Cell invasion and pyruvate oxidase-derived H 2 O 2 are critical for Streptococcus pneumoniae-mediated cardiomyocyte killing

Infection and Immunity

Volumn 86, Issue 1, 2018, Pages

  Brissac, Terry ^a   Shenoy, Anukul T ^a   Patterson, LaDonna A ^a   Orihuela, Carlos J ^a  

^a University of Alabama at Birmingham   (United States)

Author keywords

Cardiac acute events; Cardiomyocytes; Facultatively intracellular pathogens; Invasive pneumococcal disease; Oxidative stress; Streptococcus pneumoniae

Indexed keywords

BINDING PROTEIN; BROXURIDINE; CHOLINE; CLATHRIN; GENTAMICIN; HYDROGEN PEROXIDE; LAMININ RECEPTOR; NEUTRALIZING ANTIBODY; PHOSPHORYLCHOLINE; PNEUMOLYSIN; PYRUVATE OXIDASE; SECRETORY COMPONENT; THROMBOCYTE ACTIVATING FACTOR RECEPTOR; BACTERIAL PROTEIN; PLY PROTEIN, STREPTOCOCCUS PNEUMONIAE; STREPTOLYSIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; CARDIAC MUSCLE CELL; CELL ADHESION; CELL DEATH; CELL INVASION; CELL KILLING; CELL MEMBRANE; CELL WALL; CONTROLLED STUDY; CYTOPLASM; CYTOTOXICITY; ENDOCYTOSIS; HL-1 CELL LINE; HOST PATHOGEN INTERACTION; IMMUNOFLUORESCENCE; IMMUNOFLUORESCENCE MICROSCOPY; IN VITRO STUDY; MOUSE; NONHUMAN; PNEUMOCOCCAL INFECTION; PRIORITY JOURNAL; STREPTOCOCCUS PNEUMONIAE; TRANSMISSION ELECTRON MICROSCOPY; VASCULAR ENDOTHELIAL CELL; VASCULAR ENDOTHELIUM; ANIMAL; BAGG ALBINO MOUSE; CELL SURVIVAL; DRUG EFFECT; FEMALE; GENE EXPRESSION REGULATION; IMMUNOLOGY; METABOLISM; MICROBIOLOGY;

ANIMALS; BACTERIAL PROTEINS; CELL SURVIVAL; FEMALE; GENE EXPRESSION REGULATION, BACTERIAL; GENE EXPRESSION REGULATION, ENZYMOLOGIC; HYDROGEN PEROXIDE; MICE; MICE, INBRED BALB C; MYOCYTES, CARDIAC; PNEUMOCOCCAL INFECTIONS; PYRUVATE OXIDASE; STREPTOCOCCUS PNEUMONIAE; STREPTOLYSINS;

EID: 85039763247     PISSN: 00199567     EISSN: 10985522     Source Type: Journal    
DOI: 10.1128/IAI.00569-17     Document Type: Article

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