CD4+ T cell anergy prevents autoimmunity and generates regulatory T cell precursors

Nature Immunology

Volumn 17, Issue 3, 2016, Pages 304-314

  Kalekar, Lokesh A ^a   Schmiel, Shirdi E ^a   Nandiwada, Sarada L ^a   Lam, Wing Y ^a   Barsness, Laura O ^a   Zhang, Na ^a   Stritesky, Gretta L ^a   Malhotra, Deepali ^a   Pauken, Kristen E ^a   Linehan, Jonathan L ^a   O'Sullivan, M Gerard ^b   Fife, Brian T ^a   Hogquist, Kristin A ^a   Jenkins, Marc K ^a   Mueller, Daniel L ^a  

^a UNIVERSITY OF MINNESOTA MEDICAL SCHOOL   (United States)

^b UNIVERSITY OF MINNESOTA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

5' NUCLEOTIDASE; FETAL ANTIGEN; GAMMA INTERFERON; HERMES ANTIGEN; INTERLEUKIN 10; INTERLEUKIN 17; INTERLEUKIN 2; INTERLEUKIN 21; NEUROPILIN 1; PROTEIN; PROTEIN FR4; PROTEIN NRP1; T LYMPHOCYTE RECEPTOR; TRANSCRIPTION FACTOR FOXP3; TUMOR NECROSIS FACTOR; UNCLASSIFIED DRUG; CYTOKINE; FORKHEAD TRANSCRIPTION FACTOR; FOXP3 PROTEIN, MOUSE; LYMPHOCYTE ANTIGEN RECEPTOR;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIGEN RECOGNITION; ARTHRITIS; ARTICLE; AUTOIMMUNITY; CD4+ T LYMPHOCYTE; CLONAL ANERGY; CONTROLLED STUDY; DNA METHYLATION; FEMALE; IMMUNOPATHOLOGY; INFLAMMATORY BOWEL DISEASE; LYMPHOCYTE DIFFERENTIATION; LYMPHOCYTOPENIA; MOUSE; NONHUMAN; PRE T LYMPHOCYTE; PREGNANCY; PRIORITY JOURNAL; PROTEIN EXPRESSION; REGULATORY T LYMPHOCYTE; T LYMPHOCYTE SUBPOPULATION; ADOPTIVE TRANSFER; ANIMAL; CELL DIFFERENTIATION; CELL PROLIFERATION; ENZYME LINKED IMMUNOSORBENT ASSAY; EXPERIMENTAL ARTHRITIS; FLOW CYTOMETRY; HISTOCOMPATIBILITY; IMMUNOBLOTTING; IMMUNOLOGICAL TOLERANCE; IMMUNOLOGY; KNOCKOUT MOUSE; MALE; METABOLISM; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; T LYMPHOCYTE RECEPTOR GENE; THYMOCYTE;

ADOPTIVE TRANSFER; ANIMALS; ARTHRITIS, EXPERIMENTAL; AUTOIMMUNITY; CD4-POSITIVE T-LYMPHOCYTES; CELL DIFFERENTIATION; CELL PROLIFERATION; CLONAL ANERGY; CYTOKINES; ENZYME-LINKED IMMUNOSORBENT ASSAY; FEMALE; FLOW CYTOMETRY; FORKHEAD TRANSCRIPTION FACTORS; GENES, T-CELL RECEPTOR ALPHA; HISTOCOMPATIBILITY, MATERNAL-FETAL; IMMUNOBLOTTING; MALE; MICE; MICE, KNOCKOUT; NEUROPILIN-1; PERIPHERAL TOLERANCE; PRECURSOR CELLS, T-LYMPHOID; PREGNANCY; RECEPTORS, ANTIGEN, T-CELL; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; SELF TOLERANCE; T-LYMPHOCYTES, REGULATORY; THYMOCYTES;

EID: 84962233292     PISSN: 15292908     EISSN: 15292916     Source Type: Journal    
DOI: 10.1038/ni.3331     Document Type: Article

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