Infiltrated macrophages die of pneumolysin-mediated necroptosis following pneumococcal myocardial invasion

Infection and Immunity

Volumn 84, Issue 5, 2016, Pages 1457-1469

  Gilley, Ryan P ^a   González Juarbe, Norberto ^a,b   Shenoy, Anukul T ^a,b   Reyes, Luis F ^a   Dube, Peter H ^a   Restrepo, Marcos I ^a,c   Orihuela, Carlos J ^a,b  

^a UNIVERSITY OF TEXAS HEALTH SCIENCE CENTER AT SAN ANTONIO   (United States)

^b University of Alabama at Birmingham   (United States)

^c SOUTH TEXAS VETERANS HEALTH CARE SYSTEM   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CD11B ANTIGEN; EOSIN; HEMATOXYLIN; MIXED LINEAGE KINASE; MIXED LINEAGE KINASE DOMAIN LIKE PROTEIN; NECROSTATIN 5; PHOSPHOTRANSFERASE; PNEUMOLYSIN; RECEPTOR INTERACTING PROTEIN 1 KINASE; UNCLASSIFIED DRUG; BACTERIAL PROTEIN; MLKL PROTEIN, MOUSE; PLY PROTEIN, STREPTOCOCCUS PNEUMONIAE; PROTEIN KINASE; STREPTOLYSIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BACTEREMIA; BACTERIAL STRAIN; BACTERIUM ISOLATE; CARDIAC MUSCLE; CARDIAC MUSCLE CELL; CELL DEATH; CELL INFILTRATION; CONTROLLED STUDY; DEGENERATION; DISEASE COURSE; HEART INJURY; IMMUNOCOMPETENT CELL; IMMUNOFLUORESCENCE MICROSCOPY; IN VITRO STUDY; MACROPHAGE; MICROSCOPY; MOUSE; NECROPTOSIS; NEUTROPHIL; NONHUMAN; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; SEROTYPE; STAINING; STREPTOCOCCUS PNEUMONIAE; TISSUE INJURY; ANIMAL; BAGG ALBINO MOUSE; CELL LINE; DISEASE MODEL; DRUG EFFECTS; FEMALE; FLUORESCENCE MICROSCOPY; HUMAN; METABOLISM; MYOCARDITIS; PATHOGENICITY; PATHOLOGY; PHYSIOLOGY; PNEUMOCOCCAL INFECTION;

ANIMALS; BACTEREMIA; BACTERIAL PROTEINS; CELL DEATH; CELL LINE; DISEASE MODELS, ANIMAL; FEMALE; HUMANS; MACROPHAGES; MICE, INBRED BALB C; MICROSCOPY, FLUORESCENCE; MYOCARDITIS; PNEUMOCOCCAL INFECTIONS; PROTEIN KINASES; STREPTOCOCCUS PNEUMONIAE; STREPTOLYSINS;

EID: 84965153045     PISSN: 00199567     EISSN: 10985522     Source Type: Journal    
DOI: 10.1128/IAI.00007-16     Document Type: Article

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