Streptococcus pneumoniae Translocates into the Myocardium and Forms Unique Microlesions That Disrupt Cardiac Function

PLoS Pathogens

Volumn 10, Issue 9, 2014, Pages

  Brown, Armand O ^a   Mann, Beth ^b   Gao, Geli ^b   Hankins, Jane S ^b   Humann, Jessica ^b   Giardina, Jonathan ^b   Faverio, Paola ^c   Restrepo, Marcos I ^a   Halade, Ganesh V ^d   Mortensen, Eric M ^e   Lindsey, Merry L ^f   Hanes, Martha ^g   Happel, Kyle I ^h   Nelson, Steve ^h   Bagby, Gregory J ^h   Lorent, Jose A ⁱ   Cardinal, Pablo ⁱ   Granados, Rosario ⁱ   Esteban, Andres ⁱ   LeSaux, Claude J ^g   Tuomanen, Elaine I ^b   Orihuela, Carlos J ^a   more..

^a University of Texas Health Science Center   (United States)

^b ST JUDE CHILDREN S RESEARCH HOSPITAL   (United States)

^c UNIVERSITY OF MILANO BICOCCA   (Italy)

^d University of Alabama at Birmingham and Birmingham Veterans Affairs Medical Center   (United States)

^e UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

^f UNIVERSITY OF MISSISSIPPI SCHOOL OF MEDICINE   (United States)

^g UNIVERSITY OF TEXAS HEALTH SCIENCE CENTER AT SAN ANTONIO   (United States)

^h LOUISIANA STATE UNIVERSITY SCHOOL OF MEDICINE   (United States)

ⁱ HOSPITAL UNIVERSITARIO DE GETAFE   (Spain)

Author keywords

[No Author keywords available]

Indexed keywords

PNEUMOLYSIN; ADHESIN; BACTERIAL PROTEIN; CBPA PROTEIN, BACTERIA; FIBRINOGEN RECEPTOR; G PROTEIN COUPLED RECEPTOR; INTERLEUKIN 1BETA; LAMININ RECEPTOR; PLY PROTEIN, STREPTOCOCCUS PNEUMONIAE; STREPTOLYSIN; THROMBOCYTE ACTIVATING FACTOR RECEPTOR;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BACTERIAL LOAD; CELL INFILTRATION; CONTROLLED STUDY; ELECTROPHYSIOLOGY; ENZYME LINKED IMMUNOSORBENT ASSAY; FLUORESCENCE MICROSCOPY; HEART FUNCTION; HEART INJURY; HEART MUSCLE; HISTOLOGY; IMMUNOCOMPETENT CELL; IMMUNOHISTOCHEMISTRY; MALE; MICROSCOPY; MOUSE; NICK END LABELING; NONHUMAN; PROTEIN EXPRESSION; REGRESSION ANALYSIS; STREPTOCOCCUS PNEUMONIAE; TRANSMISSION ELECTRON MICROSCOPY; ANIMAL; BAGG ALBINO MOUSE; C57BL MOUSE; FEMALE; IMMUNIZATION; IMMUNOLOGY; MACACA; METABOLISM; MICROBIOLOGY; PATHOGENICITY; PATHOLOGY; PNEUMOCOCCAL INFECTION;

STREPTOCOCCUS PNEUMONIAE;

ADHESINS, BACTERIAL; ANIMALS; BACTERIAL PROTEINS; FEMALE; IMMUNIZATION; INTERLEUKIN-1BETA; MACACA; MALE; MICE; MICE, INBRED BALB C; MICE, INBRED C57BL; MYOCARDIUM; PLATELET MEMBRANE GLYCOPROTEINS; PNEUMOCOCCAL INFECTIONS; RECEPTORS, G-PROTEIN-COUPLED; RECEPTORS, LAMININ; STREPTOCOCCUS PNEUMONIAE; STREPTOLYSINS;

EID: 84907572308     PISSN: 15537366     EISSN: 15537374     Source Type: Journal    
DOI: 10.1371/journal.ppat.1004383     Document Type: Article

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