T cells specific for post-translational modifications escape intrathymic tolerance induction

Nature Communications

Volumn 9, Issue 1, 2018, Pages

  Raposo, Bruno ^a,f   Merky, Patrick ^a   Lundqvist, Christina ^c   Yamada, Hisakata ^b   Urbonaviciute, Vilma ^a   Niaudet, Colin ^a   Viljanen, Johan ^d   Kihlberg, Jan ^d   Kyewski, Bruno ^e   Ekwall, Olov ^c   Holmdahl, Rikard ^a   Bäcklund, Johan ^a  

^a KAROLINSKA INSTITUTE   (Sweden)

^b KYUSHU UNIVERSITY   (Japan)

^c UNIVERSITY OF GOTHENBURG   (Sweden)

^d UPPSALA UNIVERSITY   (Sweden)

^e GERMAN CANCER RESEARCH CENTER DKFZ   (Germany)

^f HARVARD MEDICAL SCHOOL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

COMPLEMENTARY DNA; GLUTAMATE DECARBOXYLASE 67; INSULIN; T LYMPHOCYTE RECEPTOR; AUTOANTIGEN; COLLAGEN TYPE 2;

ANTIGEN; CELL; COLLAGEN; GENE EXPRESSION; IMMUNITY; INDUCED RESPONSE; PROTEIN; TOLERANCE;

ADOPTIVE TRANSFER; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIGEN RECOGNITION; ARTICLE; AUTOIMMUNITY; CELL LINEAGE; CELL SPECIFICITY; COLLAGEN-INDUCED ARTHRITIS; CONTROLLED STUDY; DENDRITIC CELL; DISEASE COURSE; ENZYME LINKED IMMUNOSPOT ASSAY; FEMALE; FLOW CYTOMETRY; HUMAN; HUMAN CELL; IMMUNOLOGICAL TOLERANCE; MOUSE; NONHUMAN; PROTEIN PROCESSING; REGULATORY T LYMPHOCYTE; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; T LYMPHOCYTE; THYMOCYTE; THYMUS TRANSPLANTATION; UPREGULATION; ANIMAL; DISEASE MODEL; EXPERIMENTAL ARTHRITIS; IMMUNOLOGY; THYMUS; TRANSGENIC MOUSE;

ANIMALS; ARTHRITIS, EXPERIMENTAL; AUTOANTIGENS; AUTOIMMUNITY; CENTRAL TOLERANCE; COLLAGEN TYPE II; DISEASE MODELS, ANIMAL; MICE; MICE, TRANSGENIC; PROTEIN PROCESSING, POST-TRANSLATIONAL; T-LYMPHOCYTES; THYMOCYTES; THYMUS GLAND;

EID: 85041024537     PISSN: None     EISSN: 20411723     Source Type: Journal    
DOI: 10.1038/s41467-017-02763-y     Document Type: Article

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