Ontogeny of the B- and T-cell response in a primary Zika virus infection of a dengue-naïve individual during the 2016 outbreak in Miami, FL

PLoS Neglected Tropical Diseases

Volumn 11, Issue 12, 2017, Pages

  Ricciardi, Michael J ^a   Magnani, Diogo M ^a   Grifoni, Alba ^b   Kwon, Young Chan ^c   Gutman, Martin J ^a   Grubaugh, Nathan D ^d   Gangavarapu, Karthik ^d   Sharkey, Mark ^a   Silveira, Cassia G T ^e   Bailey, Varian K ^a   Pedreño Lopez, Núria ^a   Gonzalez Nieto, Lucas ^a   Maxwell, Helen S ^a   Domingues, Aline ^a   Martins, Mauricio A ^a   Pham, John ^b   Weiskopf, Daniela ^b   Altman, John ^f   Kallas, Esper G ^e   Andersen, Kristian G ^d   Stevenson, Mario ^a   Lichtenberger, Paola ^a   Choe, Hyeryun ^c   Whitehead, Stephen S ^g   Sette, Alessandro ^b   Watkins, David I ^a   more..

^a UNIVERSITY OF MIAMI MILLER SCHOOL OF MEDICINE   (United States)

^b LA JOLLA INSTITUTE FOR ALLERGY AND IMMUNOLOGY   (United States)

^c SCRIPPS RESEARCH INSTITUTE   (United States)

^d SCRIPPS RESEARCH INSTITUTE   (United States)

^e UNIVERSITY OF SÃO PAULO   (Brazil)

^f EMORY UNIVERSITY SCHOOL OF MEDICINE   (United States)

^g NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

GAMMA INTERFERON; GRANZYME B; IMMUNOGLOBULIN G; IMMUNOGLOBULIN M; NONSTRUCTURAL PROTEIN 1; PROGRAMMED DEATH 1 RECEPTOR; VIRUS RNA; VIRUS ANTIBODY; VIRUS ENVELOPE PROTEIN;

ADULT; ALLELE; ANTIBODY DEPENDENT ENHANCEMENT; ANTIBODY RESPONSE; ARTICLE; B LYMPHOCYTE; BLOOD SAMPLING; CASE REPORT; CD4+ T LYMPHOCYTE; CD8+ T LYMPHOCYTE; CLINICAL ARTICLE; CONTROLLED STUDY; CROSS REACTION; DENGUE; DENGUE VIRUS 1; DENGUE VIRUS 2; DENGUE VIRUS 3; DENGUE VIRUS 4; ENZYME LINKED IMMUNOSORBENT ASSAY; ENZYME LINKED IMMUNOSPOT ASSAY; FEMALE; FLORIDA; FLOW CYTOMETRY; HUMAN; IMMUNE RESPONSE; K-562 CELL LINE; LYMPHOCYTE; MACULOPAPULAR RASH; MALAISE; NUCLEOTIDE SEQUENCE; ONTOGENY; PERIPHERAL BLOOD MONONUCLEAR CELL; PHENOTYPE; PHYLOGENETIC TREE; PLASMABLAST; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SEROTYPE; STAINING; T LYMPHOCYTE; ZIKA FEVER; ZIKA VIRUS; BLOOD; DENGUE VIRUS; EPIDEMIC; GENETICS; IMMUNOLOGY; RASH; VIROLOGY;

ADULT; ANTIBODIES, VIRAL; CD4-POSITIVE T-LYMPHOCYTES; CD8-POSITIVE T-LYMPHOCYTES; CROSS REACTIONS; DENGUE VIRUS; DISEASE OUTBREAKS; EXANTHEMA; FEMALE; FLORIDA; HUMANS; IMMUNOGLOBULIN G; IMMUNOGLOBULIN M; RNA, VIRAL; VIRAL ENVELOPE PROTEINS; ZIKA VIRUS; ZIKA VIRUS INFECTION;

EID: 85040020422     PISSN: 19352727     EISSN: 19352735     Source Type: Journal    
DOI: 10.1371/journal.pntd.0006000     Document Type: Article

References (82)

1. Sikka V, Chattu VK, Popli RK, Galwankar SC, Kelkar D, Sawicki SG, et al. The Emergence of Zika Virus as a Global Health Security Threat: A Review and a Consensus Statement of the INDUSEM Joint working Group (JWG). J Glob Infect Dis. 2016;8(1):3–15. doi: 10.4103/0974-777X.176140 27013839; PubMed Central PMCID: PMCPMC4785754.
2. Camacho E, Paternina-Gomez M, Blanco PJ, Osorio JE, Aliota MT, Detection of Autochthonous Zika Virus Transmission in Sincelejo, Colombia. Emerg Infect Dis. 2016;22(5):927–9. doi: 10.3201/eid2205.160023 27089253; PubMed Central PMCID: PMCPMC4861534.
3. Duffy MR, Chen TH, Hancock WT, Powers AM, Kool JL, Lanciotti RS, et al. Zika virus outbreak on Yap Island, Federated States of Micronesia. N Engl J Med. 2009;360(24):2536–43. doi: 10.1056/NEJMoa0805715 19516034.
4. Hayes EB, Zika virus outside Africa. Emerg Infect Dis. 2009;15(9):1347–50. doi: 10.3201/eid1509.090442 19788800; PubMed Central PMCID: PMCPMC2819875.
5. Zanluca C, Melo VC, Mosimann AL, Santos GI, Santos CN, Luz K, First report of autochthonous transmission of Zika virus in Brazil. Mem Inst Oswaldo Cruz. 2015;110(4):569–72. doi: 10.1590/0074-02760150192 26061233; PubMed Central PMCID: PMCPMC4501423.
6. Fields BN, Knipe DM, Fields virology. 2nd ed. New York: Raven Press; 1990.
7. Dick GW, Kitchen SF, Haddow AJ, Zika virus. I. Isolations and serological specificity. Trans R Soc Trop Med Hyg. 1952;46(5):509–20. 12995440.
8. Vasilakis N, Weaver SC, Flavivirus transmission focusing on Zika. Curr Opin Virol. 2017;22:30–5. doi: 10.1016/j.coviro.2016.11.007 27936448; PubMed Central PMCID: PMCPMC5346038.
9. McCrae AW, Kirya BG, Yellow fever and Zika virus epizootics and enzootics in Uganda. Trans R Soc Trop Med Hyg. 1982;76(4):552–62. 6304948.
10. Musso D, Nilles EJ, Cao-Lormeau VM, Rapid spread of emerging Zika virus in the Pacific area. Clin Microbiol Infect. 2014;20(10):O595–6. doi: 10.1111/1469-0691.12707 24909208.
11. Kraemer MU, Sinka ME, Duda KA, Mylne AQ, Shearer FM, Barker CM, et al. The global distribution of the arbovirus vectors Aedes aegypti and Ae. albopictus. Elife. 2015;4:e08347. doi: 10.7554/eLife.08347 26126267; PubMed Central PMCID: PMCPMC4493616.
12. Calisher CH, Karabatsos N, Dalrymple JM, Shope RE, Porterfield JS, Westaway EG, et al. Antigenic relationships between flaviviruses as determined by cross-neutralization tests with polyclonal antisera. J Gen Virol. 1989;70 (Pt 1):37–43. doi: 10.1099/0022-1317-70-1-37 2543738.
13. Mansfield KL, Horton DL, Johnson N, Li L, Barrett AD, Smith DJ, et al. Flavivirus-induced antibody cross-reactivity. J Gen Virol. 2011;92(Pt 12):2821–9. doi: 10.1099/vir.0.031641-0 21900425; PubMed Central PMCID: PMCPMC3352572.
14. Beltramello M, Williams KL, Simmons CP, Macagno A, Simonelli L, Quyen NT, et al. The human immune response to Dengue virus is dominated by highly cross-reactive antibodies endowed with neutralizing and enhancing activity. Cell Host Microbe. 2010;8(3):271–83. Epub 2010/09/14. doi: 10.1016/j.chom.2010.08.007 20833378; PubMed Central PMCID: PMCPMC3884547.
15. Dejnirattisai W, Jumnainsong A, Onsirisakul N, Fitton P, Vasanawathana S, Limpitikul W, et al. Cross-reacting antibodies enhance dengue virus infection in humans. Science. 2010;328(5979):745–8. Epub 2010/05/08. doi: 10.1126/science.1185181 20448183; PubMed Central PMCID: PMCPMC3837288.
16. de Alwis R, Beltramello M, Messer WB, Sukupolvi-Petty S, Wahala WM, Kraus A, et al. In-depth analysis of the antibody response of individuals exposed to primary dengue virus infection. PLoS Negl Trop Dis. 2011;5(6):e1188. Epub 2011/06/30. doi: 10.1371/journal.pntd.0001188 21713020; PubMed Central PMCID: PMCPMC3119640.
17. Stettler K, Beltramello M, Espinosa DA, Graham V, Cassotta A, Bianchi S, et al. Specificity, cross-reactivity, and function of antibodies elicited by Zika virus infection. Science. 2016;353(6301):823–6. doi: 10.1126/science.aaf8505 27417494.
18. Keasey SL, Pugh CL, Jensen SM, Smith JL, Hontz RD, Durbin AP, et al. Antibody responses to Zika virus infections in flavivirus-endemic environments. Clin Vaccine Immunol. 2017. doi: 10.1128/CVI.00036-17 28228395.
19. Florida investigation links four recent Zika cases to local mosquito-borne virus transmission. The Centers for Disease Control and Prevention. 2016 [cited 11 March 2017]. Available at: https://www.cdc.gov/media/releases/2016/p0729-florida-zika-cases.html
20. Likos A, Griffin I, Bingham AM, Stanek D, Fischer M, White S, et al. Local Mosquito-Borne Transmission of Zika Virus—Miami-Dade and Broward Counties, Florida, June-August 2016. MMWR Morb Mortal Wkly Rep. 2016;65(38):1032–8. doi: 10.15585/mmwr.mm6538e1 27684886.
21. Grubaugh ND, Ladner JT, Kraemer MUG, Dudas G, Tan AL, Gangavarapu K, et al. Genomic epidemiology reveals multiple introductions of Zika virus into the United States. Nature. 2017;546(7658):401–5. Epub 2017/05/26. doi: 10.1038/nature22400 28538723; PubMed Central PMCID: PMCPMC5536180.
22. Monaghan AJ, Morin CW, Steinhoff DF, Wilhelmi O, Hayden M, Quattrochi DA, et al. On the Seasonal Occurrence and Abundance of the Zika Virus Vector Mosquito Aedes Aegypti in the Contiguous United States. PLoS Curr. 2016;8. doi: 10.1371/currents.outbreaks.50dfc7f46798675fc63e7d7da563da76 27066299; PubMed Central PMCID: PMCPMC4807952.
23. Morlan HB, Tinker ME, Distribution of Aedes aegypti infestations in the United States. Am J Trop Med Hyg. 1965;14(6):892–9. 5840643.
24. Simpson DI, Zika Virus Infection in Man. Trans R Soc Trop Med Hyg. 1964;58:335–8. 14175744.
25. Lazear HM, Diamond MS, Zika Virus: New Clinical Syndromes and Its Emergence in the Western Hemisphere. J Virol. 2016;90(10):4864–75. doi: 10.1128/JVI.00252-16 26962217; PubMed Central PMCID: PMCPMC4859708.
26. Mlakar J, Korva M, Tul N, Popovic M, Poljsak-Prijatelj M, Mraz J, et al. Zika Virus Associated with Microcephaly. N Engl J Med. 2016;374(10):951–8. doi: 10.1056/NEJMoa1600651 26862926.
27. Brasil P, Pereira JP, Jr.Moreira ME, Ribeiro Nogueira RM, Damasceno L, Wakimoto M, et al. Zika Virus Infection in Pregnant Women in Rio de Janeiro. N Engl J Med. 2016;375(24):2321–34. doi: 10.1056/NEJMoa1602412 26943629; PubMed Central PMCID: PMCPMC5323261.
28. Sarno M, Sacramento GA, Khouri R, do Rosario MS, Costa F, Archanjo G, et al. Zika Virus Infection and Stillbirths: A Case of Hydrops Fetalis, Hydranencephaly and Fetal Demise. PLoS Negl Trop Dis. 2016;10(2):e0004517. doi: 10.1371/journal.pntd.0004517 26914330; PubMed Central PMCID: PMCPMC4767410.
29. van der Eijk AA, van Genderen PJ, Verdijk RM, Reusken CB, Mogling R, van Kampen JJ, et al. Miscarriage Associated with Zika Virus Infection. N Engl J Med. 2016;375(10):1002–4. doi: 10.1056/NEJMc1605898 27463941.
30. Parra B, Lizarazo J, Jimenez-Arango JA, Zea-Vera AF, Gonzalez-Manrique G, Vargas J, et al. Guillain-Barre Syndrome Associated with Zika Virus Infection in Colombia. N Engl J Med. 2016;375(16):1513–23. doi: 10.1056/NEJMoa1605564 27705091.
31. Brasil P, Sequeira PC, Freitas AD, Zogbi HE, Calvet GA, de Souza RV, et al. Guillain-Barre syndrome associated with Zika virus infection. Lancet. 2016;387(10026):1482. doi: 10.1016/S0140-6736(16)30058-7 27115821.
32. Cao-Lormeau VM, Blake A, Mons S, Lastere S, Roche C, Vanhomwegen J, et al. Guillain-Barre Syndrome outbreak associated with Zika virus infection in French Polynesia: a case-control study. Lancet. 2016;387(10027):1531–9. doi: 10.1016/S0140-6736(16)00562-6 26948433.
33. Quick J, Grubaugh ND, Pullan ST, Claro IM, Smith AD, Gangavarapu K, et al. Multiplex PCR method for MinION and Illumina sequencing of Zika and other virus genomes directly from clinical samples. Nat Protoc. 2017;12(6):1261–76. Epub 2017/05/26. doi: 10.1038/nprot.2017.066 28538739.
34. Bolger AM, Lohse M, Usadel B, Trimmomatic: a flexible trimmer for Illumina sequence data. Bioinformatics. 2014;30(15):2114–20. doi: 10.1093/bioinformatics/btu170 24695404; PubMed Central PMCID: PMCPMC4103590.
35. Li H, Handsaker B, Wysoker A, Fennell T, Ruan J, Homer N, et al. The Sequence Alignment/Map format and SAMtools. Bioinformatics. 2009;25(16):2078–9. doi: 10.1093/bioinformatics/btp352 19505943; PubMed Central PMCID: PMCPMC2723002.
36. Kearse M, Moir R, Wilson A, Stones-Havas S, Cheung M, Sturrock S, et al. Geneious Basic: an integrated and extendable desktop software platform for the organization and analysis of sequence data. Bioinformatics. 2012;28(12):1647–9. doi: 10.1093/bioinformatics/bts199 22543367; PubMed Central PMCID: PMCPMC3371832.
37. Metsky HC, Matranga CB, Wohl S, Schaffner SF, Freije CA, Winnicki SM, et al. Zika virus evolution and spread in the Americas. Nature. 2017;546(7658):411–5. Epub 2017/05/26. doi: 10.1038/nature22402 28538734.
38. Katoh K, Standley DM, MAFFT multiple sequence alignment software version 7: improvements in performance and usability. Mol Biol Evol. 2013;30(4):772–80. doi: 10.1093/molbev/mst010 23329690; PubMed Central PMCID: PMCPMC3603318.
39. Yang Z, Maximum likelihood phylogenetic estimation from DNA sequences with variable rates over sites: approximate methods. J Mol Evol. 1994;39(3):306–14. 7932792.
40. Guindon S, Gascuel O, A simple, fast, and accurate algorithm to estimate large phylogenies by maximum likelihood. Syst Biol. 2003;52(5):696–704. 14530136.
41. Huerta-Cepas J, Serra F, Bork P, ETE 3: Reconstruction, Analysis, and Visualization of Phylogenomic Data. Mol Biol Evol. 2016;33(6):1635–8. doi: 10.1093/molbev/msw046 26921390; PubMed Central PMCID: PMCPMC4868116.
42. Kraus AA, Messer W, Haymore LB, de Silva AM, Comparison of plaque- and flow cytometry-based methods for measuring dengue virus neutralization. J Clin Microbiol. 2007;45(11):3777–80. doi: 10.1128/JCM.00827-07 17804661; PubMed Central PMCID: PMCPMC2168473.
43. de Alwis R, de Silva AM, Measuring antibody neutralization of dengue virus (DENV) using a flow cytometry-based technique. Methods Mol Biol. 2014;1138:27–39. doi: 10.1007/978-1-4939-0348-1_3 24696329.
44. Durbin AP, Karron RA, Sun W, Vaughn DW, Reynolds MJ, Perreault JR, et al. Attenuation and immunogenicity in humans of a live dengue virus type-4 vaccine candidate with a 30 nucleotide deletion in its 3'-untranslated region. Am J Trop Med Hyg. 2001;65(5):405–13. 11716091.
45. Richard AS, Shim BS, Kwon YC, Zhang R, Otsuka Y, Schmitt K, et al. AXL-dependent infection of human fetal endothelial cells distinguishes Zika virus from other pathogenic flaviviruses. Proc Natl Acad Sci U S A. 2017;114(8):2024–9. doi: 10.1073/pnas.1620558114 28167751; PubMed Central PMCID: PMCPMC5338370.
46. Carrasco Pro S, Sidney J, Paul S, Lindestam Arlehamn C, Weiskopf D, Peters B, et al. Automatic Generation of Validated Specific Epitope Sets. J Immunol Res. 2015;2015:763461. doi: 10.1155/2015/763461 26568965; PubMed Central PMCID: PMCPMC4629045.
47. Weiskopf D, Angelo MA, de Azeredo EL, Sidney J, Greenbaum JA, Fernando AN, et al. Comprehensive analysis of dengue virus-specific responses supports an HLA-linked protective role for CD8+ T cells. Proc Natl Acad Sci U S A. 2013;110(22):E2046–53. doi: 10.1073/pnas.1305227110 23580623; PubMed Central PMCID: PMCPMC3670335.
48. Weiskopf D, Bangs DJ, Sidney J, Kolla RV, De Silva AD, de Silva AM, et al. Dengue virus infection elicits highly polarized CX3CR1+ cytotoxic CD4+ T cells associated with protective immunity. Proc Natl Acad Sci U S A. 2015;112(31):E4256–63. doi: 10.1073/pnas.1505956112 26195744; PubMed Central PMCID: PMCPMC4534238.
49. Wrammert J, Onlamoon N, Akondy RS, Perng GC, Polsrila K, Chandele A, et al. Rapid and massive virus-specific plasmablast responses during acute dengue virus infection in humans. J Virol. 2012;86(6):2911–8. doi: 10.1128/JVI.06075-11 22238318; PubMed Central PMCID: PMCPMC3302324.
50. Xu M, Hadinoto V, Appanna R, Joensson K, Toh YX, Balakrishnan T, et al. Plasmablasts generated during repeated dengue infection are virus glycoprotein-specific and bind to multiple virus serotypes. J Immunol. 2012;189(12):5877–85. doi: 10.4049/jimmunol.1201688 23152560.
51. Dowd KA, Pierson TC, Antibody-mediated neutralization of flaviviruses: a reductionist view. Virology. 2011;411(2):306–15. doi: 10.1016/j.virol.2010.12.020 21255816; PubMed Central PMCID: PMCPMC3100196.
52. Nybakken GE, Oliphant T, Johnson S, Burke S, Diamond MS, Fremont DH, Structural basis of West Nile virus neutralization by a therapeutic antibody. Nature. 2005;437(7059):764–9. doi: 10.1038/nature03956 16193056.
53. Dejnirattisai W, Supasa P, Wongwiwat W, Rouvinski A, Barba-Spaeth G, Duangchinda T, et al. Dengue virus sero-cross-reactivity drives antibody-dependent enhancement of infection with zika virus. Nat Immunol. 2016;17(9):1102–8. doi: 10.1038/ni.3515 27339099; PubMed Central PMCID: PMCPMC4994874.
54. Priyamvada L, Cho A, Onlamoon N, Zheng NY, Huang M, Kovalenkov Y, et al. B Cell Responses during Secondary Dengue Virus Infection Are Dominated by Highly Cross-Reactive, Memory-Derived Plasmablasts. J Virol. 2016;90(12):5574–85. doi: 10.1128/JVI.03203-15 27030262; PubMed Central PMCID: PMCPMC4886779.
55. Priyamvada L, Quicke KM, Hudson WH, Onlamoon N, Sewatanon J, Edupuganti S, et al. Human antibody responses after dengue virus infection are highly cross-reactive to Zika virus. Proc Natl Acad Sci U S A. 2016;113(28):7852–7. doi: 10.1073/pnas.1607931113 27354515; PubMed Central PMCID: PMCPMC4948328.
56. Case Counts in the US. The Centers for Disease Control and Prevention. 2016 [cited 11 March 2017]. Available at: https://www.cdc.gov/zika/geo/united-states.html
57. Osuna CE, Lim SY, Deleage C, Griffin BD, Stein D, Schroeder LT, et al. Zika viral dynamics and shedding in rhesus and cynomolgus macaques. Nat Med. 2016;22(12):1448–55. doi: 10.1038/nm.4206 27694931; PubMed Central PMCID: PMCPMC5293594.
58. Coffey LL, Pesavento PA, Keesler RI, Singapuri A, Watanabe J, Watanabe R, et al. Zika Virus Tissue and Blood Compartmentalization in Acute Infection of Rhesus Macaques. PLoS One. 2017;12(1):e0171148. doi: 10.1371/journal.pone.0171148 28141843; PubMed Central PMCID: PMCPMC5283740 employees does not alter our adherence to PLOS ONE policies on sharing data and materials.
59. Dudley DM, Aliota MT, Mohr EL, Weiler AM, Lehrer-Brey G, Weisgrau KL, et al. A rhesus macaque model of Asian-lineage Zika virus infection. Nat Commun. 2016;7:12204. doi: 10.1038/ncomms12204 27352279; PubMed Central PMCID: PMCPMC4931337.
60. Cugola FR, Fernandes IR, Russo FB, Freitas BC, Dias JL, Guimaraes KP, et al. The Brazilian Zika virus strain causes birth defects in experimental models. Nature. 2016;534(7606):267–71. doi: 10.1038/nature18296 27279226; PubMed Central PMCID: PMCPMC4902174.
61. Hirsch AJ, Smith JL, Haese NN, Broeckel RM, Parkins CJ, Kreklywich C, et al. Zika Virus infection of rhesus macaques leads to viral persistence in multiple tissues. PLoS Pathog. 2017;13(3):e1006219. doi: 10.1371/journal.ppat.1006219 28278237.
62. Tripathi S, Balasubramaniam VR, Brown JA, Mena I, Grant A, Bardina SV, et al. A novel Zika virus mouse model reveals strain specific differences in virus pathogenesis and host inflammatory immune responses. PLoS Pathog. 2017;13(3):e1006258. doi: 10.1371/journal.ppat.1006258 28278235.
63. Lazear HM, Govero J, Smith AM, Platt DJ, Fernandez E, Miner JJ, et al. A Mouse Model of Zika Virus Pathogenesis. Cell Host Microbe. 2016;19(5):720–30. doi: 10.1016/j.chom.2016.03.010 27066744; PubMed Central PMCID: PMCPMC4866885.
64. Miner JJ, Cao B, Govero J, Smith AM, Fernandez E, Cabrera OH, et al. Zika Virus Infection during Pregnancy in Mice Causes Placental Damage and Fetal Demise. Cell. 2016;165(5):1081–91. doi: 10.1016/j.cell.2016.05.008 27180225; PubMed Central PMCID: PMCPMC4874881.
65. Krow-Lucal ER, Biggerstaff BJ, Staples JE, Estimated Incubation Period for Zika Virus Disease. Emerg Infect Dis. 2017;23(5). doi: 10.3201/eid2305.161715 28277198.
66. Paz-Bailey G, Rosenberg ES, Doyle K, Munoz-Jordan J, Santiago GA, Klein L, et al. Persistence of Zika Virus in Body Fluids—Preliminary Report. N Engl J Med. 2017. doi: 10.1056/NEJMoa1613108 28195756.
67. Musso D, Roche C, Nhan TX, Robin E, Teissier A, Cao-Lormeau VM, Detection of Zika virus in saliva. J Clin Virol. 2015;68:53–5. doi: 10.1016/j.jcv.2015.04.021 26071336.
68. Mansuy JM, Mengelle C, Pasquier C, Chapuy-Regaud S, Delobel P, Martin-Blondel G, et al. Zika Virus Infection and Prolonged Viremia in Whole-Blood Specimens. Emerg Infect Dis. 2017;23(5). doi: 10.3201/eid2305.161631 28257281.
69. Bierlaire D, Mauguin S, Broult J, Musso D, Zika virus and blood transfusion: the experience of French Polynesia. Transfusion. 2017. doi: 10.1111/trf.14028 28185278.
70. Zhao H, Fernandez E, Dowd KA, Speer SD, Platt DJ, Gorman MJ, et al. Structural Basis of Zika Virus-Specific Antibody Protection. Cell. 2016;166(4):1016–27. doi: 10.1016/j.cell.2016.07.020 27475895; PubMed Central PMCID: PMCPMC4983199.
71. Sapparapu G, Fernandez E, Kose N, Bin C, Fox JM, Bombardi RG, et al. Neutralizing human antibodies prevent Zika virus replication and fetal disease in mice. Nature. 2016;540(7633):443–7. doi: 10.1038/nature20564 27819683.
72. Halstead SB, Chow JS, Marchette NJ, Immunological enhancement of dengue virus replication. Nat New Biol. 1973;243(122):24–6. 17319077.
73. Halstead SB, Marchette NJ, Sung Chow JS, Lolekha S, Dengue virus replication enhancement in peripheral blood leukocytes from immune human beings. Proc Soc Exp Biol Med. 1976;151(1):136–9. 1250839.
74. Halstead SB, O'Rourke EJ, Dengue viruses and mononuclear phagocytes. I. Infection enhancement by non-neutralizing antibody. J Exp Med. 1977;146(1):201–17. 406347; PubMed Central PMCID: PMCPMC2180729.
75. Halstead SB, In vivo enhancement of dengue virus infection in rhesus monkeys by passively transferred antibody. J Infect Dis. 1979;140(4):527–33. 117061.
76. Wen J, Tang WW, Sheets N, Ellison J, Sette A, Kim K, et al. Identification of Zika virus epitopes reveals immunodominant and protective roles for dengue virus cross-reactive CD8+ T cells. Nat Microbiol. 2017;2:17036. doi: 10.1038/nmicrobiol.2017.36 28288094.
77. Weiskopf D, Cerpas C, Angelo MA, Bangs DJ, Sidney J, Paul S, et al. Human CD8+ T-Cell Responses Against the 4 Dengue Virus Serotypes Are Associated With Distinct Patterns of Protein Targets. J Infect Dis. 2015;212(11):1743–51. doi: 10.1093/infdis/jiv289 25980035; PubMed Central PMCID: PMCPMC4633759.
78. Grifoni A, Pham J, Sidney J, O'Rourke PH, Paul S, Peters B, et al. Prior Dengue virus exposure shapes T cell immunity to Zika virus in humans. J Virol. In press.
79. Akondy RS, Monson ND, Miller JD, Edupuganti S, Teuwen D, Wu H, et al. The yellow fever virus vaccine induces a broad and polyfunctional human memory CD8+ T cell response. J Immunol. 2009;183(12):7919–30. doi: 10.4049/jimmunol.0803903 19933869; PubMed Central PMCID: PMCPMC3374958.
80. Mongkolsapaya J, Dejnirattisai W, Xu XN, Vasanawathana S, Tangthawornchaikul N, Chairunsri A, et al. Original antigenic sin and apoptosis in the pathogenesis of dengue hemorrhagic fever. Nat Med. 2003;9(7):921–7. Epub 2003/06/17. doi: 10.1038/nm887 12808447.
81. Friberg H, Bashyam H, Toyosaki-Maeda T, Potts JA, Greenough T, Kalayanarooj S, et al. Cross-reactivity and expansion of dengue-specific T cells during acute primary and secondary infections in humans. Sci Rep. 2011;1:51. Epub 2012/02/23. doi: 10.1038/srep00051 22355570; PubMed Central PMCID: PMCPMC3216538.
82. Dung NT, Duyen HT, Thuy NT, Ngoc TV, Chau NV, Hien TT, et al. Timing of CD8+ T cell responses in relation to commencement of capillary leakage in children with dengue. J Immunol. 2010;184(12):7281–7. Epub 2010/05/21. doi: 10.4049/jimmunol.0903262 20483770; PubMed Central PMCID: PMCPMC4340505.