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Volumn 15, Issue 1, 2018, Pages 11-24

The inflammatory microenvironment and microbiome in prostate cancer development

Author keywords

[No Author keywords available]

Indexed keywords

CYCLOPHOSPHAMIDE; ENZALUTAMIDE; OXALIPLATIN; REACTIVE OXYGEN METABOLITE;

EID: 85039868299     PISSN: 17594812     EISSN: 17594820     Source Type: Journal    
DOI: 10.1038/nrurol.2017.167     Document Type: Review
Times cited : (319)

References (145)
  • 1
    • 84936748884 scopus 로고    scopus 로고
    • Prostate cancer immunotherapy: Beyond immunity to curability
    • Simons, J. W. Prostate cancer immunotherapy: beyond immunity to curability. Cancer Immunol. Res. 2, 1034-1043 (2014).
    • (2014) Cancer Immunol. Res. , vol.2 , pp. 1034-1043
    • Simons, J.W.1
  • 2
    • 84928062583 scopus 로고    scopus 로고
    • Immune checkpoint blockade: A common denominator approach to cancer therapy
    • Topalian, S. L., Drake, C. G. &Pardoll, D. M. Immune checkpoint blockade: a common denominator approach to cancer therapy. Cancer Cell 27, 450-461 (2015).
    • (2015) Cancer Cell , vol.27 , pp. 450-461
    • Topalian, S.L.1    Drake, C.G.2    Pardoll, D.M.3
  • 3
    • 33947687854 scopus 로고    scopus 로고
    • Inflammation in prostate carcinogenesis
    • De Marzo, A. M. et al. Inflammation in prostate carcinogenesis. Nat. Rev. Cancer 7, 256-269 (2007).
    • (2007) Nat. Rev. Cancer , vol.7 , pp. 256-269
    • De Marzo, A.M.1
  • 5
    • 84255204457 scopus 로고    scopus 로고
    • Prostate cancer and inflammation: The evidence
    • Sfanos, K. S. &De Marzo, A. M. Prostate cancer and inflammation: the evidence. Histopathology 60, 199-215 (2012).
    • (2012) Histopathology , vol.60 , pp. 199-215
    • Sfanos, K.S.1    De Marzo, A.M.2
  • 6
    • 79952284127 scopus 로고    scopus 로고
    • Hallmarks of cancer: The next generation
    • Hanahan, D. &Weinberg, R. A. Hallmarks of cancer: the next generation. Cell 144, 646-674 (2011).
    • (2011) Cell , vol.144 , pp. 646-674
    • Hanahan, D.1    Weinberg, R.A.2
  • 8
    • 77956299351 scopus 로고    scopus 로고
    • Sexually transmitted infections and risk of prostate cancer: Review of historical and emerging hypotheses
    • Sutcliffe, S. Sexually transmitted infections and risk of prostate cancer: review of historical and emerging hypotheses. Future Oncol. 6, 1289-1311 (2010).
    • (2010) Future Oncol. , vol.6 , pp. 1289-1311
    • Sutcliffe, S.1
  • 9
    • 0346499121 scopus 로고    scopus 로고
    • Epidemiology of inflammation and prostate cancer
    • Platz, E. A. &De Marzo, A. M. Epidemiology of inflammation and prostate cancer. J. Urol. 171 (Suppl.), S36-S40 (2004).
    • (2004) J. Urol. , vol.171 , pp. S36-S40
    • Platz, E.A.1    De Marzo, A.M.2
  • 11
    • 22844438244 scopus 로고    scopus 로고
    • Prostate carcinogenesis and inflammation: Emerging insights
    • Palapattu, G. S. et al. Prostate carcinogenesis and inflammation: emerging insights. Carcinogenesis 26, 1170-1181 (2005).
    • (2005) Carcinogenesis , vol.26 , pp. 1170-1181
    • Palapattu, G.S.1
  • 12
    • 0036294342 scopus 로고    scopus 로고
    • Epidemiologic association between prostatitis and prostate cancer
    • Dennis, L. K., Lynch, C. F. &Torner, J. C. Epidemiologic association between prostatitis and prostate cancer. Urology 60, 78-83 (2002).
    • (2002) Urology , vol.60 , pp. 78-83
    • Dennis, L.K.1    Lynch, C.F.2    Torner, J.C.3
  • 13
    • 85031695024 scopus 로고    scopus 로고
    • A prospective study of chronic inflammation in benign prostate tissue and risk of prostate cancer: Linked PCPT and SELECT cohorts
    • Platz, E. A. et al. A prospective study of chronic inflammation in benign prostate tissue and risk of prostate cancer: linked PCPT and SELECT cohorts. Cancer Epidemiol. Biomarkers Prev. http://dx.doi. org/10.1158/1055-9965.EPI-17-0503 (2017).
    • (2017) Cancer Epidemiol. Biomarkers Prev
    • Platz, E.A.1
  • 14
    • 58849106753 scopus 로고    scopus 로고
    • History of the term prostate
    • Josef Marx, F. &Karenberg, A. History of the term prostate. Prostate 69, 208-213 (2009).
    • (2009) Prostate , vol.69 , pp. 208-213
    • Josef, M.F.1    Karenberg, A.2
  • 16
    • 84929029764 scopus 로고    scopus 로고
    • Intraepithelial lymphocytes in relation to NIH category IV prostatitis in autopsy prostate
    • Dikov, D., Bachurska, S., Staikov, D. &Sarafian, V. Intraepithelial lymphocytes in relation to NIH category IV prostatitis in autopsy prostate. Prostate 75, 1074-1084 (2015).
    • (2015) Prostate , vol.75 , pp. 1074-1084
    • Dikov, D.1    Bachurska, S.2    Staikov, D.3    Sarafian, V.4
  • 17
    • 44349101991 scopus 로고    scopus 로고
    • Immunomodulatory mast cells: Negative, as well as positive, regulators of immunity
    • Galli, S. J., Grimbaldeston, M. &Tsai, M. Immunomodulatory mast cells: negative, as well as positive, regulators of immunity. Nat. Rev. Immunol. 8, 478-486 (2008).
    • (2008) Nat. Rev. Immunol. , vol.8 , pp. 478-486
    • Galli, S.J.1    Grimbaldeston, M.2    Tsai, M.3
  • 18
    • 84872272400 scopus 로고    scopus 로고
    • Immunohistochemical analysis of inflammatory cells in benign and precancerous lesions and carcinoma of the prostate
    • Fujii, T. et al. Immunohistochemical analysis of inflammatory cells in benign and precancerous lesions and carcinoma of the prostate. Pathobiology 80, 119-126 (2013).
    • (2013) Pathobiology , vol.80 , pp. 119-126
    • Fujii, T.1
  • 19
    • 62549098236 scopus 로고    scopus 로고
    • Acute inflammatory proteins constitute the organic matrix of prostatic corpora amylacea and calculi in men with prostate cancer
    • Sfanos, K. S., Wilson, B. A., De Marzo, A. M. &Isaacs, W. B. Acute inflammatory proteins constitute the organic matrix of prostatic corpora amylacea and calculi in men with prostate cancer. Proc. Natl Acad. Sci. USA 106, 3443-3448 (2009).
    • (2009) Proc. Natl Acad. Sci. USA , vol.106 , pp. 3443-3448
    • Sfanos, K.S.1    Wilson, B.A.2    De Marzo, A.M.3    Isaacs, W.B.4
  • 20
    • 15244361045 scopus 로고    scopus 로고
    • Diagnosis of prostatic inflammation: Efficacy of needle biopsies versus tissue blocks
    • Difuccia, B., Keith, I., Teunissen, B. &Moon, T. Diagnosis of prostatic inflammation: efficacy of needle biopsies versus tissue blocks. Urology 65, 445-448 (2005).
    • (2005) Urology , vol.65 , pp. 445-448
    • Difuccia, B.1    Keith, I.2    Teunissen, B.3    Moon, T.4
  • 21
    • 84935066963 scopus 로고    scopus 로고
    • Immune infiltration and prostate cancer
    • Strasner, A. &Karin, M. Immune infiltration and prostate cancer. Front. Oncol. 5, 128 (2015).
    • (2015) Front. Oncol. , vol.5 , pp. 128
    • Strasner, A.1    Karin, M.2
  • 22
    • 84899746407 scopus 로고    scopus 로고
    • Chronic inflammation in benign prostate tissue is associated with high-grade prostate cancer in the placebo arm of the prostate cancer prevention trial
    • Gurel, B. et al. Chronic inflammation in benign prostate tissue is associated with high-grade prostate cancer in the placebo arm of the prostate cancer prevention trial. Cancer Epidemiol. Biomarkers Prev. 23, 847-856 (2014).
    • (2014) Cancer Epidemiol. Biomarkers Prev. , vol.23 , pp. 847-856
    • Gurel, B.1
  • 23
    • 0032715912 scopus 로고    scopus 로고
    • Asymptomatic inflammation and/or infection in benign prostatic hyperplasia
    • Nickel, J. C., Downey, J., Young, I. &Boag, S. Asymptomatic inflammation and/or infection in benign prostatic hyperplasia. BJU Int. 84, 976-981 (1999).
    • (1999) BJU Int. , vol.84 , pp. 976-981
    • Nickel, J.C.1    Downey, J.2    Young, I.3    Boag, S.4
  • 24
    • 84897567467 scopus 로고    scopus 로고
    • The role of M1 and M2 macrophages in prostate cancer in relation to extracapsular tumor extension and biochemical recurrence after radical prostatectomy
    • Lanciotti, M. et al. The role of M1 and M2 macrophages in prostate cancer in relation to extracapsular tumor extension and biochemical recurrence after radical prostatectomy. BioMed Res. Int. 2014, 6 (2014).
    • (2014) BioMed Res. Int. , vol.2014 , pp. 6
    • Lanciotti, M.1
  • 25
    • 70349485580 scopus 로고    scopus 로고
    • Human prostate-infiltrating CD8+ T lymphocytes are oligoclonal and PD-1+
    • Sfanos, K. S. et al. Human prostate-infiltrating CD8+ T lymphocytes are oligoclonal and PD-1+. Prostate 69, 1694-1703 (2009).
    • (2009) Prostate , vol.69 , pp. 1694-1703
    • Sfanos, K.S.1
  • 26
    • 37249067503 scopus 로고    scopus 로고
    • CD8+ Foxp3+ regulatory T cells mediate immunosuppression in prostate cancer
    • Kiniwa, Y. et al. CD8+ Foxp3+ regulatory T cells mediate immunosuppression in prostate cancer. Clin. Cancer Res. 13, 6947-6958 (2007).
    • (2007) Clin. Cancer Res. , vol.13 , pp. 6947-6958
    • Kiniwa, Y.1
  • 27
    • 33750807427 scopus 로고    scopus 로고
    • CD4+CD25high T cells are enriched in the tumor and peripheral blood of prostate cancer patients
    • Miller, A. M. et al. CD4+CD25high T cells are enriched in the tumor and peripheral blood of prostate cancer patients. J. Immunol. 177, 7398-7405 (2006).
    • (2006) J. Immunol. , vol.177 , pp. 7398-7405
    • Miller, A.M.1
  • 28
    • 84875209263 scopus 로고    scopus 로고
    • CD4 helper T cells, CD8 cytotoxic T cells, and FOXP3+ regulatory T cells with respect to lethal prostate cancer
    • Davidsson, S. et al. CD4 helper T cells, CD8 cytotoxic T cells, and FOXP3+ regulatory T cells with respect to lethal prostate cancer. Mod. Pathol. 26, 448-455 (2013).
    • (2013) Mod. Pathol. , vol.26 , pp. 448-455
    • Davidsson, S.1
  • 29
    • 48849103649 scopus 로고    scopus 로고
    • Phenotypic analysis of prostate-infiltrating lymphocytes reveals TH17 and Treg skewing
    • Sfanos, K. S. et al. Phenotypic analysis of prostate-infiltrating lymphocytes reveals TH17 and Treg skewing. Clin. Cancer Res. 14, 3254-3261 (2008).
    • (2008) Clin. Cancer Res. , vol.14 , pp. 3254-3261
    • Sfanos, K.S.1
  • 30
    • 84893203731 scopus 로고    scopus 로고
    • Tumor infiltrating B-cells are increased in prostate cancer tissue
    • Woo, J. R. et al. Tumor infiltrating B-cells are increased in prostate cancer tissue. J. Transl Med. 12, 1-9 (2014).
    • (2014) J. Transl Med. , vol.12 , pp. 1-9
    • Woo, J.R.1
  • 31
    • 28444496629 scopus 로고    scopus 로고
    • Tumour-infiltrating lymphocytes: A prognostic factor of PSA-free survival in patients with local prostate carcinoma treated by radical prostatectomy
    • Karja, V. et al. Tumour-infiltrating lymphocytes: a prognostic factor of PSA-free survival in patients with local prostate carcinoma treated by radical prostatectomy. Anticancer Res. 25, 4435-4438 (2005).
    • (2005) Anticancer Res. , vol.25 , pp. 4435-4438
    • Karja, V.1
  • 32
    • 84875744038 scopus 로고    scopus 로고
    • High tissue density of FOXP3+ T cells is associated with clinical outcome in prostate cancer
    • Flammiger, A. et al. High tissue density of FOXP3+ T cells is associated with clinical outcome in prostate cancer. Eur. J. Cancer 49, 1273-1279 (2012).
    • (2012) Eur. J. Cancer , vol.49 , pp. 1273-1279
    • Flammiger, A.1
  • 33
    • 77949379050 scopus 로고    scopus 로고
    • B-Cell-derived lymphotoxin promotes castration-resistant prostate cancer
    • Ammirante, M., Luo, J.-L., Grivennikov, S., Nedospasov, S. &Karin, M. B-Cell-derived lymphotoxin promotes castration-resistant prostate cancer. Nature 464, 302-305 (2010).
    • (2010) Nature , vol.464 , pp. 302-305
    • Ammirante, M.1    Luo, J.-L.2    Grivennikov, S.3    Nedospasov, S.4    Karin, M.5
  • 34
    • 84866873779 scopus 로고    scopus 로고
    • Intratumoral T but not B lymphocytes are related to clinical outcome in prostate cancer
    • Flammiger, A. et al. Intratumoral T but not B lymphocytes are related to clinical outcome in prostate cancer. APMIS 120, 901-908 (2012).
    • (2012) APMIS , vol.120 , pp. 901-908
    • Flammiger, A.1
  • 35
    • 85006515944 scopus 로고    scopus 로고
    • Low intratumoral mast cells are associated with a higher risk of prostate cancer recurrence
    • Hempel, H. A. et al. Low intratumoral mast cells are associated with a higher risk of prostate cancer recurrence. Prostate 77, 412-424 (2017).
    • (2017) Prostate , vol.77 , pp. 412-424
    • Hempel, H.A.1
  • 36
    • 0034266661 scopus 로고    scopus 로고
    • Tumor associated macrophages in human prostate cancer: Relation to clinicopathological variables and survival
    • Lissbrant, I. et al. Tumor associated macrophages in human prostate cancer: relation to clinicopathological variables and survival. Int. J. Oncol. 17, 445-451 (2000).
    • (2000) Int. J. Oncol. , vol.17 , pp. 445-451
    • Lissbrant, I.1
  • 37
    • 18244403761 scopus 로고    scopus 로고
    • Cyclooxygenase-2 expression correlates with local chronic inflammation and tumor neovascularization in human prostate cancer
    • Wang, W., Bergh, A. &Damber, J.-E. Cyclooxygenase-2 expression correlates with local chronic inflammation and tumor neovascularization in human prostate cancer. Clin. Cancer Res. 11, 3250-3256 (2005).
    • (2005) Clin. Cancer Res. , vol.11 , pp. 3250-3256
    • Wang, W.1    Bergh, A.2    Damber, J.-E.3
  • 38
    • 79957822818 scopus 로고    scopus 로고
    • Infiltration of tumour-associated macrophages in prostate biopsy specimens is predictive of disease progression after hormonal therapy for prostate cancer
    • Nonomura, N. et al. Infiltration of tumour-associated macrophages in prostate biopsy specimens is predictive of disease progression after hormonal therapy for prostate cancer. BJU Int. 107, 1918-1922 (2011).
    • (2011) BJU Int. , vol.107 , pp. 1918-1922
    • Nonomura, N.1
  • 39
    • 45549093317 scopus 로고    scopus 로고
    • The prognostic impact of M-CSF, CSF-1 receptor, CD68 and CD3 in prostatic carcinoma
    • Richardsen, E., Uglehus, R. D., Due, J., Busch, C. &Busund, L. T. R. The prognostic impact of M-CSF, CSF-1 receptor, CD68 and CD3 in prostatic carcinoma. Histopathology 53, 30-38 (2008).
    • (2008) Histopathology , vol.53 , pp. 30-38
    • Richardsen, E.1    Uglehus, R.D.2    Due, J.3    Busch, C.4    Busund, L.T.R.5
  • 40
    • 0032818610 scopus 로고    scopus 로고
    • High-grade inflammation in prostate cancer as a prognostic factor for biochemical recurrence after radical prostatectomy
    • Irani, J. et al. High-grade inflammation in prostate cancer as a prognostic factor for biochemical recurrence after radical prostatectomy. Urology 54, 467-472 (1999).
    • (1999) Urology , vol.54 , pp. 467-472
    • Irani, J.1
  • 41
    • 4143110451 scopus 로고    scopus 로고
    • The relationship between T-lymphocyte subset infiltration and survival in patients with prostate cancer
    • McArdle, P. A. et al. The relationship between T-lymphocyte subset infiltration and survival in patients with prostate cancer. Br. J. Cancer 91, 541-543 (2004).
    • (2004) Br. J. Cancer , vol.91 , pp. 541-543
    • McArdle, P.A.1
  • 42
    • 41149130863 scopus 로고    scopus 로고
    • Multiple roles for CD4+ T cells in anti-tumor immune responses
    • Kennedy, R. &Celis, E. Multiple roles for CD4+ T cells in anti-tumor immune responses. Immunol. Rev. 222, 129-144 (2008).
    • (2008) Immunol. Rev. , vol.222 , pp. 129-144
    • Kennedy, R.1    Celis, E.2
  • 43
    • 33746599842 scopus 로고    scopus 로고
    • Regulatory T cells in cancer
    • Beyer, M. &Schultze, J. L. Regulatory T cells in cancer. Blood 108, 804-811 (2006).
    • (2006) Blood , vol.108 , pp. 804-811
    • Beyer, M.1    Schultze, J.L.2
  • 45
    • 81255162523 scopus 로고    scopus 로고
    • Oxidative damage targets complexes containing DNA methyltransferases, SIRT1, and polycomb members to promoter CpG Islands
    • O'Hagan, H. M. et al. Oxidative damage targets complexes containing DNA methyltransferases, SIRT1, and polycomb members to promoter CpG Islands. Cancer Cell 20, 606-619 (2011).
    • (2011) Cancer Cell , vol.20 , pp. 606-619
    • O'Hagan, H.M.1
  • 46
    • 50849104569 scopus 로고    scopus 로고
    • Double strand breaks can initiate gene silencing and SIRT1-dependent onset of DNA methylation in an exogenous promoter CpG island
    • O'Hagan, H. M., Mohammad, H. P. &Baylin, S. B. Double strand breaks can initiate gene silencing and SIRT1-dependent onset of DNA methylation in an exogenous promoter CpG island. PLoS Genet. 4, e1000155 (2008).
    • (2008) PLoS Genet. , vol.4 , pp. e1000155
    • O'Hagan, H.M.1    Mohammad, H.P.2    Baylin, S.B.3
  • 47
    • 55349130961 scopus 로고    scopus 로고
    • DNA hypomethylation arises later in prostate cancer progression than CpG island hypermethylation and contributes to metastatic tumor heterogeneity
    • Yegnasubramanian, S. et al. DNA hypomethylation arises later in prostate cancer progression than CpG island hypermethylation and contributes to metastatic tumor heterogeneity. Cancer Res. 68, 8954-8967 (2008).
    • (2008) Cancer Res. , vol.68 , pp. 8954-8967
    • Yegnasubramanian, S.1
  • 48
    • 84872732113 scopus 로고    scopus 로고
    • DNA methylation alterations exhibit intraindividual stability and interindividual heterogeneity in prostate cancer metastases
    • Aryee, M. J. et al. DNA methylation alterations exhibit intraindividual stability and interindividual heterogeneity in prostate cancer metastases. Sci. Transl Med. 5, 169ra110 (2013).
    • (2013) Sci. Transl Med. , vol.5 , pp. 169ra110
    • Aryee, M.J.1
  • 49
    • 85002733481 scopus 로고    scopus 로고
    • Inflammation-induced oxidative stress mediates gene fusion formation in prostate cancer
    • Mani, R. S. et al. Inflammation-induced oxidative stress mediates gene fusion formation in prostate cancer. Cell Rep. 17, 2620-2631 (2016).
    • (2016) Cell Rep. , vol.17 , pp. 2620-2631
    • Mani, R.S.1
  • 50
    • 77955069195 scopus 로고    scopus 로고
    • Androgen-induced TOP2B-mediated double-strand breaks and prostate cancer gene rearrangements
    • Haffner, M. C. et al. Androgen-induced TOP2B-mediated double-strand breaks and prostate cancer gene rearrangements. Nat. Genet. 42, 668-675 (2010).
    • (2010) Nat. Genet. , vol.42 , pp. 668-675
    • Haffner, M.C.1
  • 51
    • 79959189181 scopus 로고    scopus 로고
    • Transcription-induced DNA double strand breaks: Both oncogenic force and potential therapeutic target
    • Haffner, M. C., De Marzo, A. M., Meeker, A. K., Nelson, W. G. &Yegnasubramanian, S. Transcription-induced DNA double strand breaks: both oncogenic force and potential therapeutic target? Clin. Cancer Res. 17, 3858-3864 (2011).
    • (2011) Clin. Cancer Res. , vol.17 , pp. 3858-3864
    • Haffner, M.C.1    De Marzo, A.M.2    Meeker, A.K.3    Nelson, W.G.4    Yegnasubramanian, S.5
  • 52
    • 0242417532 scopus 로고    scopus 로고
    • Intermediate cells in human prostate epithelium are enriched in proliferative inflammatory atrophy
    • van Leenders, G. J. et al. Intermediate cells in human prostate epithelium are enriched in proliferative inflammatory atrophy. Am. J. Pathol. 162, 1529-1537 (2003).
    • (2003) Am. J. Pathol. , vol.162 , pp. 1529-1537
    • Van Leenders, G.J.1
  • 53
    • 0032805744 scopus 로고    scopus 로고
    • Proliferative inflammatory atrophy of the prostate: Implications for prostatic carcinogenesis
    • De Marzo, A. M., Marchi, V. L., Epstein, J. I. &Nelson, W. G. Proliferative inflammatory atrophy of the prostate: implications for prostatic carcinogenesis. Am. J. Pathol. 155, 1985-1992 (1999).
    • (1999) Am. J. Pathol. , vol.155 , pp. 1985-1992
    • De Marzo, A.M.1    Marchi, V.L.2    Epstein, J.I.3    Nelson, W.G.4
  • 54
    • 61349167799 scopus 로고    scopus 로고
    • Increased p53 immunoreactivity in proliferative inflammatory atrophy of prostate is related to focal acute inflammation
    • Wang, W., Bergh, A. &Damber, J. E. Increased p53 immunoreactivity in proliferative inflammatory atrophy of prostate is related to focal acute inflammation. APMIS 117, 185-195 (2009).
    • (2009) APMIS , vol.117 , pp. 185-195
    • Wang, W.1    Bergh, A.2    Damber, J.E.3
  • 55
    • 0025835716 scopus 로고
    • BCL2 protein is topographically restricted in tissues characterized by apoptotic cell death
    • Hockenbery, D. M., Zutter, M., Hickey, W., Nahm, M. &Korsmeyer, S. J. BCL2 protein is topographically restricted in tissues characterized by apoptotic cell death. Proc. Natl Acad. Sci. USA 88, 6961-6965 (1991).
    • (1991) Proc. Natl Acad. Sci. USA , vol.88 , pp. 6961-6965
    • Hockenbery, D.M.1    Zutter, M.2    Hickey, W.3    Nahm, M.4    Korsmeyer, S.J.5
  • 56
    • 50249133616 scopus 로고    scopus 로고
    • Nuclear MYC protein overexpression is an early alteration in human prostate carcinogenesis
    • Gurel, B. et al. Nuclear MYC protein overexpression is an early alteration in human prostate carcinogenesis. Mod. Pathol. 21, 1156-1167 (2008).
    • (2008) Mod. Pathol. , vol.21 , pp. 1156-1167
    • Gurel, B.1
  • 57
    • 78650104069 scopus 로고    scopus 로고
    • MYC and prostate cancer
    • Koh, C. M. et al. MYC and prostate cancer. Genes Cancer 1, 617-628 (2010).
    • (2010) Genes Cancer , vol.1 , pp. 617-628
    • Koh, C.M.1
  • 58
    • 0033793927 scopus 로고    scopus 로고
    • Morphologic transitions between proliferative inflammatory atrophy and high-grade prostatic intraepithelial neoplasia
    • Putzi, M. J. &De Marzo, A. M. Morphologic transitions between proliferative inflammatory atrophy and high-grade prostatic intraepithelial neoplasia. Urology 56, 828-832 (2000).
    • (2000) Urology , vol.56 , pp. 828-832
    • Putzi, M.J.1    De Marzo, A.M.2
  • 59
    • 69449093704 scopus 로고    scopus 로고
    • Morphological transition of proliferative inflammatory atrophy to high-grade intraepithelial neoplasia and cancer in human prostate
    • Wang, W., Bergh, A. &Damber, J. E. Morphological transition of proliferative inflammatory atrophy to high-grade intraepithelial neoplasia and cancer in human prostate. Prostate 69, 1378-1386 (2009).
    • (2009) Prostate , vol.69 , pp. 1378-1386
    • Wang, W.1    Bergh, A.2    Damber, J.E.3
  • 60
    • 0041924823 scopus 로고    scopus 로고
    • Hypermethylation of the human glutathione S-transferase-φ gene (GSTP1) CpG island is present in a subset of proliferative inflammatory atrophy lesions but not in normal or hyperplastic epithelium of the prostate: A detailed study using laser-capture microdissection
    • Nakayama, M. et al. Hypermethylation of the human glutathione S-transferase-φ gene (GSTP1) CpG island is present in a subset of proliferative inflammatory atrophy lesions but not in normal or hyperplastic epithelium of the prostate: a detailed study using laser-capture microdissection. Am. J. Pathol. 163, 923-933 (2003).
    • (2003) Am. J. Pathol. , vol.163 , pp. 923-933
    • Nakayama, M.1
  • 62
    • 85002581864 scopus 로고    scopus 로고
    • Low CD38 identifies progenitor-like inflammation-associated luminal cells that can initiate human prostate cancer and predict poor outcome
    • Liu, X. et al. Low CD38 identifies progenitor-like inflammation-associated luminal cells that can initiate human prostate cancer and predict poor outcome. Cell Rep. 17, 2596-2606 (2016).
    • (2016) Cell Rep. , vol.17 , pp. 2596-2606
    • Liu, X.1
  • 64
    • 84878287971 scopus 로고    scopus 로고
    • A mouse model of chronic prostatic inflammation using a human prostate cancer-derived isolate of Propionibacterium acnes
    • Shinohara, D. B. et al. A mouse model of chronic prostatic inflammation using a human prostate cancer-derived isolate of Propionibacterium acnes. Prostate 73, 1007-1015 (2013).
    • (2013) Prostate , vol.73 , pp. 1007-1015
    • Shinohara, D.B.1
  • 65
    • 84920736254 scopus 로고    scopus 로고
    • A human prostatic bacterial isolate alters the prostatic microenvironment and accelerates prostate cancer progression
    • Simons, B. W. et al. A human prostatic bacterial isolate alters the prostatic microenvironment and accelerates prostate cancer progression. J. Pathol. 235, 478-489 (2015).
    • (2015) J. Pathol. , vol.235 , pp. 478-489
    • Simons, B.W.1
  • 66
    • 84942039125 scopus 로고    scopus 로고
    • Bacterial prostatitis enhances 2-amino-1-methyl-6-phenylimidazo[4,5-β]pyridine (PhIP)-induced cancer at multiple sites
    • Sfanos, K. S. et al. Bacterial prostatitis enhances 2-amino-1-methyl-6-phenylimidazo[4,5-β]pyridine (PhIP)-induced cancer at multiple sites. Cancer Prevention Res. 8, 683-692 (2015).
    • (2015) Cancer Prevention Res. , vol.8 , pp. 683-692
    • Sfanos, K.S.1
  • 67
    • 84893434932 scopus 로고    scopus 로고
    • Prostatic inflammation enhances basal-to-luminal differentiation and accelerates initiation of prostate cancer with a basal cell origin
    • Kwon, O.-J., Zhang, L., Ittmann, M. M. &Xin, L. Prostatic inflammation enhances basal-to-luminal differentiation and accelerates initiation of prostate cancer with a basal cell origin. Proc. Natl Acad. Sci. USA 111, E592-E600 (2014).
    • (2014) Proc. Natl Acad. Sci. USA , vol.111 , pp. E592-E600
    • Kwon, O.-J.1    Zhang, L.2    Ittmann, M.M.3    Xin, L.4
  • 68
    • 84871167017 scopus 로고    scopus 로고
    • Chronic prostatic infection and inflammation by Propionibacterium acnes in a rat prostate infection model
    • Olsson, J. et al. Chronic prostatic infection and inflammation by Propionibacterium acnes in a rat prostate infection model. PLoS ONE 7, e51434 (2012).
    • (2012) PLoS ONE , vol.7 , pp. e51434
    • Olsson, J.1
  • 69
    • 33845798351 scopus 로고    scopus 로고
    • Chronic bacterial infection and inflammation incite reactive hyperplasia in a mouse model of chronic prostatitis
    • Elkahwaji, J. E., Zhong, W., Hopkins, W. J. &Bushman, W. Chronic bacterial infection and inflammation incite reactive hyperplasia in a mouse model of chronic prostatitis. Prostate 67, 14-21 (2007).
    • (2007) Prostate , vol.67 , pp. 14-21
    • Elkahwaji, J.E.1    Zhong, W.2    Hopkins, W.J.3    Bushman, W.4
  • 70
    • 77952050350 scopus 로고    scopus 로고
    • Loss of Nkx3.1 expression in bacterial prostatitis
    • Khalili, M. et al. Loss of Nkx3.1 expression in bacterial prostatitis. Am. J. Pathol. 176, 2259-2268 (2010).
    • (2010) Am. J. Pathol. , vol.176 , pp. 2259-2268
    • Khalili, M.1
  • 71
    • 79958234229 scopus 로고    scopus 로고
    • An inducible model of abacterial prostatitis induces antigen specific inflammatory and proliferative changes in the murine prostate
    • Haverkamp, J. M. et al. An inducible model of abacterial prostatitis induces antigen specific inflammatory and proliferative changes in the murine prostate. Prostate 71, 1139-1150 (2011).
    • (2011) Prostate , vol.71 , pp. 1139-1150
    • Haverkamp, J.M.1
  • 72
    • 77954801079 scopus 로고    scopus 로고
    • Improved survival with ipilimumab in patients with metastatic melanoma
    • Hodi, F. S. et al. Improved survival with ipilimumab in patients with metastatic melanoma. N. Engl. J. Med. 363, 711-723 (2010).
    • (2010) N. Engl. J. Med. , vol.363 , pp. 711-723
    • Hodi, F.S.1
  • 73
    • 79959772576 scopus 로고    scopus 로고
    • Ipilimumab plus dacarbazine for previously untreated metastatic melanoma
    • Robert, C. et al. Ipilimumab plus dacarbazine for previously untreated metastatic melanoma. N. Engl. J. Med. 364, 2517-2526 (2011).
    • (2011) N. Engl. J. Med. , vol.364 , pp. 2517-2526
    • Robert, C.1
  • 74
    • 84929481481 scopus 로고    scopus 로고
    • Pembrolizumab versus ipilimumab in advanced melanoma
    • Robert, C. et al. Pembrolizumab versus ipilimumab in advanced melanoma. N. Engl. J. Med. 372, 2521-2532 (2015).
    • (2015) N. Engl. J. Med. , vol.372 , pp. 2521-2532
    • Robert, C.1
  • 75
    • 84925222119 scopus 로고    scopus 로고
    • Nivolumab in previously untreated melanoma without BRAF mutation
    • Robert, C. et al. Nivolumab in previously untreated melanoma without BRAF mutation. N. Engl. J. Med. 372, 320-330 (2015).
    • (2015) N. Engl. J. Med. , vol.372 , pp. 320-330
    • Robert, C.1
  • 76
    • 84931083080 scopus 로고    scopus 로고
    • Nivolumab versus chemotherapy in patients with advanced melanoma who progressed after anti-CTLA-4 treatment (CheckMate 037): A randomised, controlled, open-label, phase 3 trial
    • Weber, J. S. et al. Nivolumab versus chemotherapy in patients with advanced melanoma who progressed after anti-CTLA-4 treatment (CheckMate 037): a randomised, controlled, open-label, phase 3 trial. Lancet Oncol. 16, 375-384 (2015).
    • (2015) Lancet Oncol. , vol.16 , pp. 375-384
    • Weber, J.S.1
  • 77
    • 84946607195 scopus 로고    scopus 로고
    • Nivolumab versus everolimus in advanced renal-cell carcinoma
    • Motzer, R. J. et al. Nivolumab versus everolimus in advanced renal-cell carcinoma. N. Engl. J. Med. 373, 1803-1813 (2015).
    • (2015) N. Engl. J. Med. , vol.373 , pp. 1803-1813
    • Motzer, R.J.1
  • 78
    • 84936791837 scopus 로고    scopus 로고
    • Nivolumab versus docetaxel in advanced squamous-cell non-small-cell lung cancer
    • Brahmer, J. et al. Nivolumab versus docetaxel in advanced squamous-cell non-small-cell lung cancer. N. Engl. J. Med. 373, 123-135 (2015).
    • (2015) N. Engl. J. Med. , vol.373 , pp. 123-135
    • Brahmer, J.1
  • 79
    • 84944937210 scopus 로고    scopus 로고
    • Nivolumab versus docetaxel in advanced nonsquamous non-small-cell lung cancer
    • Borghaei, H. et al. Nivolumab versus docetaxel in advanced nonsquamous non-small-cell lung cancer. N. Engl. J. Med. 373, 1627-1639 (2015).
    • (2015) N. Engl. J. Med. , vol.373 , pp. 1627-1639
    • Borghaei, H.1
  • 80
    • 68549135290 scopus 로고    scopus 로고
    • Integrated data from 2 randomized, double-blind, placebo-controlled, phase 3 trials of active cellular immunotherapy with sipuleucel-T in advanced prostate cancer
    • Higano, C. S. et al. Integrated data from 2 randomized, double-blind, placebo-controlled, phase 3 trials of active cellular immunotherapy with sipuleucel-T in advanced prostate cancer. Cancer 115, 3670-3679 (2009).
    • (2009) Cancer , vol.115 , pp. 3670-3679
    • Higano, C.S.1
  • 81
    • 77955066199 scopus 로고    scopus 로고
    • Sipuleucel-T immunotherapy for castration-resistant prostate cancer
    • Kantoff, P. W. et al. Sipuleucel-T immunotherapy for castration-resistant prostate cancer. N. Engl. J. Med. 363, 411-422 (2010).
    • (2010) N. Engl. J. Med. , vol.363 , pp. 411-422
    • Kantoff, P.W.1
  • 82
    • 77954899030 scopus 로고    scopus 로고
    • Phase i study of single-agent anti-programmed death-1 (MDX-1106) in refractory solid tumors: Safety, clinical activity, pharmacodynamics, and immunologic correlates
    • Brahmer, J. R. et al. Phase I study of single-agent anti-programmed death-1 (MDX-1106) in refractory solid tumors: safety, clinical activity, pharmacodynamics, and immunologic correlates. J. Clin. Oncol. 28, 3167-3175 (2010).
    • (2010) J. Clin. Oncol. , vol.28 , pp. 3167-3175
    • Brahmer, J.R.1
  • 83
    • 84901641673 scopus 로고    scopus 로고
    • Ipilimumab versus placebo after radiotherapy in patients with metastatic castration-resistant prostate cancer that had progressed after docetaxel chemotherapy (CA184-043): A multicentre, randomised, double-blind, phase 3 trial
    • Kwon, E. D. et al. Ipilimumab versus placebo after radiotherapy in patients with metastatic castration-resistant prostate cancer that had progressed after docetaxel chemotherapy (CA184-043): a multicentre, randomised, double-blind, phase 3 trial. Lancet Oncol. 15, 700-712 (2014).
    • (2014) Lancet Oncol. , vol.15 , pp. 700-712
    • Kwon, E.D.1
  • 84
    • 84862859820 scopus 로고    scopus 로고
    • Safety, activity, and immune correlates of anti-PD-1 antibody in cancer
    • Topalian, S. L. et al. Safety, activity, and immune correlates of anti-PD-1 antibody in cancer. N. Engl. J. Med. 366, 2443-2454 (2012).
    • (2012) N. Engl. J. Med. , vol.366 , pp. 2443-2454
    • Topalian, S.L.1
  • 85
    • 84960500773 scopus 로고    scopus 로고
    • Castration influences intestinal microflora and induces abdominal obesity in high-fat diet-fed mice
    • Harada, N. et al. Castration influences intestinal microflora and induces abdominal obesity in high-fat diet-fed mice. Sci. Rep. 6, 23001 (2016).
    • (2016) Sci. Rep. , vol.6 , pp. 23001
    • Harada, N.1
  • 86
    • 84893172969 scopus 로고    scopus 로고
    • Impact of pelvic radiotherapy on gut microbiota of gynecological cancer patients revealed by massive pyrosequencing
    • Nam, Y.-D., Kim, H. J., Seo, J.-G., Kang, S. W. &Bae, J.-W. Impact of pelvic radiotherapy on gut microbiota of gynecological cancer patients revealed by massive pyrosequencing. PLoS ONE 8, e82659 (2013).
    • (2013) PLoS ONE , vol.8 , pp. e82659
    • Nam, Y.-D.1    Kim, H.J.2    Seo, J.-G.3    Kang, S.W.4    Bae, J.-W.5
  • 87
    • 84858800620 scopus 로고    scopus 로고
    • The immune contexture in human tumours: Impact on clinical outcome
    • Fridman, W. H., Pagès, F., Sautès-Fridman, C. &Galon, J. The immune contexture in human tumours: impact on clinical outcome. Nat. Rev. Cancer 12, 298-306 (2012).
    • (2012) Nat. Rev. Cancer , vol.12 , pp. 298-306
    • Fridman, W.H.1    Pagès, F.2    Sautès-Fridman, C.3    Galon, J.4
  • 88
    • 84866852663 scopus 로고    scopus 로고
    • Cancer classification using the Immunoscore: A worldwide task force
    • Galon, J. et al. Cancer classification using the Immunoscore: a worldwide task force. J. Transl Med. 10, 205-205 (2012).
    • (2012) J. Transl Med. , vol.10 , pp. 205
    • Galon, J.1
  • 89
    • 84890280907 scopus 로고    scopus 로고
    • Towards the introduction of the 'Immunoscore' in the classification of malignant tumours
    • Galon, J. et al. Towards the introduction of the 'Immunoscore' in the classification of malignant tumours. J. Pathol. 232, 199-209 (2014).
    • (2014) J. Pathol. , vol.232 , pp. 199-209
    • Galon, J.1
  • 90
    • 84948581918 scopus 로고    scopus 로고
    • Immunoscore: A new possible approach for melanoma classification [abstract]
    • Capone, M. et al. Immunoscore: a new possible approach for melanoma classification [abstract]. J. Immunother. Cancer 2 (Suppl. 3), P193 (2014).
    • (2014) J. Immunother. Cancer , vol.2 , pp. P193
    • Capone, M.1
  • 91
    • 84982267373 scopus 로고    scopus 로고
    • Early evidence of anti-PD-1 activity in enzalutamide-resistant prostate cancer
    • Graff, J. N. et al. Early evidence of anti-PD-1 activity in enzalutamide-resistant prostate cancer. Oncotarget 7, 52810-52817 (2016).
    • (2016) Oncotarget , vol.7 , pp. 52810-52817
    • Graff, J.N.1
  • 92
    • 84921371152 scopus 로고    scopus 로고
    • PD-L1 is highly expressed in Enzalutamide resistant prostate cancer
    • Bishop, J. L. et al. PD-L1 is highly expressed in Enzalutamide resistant prostate cancer. Oncotarget 6, 234-242 (2015).
    • (2015) Oncotarget , vol.6 , pp. 234-242
    • Bishop, J.L.1
  • 93
    • 84947031227 scopus 로고    scopus 로고
    • Paucity of PD-L1 expression in prostate cancer: Innate and adaptive immune resistance
    • Martin, A. M. et al. Paucity of PD-L1 expression in prostate cancer: innate and adaptive immune resistance. Prostate Cancer Prostat. Dis. 18, 325-332 (2015).
    • (2015) Prostate Cancer Prostat. Dis. , vol.18 , pp. 325-332
    • Martin, A.M.1
  • 94
    • 84967166401 scopus 로고    scopus 로고
    • The immune checkpoint regulator PD-L1 is highly expressed in aggressive primary prostate cancer
    • Gevensleben, H. et al. The immune checkpoint regulator PD-L1 is highly expressed in aggressive primary prostate cancer. Clin. Cancer Res. 22, 1969-1977 (2016).
    • (2016) Clin. Cancer Res. , vol.22 , pp. 1969-1977
    • Gevensleben, H.1
  • 96
    • 65849449107 scopus 로고    scopus 로고
    • Prostate cancer lesions are surrounded by FOXP3+, PD-1+ and B7-H1+ lymphocyte clusters
    • Ebelt, K. et al. Prostate cancer lesions are surrounded by FOXP3+, PD-1+ and B7-H1+ lymphocyte clusters. Eur. J. Cancer 45, 1664-1672 (2009).
    • (2009) Eur. J. Cancer , vol.45 , pp. 1664-1672
    • Ebelt, K.1
  • 97
    • 16844379997 scopus 로고    scopus 로고
    • Immunosuppressive networks in the tumour environment and their therapeutic relevance
    • Zou, W. Immunosuppressive networks in the tumour environment and their therapeutic relevance. Nat. Rev. Cancer 5, 263-274 (2005).
    • (2005) Nat. Rev. Cancer , vol.5 , pp. 263-274
    • Zou, W.1
  • 98
    • 84948461699 scopus 로고    scopus 로고
    • Anticancer immunotherapy by CTLA-4 blockade relies on the gut microbiota
    • Vétizou, M. et al. Anticancer immunotherapy by CTLA-4 blockade relies on the gut microbiota. Science 350, 1079-1084 (2015).
    • (2015) Science , vol.350 , pp. 1079-1084
    • Vétizou, M.1
  • 99
    • 84888049920 scopus 로고    scopus 로고
    • Commensal bacteria control cancer response to therapy by modulating the tumor microenvironment
    • Iida, N. et al. Commensal bacteria control cancer response to therapy by modulating the tumor microenvironment. Science 342, 967-970 (2013).
    • (2013) Science , vol.342 , pp. 967-970
    • Iida, N.1
  • 100
    • 84888059687 scopus 로고    scopus 로고
    • The intestinal microbiota modulates the anticancer immune effects of cyclophosphamide
    • Viaud, S. et al. The intestinal microbiota modulates the anticancer immune effects of cyclophosphamide. Science 342, 971-976 (2013).
    • (2013) Science , vol.342 , pp. 971-976
    • Viaud, S.1
  • 101
    • 84948451779 scopus 로고    scopus 로고
    • Commensal Bifidobacterium promotes antitumor immunity and facilitates anti-PD-L1 efficacy
    • Sivan, A. et al. Commensal Bifidobacterium promotes antitumor immunity and facilitates anti-PD-L1 efficacy. Science 350, 1084-1089 (2015).
    • (2015) Science , vol.350 , pp. 1084-1089
    • Sivan, A.1
  • 103
    • 84896851032 scopus 로고    scopus 로고
    • Intestinal epithelial cells: Regulators of barrier function and immune homeostasis
    • Peterson, L. W. &Artis, D. Intestinal epithelial cells: regulators of barrier function and immune homeostasis. Nat. Rev. Immunol. 14, 141-153 (2014).
    • (2014) Nat. Rev. Immunol. , vol.14 , pp. 141-153
    • Peterson, L.W.1    Artis, D.2
  • 104
    • 69449085375 scopus 로고    scopus 로고
    • Expression of Toll-like receptor 4 in the prostate gland and its association with the severity of prostate cancer
    • Gatti, G. et al. Expression of Toll-like receptor 4 in the prostate gland and its association with the severity of prostate cancer. Prostate 69, 1387-1397 (2009).
    • (2009) Prostate , vol.69 , pp. 1387-1397
    • Gatti, G.1
  • 105
    • 84879479610 scopus 로고    scopus 로고
    • Toll-like receptors in prostate infection and cancer between bench and bedside
    • Gambara, G. et al. Toll-like receptors in prostate infection and cancer between bench and bedside. J. Cell. Mol. Med. 17, 713-722 (2013).
    • (2013) J. Cell. Mol. Med. , vol.17 , pp. 713-722
    • Gambara, G.1
  • 106
    • 84874869057 scopus 로고    scopus 로고
    • Proteolysis of complement factors iC3b and C5 by the serine protease prostate-specific antigen in prostatic fluid and seminal plasma
    • Manning, M. L., Williams, S. A., Jelinek, C. A., Kostova, M. B. &Denmeade, S. R. Proteolysis of complement factors iC3b and C5 by the serine protease prostate-specific antigen in prostatic fluid and seminal plasma. J. Immunol. 190, 2567-2574 (2013).
    • (2013) J. Immunol. , vol.190 , pp. 2567-2574
    • Manning, M.L.1    Williams, S.A.2    Jelinek, C.A.3    Kostova, M.B.4    Denmeade, S.R.5
  • 107
    • 0021345699 scopus 로고
    • Longitudinal studies of prostatic fluid immunoglobulin in men with bacterial prostatitis
    • Fowler, J. E. Jr &Mariano, M. Longitudinal studies of prostatic fluid immunoglobulin in men with bacterial prostatitis. J. Urol. 131, 363-369 (1984).
    • (1984) J. Urol. , vol.131 , pp. 363-369
    • Fowler, J.E.1    Mariano, M.2
  • 108
    • 0020966002 scopus 로고
    • Prostatic structure and function in relation to the etiology of prostatic cancer
    • Isaacs, J. T. Prostatic structure and function in relation to the etiology of prostatic cancer. Prostate 4, 351-366 (1983).
    • (1983) Prostate , vol.4 , pp. 351-366
    • Isaacs, J.T.1
  • 109
    • 0019752563 scopus 로고
    • Antibacterial substances in prostatic fluid
    • Fair, W. R. &Parrish, R. F. Antibacterial substances in prostatic fluid. Prog. Clin. Biol. Res. 75A, 247-264 (1981).
    • (1981) Prog. Clin. Biol. Res. , vol.75 A , pp. 247-264
    • Fair, W.R.1    Parrish, R.F.2
  • 110
    • 50649095929 scopus 로고    scopus 로고
    • The evaluation of markers of prostatic inflammation and function of the prostate gland in patients with chronic prostatitis
    • Zdrodowska-Stefanow, B., Ostaszewska-Puchalska, I., Badyda, J. &Galewska, Z. The evaluation of markers of prostatic inflammation and function of the prostate gland in patients with chronic prostatitis. Arch. Immunol. Ther. Exp. 56, 277-282 (2008).
    • (2008) Arch. Immunol. Ther. Exp. , vol.56 , pp. 277-282
    • Zdrodowska-Stefanow, B.1    Ostaszewska-Puchalska, I.2    Badyda, J.3    Galewska, Z.4
  • 111
    • 0017260069 scopus 로고
    • Prostatic antibacterial factor identity and significance
    • Fair, W. R., Couch, J. &Wehner, N. Prostatic antibacterial factor identity and significance. Urology 7, 169-177 (1976).
    • (1976) Urology , vol.7 , pp. 169-177
    • Fair, W.R.1    Couch, J.2    Wehner, N.3
  • 112
  • 113
    • 33645959819 scopus 로고    scopus 로고
    • Sexually transmitted infections and prostatic inflammation/cell damage as measured by serum prostate specific antigen concentration
    • Sutcliffe, S. et al. Sexually transmitted infections and prostatic inflammation/cell damage as measured by serum prostate specific antigen concentration. J. Urol. 175, 1937-1942 (2006).
    • (2006) J. Urol. , vol.175 , pp. 1937-1942
    • Sutcliffe, S.1
  • 114
    • 80052035390 scopus 로고    scopus 로고
    • Prostate involvement during sexually transmitted infections as measured by prostate-specific antigen concentration
    • Sutcliffe, S. et al. Prostate involvement during sexually transmitted infections as measured by prostate-specific antigen concentration. Br. J. Cancer 105, 602-605 (2011).
    • (2011) Br. J. Cancer , vol.105 , pp. 602-605
    • Sutcliffe, S.1
  • 115
    • 85023624892 scopus 로고    scopus 로고
    • Insight into infection-mediated prostate damage: Contrasting patterns of C-reactive protein and prostate-specific antigen levels during infection
    • Milbrandt, M. et al. Insight into infection-mediated prostate damage: contrasting patterns of C-reactive protein and prostate-specific antigen levels during infection. Prostate 77, 1325-1334 (2017).
    • (2017) Prostate , vol.77 , pp. 1325-1334
    • Milbrandt, M.1
  • 116
    • 39449096413 scopus 로고    scopus 로고
    • A molecular analysis of prokaryotic and viral DNA sequences in prostate tissue from patients with prostate cancer indicates the presence of multiple and diverse microorganisms
    • Sfanos, K. S. et al. A molecular analysis of prokaryotic and viral DNA sequences in prostate tissue from patients with prostate cancer indicates the presence of multiple and diverse microorganisms. Prostate 68, 306-320 (2008).
    • (2008) Prostate , vol.68 , pp. 306-320
    • Sfanos, K.S.1
  • 117
    • 18744374912 scopus 로고    scopus 로고
    • Propionibacterium acnes associated with inflammation in radical prostatectomy specimens: A possible link to cancer evolution
    • Cohen, R. J., Shannon, B. A., McNeal, J. E., Shannon, T. &Garrett, K. L. Propionibacterium acnes associated with inflammation in radical prostatectomy specimens: a possible link to cancer evolution? J. Urol. 173, 1969-1974 (2005).
    • (2005) J. Urol. , vol.173 , pp. 1969-1974
    • Cohen, R.J.1    Shannon, B.A.2    McNeal, J.E.3    Shannon, T.4    Garrett, K.L.5
  • 118
    • 85027942488 scopus 로고    scopus 로고
    • Multilocus sequence typing (MLST) analysis of Propionibacterium acnes isolates from radical prostatectomy specimens
    • Mak, T. N., Yu, S. H., De Marzo, A. M., Bruggemann, H. &Sfanos, K. S. Multilocus sequence typing (MLST) analysis of Propionibacterium acnes isolates from radical prostatectomy specimens. Prostate 73, 770-777 (2013).
    • (2013) Prostate , vol.73 , pp. 770-777
    • Mak, T.N.1    Yu, S.H.2    De Marzo, A.M.3    Bruggemann, H.4    Sfanos, K.S.5
  • 119
    • 51649097709 scopus 로고    scopus 로고
    • An evaluation of PCR primer sets used for detection of Propionibacterium acnes in prostate tissue samples
    • Sfanos, K. S. &Isaacs, W. B. An evaluation of PCR primer sets used for detection of Propionibacterium acnes in prostate tissue samples. Prostate 68, 1492-1495 (2008).
    • (2008) Prostate , vol.68 , pp. 1492-1495
    • Sfanos, K.S.1    Isaacs, W.B.2
  • 120
    • 65949116826 scopus 로고    scopus 로고
    • Amyloid formation by the pro-inflammatory S100A8/A9 proteins in the ageing prostate
    • Yanamandra, K. et al. Amyloid formation by the pro-inflammatory S100A8/A9 proteins in the ageing prostate. PLoS ONE 4, e5562 (2009).
    • (2009) PLoS ONE , vol.4 , pp. e5562
    • Yanamandra, K.1
  • 121
    • 53349153179 scopus 로고    scopus 로고
    • Sexually transmissible infections and prostate cancer risk
    • Huang, W.-Y. et al. Sexually transmissible infections and prostate cancer risk. Cancer Epidemiol., Biomarkers Prevention 17, 2374-2381 (2008).
    • (2008) Cancer Epidemiol., Biomarkers Prevention , vol.17 , pp. 2374-2381
    • Huang, W.-Y.1
  • 122
    • 22044443626 scopus 로고    scopus 로고
    • Prostate cancer and sexually transmitted diseases: A meta-analysis
    • Taylor, M. L., Mainous, A. G. 3 rd &Wells, B. J. Prostate cancer and sexually transmitted diseases: a meta-analysis. Family Med. 37, 506-512 (2005).
    • (2005) Family Med. , vol.37 , pp. 506-512
    • Taylor, M.L.1    Mainous, A.G.2    Wells, B.J.3
  • 123
    • 33744750202 scopus 로고    scopus 로고
    • Plasma antibodies against Trichomonas vaginalis and subsequent risk of prostate cancer
    • Sutcliffe, S. et al. Plasma antibodies against Trichomonas vaginalis and subsequent risk of prostate cancer. Cancer Epidemiol. Biomarkers Prev. 15, 939-945 (2006).
    • (2006) Cancer Epidemiol. Biomarkers Prev. , vol.15 , pp. 939-945
    • Sutcliffe, S.1
  • 124
    • 34548060310 scopus 로고    scopus 로고
    • Plasma antibodies against Chlamydia trachomatis, Human Papillomavirus, and Human Herpesvirus Type 8 in relation to prostate cancer: A prospective study
    • Sutcliffe, S. et al. Plasma antibodies against Chlamydia trachomatis, Human Papillomavirus, and Human Herpesvirus Type 8 in relation to prostate cancer: a prospective study. Cancer Epidemiol. Biomarkers Prev. 16, 1573-1580 (2007).
    • (2007) Cancer Epidemiol. Biomarkers Prev. , vol.16 , pp. 1573-1580
    • Sutcliffe, S.1
  • 125
    • 20944450872 scopus 로고    scopus 로고
    • Chlamydial antibodies and risk of prostate cancer
    • Anttila, T. et al. Chlamydial antibodies and risk of prostate cancer. Cancer Epidemiol. Biomarkers Prev. 14, 385-389 (2005).
    • (2005) Cancer Epidemiol. Biomarkers Prev. , vol.14 , pp. 385-389
    • Anttila, T.1
  • 127
    • 85038259776 scopus 로고    scopus 로고
    • The urinary microbiota of men and women and its changes in women during bacterial vaginosis and antibiotic treatment
    • Gottschick, C. et al. The urinary microbiota of men and women and its changes in women during bacterial vaginosis and antibiotic treatment. Microbiome 5, 99 (2017).
    • (2017) Microbiome , vol.5 , pp. 99
    • Gottschick, C.1
  • 128
    • 84908309816 scopus 로고    scopus 로고
    • The female urinary microbiome: A comparison of women with and without urgency urinary incontinence
    • Pearce, M. M. et al. The female urinary microbiome: a comparison of women with and without urgency urinary incontinence. mBio 5, e01283-14 (2014).
    • (2014) MBio , vol.5 , pp. e01283-e01314
    • Pearce, M.M.1
  • 129
    • 84894541568 scopus 로고    scopus 로고
    • Urine is not sterile: Use of enhanced urine culture techniques to detect resident bacterial flora in the adult female bladder
    • Hilt, E. E. et al. Urine is not sterile: use of enhanced urine culture techniques to detect resident bacterial flora in the adult female bladder. J. Clin. Microbiol. 52, 871-876 (2014).
    • (2014) J. Clin. Microbiol. , vol.52 , pp. 871-876
    • Hilt, E.E.1
  • 130
    • 78649642421 scopus 로고    scopus 로고
    • Characteristic male urine microbiomes associate with asymptomatic sexually tansmitted infection
    • Nelson, D. E. et al. Characteristic male urine microbiomes associate with asymptomatic sexually tansmitted infection. PLoS ONE 5, e14116 (2010).
    • (2010) PLoS ONE , vol.5 , pp. e14116
    • Nelson, D.E.1
  • 131
    • 84860997726 scopus 로고    scopus 로고
    • Bacterial communities of the coronal sulcus and distal urethra of adolescent males
    • Nelson, D. E. et al. Bacterial communities of the coronal sulcus and distal urethra of adolescent males. PLoS ONE 7, e36298 (2012).
    • (2012) PLoS ONE , vol.7 , pp. e36298
    • Nelson, D.E.1
  • 133
    • 84953837997 scopus 로고    scopus 로고
    • Assessment of the lower urinary tract microbiota during symptom flare in women with urologic chronic pelvic pain syndrome: A MAPP network study
    • Nickel, J. C. et al. Assessment of the lower urinary tract microbiota during symptom flare in women with urologic chronic pelvic pain syndrome: a MAPP network study. J. Urol. 195, 356-362 (2015).
    • (2015) J. Urol. , vol.195 , pp. 356-362
    • Nickel, J.C.1
  • 134
    • 79955941309 scopus 로고    scopus 로고
    • The microbial communities in male first catch urine are highly similar to those in paired urethral swab specimens
    • Dong, Q. et al. The microbial communities in male first catch urine are highly similar to those in paired urethral swab specimens. PLoS ONE 6, e19709 (2011).
    • (2011) PLoS ONE , vol.6 , pp. e19709
    • Dong, Q.1
  • 135
    • 40949102253 scopus 로고    scopus 로고
    • Clinical significance of nontraditional bacterial uropathogens in the management of chronic prostatitis
    • Nickel, J. C. &Xiang, J. Clinical significance of nontraditional bacterial uropathogens in the management of chronic prostatitis. J. Urol. 179, 1391-1395 (2008).
    • (2008) J. Urol. , vol.179 , pp. 1391-1395
    • Nickel, J.C.1    Xiang, J.2
  • 136
    • 84865339168 scopus 로고    scopus 로고
    • Integrated next-generation sequencing of 16S rDNA and metaproteomics differentiate the healthy urine microbiome from asymptomatic bacteriuria in neuropathic bladder associated with spinal cord injury
    • Fouts, D. E. et al. Integrated next-generation sequencing of 16S rDNA and metaproteomics differentiate the healthy urine microbiome from asymptomatic bacteriuria in neuropathic bladder associated with spinal cord injury. J. Transl Med. 10, 174 (2012).
    • (2012) J. Transl Med. , vol.10 , pp. 174
    • Fouts, D.E.1
  • 137
    • 85034098046 scopus 로고    scopus 로고
    • Profiling the urinary microbiome in men with positive versus negative biopsies for prostate cancer
    • Shrestha, E. et al. Profiling the urinary microbiome in men with positive versus negative biopsies for prostate cancer. J. Urol. http://dx.doi.org/10.1016/j. juro.2017.08.001 (2017).
    • (2017) J. Urol.
    • Shrestha, E.1
  • 138
    • 84975266712 scopus 로고    scopus 로고
    • Frequency and typing of Propionibacterium acnes in prostate tissue obtained from men with and without prostate cancer
    • Davidsson, S. et al. Frequency and typing of Propionibacterium acnes in prostate tissue obtained from men with and without prostate cancer. Infect. Agent. Cancer 11, 26 (2016).
    • (2016) Infect. Agent. Cancer , vol.11 , pp. 26
    • Davidsson, S.1
  • 139
    • 84953361711 scopus 로고    scopus 로고
    • Search for microorganisms in men with urologic chronic pelvic pain syndrome: A culture-independent analysis in the MAPP research network
    • Nickel, J. C. et al. Search for microorganisms in men with urologic chronic pelvic pain syndrome: a culture-independent analysis in the MAPP research network. J. Urol. 194, 127-135 (2015).
    • (2015) J. Urol. , vol.194 , pp. 127-135
    • Nickel, J.C.1
  • 140
    • 84961773576 scopus 로고    scopus 로고
    • Discovery of a novel seminal fluid microbiome and influence of estrogen receptor alpha genetic status
    • Javurek, A. B. et al. Discovery of a novel seminal fluid microbiome and influence of estrogen receptor alpha genetic status. Sci. Rep. 6, 23027 (2016).
    • (2016) Sci. Rep. , vol.6 , pp. 23027
    • Javurek, A.B.1
  • 141
    • 84942815745 scopus 로고    scopus 로고
    • Decreased microbiota diversity associated with urinary tract infection in a trial of bacterial interference
    • Horwitz, D. et al. Decreased microbiota diversity associated with urinary tract infection in a trial of bacterial interference. J. Infect. 71, 358-367 (2015).
    • (2015) J. Infect. , vol.71 , pp. 358-367
    • Horwitz, D.1
  • 142
    • 84904561115 scopus 로고    scopus 로고
    • Sexually transmitted infections and prostate cancer risk: A systematic review and meta-analysis
    • Caini, S. et al. Sexually transmitted infections and prostate cancer risk: a systematic review and meta-analysis. Cancer Epidemiol. 38, 329-338 (2014).
    • (2014) Cancer Epidemiol. , vol.38 , pp. 329-338
    • Caini, S.1
  • 143
    • 0020452277 scopus 로고
    • Intra-prostatic urinary reflux: An aetiological factor in abacterial prostatitis
    • Kirby, R. S., Lowe, D., Bultitude, M. I. &Shuttleworth, K. E. Intra-prostatic urinary reflux: an aetiological factor in abacterial prostatitis. Br. J. Urol. 54, 729-731 (1982).
    • (1982) Br. J. Urol. , vol.54 , pp. 729-731
    • Kirby, R.S.1    Lowe, D.2    Bultitude, M.I.3    Shuttleworth, K.E.4
  • 144
    • 84928399740 scopus 로고    scopus 로고
    • Urinary microbiota in patients with prostate cancer and benign prostatic hyperplasia
    • Yu, H. et al. Urinary microbiota in patients with prostate cancer and benign prostatic hyperplasia. Arch. Med. Sci. 11, 385-394 (2015).
    • (2015) Arch. Med. Sci. , vol.11 , pp. 385-394
    • Yu, H.1
  • 145
    • 79957902715 scopus 로고    scopus 로고
    • Acute Escherichia coli prostatitis in previously health young men: Bacterial virulence factors, antimicrobial resistance, and clinical outcomes
    • Krieger, J. N., Dobrindt, U., Riley, D. E. &Oswald, E. Acute Escherichia coli prostatitis in previously health young men: bacterial virulence factors, antimicrobial resistance, and clinical outcomes. Urology 77, 1420-1425 (2011).
    • (2011) Urology , vol.77 , pp. 1420-1425
    • Krieger, J.N.1    Dobrindt, U.2    Riley, D.E.3    Oswald, E.4


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