scopus 로고    scopus 로고
    • Impact of early molecular response to nilotinib (NIL) or imatinib (IM) on the long-term outcomes of newly diagnosed patients (pts) with chronic myeloid leukemia in chronic phase (CML-CP): Landmark analysis of 4-year (y) data from ENESTnd
    • [abstract]. Abstract 7054
    • Saglio G, Hughes TP, Larson RA, et al. Impact of early molecular response to nilotinib (NIL) or imatinib (IM) on the long-term outcomes of newly diagnosed patients (pts) with chronic myeloid leukemia in chronic phase (CML-CP): landmark analysis of 4-year (y) data from ENESTnd [abstract]. J Clin Oncol 2013;31(Suppl):Abstract 7054.
    • (2013) J Clin Oncol , vol.31 , Issue.SUPPL.
    • Saglio, G.1    Hughes, T.P.2    Larson, R.A.3
  • 38
    • 77953725855 scopus 로고    scopus 로고
    • Dasatinib versus imatinib in newly diagnosed chronic-phase chronic myeloid leukemia
    • Kantarjian H, Shah NP, Hochhaus A, et al. Dasatinib versus imatinib in newly diagnosed chronic-phase chronic myeloid leukemia. N Engl J Med 2010;362:2260-2270.
    • (2010) N Engl J Med , vol.362 , pp. 2260-2270
    • Kantarjian, H.1    Shah, N.P.2    Hochhaus, A.3
  • 39
    • 77953691179 scopus 로고    scopus 로고
    • Nilotinib versus imatinib for newly diagnosed chronic myeloid leukemia
    • Saglio G, Kim DW, Issaragrisil S, et al. Nilotinib versus imatinib for newly diagnosed chronic myeloid leukemia. N Engl J Med 2010;362:2251-2259.
    • (2010) N Engl J Med , vol.362 , pp. 2251-2259
    • Saglio, G.1    Kim, D.W.2    Issaragrisil, S.3
  • 40
    • 84881289808 scopus 로고    scopus 로고
    • Early responses predict better outcomes in patients with newly diagnosed chronic myeloid leukemia: Results with four tyrosine kinase inhibitor modalities
    • Jain P, Kantarjian H, Nazha A, et al. Early responses predict better outcomes in patients with newly diagnosed chronic myeloid leukemia: results with four tyrosine kinase inhibitor modalities. Blood 2013;121:4867-4874.
    • (2013) Blood , vol.121 , pp. 4867-4874
    • Jain, P.1    Kantarjian, H.2    Nazha, A.3
  • 41
    • 84857510443 scopus 로고    scopus 로고
    • Responses to second-line tyrosine kinase inhibitors are durable: An intention-to-treat analysis in chronic myeloid leukemia patients
    • Milojkovic D, Apperley JF, Gerrard G, et al. Responses to second-line tyrosine kinase inhibitors are durable: an intention-to-treat analysis in chronic myeloid leukemia patients. Blood 2012;119:1838-1843.
    • (2012) Blood , vol.119 , pp. 1838-1843
    • Milojkovic, D.1    Apperley, J.F.2    Gerrard, G.3
  • 42
    • 84870752970 scopus 로고    scopus 로고
    • Initial molecular response at 3 months may predict both response and event-free survival at 24 months in imatinib-resistant or -intolerant patients with Philadelphia chromosome-positive chronic myeloid leukemia in chronic phase treated with nilotinib
    • Branford S, Kim DW, Soverini S, et al. Initial molecular response at 3 months may predict both response and event-free survival at 24 months in imatinib-resistant or -intolerant patients with Philadelphia chromosome-positive chronic myeloid leukemia in chronic phase treated with nilotinib. J Clin Oncol 2012;30:4323-4329.
    • (2012) J Clin Oncol , vol.30 , pp. 4323-4329
    • Branford, S.1    Kim, D.W.2    Soverini, S.3
  • 43
    • 84874000814 scopus 로고    scopus 로고
    • BCR-ABL1 transcript at 3 months predicts long-term outcomes following second generation tyrosine kinase inhibitor therapy in the patients with chronic myeloid leukaemia in chronic phase who failed Imatinib
    • Kim DD, Lee H, Kamel-Reid S, Lipton JH. BCR-ABL1 transcript at 3 months predicts long-term outcomes following second generation tyrosine kinase inhibitor therapy in the patients with chronic myeloid leukaemia in chronic phase who failed Imatinib. Br J Haematol 2013;160:630-639.
    • (2013) Br J Haematol , vol.160 , pp. 630-639
    • Kim, D.D.1    Lee, H.2    Kamel-Reid, S.3    Lipton, J.H.4
  • 44
    • 84875882565 scopus 로고    scopus 로고
    • Early switch to nilotinib does not overcome the adverse outcome for cml patients failing to achieve early molecular response on imatinib, despite excellent overall outcomes in the TIDEL II trial
    • [abstract]. Abstract 3771
    • Yeung DT, Osborn MP, White DL, et al. Early switch to nilotinib does not overcome the adverse outcome for cml patients failing to achieve early molecular response on imatinib, despite excellent overall outcomes in the TIDEL II trial [abstract]. Blood 2012;120:Abstract 3771.
    • (2012) Blood , vol.120
    • Yeung, D.T.1    Osborn, M.P.2    White, D.L.3
  • 45
    • 84860346274 scopus 로고    scopus 로고
    • Pulmonary arterial hypertension in patients treated by dasatinib
    • Montani D, Bergot E, Gunther S, et al. Pulmonary arterial hypertension in patients treated by dasatinib. Circulation 2012;125:2128-2137.
    • (2012) Circulation , vol.125 , pp. 2128-2137
    • Montani, D.1    Bergot, E.2    Gunther, S.3
  • 46
    • 84878899268 scopus 로고    scopus 로고
    • Rates of peripheral arterial occlusive disease in patients with chronic myeloid leukemia in the chronic phase treated with imatinib, nilotinib, or nontyrosine kinase therapy: A retrospective cohort analysis
    • Giles FJ, Mauro MJ, Hong F, et al. Rates of peripheral arterial occlusive disease in patients with chronic myeloid leukemia in the chronic phase treated with imatinib, nilotinib, or nontyrosine kinase therapy: a retrospective cohort analysis. Leukemia 2013;27:1310-1315.
    • (2013) Leukemia , vol.27 , pp. 1310-1315
    • Giles, F.J.1    Mauro, M.J.2    Hong, F.3
  • 47
    • 84891953577 scopus 로고    scopus 로고
    • Analysis of the cardiovascular risk profile of Ph+ leukemia patients treated with ponatinib
    • [abstract]. Abstract 7048
    • Khoury HJ, Cortes JE, Kim DW, et al. Analysis of the cardiovascular risk profile of Ph+ leukemia patients treated with ponatinib [abstract]. J Clin Oncol 2013;31(Suppl):Abstract 7048.
    • (2013) J Clin Oncol , vol.31 , Issue.SUPPL.
    • Khoury, H.J.1    Cortes, J.E.2    Kim, D.W.3
  • 48
    • 84885947027 scopus 로고    scopus 로고
    • Disease patterns for patients (pts) with chronic myeloid leukemia (CML) that have BCR-ABL transcript levels > 10% at 3 month of therapy with tyrosine kinase inhibitors (TKIs)
    • [abstract]. Abstract 3757
    • Nazha A, Kantarjian HM, Jain P, et al. Disease patterns for patients (pts) with chronic myeloid leukemia (CML) that have BCR-ABL transcript levels > 10% at 3 month of therapy with tyrosine kinase inhibitors (TKIs) [abstract]. Blood 2012;120:Abstract 3757.
    • (2012) Blood , vol.120
    • Nazha, A.1    Kantarjian, H.M.2    Jain, P.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.