Cardiomyocyte Ogt limits ventricular dysfunction in mice following pressure overload without affecting hypertrophy

Basic Research in Cardiology

Volumn 112, Issue 3, 2017, Pages

  Dassanayaka, Sujith ^a   Brainard, Robert E ^a   Watson, Lewis J ^a,b   Long, Bethany W ^a   Brittian, Kenneth R ^a   DeMartino, Angelica M ^a   Aird, Allison L ^a   Gumpert, Anna M ^a   Audam, Timothy N ^a   Kilfoil, Peter J ^a   Muthusamy, Senthilkumar ^a   Hamid, Tariq ^a,c   Prabhu, Sumanth D ^a,c   Jones, Steven P ^a  

^a University of Louisville School of Medicine   (United States)

^b Pikeville College School of Osteopathic Medicine   (United States)

^c University of Alabama at Birmingham   (United States)

Author keywords

Glycosylation; Heart failure; Hexosamine biosynthetic pathway; Metabolism

Indexed keywords

ALPHA SMOOTH MUSCLE ACTIN; HOMEOBOX PROTEIN NKX-2.5; MESSENGER RNA; N ACETYLGLUCOSAMINYLTRANSFERASE; PROTEIN BCL 2; TRANSCRIPTION FACTOR GATA 4; VASCULOTROPIN A; O-GLCNAC TRANSFERASE;

ACYLATION; ADULT; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; AORTA CONSTRICTION; ARTICLE; CARDIAC MUSCLE; CARDIAC MUSCLE CELL; CELL DEDIFFERENTIATION; CONTROLLED STUDY; DISEASE EXACERBATION; GENE DELETION; HEART FAILURE; HEART LEFT VENTRICLE FAILURE; HEART LEFT VENTRICLE HYPERTROPHY; HEART LEFT VENTRICLE OVERLOAD; HEART MUSCLE FIBROSIS; HUMAN; HUMAN CELL; HUMAN TISSUE; MALE; MIDDLE AGED; MOUSE; NONHUMAN; PHENOTYPIC VARIATION; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION; WILD TYPE; ANIMAL; APOPTOSIS; CARDIOMEGALY; DISEASE MODEL; IMMUNOBLOTTING; KNOCKOUT MOUSE; METABOLISM; POLYMERASE CHAIN REACTION; TUNEL ASSAY;

ANIMALS; APOPTOSIS; CARDIOMEGALY; DISEASE MODELS, ANIMAL; HEART FAILURE; HUMANS; IMMUNOBLOTTING; IN SITU NICK-END LABELING; MALE; MICE; MICE, KNOCKOUT; MIDDLE AGED; MYOCYTES, CARDIAC; N-ACETYLGLUCOSAMINYLTRANSFERASES; POLYMERASE CHAIN REACTION;

EID: 85015624771     PISSN: 03008428     EISSN: 14351803     Source Type: Journal    
DOI: 10.1007/s00395-017-0612-7     Document Type: Article

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