Chronic Prostatic Infection and Inflammation by Propionibacterium acnes in a Rat Prostate Infection Model

PLoS ONE

Volumn 7, Issue 12, 2012, Pages

  Olsson, Jan ^a   Drott, Johanna Bergh ^a   Laurantzon, Lovisa ^a   Laurantzon, Oscar ^a   Bergh, Anders ^a   Elgh, Fredrik ^a  

^a UMEÅ UNIVERSITY   (Sweden)

Author keywords

[No Author keywords available]

Indexed keywords

C REACTIVE PROTEIN; IMMUNOGLOBULIN G;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BACTERIAL CLEARANCE; BACTERIAL COUNT; BACTERIAL VIRULENCE; BACTERIUM COLONY; BLOOD ANALYSIS; CHRONIC INFLAMMATION; CHRONIC PROSTATITIS; CONTROLLED STUDY; DISEASE SEVERITY; HISTOPATHOLOGY; MALE; NONHUMAN; PROPIONIBACTERIUM ACNES; PROSTATE VENTRAL LOBE; RAT; SEROLOGY; TISSUE CHARACTERIZATION;

ANIMALS; ANTIGENS, BACTERIAL; CHRONIC DISEASE; DISEASE MODELS, ANIMAL; HUMANS; IMMUNOGLOBULIN G; INFLAMMATION; MALE; PROPIONIBACTERIUM ACNES; PROSTATE; PROSTATIC DISEASES; PROSTATIC HYPERPLASIA; RATS; RATS, SPRAGUE-DAWLEY;

BACTERIA (MICROORGANISMS); POSIBACTERIA; PROPIONIBACTERIUM ACNES; RATTUS;

EID: 84871167017     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0051434     Document Type: Article

References (32)

1. Delongchamps NB, de la Roza G, Chandan V, Jones R, Sunheimer R, et al. (2008) Evaluation of prostatitis in autopsied prostates-is chronic inflammation more associated with benign prostatic hyperplasia or cancer? The Journal of urology 179: 1736-1740.
2. Nickel JC (2008) Inflammation and benign prostatic hyperplasia. Urol Clin North Am 35: 109-115; vii.
3. Colotta F, Allavena P, Sica A, Garlanda C, Mantovani A, (2009) Cancer-related inflammation, the seventh hallmark of cancer: links to genetic instability. Carcinogenesis 30: 1073-1081.
4. De Marzo AM, Marchi VL, Epstein JI, Nelson WG, (1999) Proliferative inflammatory atrophy of the prostate: implications for prostatic carcinogenesis. The American journal of pathology 155: 1985-1992.
5. Palapattu GS, Sutcliffe S, Bastian PJ, Platz EA, De Marzo AM, et al. (2005) Prostate carcinogenesis and inflammation: emerging insights. Carcinogenesis 26: 1170-1181.
6. Kramer G, Mitteregger D, Marberger M, (2007) Is benign prostatic hyperplasia (BPH) an immune inflammatory disease? European urology 51: 1202-1216.
7. Sutcliffe S, Platz EA, (2008) Inflammation and prostate cancer: a focus on infections. Curr Urol Rep 9: 243-249.
8. Cheng I, Witte JS, Jacobsen SJ, Haque R, Quinn VP, et al. (2010) Prostatitis, sexually transmitted diseases, and prostate cancer: the California Men's Health Study. PLoS One 5: e8736.
9. Nickel JC, Xiang J, (2008) Clinical significance of nontraditional bacterial uropathogens in the management of chronic prostatitis. J Urol 179: 1391-1395.
10. Hochreiter WW, Duncan JL, Schaeffer AJ, (2000) Evaluation of the bacterial flora of the prostate using a 16S rRNA gene based polymerase chain reaction. J Urol 163: 127-130.
11. Sfanos KS, Sauvageot J, Fedor HL, Dick JD, De Marzo AM, et al. (2008) A molecular analysis of prokaryotic and viral DNA sequences in prostate tissue from patients with prostate cancer indicates the presence of multiple and diverse microorganisms. Prostate 68: 306-320.
12. Alexeyev O, Bergh J, Marklund I, Thellenberg-Karlsson C, Wiklund F, et al. (2006) Association between the presence of bacterial 16S RNA in prostate specimens taken during transurethral resection of prostate and subsequent risk of prostate cancer (Sweden). Cancer Causes Control 17: 1127-1133.
13. Cohen RJ, Shannon BA, McNeal JE, Shannon T, Garrett KL, (2005) Propionibacterium acnes associated with inflammation in radical prostatectomy specimens: a possible link to cancer evolution? J Urol 173: 1969-1974.
14. Fassi Fehri L, Mak TN, Laube B, Brinkmann V, Ogilvie LA,et al. (2010) Prevalence of Propionibacterium acnes in diseased prostates and its inflammatory and transforming activity on prostate epithelial cells. Int J Med Microbiol.
15. Shannon BA, Cohen RJ, Garrett KL, (2008) The antibody response to Propionibacterium acnes is an independent predictor of serum prostate-specific antigen levels in biopsy-negative men. BJU Int 101: 429-435.
16. Drott J, Alexeyev O, Bergstrom P, Elgh F, Olsson J, (2010) Propionibacterium acnes infection induces upregulation of inflammatory genes and cytokine secretion in prostate epithelial cells. BMC Microbiology 10: 126.
17. Olsson J, Davidsson S, Unemo M, Mölling P, Andersson S-O, et al. (2012) Antibiotic susceptibility in prostate-derived Propionibacterium acnes isolates. APMIS 120: 778-785.
18. Halin S, Hammarsten P, Wikstrom P, Bergh A, (2007) Androgen-insensitive prostate cancer cells transiently respond to castration treatment when growing in an androgen-dependent prostate environment. The Prostate 67: 370-377.
19. McDowell A, Valanne S, Ramage G, Tunney MM, Glenn JV, et al. (2005) Propionibacterium acnes types I and II represent phylogenetically distinct groups. Journal of clinical microbiology 43: 326-334.
20. Goldschmidt P, Ferreira CC, Degorge S, Benallaoua D, Boutboul S, et al. (2009) Rapid detection and quantification of Propionibacteriaceae. Br J Ophthalmol 93: 258-262.
21. Good PI (2005) Permutation, parametric and bootstrap tests of hypotheses. New York: Springer. xix, 315 p. p.
22. Kaplan L, Lee C, Schaeffer AJ, (1983) Effect of castration on experimental bacterial prostatitis in rats. The Prostate 4: 625-630.
23. Boehm BJ, Colopy SA, Jerde TJ, Loftus CJ, Bushman W, (2012) Acute bacterial inflammation of the mouse prostate. The Prostate 72: 307-317.
24. Lomholt HB, Kilian M, (2010) Population genetic analysis of Propionibacterium acnes identifies a subpopulation and epidemic clones associated with acne. PLoS One 5: e12277.
25. de Beer FC, Baltz ML, Munn EA, Feinstein A, Taylor J, et al. (1982) Isolation and characterization of C-reactive protein and serum amyloid P component in the rat. Immunology 45: 55-70.
26. Naslund MJ, Strandberg JD, Coffey DS, (1988) The role of androgens and estrogens in the pathogenesis of experimental nonbacterial prostatitis. The Journal of urology 140: 1049-1053.
27. Sharma OP, Adlercreutz H, Strandberg JD, Zirkin BR, Coffey DS, et al. (1992) Soy of dietary source plays a preventive role against the pathogenesis of prostatitis in rats. The Journal of steroid biochemistry and molecular biology 43: 557-564.
28. Khalili M, Mutton LN, Gurel B, Hicks JL, De Marzo AM,et al. (2010) Loss of Nkx3.1 Expression in Bacterial Prostatitis. A Potential Link Between Inflammation and Neoplasia. Am J Pathol.
29. Elkahwaji JE, Hauke RJ, Brawner CM, (2009) Chronic bacterial inflammation induces prostatic intraepithelial neoplasia in mouse prostate. Br J Cancer 101: 1740-1748.
30. Elkahwaji JE, Ott CJ, Janda LM, Hopkins WJ, (2005) Mouse model for acute bacterial prostatitis in genetically distinct inbred strains. Urology 66: 883-887.
31. Yanamandra K, Alexeyev O, Zamotin V, Srivastava V, Shchukarev A, et al. (2009) Amyloid formation by the pro-inflammatory S100A8/A9 proteins in the ageing prostate. PLoS One 4: e5562.
32. Sfanos KS, Wilson BA, De Marzo AM, Isaacs WB, (2009) Acute inflammatory proteins constitute the organic matrix of prostatic corpora amylacea and calculi in men with prostate cancer. Proceedings of the National Academy of Sciences of the United States of America 106: 3443-3448.