-
1
-
-
84964969174
-
Phase 1 Trials of rVSV Ebola Vaccine in Africa and Europe
-
Agnandji ST, Huttner A, Zinser ME, Njuguna P, Dahlke C, Fernandes JF, Yerly S, Dayer JA, Kraehling V, Kasonta R, Adegnika AA, Altfeld M, Auderset F, Bache EB, Biedenkopf N, Borregaard S, Brosnahan JS, Burrow R, Combescure C, Desmeules J, Eickmann M, Fehling SK, Finckh A, Goncalves AR, Grobusch MP, Hooper J, Jambrecina A, Kabwende AL, Kaya G, Kimani D, Lell B, Lemaitre B, Lohse AW, Massinga-Loembe M, Matthey A, Mordmuller B, Nolting A, Ogwang C, Ramharter M, Schmidt-Chanasit J, Schmiedel S, Silvera P, Stahl FR, Staines HM, Strecker T, Stubbe HC, Tsofa B, Zaki S, Fast P, Moorthy V, Kaiser L, Krishna S, Becker S, Kieny MP, Bejon P, Kremsner PG, Addo MM, Siegrist CA (2016) Phase 1 Trials of rVSV Ebola Vaccine in Africa and Europe. New Engl J Med 374(17):1647–1660. doi:10.1056/NEJMoa1502924.
-
(2016)
New Engl J Med
, vol.374
, Issue.17
, pp. 1647-1660
-
-
Agnandji, S.T.1
Huttner, A.2
Zinser, M.E.3
Njuguna, P.4
Dahlke, C.5
Fernandes, J.F.6
Yerly, S.7
Dayer, J.A.8
Kraehling, V.9
Kasonta, R.10
Adegnika, A.A.11
Altfeld, M.12
Auderset, F.13
Bache, E.B.14
Biedenkopf, N.15
Borregaard, S.16
Brosnahan, J.S.17
Burrow, R.18
Combescure, C.19
Desmeules, J.20
Eickmann, M.21
Fehling, S.K.22
Finckh, A.23
Goncalves, A.R.24
Grobusch, M.P.25
Hooper, J.26
Jambrecina, A.27
Kabwende, A.L.28
Kaya, G.29
Kimani, D.30
Lell, B.31
Lemaitre, B.32
Lohse, A.W.33
Massinga-Loembe, M.34
Matthey, A.35
Mordmuller, B.36
Nolting, A.37
Ogwang, C.38
Ramharter, M.39
Schmidt-Chanasit, J.40
Schmiedel, S.41
Silvera, P.42
Stahl, F.R.43
Staines, H.M.44
Strecker, T.45
Stubbe, H.C.46
Tsofa, B.47
Zaki, S.48
Fast, P.49
Moorthy, V.50
Kaiser, L.51
Krishna, S.52
Becker, S.53
Kieny, M.P.54
Bejon, P.55
Kremsner, P.G.56
Addo, M.M.57
Siegrist, C.A.58
more..
-
2
-
-
84965181522
-
Chasing Ebola through the Endosomal Labyrinth
-
Aman MJ (2016) Chasing Ebola through the Endosomal Labyrinth. MBio 7(2), e00346. doi:10.1128/mBio.00346-16.
-
(2016)
Mbio
, vol.7
, Issue.2
-
-
Aman, M.J.1
-
3
-
-
84994408776
-
Clinical and Virological Characteristics of Ebola Virus Disease Patients Treated With Favipiravir (T-705)-Sierra Leone 2014
-
Bai CQ, Mu JS, Kargbo D, Song YB, Niu WK, Nie WM, Kanu A, Liu WW, Wang YP, Dafae F, Yan T, Hu Y, Deng YQ, Lu HJ, Yang F, Zhang XG, Sun Y, Cao YX, Su HX, Sun Y, Liu WS, Wang CY, Qian J, Liu L, Wang H, Tong YG, Liu ZY, Chen YS, Wang HQ, Kargbo B, Gao GF, Jiang JF (2016) Clinical and Virological Characteristics of Ebola Virus Disease Patients Treated With Favipiravir (T-705)-Sierra Leone 2014. Clin Infect Dis: Official publication Infect Dis Soc Am 63(10):1288–1294. doi:10.1093/cid/ciw571.
-
(2016)
Clin Infect Dis: Official Publication Infect Dis Soc Am
, vol.63
, Issue.10
, pp. 1288-1294
-
-
Bai, C.Q.1
Mu, J.S.2
Kargbo, D.3
Song, Y.B.4
Niu, W.K.5
Nie, W.M.6
Kanu, A.7
Liu, W.W.8
Wang, Y.P.9
Dafae, F.10
Yan, T.11
Hu, Y.12
Deng, Y.Q.13
Lu, H.J.14
Yang, F.15
Zhang, X.G.16
Sun, Y.17
Cao, Y.X.18
Su, H.X.19
Sun, Y.20
Liu, W.S.21
Wang, C.Y.22
Qian, J.23
Liu, L.24
Wang, H.25
Tong, Y.G.26
Liu, Z.Y.27
Chen, Y.S.28
Wang, H.Q.29
Kargbo, B.30
Gao, G.F.31
Jiang, J.F.32
more..
-
4
-
-
84943228616
-
Novel Small Molecule Entry Inhibitors of Ebola Virus
-
Basu A, Mills DM, Mitchell D, Ndungo E, Williams JD, Herbert AS, Dye JM, Moir DT, Chandran K, Patterson JL, Rong L, Bowlin TL (2015) Novel Small Molecule Entry Inhibitors of Ebola Virus. J Infect Dis 212(Suppl 2):425–434. doi:10.1093/infdis/jiv223.
-
(2015)
J Infect Dis
, vol.212
, pp. 425-434
-
-
Basu, A.1
Mills, D.M.2
Mitchell, D.3
Ndungo, E.4
Williams, J.D.5
Herbert, A.S.6
Dye, J.M.7
Moir, D.T.8
Chandran, K.9
Patterson, J.L.10
Rong, L.11
Bowlin, T.L.12
-
5
-
-
0029440828
-
Development and study of the properties of immunoglobulin against Ebola fever
-
Borisevich IV, Mikhailov VV, Krasnianskii VP, Gradoboev VN, Lebedinskaia EV, Potryvaeva NV, Timan’kova GD (1995) Development and study of the properties of immunoglobulin against Ebola fever. Vopr Virusol 40(6):270–273.
-
(1995)
Vopr Virusol
, vol.40
, Issue.6
, pp. 270-273
-
-
Borisevich, I.V.1
Mikhailov, V.V.2
Krasnianskii, V.P.3
Gradoboev, V.N.4
Lebedinskaia, E.V.5
Potryvaeva, N.V.6
Timan’Kova, G.D.7
-
6
-
-
85044702480
-
Development of the immunoenzyme test-system for detection of Ebola virus antigen
-
Borisevich IV, Mikhailov VV, Potryvaeva NV, Malinkin IuN, Kirillov AP, Krasnianskii VP, Markov VI, Makhlai AA, Lebedinskaia EV (1996) Development of the immunoenzyme test-system for detection of Ebola virus antigen. Vopr Virusol 41(5):232–234.
-
(1996)
Vopr Virusol
, vol.41
, Issue.5
, pp. 232-234
-
-
Borisevich, I.V.1
Mikhailov, V.V.2
Potryvaeva, N.V.3
Malinkin, I.4
Kirillov, A.P.5
Krasnianskii, V.P.6
Markov, V.I.7
Makhlai, A.A.8
Lebedinskaia, E.V.9
-
7
-
-
40249117529
-
Design of equine serum-based Marburg virus immunoglobulin
-
Borisevich IV, Potryvaeva NV, Mel’nikov SA, Evseev AA, Krasnianskii VP, Maksimov VA (2008) Design of equine serum-based Marburg virus immunoglobulin. Vopr Virusol 53(1):39–41.
-
(2008)
Vopr Virusol
, vol.53
, Issue.1
, pp. 39-41
-
-
Borisevich, I.V.1
Potryvaeva, N.V.2
Mel’Nikov, S.A.3
Evseev, A.A.4
Krasnianskii, V.P.5
Maksimov, V.A.6
-
8
-
-
84963997546
-
Risk factors for transmission of Ebola or Marburg virus disease: A systematic review and meta-analysis
-
Brainard J, Hooper L, Pond K, Edmunds K, Hunter PR (2016a) Risk factors for transmission of Ebola or Marburg virus disease: a systematic review and meta-analysis. Int J Epidemiol 45(1):102–116. doi:10.1093/ije/dyv307.
-
(2016)
Int J Epidemiol
, vol.45
, Issue.1
, pp. 102-116
-
-
Brainard, J.1
Hooper, L.2
Pond, K.3
Edmunds, K.4
Hunter, P.R.5
-
9
-
-
84959257913
-
Presence and persistence of ebola or marburg virus in patients and survivors: A rapid systematic review
-
Brainard J, Pond K, Hooper L, Edmunds K, Hunter P (2016b) Presence and persistence of ebola or marburg virus in patients and survivors: a rapid systematic review. PLoS Neglected Tropical Dis 10(2):e0004475. doi:10.1371/journal.pntd.0004475.
-
(2016)
Plos Neglected Tropical Dis
, vol.10
, Issue.2
-
-
Brainard, J.1
Pond, K.2
Hooper, L.3
Edmunds, K.4
Hunter, P.5
-
10
-
-
55249105224
-
Gabon centre refocuses on emerging diseases
-
Butler D (2008) Gabon centre refocuses on emerging diseases. Nature 455(7217), 1156–1157. doi:10.1038/4551156b.
-
(2008)
Nature
, vol.455
, Issue.7217
, pp. 1156-1157
-
-
Butler, D.1
-
11
-
-
84987956532
-
Antiviral therapeutics for the treatment of Ebola virus infection
-
Cardile AP, Downey LG, Wiseman PD, Warren TK, Bavari S (2016a) Antiviral therapeutics for the treatment of Ebola virus infection. Curr Opin Pharmacol 30:138–143. doi:10.1016/j.coph.2016.08.016.
-
(2016)
Curr Opin Pharmacol
, vol.30
, pp. 138-143
-
-
Cardile, A.P.1
Downey, L.G.2
Wiseman, P.D.3
Warren, T.K.4
Bavari, S.5
-
14
-
-
84940997614
-
Inhibition of Ebola and Marburg virus entry by G Protein-coupled receptor Antagonists
-
Cheng H, Lear-Rooney CM, Johansen L, Varhegyi E, Chen ZW, Olinger GG, Rong L (2015) Inhibition of Ebola and Marburg virus entry by G Protein-coupled receptor Antagonists. J Virol 89(19):9932–9938. doi:10.1128/jvi.01337-15.
-
(2015)
J Virol
, vol.89
, Issue.19
, pp. 9932-9938
-
-
Cheng, H.1
Lear-Rooney, C.M.2
Johansen, L.3
Varhegyi, E.4
Chen, Z.W.5
Olinger, G.G.6
Rong, L.7
-
15
-
-
84915804508
-
Ebola virus disease in West Africa–clinical manifestations and management
-
Chertow DS, Kleine C, Edwards JK, Scaini R, Giuliani R, Sprecher A (2014) Ebola virus disease in West Africa–clinical manifestations and management. New Engl J Med 371(22):2054–2057. doi:10.1056/NEJMp1413084.
-
(2014)
New Engl J Med
, vol.371
, Issue.22
, pp. 2054-2057
-
-
Chertow, D.S.1
Kleine, C.2
Edwards, J.K.3
Scaini, R.4
Giuliani, R.5
Sprecher, A.6
-
16
-
-
84952927765
-
Infectious Disease. As Ebola epidemic draws to a close, a thin scientific harvest
-
Cohen J, Enserink M (2016) Infectious Disease. As Ebola epidemic draws to a close, a thin scientific harvest. Science 351(6268):12–13. doi:10.1126/science.351.6268.12.
-
(2016)
Science
, vol.351
, Issue.6268
, pp. 12-13
-
-
Cohen, J.1
Enserink, M.2
-
17
-
-
84959359636
-
Protective monotherapy against lethal Ebola virus infection by a potently neutralizing antibody
-
Corti D, Misasi J, Mulangu S, Stanley DA, Kanekiyo M, Wollen S, Ploquin A, Doria-Rose NA, Staupe RP, Bailey M, Shi W, Choe M, Marcus H, Thompson EA, Cagigi A, Silacci C, Fernandez-Rodriguez B, Perez L, Sallusto F, Vanzetta F, Agatic G, Cameroni E, Kisalu N, Gordon I, Ledgerwood JE, Mascola JR, Graham BS, Muyembe-Tamfun JJ, Trefry JC, Lanzavecchia A, Sullivan NJ (2016) Protective monotherapy against lethal Ebola virus infection by a potently neutralizing antibody. Science 351(6279):1339–1342. doi:10.1126/science.aad5224.
-
(2016)
Science
, vol.351
, Issue.6279
, pp. 1339-1342
-
-
Corti, D.1
Misasi, J.2
Mulangu, S.3
Stanley, D.A.4
Kanekiyo, M.5
Wollen, S.6
Ploquin, A.7
Doria-Rose, N.A.8
Staupe, R.P.9
Bailey, M.10
Shi, W.11
Choe, M.12
Marcus, H.13
Thompson, E.A.14
Cagigi, A.15
Silacci, C.16
Fernandez-Rodriguez, B.17
Perez, L.18
Sallusto, F.19
Vanzetta, F.20
Agatic, G.21
Cameroni, E.22
Kisalu, N.23
Gordon, I.24
Ledgerwood, J.E.25
Mascola, J.R.26
Graham, B.S.27
Muyembe-Tamfun, J.J.28
Trefry, J.C.29
Lanzavecchia, A.30
Sullivan, N.J.31
more..
-
18
-
-
80052868218
-
Small molecule inhibitors reveal Niemann-Pick C1 is essential for Ebola virus infection
-
Cote M, Misasi J, Ren T, Bruchez A, Lee K, Filone CM, Hensley L, Li Q, Ory D, Chandran K, Cunningham J (2011) Small molecule inhibitors reveal Niemann-Pick C1 is essential for Ebola virus infection. Nature 477(7364):344–348. doi:10.1038/nature10380.
-
(2011)
Nature
, vol.477
, Issue.7364
, pp. 344-348
-
-
Cote, M.1
Misasi, J.2
Ren, T.3
Bruchez, A.4
Lee, K.5
Filone, C.M.6
Hensley, L.7
Li, Q.8
Ory, D.9
Chandran, K.10
Cunningham, J.11
-
19
-
-
84871894016
-
Catheterized guinea pigs infected with Ebola Zaire virus allows safer sequential sampling to determine the pharmacokinetic profile of a phosphatidylserine-targeting monoclonal antibody
-
Dowall S, Taylor I, Yeates P, Smith L, Rule A, Easterbrook L, Bruce C, Cook N, Corbin-Lickfett K, Empig C, Schlunegger K, Graham V, Dennis M, Hewson R (2013) Catheterized guinea pigs infected with Ebola Zaire virus allows safer sequential sampling to determine the pharmacokinetic profile of a phosphatidylserine-targeting monoclonal antibody. Antiviral Res 97(2):108–111. doi:10.1016/j.antiviral.2012.11.003.
-
(2013)
Antiviral Res
, vol.97
, Issue.2
, pp. 108-111
-
-
Dowall, S.1
Taylor, I.2
Yeates, P.3
Smith, L.4
Rule, A.5
Easterbrook, L.6
Bruce, C.7
Cook, N.8
Corbin-Lickfett, K.9
Empig, C.10
Schlunegger, K.11
Graham, V.12
Dennis, M.13
Hewson, R.14
-
20
-
-
84979929572
-
Post-exposure treatment of Ebola virus disease in guinea pigs using EBOTAb, an ovine antibody-based therapeutic
-
Dowall SD, Bosworth A, Rayner E, Taylor I, Landon J, Cameron I, Coxon R, Al Abdulla I, Graham VA, Hall G, Kobinger G, Hewson R, Carroll MW (2016) Post-exposure treatment of Ebola virus disease in guinea pigs using EBOTAb, an ovine antibody-based therapeutic. Sci Rep 6:30497. doi:10.1038/srep30497.
-
(2016)
Sci Rep
, vol.6
-
-
Dowall, S.D.1
Bosworth, A.2
Rayner, E.3
Taylor, I.4
Landon, J.5
Cameron, I.6
Coxon, R.7
Al Abdulla, I.8
Graham, V.A.9
Hall, G.10
Kobinger, G.11
Hewson, R.12
Carroll, M.W.13
-
21
-
-
84925307941
-
Effective binding of a phosphatidylserine-targeting antibody to Ebola virus infected cells and purified virions
-
Dowall SD, Graham VA, Corbin-Lickfett K, Empig C, Schlunegger K, Bruce CB, Easterbrook L, Hewson R (2015) Effective binding of a phosphatidylserine-targeting antibody to Ebola virus infected cells and purified virions. J Immunol Res 2015:347903. doi:10.1155/2015/347903.
-
(2015)
J Immunol Res
, vol.2015
-
-
Dowall, S.D.1
Graham, V.A.2
Corbin-Lickfett, K.3
Empig, C.4
Schlunegger, K.5
Bruce, C.B.6
Easterbrook, L.7
Hewson, R.8
-
22
-
-
84990973699
-
Experimental treatment of ebola virus disease with Brincidofovir
-
Dunning J, Kennedy SB, Antierens A, Whitehead J, Ciglenecki I, Carson G, Kanapathipillai R, Castle L, Howell-Jones R, Pardinaz-Solis R, Grove J, Scott J, Lang T, Olliaro P, Horby PW (2016a) Experimental treatment of ebola virus disease with Brincidofovir. PLoS ONE 11(9):e0162199. doi:10.1371/journal.pone.0162199.
-
(2016)
Plos ONE
, vol.11
, Issue.9
-
-
Dunning, J.1
Kennedy, S.B.2
Antierens, A.3
Whitehead, J.4
Ciglenecki, I.5
Carson, G.6
Kanapathipillai, R.7
Castle, L.8
Howell-Jones, R.9
Pardinaz-Solis, R.10
Grove, J.11
Scott, J.12
Lang, T.13
Olliaro, P.14
Horby, P.W.15
-
23
-
-
84964720831
-
Experimental treatment of Ebola virus disease with TKM-130803: A Single-Arm Phase 2 Clinical Trial
-
Dunning J, Sahr F, Rojek A, Gannon F, Carson G, Idriss B, Massaquoi T, Gandi R, Joseph S, Osman HK, Brooks TJ, Simpson AJ, Goodfellow I, Thorne L, Arias A, Merson L, Castle L, Howell-Jones R, Pardinaz-Solis R, Hope-Gill B, Ferri M, Grove J, Kowalski M, Stepniewska K, Lang T, Whitehead J, Olliaro P, Samai M, Horby PW (2016b) Experimental treatment of Ebola virus disease with TKM-130803: a Single-Arm Phase 2 Clinical Trial. PLoS Med 13(4):e1001997. doi:10.1371/journal.pmed.1001997.
-
(2016)
Plos Med
, vol.13
, Issue.4
-
-
Dunning, J.1
Sahr, F.2
Rojek, A.3
Gannon, F.4
Carson, G.5
Idriss, B.6
Massaquoi, T.7
Gandi, R.8
Joseph, S.9
Osman, H.K.10
Brooks, T.J.11
Simpson, A.J.12
Goodfellow, I.13
Thorne, L.14
Arias, A.15
Merson, L.16
Castle, L.17
Howell-Jones, R.18
Pardinaz-Solis, R.19
Hope-Gill, B.20
Ferri, M.21
Grove, J.22
Kowalski, M.23
Stepniewska, K.24
Lang, T.25
Whitehead, J.26
Olliaro, P.27
Samai, M.28
Horby, P.W.29
more..
-
24
-
-
84859462127
-
Postexposure antibody prophylaxis protects nonhuman primates from filovirus disease
-
Dye JM, Herbert AS, Kuehne AI, Barth JF, Muhammad MA, Zak SE, Ortiz RA, Prugar LI, Pratt WD (2012) Postexposure antibody prophylaxis protects nonhuman primates from filovirus disease. Proc Natl Acad Sci USA 109(13):5034–5039. doi:10.1073/pnas.1200409109.
-
(2012)
Proc Natl Acad Sci USA
, vol.109
, Issue.13
, pp. 5034-5039
-
-
Dye, J.M.1
Herbert, A.S.2
Kuehne, A.I.3
Barth, J.F.4
Muhammad, M.A.5
Zak, S.E.6
Ortiz, R.A.7
Prugar, L.I.8
Pratt, W.D.9
-
25
-
-
84964658344
-
Production of Potent Fully Human Polyclonal Antibodies against Ebola Zaire Virus in Transchromosomal Cattle
-
Dye JM, Wu H, Hooper JW, Khurana S, Kuehne AI, Coyle EM, Ortiz RA, Fuentes S, Herbert AS, Golding H, Bakken RA, Brannan JM, Kwilas SA, Sullivan EJ, Luke TC, Smith G, Glenn G, Li W, Ye L, Yang C, Compans RW, Tripp RA, Jiao JA (2016) Production of Potent Fully Human Polyclonal Antibodies against Ebola Zaire Virus in Transchromosomal Cattle. Sci Rep 6:24897. doi:10.1038/srep24897.
-
(2016)
Sci Rep
, vol.6
-
-
Dye, J.M.1
Wu, H.2
Hooper, J.W.3
Khurana, S.4
Kuehne, A.I.5
Coyle, E.M.6
Ortiz, R.A.7
Fuentes, S.8
Herbert, A.S.9
Golding, H.10
Bakken, R.A.11
Brannan, J.M.12
Kwilas, S.A.13
Sullivan, E.J.14
Luke, T.C.15
Smith, G.16
Glenn, G.17
Li, W.18
Ye, L.19
Yang, C.20
Compans, R.W.21
Tripp, R.A.22
Jiao, J.A.23
more..
-
26
-
-
0017737552
-
A case of Ebola virus infection
-
Emond RT, Evans B, Bowen ET, Lloyd G (1977) A case of Ebola virus infection. BMJ 2(6086):541–544.
-
(1977)
BMJ
, vol.2
, Issue.6086
, pp. 541-544
-
-
Emond, R.T.1
Evans, B.2
Bowen, E.T.3
Lloyd, G.4
-
27
-
-
0021187216
-
Importance of dose of neutralising antibodies in treatment of Argentine haemorrhagic fever with immune plasma
-
Enria D, Fernandez N, Briggiler A, Levis S, Maiztegui J (1984) Importance of dose of neutralising antibodies in treatment of Argentine haemorrhagic fever with immune plasma. The Lancet 324(8397):255–256.
-
(1984)
The Lancet
, vol.324
, Issue.8397
, pp. 255-256
-
-
Enria, D.1
Fernandez, N.2
Briggiler, A.3
Levis, S.4
Maiztegui, J.5
-
28
-
-
84974717508
-
Filoviridae: Marburg and Ebola viruses
-
Knipe DM, Howley PM, 6th edn. Lippincott Williams and Wilkins, Philadelphia
-
Feldmann HSa, Geisbert TW (2013) Filoviridae: Marburg and Ebola viruses. In: Knipe DM, Howley PM (eds) Fields Firology, 6th edn. Lippincott Williams and Wilkins, Philadelphia, pp 923–956.
-
(2013)
Fields Firology
, pp. 923-956
-
-
Hsa, F.1
Geisbert, T.W.2
-
29
-
-
84875451700
-
Identification of a broad-spectrum inhibitor of viral RNA synthesis: Validation of a prototype virus-based approach
-
Filone CM, Hodges EN, Honeyman B, Bushkin GG, Boyd K, Platt A, Ni F, Strom K, Hensley L, Snyder JK, Connor JH (2013) Identification of a broad-spectrum inhibitor of viral RNA synthesis: validation of a prototype virus-based approach. Chem Biol 20(3):424–433. doi:10.1016/j.chembiol.2013.02.011.
-
(2013)
Chem Biol
, vol.20
, Issue.3
, pp. 424-433
-
-
Filone, C.M.1
Hodges, E.N.2
Honeyman, B.3
Bushkin, G.G.4
Boyd, K.5
Platt, A.6
Ni, F.7
Strom, K.8
Hensley, L.9
Snyder, J.K.10
Connor, J.H.11
-
30
-
-
84955583640
-
Protective mAbs and Cross-Reactive mAbs Raised by Immunization with Engineered Marburg Virus GPs
-
Fusco ML, Hashiguchi T, Cassan R, Biggins JE, Murin CD, Warfield KL, Li S, Holtsberg FW, Shulenin S, Vu H, Olinger GG, Kim DH, Whaley KJ, Zeitlin L, Ward AB, Nykiforuk C, Aman MJ, Berry JD, Saphire EO (2015) Protective mAbs and Cross-Reactive mAbs Raised by Immunization with Engineered Marburg Virus GPs. PLoS Pathog 11(6):e1005016. doi:10.1371/journal.ppat.1005016.
-
(2015)
Plos Pathog
, vol.11
, Issue.6
-
-
Fusco, M.L.1
Hashiguchi, T.2
Cassan, R.3
Biggins, J.E.4
Murin, C.D.5
Warfield, K.L.6
Li, S.7
Holtsberg, F.W.8
Shulenin, S.9
Vu, H.10
Olinger, G.G.11
Kim, D.H.12
Whaley, K.J.13
Zeitlin, L.14
Ward, A.B.15
Nykiforuk, C.16
Aman, M.J.17
Berry, J.D.18
Saphire, E.O.19
-
31
-
-
10744222633
-
Treatment of Ebola virus infection with a recombinant inhibitor of factor VIIa/tissue factor: A study in rhesus monkeys
-
Geisbert TW, Hensley LE, Jahrling PB, Larsen T, Geisbert JB, Paragas J, Young HA, Fredeking TM, Rote WE, Vlasuk GP (2003a) Treatment of Ebola virus infection with a recombinant inhibitor of factor VIIa/tissue factor: a study in rhesus monkeys. Lancet 362(9400):1953–1958. doi:10.1016/s0140-6736(03)15012-x.
-
(2003)
Lancet
, vol.362
, Issue.9400
, pp. 1953-1958
-
-
Geisbert, T.W.1
Hensley, L.E.2
Jahrling, P.B.3
Larsen, T.4
Geisbert, J.B.5
Paragas, J.6
Young, H.A.7
Fredeking, T.M.8
Rote, W.E.9
Vlasuk, G.P.10
-
32
-
-
33645720317
-
Postexposure protection of guinea pigs against a lethal ebola virus challenge is conferred by RNA interference
-
Geisbert TW, Hensley LE, Kagan E, Yu EZ, Geisbert JB, Daddario-DiCaprio K, Fritz EA, Jahrling PB, McClintock K, Phelps JR, Lee AC, Judge A, Jeffs LB, MacLachlan I (2006) Postexposure protection of guinea pigs against a lethal ebola virus challenge is conferred by RNA interference. J Infect Dis 193(12):1650–1657. doi:10.1086/504267.
-
(2006)
J Infect Dis
, vol.193
, Issue.12
, pp. 1650-1657
-
-
Geisbert, T.W.1
Hensley, L.E.2
Kagan, E.3
Yu, E.Z.4
Geisbert, J.B.5
Daddario-Dicaprio, K.6
Fritz, E.A.7
Jahrling, P.B.8
McClintock, K.9
Phelps, J.R.10
Lee, A.C.11
Judge, A.12
Jeffs, L.B.13
Maclachlan, I.14
-
33
-
-
77952680862
-
Postexposure protection of non-human primates against a lethal Ebola virus challenge with RNA interference: a proof-of-concept study
-
Geisbert TW, Lee AC, Robbins M, Geisbert JB, Honko AN, Sood V, Johnson JC, de Jong S, Tavakoli I, Judge A, Hensley LE, Maclachlan I (2010) Postexposure protection of non-human primates against a lethal Ebola virus challenge with RNA interference: a proof-of-concept study. Lancet 375(9729):1896–1905. doi:10.1016/s0140-6736(10)60357-1.
-
(2010)
Lancet
, vol.375
, Issue.9729
, pp. 1896-1905
-
-
Geisbert, T.W.1
Lee, A.C.2
Robbins, M.3
Geisbert, J.B.4
Honko, A.N.5
Sood, V.6
Johnson, J.C.7
De Jong, S.8
Tavakoli, I.9
Judge, A.10
Hensley, L.E.11
Maclachlan, I.12
-
34
-
-
0348053693
-
Mechanisms underlying coagulation abnormalities in ebola hemorrhagic fever: Overexpression of tissue factor in primate monocytes/macrophages is a key event
-
Geisbert TW, Young HA, Jahrling PB, Davis KJ, Kagan E, Hensley LE (2003b) Mechanisms underlying coagulation abnormalities in ebola hemorrhagic fever: overexpression of tissue factor in primate monocytes/macrophages is a key event. J Infect Dis 188(11):1618–1629. doi:10.1086/379724.
-
(2003)
J Infect Dis
, vol.188
, Issue.11
, pp. 1618-1629
-
-
Geisbert, T.W.1
Young, H.A.2
Jahrling, P.B.3
Davis, K.J.4
Kagan, E.5
Hensley, L.E.6
-
35
-
-
84971617618
-
Docetaxel combined With Bavituximab in previously treated, advanced Nonsquamous non-small-cell lung Cancer
-
Gerber DE, Spigel DR, Giorgadze D, Shtivelband M, Ponomarova OV, Shan JS, Menander KB, Belani CP (2016) Docetaxel combined With Bavituximab in previously treated, advanced Nonsquamous non-small-cell lung Cancer. Clin Lung Cancer 17(3):169–176. doi:10.1016/j.cllc.2016.02.003.
-
(2016)
Clin Lung Cancer
, vol.17
, Issue.3
, pp. 169-176
-
-
Gerber, D.E.1
Spigel, D.R.2
Giorgadze, D.3
Shtivelband, M.4
Ponomarova, O.V.5
Shan, J.S.6
Menander, K.B.7
Belani, C.P.8
-
36
-
-
84938943006
-
Improving attrition rates in Ebola virus drug discovery
-
Glisic S, Paessler S, Veljkovic N, Perovic VR, Prljic J, Veljkovic V (2015) Improving attrition rates in Ebola virus drug discovery. Expert Opin Drug Discov 10(9), 1025–1032. doi:10.1517/17460441.2015.1062872.
-
(2015)
Expert Opin Drug Discov
, vol.10
, Issue.9
, pp. 1025-1032
-
-
Glisic, S.1
Paessler, S.2
Veljkovic, N.3
Perovic, V.R.4
Prljic, J.5
Veljkovic, V.6
-
37
-
-
84991259720
-
A randomized, controlled trial of ZMapp for Ebola virus infection
-
Group PIW, Multi-National PIIST (2016) A randomized, controlled trial of ZMapp for Ebola virus infection. New Engl J Med 375(15):1448–1456. doi:10.1056/NEJMoa1604330.
-
(2016)
New Engl J Med
, vol.375
, Issue.15
, pp. 1448-1456
-
-
-
38
-
-
84942279500
-
Addressing therapeutic options for ebola virus infection in current and future outbreaks
-
Haque A, Hober D, Blondiaux J (2015) Addressing therapeutic options for ebola virus infection in current and future outbreaks. Antimicrob Agents Chemot 59(10), 5892-5902. doi:10.1128/Aac.01105-15.
-
(2015)
Antimicrob Agents Chemot
, vol.59
, Issue.10
, pp. 5892-5902
-
-
Haque, A.1
Hober, D.2
Blondiaux, J.3
-
39
-
-
38449092257
-
Recombinant human activated protein C for the postexposure treatment of Ebola hemorrhagic fever
-
Hensley LE, Stevens EL, Yan SB, Geisbert JB, Macias WL, Larsen T, Daddario-DiCaprio KM, Cassell GH, Jahrling PB, Geisbert TW (2007) Recombinant human activated protein C for the postexposure treatment of Ebola hemorrhagic fever. J Infect Dis 196(Suppl 2):390–399. doi:10.1086/520598.
-
(2007)
J Infect Dis
, vol.196
, pp. 390-399
-
-
Hensley, L.E.1
Stevens, E.L.2
Yan, S.B.3
Geisbert, J.B.4
Macias, W.L.5
Larsen, T.6
Daddario-Dicaprio, K.M.7
Cassell, G.H.8
Jahrling, P.B.9
Geisbert, T.W.10
-
40
-
-
84954162282
-
The emergence of antibody therapies for Ebola
-
Hiatt A, Pauly M, Whaley K, Qiu X, Kobinger G, Zeitlin L (2015) The emergence of antibody therapies for Ebola. Hum Antibodies 23(3–4), 49–56. doi:10.3233/HAB-150284.
-
(2015)
Hum Antibodies
, vol.23
, Issue.3-4
, pp. 49-56
-
-
Hiatt, A.1
Pauly, M.2
Whaley, K.3
Qiu, X.4
Kobinger, G.5
Zeitlin, L.6
-
41
-
-
84888069100
-
The cytoprotective enzyme heme oxygenase-1 suppresses Ebola virus replication
-
Hill-Batorski L, Halfmann P, Neumann G, Kawaoka Y (2013) The cytoprotective enzyme heme oxygenase-1 suppresses Ebola virus replication. J Virol 87(24):13795–13802. doi:10.1128/jvi.02422-13.
-
(2013)
J Virol
, vol.87
, Issue.24
, pp. 13795-13802
-
-
Hill-Batorski, L.1
Halfmann, P.2
Neumann, G.3
Kawaoka, Y.4
-
42
-
-
84953862148
-
Pan-ebolavirus and Pan-filovirus Mouse Monoclonal Antibodies: Protection against Ebola and Sudan Viruses
-
Holtsberg FW, Shulenin S, Vu H, Howell KA, Patel SJ, Gunn B, Karim M, Lai JR, Frei JC, Nyakatura EK, Zeitlin L, Douglas R, Fusco ML, Froude JW, Saphire EO, Herbert AS, Wirchnianski AS, Lear-Rooney CM, Alter G, Dye JM, Glass PJ, Warfield KL, Aman MJ (2015) Pan-ebolavirus and Pan-filovirus Mouse Monoclonal Antibodies: Protection against Ebola and Sudan Viruses. J Virol 90(1):266–278. doi:10.1128/JVI.02171-15.
-
(2015)
J Virol
, vol.90
, Issue.1
, pp. 266-278
-
-
Holtsberg, F.W.1
Shulenin, S.2
Vu, H.3
Howell, K.A.4
Patel, S.J.5
Gunn, B.6
Karim, M.7
Lai, J.R.8
Frei, J.C.9
Nyakatura, E.K.10
Zeitlin, L.11
Douglas, R.12
Fusco, M.L.13
Froude, J.W.14
Saphire, E.O.15
Herbert, A.S.16
Wirchnianski, A.S.17
Lear-Rooney, C.M.18
Alter, G.19
Dye, J.M.20
Glass, P.J.21
Warfield, K.L.22
Aman, M.J.23
more..
-
43
-
-
84945442885
-
Clinical presentation, biochemical, and haematological parameters and their association with outcome in patients with Ebola virus disease: An observational cohort study
-
Hunt L, Gupta-Wright A, Simms V, Tamba F, Knott V, Tamba K, Heisenberg-Mansaray S, Tamba E, Sheriff A, Conteh S, Smith T, Tobin S, Brooks T, Houlihan C, Cummings R, Fletcher T (2015) Clinical presentation, biochemical, and haematological parameters and their association with outcome in patients with Ebola virus disease: an observational cohort study. Lancet Infect Dis 15(11):1292–1299. doi:10.1016/S1473-3099(15)00144-9.
-
(2015)
Lancet Infect Dis
, vol.15
, Issue.11
, pp. 1292-1299
-
-
Hunt, L.1
Gupta-Wright, A.2
Simms, V.3
Tamba, F.4
Knott, V.5
Tamba, K.6
Heisenberg-Mansaray, S.7
Tamba, E.8
Sheriff, A.9
Conteh, S.10
Smith, T.11
Tobin, S.12
Brooks, T.13
Houlihan, C.14
Cummings, R.15
Fletcher, T.16
-
44
-
-
84942194673
-
The effect of dose on the safety and immunogenicity of the VSV Ebola candidate vaccine: A randomised double-blind, placebo-controlled phase 1/2 trial
-
Huttner A, Dayer JA, Yerly S, Combescure C, Auderset F, Desmeules J, Kaya G et al (2015) The effect of dose on the safety and immunogenicity of the VSV Ebola candidate vaccine: a randomised double-blind, placebo-controlled phase 1/2 trial. Lancet Infect Dis 15(10):1156–1166. doi:10.1016/S1473-3099(15)00154-1.
-
(2015)
Lancet Infect Dis
, vol.15
, Issue.10
, pp. 1156-1166
-
-
Huttner, A.1
Dayer, J.A.2
Yerly, S.3
Combescure, C.4
Auderset, F.5
Desmeules, J.6
Kaya, G.7
-
45
-
-
84945435445
-
Post-exposure prophylaxis against Ebola virus disease with experimental antiviral agents: A case-series of health-care workers
-
Jacobs M, Aarons E, Bhagani S, Buchanan R, Cropley I, Hopkins S, Lester R, Martin D, Marshall N, Mepham S, Warren S, Rodger A (2015) Post-exposure prophylaxis against Ebola virus disease with experimental antiviral agents: a case-series of health-care workers. Lancet Infect Dis 15(11):1300–1304. doi:10.1016/s1473-3099(15)00228-5.
-
(2015)
Lancet Infect Dis
, vol.15
, Issue.11
, pp. 1300-1304
-
-
Jacobs, M.1
Aarons, E.2
Bhagani, S.3
Buchanan, R.4
Cropley, I.5
Hopkins, S.6
Lester, R.7
Martin, D.8
Marshall, N.9
Mepham, S.10
Warren, S.11
Rodger, A.12
-
46
-
-
0021839608
-
Endemic Lassa fever in Liberia. IV. Selection of optimally effective plasma for treatment by passive immunization
-
Jahrling PB, Frame JD, Rhoderick JB, Monson MH (1985) Endemic Lassa fever in Liberia. IV. Selection of optimally effective plasma for treatment by passive immunization. Trans R Soc Trop Med Hyg 79(3):380–384.
-
(1985)
Trans R Soc Trop Med Hyg
, vol.79
, Issue.3
, pp. 380-384
-
-
Jahrling, P.B.1
Frame, J.D.2
Rhoderick, J.B.3
Monson, M.H.4
-
47
-
-
0029687228
-
Passive immunization of Ebola virus-infected cynomolgus monkeys with immunoglobulin from hyperimmune horses
-
Jahrling PB, Geisbert J, Swearengen JR, Jaax GP, Lewis T, Huggins JW, Schmidt JJ, LeDuc JW, Peters CJ (1996) Passive immunization of Ebola virus-infected cynomolgus monkeys with immunoglobulin from hyperimmune horses. Arch Virol Suppl 11:135–140.
-
(1996)
Arch Virol Suppl
, vol.11
, pp. 135-140
-
-
Jahrling, P.B.1
Geisbert, J.2
Swearengen, J.R.3
Jaax, G.P.4
Lewis, T.5
Huggins, J.W.6
Schmidt, J.J.7
Leduc, J.W.8
Peters, C.J.9
-
48
-
-
0021355724
-
Passive antibody therapy of Lassa fever in cynomolgus monkeys: Importance of neutralizing antibody and Lassa virus strain
-
Jahrling PB, Peters CJ (1984) Passive antibody therapy of Lassa fever in cynomolgus monkeys: importance of neutralizing antibody and Lassa virus strain. Infect Immun 44(2):528–533.
-
(1984)
Infect Immun
, vol.44
, Issue.2
, pp. 528-533
-
-
Jahrling, P.B.1
Peters, C.J.2
-
49
-
-
38449092660
-
Ebola hemorrhagic fever: Evaluation of passive immunotherapy in nonhuman primates
-
Jahrling PB, Geisbert JB, Swearengen JR, Larsen T, Geisbert TW (2007) Ebola hemorrhagic fever: evaluation of passive immunotherapy in nonhuman primates. J Infect Dis 196(2), S400–3. doi:10.1086/520587.
-
(2007)
J Infect Dis
, vol.196
, Issue.2
, pp. 400
-
-
Jahrling, P.B.1
Geisbert, J.B.2
Swearengen, J.R.3
Larsen, T.4
Geisbert, T.W.5
-
50
-
-
84977646146
-
Inhibitory antibodies targeting emerging viruses: Advancements and mechanisms
-
Jin J, Simmons G (2016) Inhibitory antibodies targeting emerging viruses: advancements and mechanisms. Clin Vaccine Immunol 23(7), 535–539. doi:10.1128/CVI.00136-16.
-
(2016)
Clin Vaccine Immunol
, vol.23
, Issue.7
, pp. 535-539
-
-
Jin, J.1
Simmons, G.2
-
51
-
-
84880544466
-
FDA-approved selective estrogen receptor modulators inhibit Ebola virus infection
-
Johansen LM, Brannan JM, Delos SE, Shoemaker CJ, Stossel A, Lear C, Hoffstrom BG, Dewald LE, Schornberg KL, Scully C, Lehar J, Hensley LE, White JM, Olinger GG (2013) FDA-approved selective estrogen receptor modulators inhibit Ebola virus infection. Sci Transl Med 5 (190):190ra179. doi:10.1126/scitranslmed.3005471.
-
(2013)
Sci Transl Med
, vol.5
, Issue.190
-
-
Johansen, L.M.1
Brannan, J.M.2
Delos, S.E.3
Shoemaker, C.J.4
Stossel, A.5
Lear, C.6
Hoffstrom, B.G.7
Dewald, L.E.8
Schornberg, K.L.9
Scully, C.10
Lehar, J.11
Hensley, L.E.12
White, J.M.13
Olinger, G.G.14
-
52
-
-
84930456828
-
A screen of approved drugs and molecular probes identifies therapeutics with anti-Ebola virus activity
-
Johansen LM, DeWald LE, Shoemaker CJ, Hoffstrom BG, Lear-Rooney CM, Stossel A, Nelson E, Delos SE, Simmons JA, Grenier JM, Pierce LT, Pajouhesh H, Lehar J, Hensley LE, Glass PJ, White JM, Olinger GG (2015) A screen of approved drugs and molecular probes identifies therapeutics with anti-Ebola virus activity. Sci Transl Med 7 (290):290ra289. doi:10.1126/scitranslmed.aaa5597.
-
(2015)
Sci Transl Med
, vol.7
, Issue.290
-
-
Johansen, L.M.1
Dewald, L.E.2
Shoemaker, C.J.3
Hoffstrom, B.G.4
Lear-Rooney, C.M.5
Stossel, A.6
Nelson, E.7
Delos, S.E.8
Simmons, J.A.9
Grenier, J.M.10
Pierce, L.T.11
Pajouhesh, H.12
Lehar, J.13
Hensley, L.E.14
Glass, P.J.15
White, J.M.16
Olinger, G.G.17
-
53
-
-
84901313870
-
Pyridinyl imidazole inhibitors of p38 MAP kinase impair viral entry and reduce cytokine induction by Zaire ebolavirus in human dendritic cells
-
Johnson JC, Martinez O, Honko AN, Hensley LE, Olinger GG, Basler CF (2014) Pyridinyl imidazole inhibitors of p38 MAP kinase impair viral entry and reduce cytokine induction by Zaire ebolavirus in human dendritic cells. Antiviral Res 107:102–109. doi:10.1016/j.antiviral.2014.04.014.
-
(2014)
Antiviral Res
, vol.107
, pp. 102-109
-
-
Johnson, J.C.1
Martinez, O.2
Honko, A.N.3
Hensley, L.E.4
Olinger, G.G.5
Basler, C.F.6
-
54
-
-
0029094959
-
Preparation of hyperimmune horse serum against Ebola virus
-
Krasnianskii BP, Mikhailov VV, Borisevich IV, Gradoboev VN, Evseev AA, Pshenichnov VA (1995) Preparation of hyperimmune horse serum against Ebola virus. Vopr Virusol 40(3):138–140.
-
(1995)
Vopr Virusol
, vol.40
, Issue.3
, pp. 138-140
-
-
Krasnianskii, B.P.1
Mikhailov, V.V.2
Borisevich, I.V.3
Gradoboev, V.N.4
Evseev, A.A.5
Pshenichnov, V.A.6
-
55
-
-
0028389610
-
The isolation of hyperimmune horse serum to the Ebola virus
-
Krasnianskii VP, Mikhailov VV, Borisevich IV, Gradoboev VN, Evseev AA, Pshenichnov VA (1994) The isolation of hyperimmune horse serum to the Ebola virus. Vopr Virusol 39(2):91–92.
-
(1994)
Vopr Virusol
, vol.39
, Issue.2
, pp. 91-92
-
-
Krasnianskii, V.P.1
Mikhailov, V.V.2
Borisevich, I.V.3
Gradoboev, V.N.4
Evseev, A.A.5
Pshenichnov, V.A.6
-
56
-
-
0032993241
-
Preparation and use of hyperimmune serum for prophylaxis and therapy of Ebola virus infections
-
Kudoyarova-Zubavichene NM, Sergeyev NN, Chepurnov AA, Netesov SV (1999) Preparation and use of hyperimmune serum for prophylaxis and therapy of Ebola virus infections. J Infect Dis 179(Suppl 1):218–223. doi:10.1086/514294.
-
(1999)
J Infect Dis
, vol.179
, pp. 218-223
-
-
Kudoyarova-Zubavichene, N.M.1
Sergeyev, N.N.2
Chepurnov, A.A.3
Netesov, S.V.4
-
57
-
-
84942826507
-
Emergence of Ebola Virus Escape Variants in Infected Nonhuman Primates Treated with the MB-003 Antibody Cocktail
-
Kugelman JR, Kugelman-Tonos J, Ladner JT, Pettit J, Keeton CM, Nagle ER, Garcia KY, Froude JW, Kuehne AI, Kuhn JH, Bavari S, Zeitlin L, Dye JM, Olinger GG, Sanchez-Lockhart M, Palacios GF (2015) Emergence of Ebola Virus Escape Variants in Infected Nonhuman Primates Treated with the MB-003 Antibody Cocktail. Cell reports 12(12):2111–2120. doi:10.1016/j.celrep.2015.08.038.
-
(2015)
Cell Reports
, vol.12
, Issue.12
, pp. 2111-2120
-
-
Kugelman, J.R.1
Kugelman-Tonos, J.2
Ladner, J.T.3
Pettit, J.4
Keeton, C.M.5
Nagle, E.R.6
Garcia, K.Y.7
Froude, J.W.8
Kuehne, A.I.9
Kuhn, J.H.10
Bavari, S.11
Zeitlin, L.12
Dye, J.M.13
Olinger, G.G.14
Sanchez-Lockhart, M.15
Palacios, G.F.16
-
58
-
-
38449101458
-
Pathologic findings associated with delayed death in nonhuman primates experimentally infected with Zaire Ebola virus
-
Larsen T, Stevens EL, Davis KJ, Geisbert JB, Daddario-DiCaprio KM, Jahrling PB, Hensley LE, Geisbert TW (2007) Pathologic findings associated with delayed death in nonhuman primates experimentally infected with Zaire Ebola virus. J Infect Dis 196(Suppl 2):323–328. doi:10.1086/520589.
-
(2007)
J Infect Dis
, vol.196
, pp. 323-328
-
-
Larsen, T.1
Stevens, E.L.2
Davis, K.J.3
Geisbert, J.B.4
Daddario-Dicaprio, K.M.5
Jahrling, P.B.6
Hensley, L.E.7
Geisbert, T.W.8
-
59
-
-
84979586876
-
Ebola virus disease and critical illness
-
Leligdowicz A, Fischer WA, 2nd Uyeki TM, Fletcher TE, Adhikari NK, Portella G, Lamontagne F, Clement C, Jacob ST, Rubinson L, Vanderschuren A, Hajek J, Murthy S, Ferri M, Crozier I, Ibrahima E, Lamah MC, Schieffelin JS, Brett-Major D, Bausch DG, Shindo N, Chan AK, O’Dempsey T, Mishra S, Jacobs M, Dickson S, Lyon GM 3rd, Fowler RA (2016) Ebola virus disease and critical illness. Crit Care 20(1), 217. doi:10.1186/s13054-016-1325-2.
-
(2016)
Crit Care
, vol.20
, Issue.1
-
-
Leligdowicz, A.1
Fischer, W.A.T.M.2
Uyek, T.E.3
Adhikari, N.K.4
Portella, G.5
Lamontagne, F.6
Clement, C.7
Jacob, S.T.8
Rubinson, L.9
Vanderschuren, A.10
Hajek, J.11
Murthy, S.12
Ferri, M.13
Crozier, I.14
Ibrahima, E.15
Lamah, M.C.16
Schieffelin, J.S.17
Brett-Major, D.18
Bausch, D.G.19
Shindo, N.20
Chan, A.K.21
O’dempsey, T.22
Mishra, S.23
Jacobs, M.24
Dickson, S.25
Lyon, G.M.26
Fowler, R.A.27
more..
-
60
-
-
84938255251
-
Characteristics and Clinical Management of a Cluster of 3 Patients With Ebola Virus Disease, Including the First Domestically Acquired Cases in the United States
-
Liddell AM, Davey RT Jr, Mehta AK, Varkey JB, Kraft CS, Tseggay GK, Badidi O, Faust AC, Brown KV, Suffredini AF, Barrett K, Wolcott MJ, Marconi VC, Lyon GM 3rd, Weinstein GL, Weinmeister K, Sutton S, Hazbun M, Albarino CG, Reed Z, Cannon D, Stroher U, Feldman M, Ribner BS, Lane HC, Fauci AS, Uyeki TM (2015) Characteristics and Clinical Management of a Cluster of 3 Patients With Ebola Virus Disease, Including the First Domestically Acquired Cases in the United States. Ann Intern Med 163(2):81–90. doi:10.7326/M15-0530.
-
(2015)
Ann Intern Med
, vol.163
, Issue.2
, pp. 81-90
-
-
Liddell, A.M.1
Davey, R.T.2
Mehta, A.K.3
Varkey, J.B.4
Kraft, C.S.5
Tseggay, G.K.6
Badidi, O.7
Faust, A.C.8
Brown, K.V.9
Suffredini, A.F.10
Barrett, K.11
Wolcott, M.J.12
Marconi, V.C.13
Lyon, G.M.14
Weinstein, G.L.15
Weinmeister, K.16
Sutton, S.17
Hazbun, M.18
Albarino, C.G.19
Reed, Z.20
Cannon, D.21
Stroher, U.22
Feldman, M.23
Ribner, B.S.24
Lane, H.C.25
Fauci, A.S.26
Uyeki, T.M.27
more..
-
61
-
-
84955304814
-
Ebola virus infection: Review of the Pharmacokinetic and Pharmacodynamic properties of drugs considered for testing in human efficacy trials
-
Madelain V, Nguyen TH, Olivo A, de Lamballerie X, Guedj J, Taburet AM, Mentre F (2016) Ebola virus infection: review of the Pharmacokinetic and Pharmacodynamic properties of drugs considered for testing in human efficacy trials. Clin Pharmacokinet 55(8):907–923. doi:10.1007/s40262-015-0364-1.
-
(2016)
Clin Pharmacokinet
, vol.55
, Issue.8
, pp. 907-923
-
-
Madelain, V.1
Nguyen, T.H.2
Olivo, A.3
De Lamballerie, X.4
Guedj, J.5
Taburet, A.M.6
Mentre, F.7
-
62
-
-
2542617048
-
Developing principles for emergency prevention and treatment of Ebola fever
-
Markin VA, Mikhailov VV, Krasnianskii VP, Borisevich IV, Firsova IV (1997) Developing principles for emergency prevention and treatment of Ebola fever. Vopr Virusol 42(1):31–34.
-
(1997)
Vopr Virusol
, vol.42
, Issue.1
, pp. 31-34
-
-
Markin, V.A.1
Mikhailov, V.V.2
Krasnianskii, V.P.3
Borisevich, I.V.4
Firsova, I.V.5
-
63
-
-
84959179767
-
Early clinical sequelae of Ebola virus disease in Sierra Leone: A cross-sectional study
-
Mattia JG, Vandy MJ, Chang JC, Platt DE, Dierberg K, Bausch DG, Brooks T, Conteh S, Crozier I, Fowler RA, Kamara AP, Kang C, Mahadevan S, Mansaray Y, Marcell L, McKay G, O’Dempsey T, Parris V, Pinto R, Rangel A, Salam AP, Shantha J, Wolfman V, Yeh S, Chan AK, Mishra S (2016) Early clinical sequelae of Ebola virus disease in Sierra Leone: a cross-sectional study. Lancet Infect Dis 16(3), 331–338. doi:10.1016/S1473-3099(15)00489-2.
-
(2016)
Lancet Infect Dis
, vol.16
, Issue.3
, pp. 331-338
-
-
Mattia, J.G.1
Vandy, M.J.2
Chang, J.C.3
Platt, D.E.4
Dierberg, K.5
Bausch, D.G.6
Brooks, T.7
Conteh, S.8
Crozier, I.9
Fowler, R.A.10
Kamara, A.P.11
Kang, C.12
Mahadevan, S.13
Mansaray, Y.14
Marcell, L.15
McKay, G.16
O’dempsey, T.17
Parris, V.18
Pinto, R.19
Rangel, A.20
Salam, A.P.21
Shantha, J.22
Wolfman, V.23
Yeh, S.24
Chan, A.K.25
Mishra, S.26
more..
-
64
-
-
84969416041
-
A Rapid Screening Assay Identifies Monotherapy with Interferon-ss and Combination Therapies with Nucleoside Analogs as Effective Inhibitors of Ebola Virus
-
McCarthy SD, Majchrzak-Kita B, Racine T, Kozlowski HN, Baker DP, Hoenen T, Kobinger GP, Fish EN, Branch DR (2016) A Rapid Screening Assay Identifies Monotherapy with Interferon-ss and Combination Therapies with Nucleoside Analogs as Effective Inhibitors of Ebola Virus. PLoS Negl Trop Dis 10(1):e0004364. doi:10.1371/journal.pntd.0004364.
-
(2016)
Plos Negl Trop Dis
, vol.10
, Issue.1
-
-
McCarthy, S.D.1
Majchrzak-Kita, B.2
Racine, T.3
Kozlowski, H.N.4
Baker, D.P.5
Hoenen, T.6
Kobinger, G.P.7
Fish, E.N.8
Branch, D.R.9
-
65
-
-
84949504134
-
The lipid moiety of brincidofovir is required for in vitro antiviral activity against Ebola virus
-
McMullan LK, Flint M, Dyall J, Albarino C, Olinger GG, Foster S, Sethna P, Hensley LE, Nichol ST, Lanier ER, Spiropoulou CF (2016) The lipid moiety of brincidofovir is required for in vitro antiviral activity against Ebola virus. Antiviral Res 125:71–78. doi:10.1016/j.antiviral.2015.10.010.
-
(2016)
Antiviral Res
, vol.125
, pp. 71-78
-
-
McMullan, L.K.1
Flint, M.2
Dyall, J.3
Albarino, C.4
Olinger, G.G.5
Foster, S.6
Sethna, P.7
Hensley, L.E.8
Nichol, S.T.9
Lanier, E.R.10
Spiropoulou, C.F.11
-
66
-
-
0028398912
-
The evaluation in hamadryas baboons of the possibility for the specific prevention of Ebola fever
-
Mikhailov VV, Borisevich IV, Chernikova NK, Potryvaeva NV, Krasnianskii VP (1994) The evaluation in hamadryas baboons of the possibility for the specific prevention of Ebola fever. Vopr Virusol 39(2):82–84.
-
(1994)
Vopr Virusol
, vol.39
, Issue.2
, pp. 82-84
-
-
Mikhailov, V.V.1
Borisevich, I.V.2
Chernikova, N.K.3
Potryvaeva, N.V.4
Krasnianskii, V.P.5
-
67
-
-
84990982238
-
Passive Immunotherapy: Assessment of Convalescent Serum Against Ebola Virus Makona Infection in Nonhuman Primates
-
Mire CE, Geisbert JB, Agans KN, Thi EP, Lee AC, Fenton KA, Geisbert TW (2016) Passive Immunotherapy: assessment of Convalescent Serum Against Ebola Virus Makona Infection in Nonhuman Primates. J Infect Dis 214(Suppl 3):S367–S374. doi:10.1093/infdis/jiw333.
-
(2016)
J Infect Dis
, vol.214
, pp. S367-S374
-
-
Mire, C.E.1
Geisbert, J.B.2
Agans, K.N.3
Thi, E.P.4
Lee, A.C.5
Fenton, K.A.6
Geisbert, T.W.7
-
68
-
-
84863230082
-
Filoviruses require endosomal cysteine proteases for entry but exhibit distinct protease preferences
-
Misasi J, Chandran K, Yang JY, Considine B, Filone CM, Cote M, Sullivan N, Fabozzi G, Hensley L, Cunningham J (2012) Filoviruses require endosomal cysteine proteases for entry but exhibit distinct protease preferences. J Virol 86(6):3284–3292. doi:10.1128/jvi.06346-11.
-
(2012)
J Virol
, vol.86
, Issue.6
, pp. 3284-3292
-
-
Misasi, J.1
Chandran, K.2
Yang, J.Y.3
Considine, B.4
Filone, C.M.5
Cote, M.6
Sullivan, N.7
Fabozzi, G.8
Hensley, L.9
Cunningham, J.10
-
69
-
-
84992160850
-
Monoclonal antibodies for the treatment of Ebola virus disease
-
Moekotte AL, Huson MA, van der Ende AJ, Agnandji ST, Huizenga E, Goorhuis A, Grobusch MP (2016) Monoclonal antibodies for the treatment of Ebola virus disease. Expert Opin Investig Drugs 25(11), 1325-1335. doi:10.1080/13543784.2016.1240785.
-
(2016)
Expert Opin Investig Drugs
, vol.25
, Issue.11
, pp. 1325-1335
-
-
Moekotte, A.L.1
Huson, M.A.2
Van Der Ende, A.J.3
Agnandji, S.T.4
Huizenga, E.5
Goorhuis, A.6
Grobusch, M.P.7
-
70
-
-
0033062193
-
Treatment of Ebola hemorrhagic fever with blood transfusions from convalescent patients. International Scientific and Technical Committee
-
Mupapa K, Massamba M, Kibadi K, Kuvula K, Bwaka A, Kipasa M, Colebunders R, Muyembe-Tamfum JJ (1999) Treatment of Ebola hemorrhagic fever with blood transfusions from convalescent patients. International Scientific and Technical Committee. J Infect Dis 179(Suppl 1):S18–23. doi:10.1086/514298.
-
(1999)
J Infect Dis
, vol.179
, pp. S18-S23
-
-
Mupapa, K.1
Massamba, M.2
Kibadi, K.3
Kuvula, K.4
Bwaka, A.5
Kipasa, M.6
Colebunders, R.7
Muyembe-Tamfum, J.J.8
-
71
-
-
84896129506
-
Successful treatment of advanced Ebola virus infection with T-705 (Favipiravir) in a small animal model
-
Oestereich L, Ludtke A, Wurr S, Rieger T, Munoz-Fontela C, Gunther S (2014) Successful treatment of advanced Ebola virus infection with T-705 (favipiravir) in a small animal model. Antiviral Res 105:17–21. doi:10.1016/j.antiviral.2014.02.014.
-
(2014)
Antiviral Res
, vol.105
, pp. 17-21
-
-
Oestereich, L.1
Ludtke, A.2
Wurr, S.3
Rieger, T.4
Munoz-Fontela, C.5
Gunther, S.6
-
72
-
-
84868149422
-
Delayed treatment of Ebola virus infection with plant-derived monoclonal antibodies provides protection in rhesus macaques
-
Olinger GG Jr, Pettitt J, Kim D, Working C, Bohorov O, Bratcher B, Hiatt E, Hume SD, Johnson AK, Morton J, Pauly M, Whaley KJ, Lear CM, Biggins JE, Scully C, Hensley L, Zeitlin L (2012) Delayed treatment of Ebola virus infection with plant-derived monoclonal antibodies provides protection in rhesus macaques. Proc Natl Acad Sci USA 109(44):18030–18035. doi:10.1073/pnas.1213709109.
-
(2012)
Proc Natl Acad Sci USA
, vol.109
, Issue.44
, pp. 18030-18035
-
-
Olinger, G.G.1
Pettitt, J.2
Kim, D.3
Working, C.4
Bohorov, O.5
Bratcher, B.6
Hiatt, E.7
Hume, S.D.8
Johnson, A.K.9
Morton, J.10
Pauly, M.11
Whaley, K.J.12
Lear, C.M.13
Biggins, J.E.14
Scully, C.15
Hensley, L.16
Zeitlin, L.17
-
73
-
-
0036100307
-
Pre- and postexposure prophylaxis of Ebola virus infection in an animal model by passive transfer of a neutralizing human antibody
-
Parren PW, Geisbert TW, Maruyama T, Jahrling PB, Burton DR (2002) Pre- and postexposure prophylaxis of Ebola virus infection in an animal model by passive transfer of a neutralizing human antibody. J Virol 76(12):6408–6412.
-
(2002)
J Virol
, vol.76
, Issue.12
, pp. 6408-6412
-
-
Parren, P.W.1
Geisbert, T.W.2
Maruyama, T.3
Jahrling, P.B.4
Burton, D.R.5
-
74
-
-
84961144521
-
Targeting Innate Immunity for Antiviral Therapy through Small Molecule Agonists of the RLR Pathway
-
Pattabhi S, Wilkins CR, Dong R, Knoll ML, Posakony J, Kaiser S, Mire CE, Wang ML, Ireton RC, Geisbert TW, Bedard KM, Iadonato SP, Loo YM, Gale M Jr. (2016) Targeting Innate Immunity for Antiviral Therapy through Small Molecule Agonists of the RLR Pathway. J Virol 90(5):2372–2387. doi:10.1128/jvi.02202-15.
-
(2016)
J Virol
, vol.90
, Issue.5
, pp. 2372-2387
-
-
Pattabhi, S.1
Wilkins, C.R.2
Dong, R.3
Knoll, M.L.4
Posakony, J.5
Kaiser, S.6
Mire, C.E.7
Wang, M.L.8
Ireton, R.C.9
Geisbert, T.W.10
Bedard, K.M.11
Iadonato, S.P.12
Loo, Y.M.13
Gale, M.14
-
75
-
-
84961160885
-
The Synthetic Antiviral Drug Arbidol Inhibits Globally Prevalent Pathogenic Viruses
-
Pecheur EI, Borisevich V, Halfmann P, Morrey JD, Smee DF, Prichard M, Mire CE, Kawaoka Y, Geisbert TW, Polyak SJ (2016) The Synthetic Antiviral Drug Arbidol Inhibits Globally Prevalent Pathogenic Viruses. J Virol 90(6):3086–3092. doi:10.1128/jvi.02077-15.
-
(2016)
J Virol
, vol.90
, Issue.6
, pp. 3086-3092
-
-
Pecheur, E.I.1
Borisevich, V.2
Halfmann, P.3
Morrey, J.D.4
Smee, D.F.5
Prichard, M.6
Mire, C.E.7
Kawaoka, Y.8
Geisbert, T.W.9
Polyak, S.J.10
-
76
-
-
84883864987
-
Therapeutic intervention of Ebola virus infection in rhesus macaques with the MB-003 monoclonal antibody cocktail
-
Pettitt J, Zeitlin L, Kim DH, Working C, Johnson JC, Bohorov O, Bratcher B, Hiatt E, Hume SD, Johnson AK, Morton J, Pauly MH, Whaley KJ, Ingram MF, Zovanyi A, Heinrich M, Piper A, Zelko J, Olinger GG (2013) Therapeutic intervention of Ebola virus infection in rhesus macaques with the MB-003 monoclonal antibody cocktail. Science translational medicine 5 (199):199ra113. doi:10.1126/scitranslmed.3006608.
-
(2013)
Science Translational Medicine
, vol.5
, Issue.199
-
-
Pettitt, J.1
Zeitlin, L.2
Kim, D.H.3
Working, C.4
Johnson, J.C.5
Bohorov, O.6
Bratcher, B.7
Hiatt, E.8
Hume, S.D.9
Johnson, A.K.10
Morton, J.11
Pauly, M.H.12
Whaley, K.J.13
Ingram, M.F.14
Zovanyi, A.15
Heinrich, M.16
Piper, A.17
Zelko, J.18
Olinger, G.G.19
-
77
-
-
84862525229
-
Successful treatment of ebola virus-infected cynomolgus macaques with monoclonal antibodies
-
Qiu X, Audet J, Wong G, Pillet S, Bello A, Cabral T, Strong JE, Plummer F, Corbett CR, Alimonti JB, Kobinger GP (2012a) Successful treatment of ebola virus-infected cynomolgus macaques with monoclonal antibodies. Science translational medicine 4 (138):138ra181. doi:10.1126/scitranslmed.3003876.
-
(2012)
Science Translational Medicine
, vol.4
, Issue.138
-
-
Qiu, X.1
Audet, J.2
Wong, G.3
Pillet, S.4
Bello, A.5
Cabral, T.6
Strong, J.E.7
Plummer, F.8
Corbett, C.R.9
Alimonti, J.B.10
Kobinger, G.P.11
-
78
-
-
84859206023
-
Ebola GP-specific monoclonal antibodies protect mice and guinea pigs from lethal Ebola virus infection
-
Qiu X, Fernando L, Melito PL, Audet J, Feldmann H, Kobinger G, Alimonti JB, Jones SM (2012b) Ebola GP-specific monoclonal antibodies protect mice and guinea pigs from lethal Ebola virus infection. PLoS neglected tropical diseases 6(3):e1575. doi:10.1371/journal.pntd.0001575.
-
(2012)
Plos Neglected Tropical Diseases
, vol.6
, Issue.3
-
-
Qiu, X.1
Fernando, L.2
Melito, P.L.3
Audet, J.4
Feldmann, H.5
Kobinger, G.6
Alimonti, J.B.7
Jones, S.M.8
-
79
-
-
84907263545
-
Reversion of advanced Ebola virus disease in nonhuman primates with ZMapp
-
Qiu X, Wong G, Audet J, Bello A, Fernando L, Alimonti JB, Fausther-Bovendo H, Wei H, Aviles J, Hiatt E, Johnson A, Morton J, Swope K, Bohorov O, Bohorova N, Goodman C, Kim D, Pauly MH, Velasco J, Pettitt J, Olinger GG, Whaley K, Xu B, Strong JE, Zeitlin L, Kobinger GP (2014) Reversion of advanced Ebola virus disease in nonhuman primates with ZMapp. Nature 514(7520):47–53. doi:10.1038/nature13777.
-
(2014)
Nature
, vol.514
, Issue.7520
, pp. 47-53
-
-
Qiu, X.1
Wong, G.2
Audet, J.3
Bello, A.4
Fernando, L.5
Alimonti, J.B.6
Fausther-Bovendo, H.7
Wei, H.8
Aviles, J.9
Hiatt, E.10
Johnson, A.11
Morton, J.12
Swope, K.13
Bohorov, O.14
Bohorova, N.15
Goodman, C.16
Kim, D.17
Pauly, M.H.18
Velasco, J.19
Pettitt, J.20
Olinger, G.G.21
Whaley, K.22
Xu, B.23
Strong, J.E.24
Zeitlin, L.25
Kobinger, G.P.26
more..
-
80
-
-
84911371938
-
Host genetic diversity enables Ebola hemorrhagic fever pathogenesis and resistance
-
Rasmussen AL, Okumura A, Ferris MT, Green R, Feldmann F, Kelly SM, Scott DP, Safronetz D, Haddock E, LaCasse R, Thomas MJ, Sova P, Carter VS, Weiss JM, Miller DR, Shaw GD, Korth MJ, Heise MT, Baric RS, de Villena FP, Feldmann H, Katze MG (2014) Host genetic diversity enables Ebola hemorrhagic fever pathogenesis and resistance. Sci 346(6212), 987–991. doi:10.1126/science.1259595.
-
(2014)
Sci
, vol.346
, Issue.6212
, pp. 987-991
-
-
Rasmussen, A.L.1
Okumura, A.2
Ferris, M.T.3
Green, R.4
Feldmann, F.5
Kelly, S.M.6
Scott, D.P.7
Safronetz, D.8
Haddock, E.9
Lacasse, R.10
Thomas, M.J.11
Sova, P.12
Carter, V.S.13
Weiss, J.M.14
Miller, D.R.15
Shaw, G.D.16
Korth, M.J.17
Heise, M.T.18
Baric, R.S.19
De Villena, F.P.20
Feldmann, H.21
Katze, M.G.22
more..
-
81
-
-
84948965862
-
Interferon-gamma Inhibits Ebola Virus Infection
-
Rhein BA, Powers LS, Rogers K, Anantpadma M, Singh BK, Sakurai Y, Bair T, Miller-Hunt C, Sinn P, Davey RA, Monick MM, Maury W (2015) Interferon-gamma Inhibits Ebola Virus Infection. PLoS Pathog 11(11):e1005263. doi:10.1371/journal.ppat.1005263.
-
(2015)
Plos Pathog
, vol.11
, Issue.11
-
-
Rhein, B.A.1
Powers, L.S.2
Rogers, K.3
Anantpadma, M.4
Singh, B.K.5
Sakurai, Y.6
Bair, T.7
Miller-Hunt, C.8
Sinn, P.9
Davey, R.A.10
Monick, M.M.11
Maury, W.12
-
82
-
-
85009749015
-
A systematic review of Ebola treatment trials to assess the extent to which they adhere to ethical guidelines
-
Richardson T, Johnston AM, Draper H (2017) A systematic review of Ebola treatment trials to assess the extent to which they adhere to ethical guidelines. PLoS One 12(1), e0168975. doi:10.1371/journal.pone.0168975.
-
(2017)
Plos One
, vol.12
, Issue.1
-
-
Richardson, T.1
Johnston, A.M.2
Draper, H.3
-
83
-
-
84957583560
-
A US Food and Drug Administration perspective on evaluating medical products for Ebola
-
Russek-Cohen E, Rubin D, Price D, Sun W, Cox E, Borio L (2016) A US Food and Drug Administration perspective on evaluating medical products for Ebola. Clinical trials 13(1):105–109. doi:10.1177/1740774515620613.
-
(2016)
Clinical Trials
, vol.13
, Issue.1
, pp. 105-109
-
-
Russek-Cohen, E.1
Rubin, D.2
Price, D.3
Sun, W.4
Cox, E.5
Borio, L.6
-
84
-
-
50849144350
-
Phosphoinositide-3 kinase-Akt pathway controls cellular entry of Ebola virus
-
Saeed MF, Kolokoltsov AA, Freiberg AN, Holbrook MR, Davey RA (2008) Phosphoinositide-3 kinase-Akt pathway controls cellular entry of Ebola virus. PLoS Pathog 4(8):e1000141. doi:10.1371/journal.ppat.1000141.
-
(2008)
Plos Pathog
, vol.4
, Issue.8
-
-
Saeed, M.F.1
Kolokoltsov, A.A.2
Freiberg, A.N.3
Holbrook, M.R.4
Davey, R.A.5
-
85
-
-
9944235581
-
Palivizumab for respiratory syncytial virus prophylaxis
-
Sandrittez T (1999) Palivizumab for respiratory syncytial virus prophylaxis. J Pediatr Health Care 13 (4):191–195; quiz 196–197. doi:10.1016/S0891-5245(99)90039-1.
-
(1999)
J Pediatr Health Care
, vol.13
, Issue.4
-
-
Sandrittez, T.1
-
86
-
-
85015834059
-
Ebola virus persistence in breast milk after no reported illness: A likely source of virus transmission from mother to child
-
Sissoko D, Keita M, Diallo B, Aliabadi N, Fitter DL, Dahl BA, Bore JA, Koundouno FR, Singethan K, Meisel S, Enkirch T, Mazzarelli A, Amburgey V, Faye O, Sall AA, Magassouba N, Carroll MW, Anglaret X, Malvy D, Formenty P, Aylward RB, Keita S, Djingarey MH, Loman NJ, Gunther S, Duraffour S (2016a) Ebola virus persistence in breast milk after no reported illness: a likely source of virus transmission from mother to child. Clin Infect Dis Official Publication Infect Dis Soc Am. doi:10.1093/cid/ciw793.
-
(2016)
Clin Infect Dis Official Publication Infect Dis Soc Am
-
-
Sissoko, D.1
Keita, M.2
Diallo, B.3
Aliabadi, N.4
Fitter, D.L.5
Dahl, B.A.6
Bore, J.A.7
Koundouno, F.R.8
Singethan, K.9
Meisel, S.10
Enkirch, T.11
Mazzarelli, A.12
Amburgey, V.13
Faye, O.14
Sall, A.A.15
Magassouba, N.16
Carroll, M.W.17
Anglaret, X.18
Malvy, D.19
Formenty, P.20
Aylward, R.B.21
Keita, S.22
Djingarey, M.H.23
Loman, N.J.24
Gunther, S.25
Duraffour, S.26
more..
-
87
-
-
84962128607
-
Experimental treatment with favipiravir for Ebola virus disease (The JIKI Trial): A historically controlled, single-arm proof-of-concept trial in Guinea
-
Sissoko D, Laouenan C, Folkesson E, M’lebing AB, Beavogui AH, Laouenan S, Carazo S et al (2016b) Experimental treatment with favipiravir for Ebola virus disease (the JIKI Trial): a historically controlled, single-arm proof-of-concept trial in Guinea. PLoS Med 13(3):e1001967. doi:10.1371/journal.pmed.1001967.
-
(2016)
Plos Med
, vol.13
, Issue.3
-
-
Sissoko, D.1
Laouenan, C.2
Folkesson, E.3
M’Lebing, A.B.4
Beavogui, A.H.5
Laouenan, S.6
Carazo, S.7
-
88
-
-
77954951982
-
Inhibition of heat-shock protein 90 reduces Ebola virus replication
-
Smith DR, McCarthy S, Chrovian A, Olinger G, Stossel A, Geisbert TW, Hensley LE, Connor JH (2010) Inhibition of heat-shock protein 90 reduces Ebola virus replication. Antiviral Res 87(2):187–194. doi:10.1016/j.antiviral.2010.04.015.
-
(2010)
Antiviral Res
, vol.87
, Issue.2
, pp. 187-194
-
-
Smith, D.R.1
McCarthy, S.2
Chrovian, A.3
Olinger, G.4
Stossel, A.5
Geisbert, T.W.6
Hensley, L.E.7
Connor, J.H.8
-
89
-
-
84878907971
-
Interferon-beta therapy prolongs survival in rhesus macaque models of Ebola and Marburg hemorrhagic fever
-
Smith LM, Hensley LE, Geisbert TW, Johnson J, Stossel A, Honko A, Yen JY, Geisbert J, Paragas J, Fritz E, Olinger G, Young HA, Rubins KH, Karp CL (2013) Interferon-beta therapy prolongs survival in rhesus macaque models of Ebola and Marburg hemorrhagic fever. J Infect Dis 208(2), 310–318. doi:10.1093/infdis/jis921.
-
(2013)
J Infect Dis
, vol.208
, Issue.2
, pp. 310-318
-
-
Smith, L.M.1
Hensley, L.E.2
Geisbert, T.W.3
Johnson, J.4
Stossel, A.5
Honko, A.6
Yen, J.Y.7
Geisbert, J.8
Paragas, J.9
Fritz, E.10
Olinger, G.11
Young, H.A.12
Rubins, K.H.13
Karp, C.L.14
-
90
-
-
84896692632
-
Post-exposure efficacy of oral T-705 (Favipiravir) against inhalational Ebola virus infection in a mouse model
-
Smither SJ, Eastaugh LS, Steward JA, Nelson M, Lenk RP, Lever MS (2014) Post-exposure efficacy of oral T-705 (Favipiravir) against inhalational Ebola virus infection in a mouse model. Antiviral Res 104:153–155. doi:10.1016/j.antiviral.2014.01.012.
-
(2014)
Antiviral Res
, vol.104
, pp. 153-155
-
-
Smither, S.J.1
Eastaugh, L.S.2
Steward, J.A.3
Nelson, M.4
Lenk, R.P.5
Lever, M.S.6
-
91
-
-
57349140230
-
Targeting inside-out phosphatidylserine as a therapeutic strategy for viral diseases
-
Soares MM, King SW, Thorpe PE (2008) Targeting inside-out phosphatidylserine as a therapeutic strategy for viral diseases. Nat Med 14(12):1357–1362. doi:10.1038/nm.1885.
-
(2008)
Nat Med
, vol.14
, Issue.12
, pp. 1357-1362
-
-
Soares, M.M.1
King, S.W.2
Thorpe, P.E.3
-
92
-
-
84880912628
-
Persistent immune responses after Ebola virus infection
-
Sobarzo A, Ochayon DE, Lutwama JJ, Balinandi S, Guttman O, Marks RS, Kuehne AI, Dye JM, Yavelsky V, Lewis EC, Lobel L (2013) Persistent immune responses after Ebola virus infection. The New England journal of medicine 369(5):492–493. doi:10.1056/NEJMc1300266.
-
(2013)
The New England Journal of Medicine
, vol.369
, Issue.5
, pp. 492-493
-
-
Sobarzo, A.1
Ochayon, D.E.2
Lutwama, J.J.3
Balinandi, S.4
Guttman, O.5
Marks, R.S.6
Kuehne, A.I.7
Dye, J.M.8
Yavelsky, V.9
Lewis, E.C.10
Lobel, L.11
-
93
-
-
84941894175
-
Critical care for multiple organ failure secondary to Ebola virus disease in the United States
-
Sueblinvong V, Johnson DW, Weinstein GL, Connor MJ Jr, Crozier I, Liddell AM, Franch HA, Wall BR, Kalil AC, Feldman M, Lisco SJ, Sevransky JE (2015) Critical care for multiple organ failure secondary to Ebola virus disease in the United States. Crit Care Med 43(10):2066–2075. doi:10.1097/CCM.0000000000001197.
-
(2015)
Crit Care Med
, vol.43
, Issue.10
, pp. 2066-2075
-
-
Sueblinvong, V.1
Johnson, D.W.2
Weinstein, G.L.3
Connor, M.J.4
Crozier, I.5
Liddell, A.M.6
Franch, H.A.7
Wall, B.R.8
Kalil, A.C.9
Feldman, M.10
Lisco, S.J.11
Sevransky, J.E.12
-
94
-
-
63449099709
-
Chemical modifications of antisense morpholino oligomers enhance their efficacy against Ebola virus infection
-
Swenson DL, Warfield KL, Warren TK, Lovejoy C, Hassinger JN, Ruthel G, Blouch RE, Moulton HM, Weller DD, Iversen PL, Bavari S (2009) Chemical modifications of antisense morpholino oligomers enhance their efficacy against Ebola virus infection. Antimicrob Agents Chemother 53(5):2089–2099. doi:10.1128/aac.00936-08.
-
(2009)
Antimicrob Agents Chemother
, vol.53
, Issue.5
, pp. 2089-2099
-
-
Swenson, D.L.1
Warfield, K.L.2
Warren, T.K.3
Lovejoy, C.4
Hassinger, J.N.5
Ruthel, G.6
Blouch, R.E.7
Moulton, H.M.8
Weller, D.D.9
Iversen, P.L.10
Bavari, S.11
-
95
-
-
84929505474
-
Lipid Nanoparticle siRNA Treatment Ebola-Virus-Makona-Infected Nonhuman Primates
-
Thi EP, Mire CE, Lee AC, Geisbert JB, Zhou JZ, Agans KN, Snead NM, Deer DJ, Barnard TR, Fenton KA, MacLachlan I, Geisbert TW (2015) Lipid Nanoparticle siRNA Treatment Ebola-Virus-Makona-Infected Nonhuman Primates. Nature 521(7552):362–365. doi:10.1038/nature14442.
-
(2015)
Nature
, vol.521
, Issue.7552
, pp. 362-365
-
-
Thi, E.P.1
Mire, C.E.2
Lee, A.C.3
Geisbert, J.B.4
Zhou, J.Z.5
Agans, K.N.6
Snead, N.M.7
Deer, D.J.8
Barnard, T.R.9
Fenton, K.A.10
Maclachlan, I.11
Geisbert, T.W.12
-
96
-
-
77955507186
-
Targeting anionic phospholipids on tumor blood vessels and tumor cells
-
Thorpe PE (2010) Targeting anionic phospholipids on tumor blood vessels and tumor cells. Thromb Res 125(Suppl 2):134–137. doi:10.1016/S0049-3848(10)70031-1.
-
(2010)
Thromb Res
, vol.125
, pp. 134-137
-
-
Thorpe, P.E.1
-
97
-
-
85002487975
-
Efficacy of Convalescent Plasma in Relation to Dose of Ebola Virus Antibodies
-
van Griensven J, Edwards T, Baize S, Ebola-Tx C (2016a) Efficacy of Convalescent Plasma in Relation to Dose of Ebola Virus Antibodies. New Engl J Med 375(23):2307–2309. doi:10.1056/NEJMc1609116.
-
(2016)
New Engl J Med
, vol.375
, Issue.23
, pp. 2307-2309
-
-
Van Griensven, J.1
Edwards, T.2
Baize, S.3
Ebola-Tx, C.4
-
98
-
-
84954049384
-
Evaluation of Convalescent Plasma for Ebola Virus Disease in Guinea
-
van Griensven J, Edwards T, de Lamballerie X, Semple MG, Gallian P, Baize S, Horby PW, Raoul H, Magassouba N, Antierens A, Lomas C, Faye O, Sall AA, Fransen K, Buyze J, Ravinetto R, Tiberghien P, Claeys Y, De Crop M, Lynen L, Bah EI, Smith PG, Delamou A, De Weggheleire A, Haba N, Ebola-Tx C (2016b) Evaluation of Convalescent Plasma for Ebola Virus Disease in Guinea. New Engl J Med 374(1):33–42. doi:10.1056/NEJMoa1511812.
-
(2016)
New Engl J Med
, vol.374
, Issue.1
, pp. 33-42
-
-
Van Griensven, J.1
Edwards, T.2
De Lamballerie, X.3
Semple, M.G.4
Gallian, P.5
Baize, S.6
Horby, P.W.7
Raoul, H.8
Magassouba, N.9
Antierens, A.10
Lomas, C.11
Faye, O.12
Sall, A.A.13
Fransen, K.14
Buyze, J.15
Ravinetto, R.16
Tiberghien, P.17
Claeys, Y.18
De Crop, M.19
Lynen, L.20
Bah, E.I.21
Smith, P.G.22
Delamou, A.23
De Weggheleire, A.24
Haba, N.25
Ebola-Tx, C.26
more..
-
100
-
-
33644653708
-
Gene-specific countermeasures against Ebola virus based on antisense phosphorodiamidate morpholino oligomers
-
Warfield KL, Swenson DL, Olinger GG, Nichols DK, Pratt WD, Blouch R, Stein DA, Aman MJ, Iversen PL, Bavari S (2006) Gene-specific countermeasures against Ebola virus based on antisense phosphorodiamidate morpholino oligomers. PLoS Pathog 2(1):e1. doi:10.1371/journal.ppat.0020001.
-
(2006)
Plos Pathog
, vol.2
, Issue.1
-
-
Warfield, K.L.1
Swenson, D.L.2
Olinger, G.G.3
Nichols, D.K.4
Pratt, W.D.5
Blouch, R.6
Stein, D.A.7
Aman, M.J.8
Iversen, P.L.9
Bavari, S.10
-
101
-
-
84982234143
-
Therapeutic efficacy of the small molecule GS-5734 against Ebola virus in rhesus monkeys
-
Warren TK, Jordan R, Lo MK, Ray AS, Mackman RL, Soloveva V, Siegel D, Perron M, Bannister R, Hui HC, Larson N, Strickley R, Wells J, Stuthman KS, Van Tongeren SA, Garza NL, Donnelly G, Shurtleff AC, Retterer CJ, Gharaibeh D, Zamani R, Kenny T, Eaton BP, Grimes E, Welch LS, Gomba L, Wilhelmsen CL, Nichols DK, Nuss JE, Nagle ER, Kugelman JR, Palacios G, Doerffler E, Neville S, Carra E, Clarke MO, Zhang L, Lew W, Ross B, Wang Q, Chun K, Wolfe L, Babusis D, Park Y, Stray KM, Trancheva I, Feng JY, Barauskas O, Xu Y, Wong P, Braun MR, Flint M, McMullan LK, Chen SS, Fearns R, Swaminathan S, Mayers DL, Spiropoulou CF, Lee WA, Nichol ST, Cihlar T, Bavari S (2016) Therapeutic efficacy of the small molecule GS-5734 against Ebola virus in rhesus monkeys. Nature 531(7594):381–385. doi:10.1038/nature17180.
-
(2016)
Nature
, vol.531
, Issue.7594
, pp. 381-385
-
-
Warren, T.K.1
Jordan, R.2
Lo, M.K.3
Ray, A.S.4
Mackman, R.L.5
Soloveva, V.6
Siegel, D.7
Perron, M.8
Bannister, R.9
Hui, H.C.10
Larson, N.11
Strickley, R.12
Wells, J.13
Stuthman, K.S.14
Van Tongeren, S.A.15
Garza, N.L.16
Donnelly, G.17
Shurtleff, A.C.18
Retterer, C.J.19
Gharaibeh, D.20
Zamani, R.21
Kenny, T.22
Eaton, B.P.23
Grimes, E.24
Welch, L.S.25
Gomba, L.26
Wilhelmsen, C.L.27
Nichols, D.K.28
Nuss, J.E.29
Nagle, E.R.30
Kugelman, J.R.31
Palacios, G.32
Doerffler, E.33
Neville, S.34
Carra, E.35
Clarke, M.O.36
Zhang, L.37
Lew, W.38
Ross, B.39
Wang, Q.40
Chun, K.41
Wolfe, L.42
Babusis, D.43
Park, Y.44
Stray, K.M.45
Trancheva, I.46
Feng, J.Y.47
Barauskas, O.48
Xu, Y.49
Wong, P.50
Braun, M.R.51
Flint, M.52
McMullan, L.K.53
Chen, S.S.54
Fearns, R.55
Swaminathan, S.56
Mayers, D.L.57
Spiropoulou, C.F.58
Lee, W.A.59
Nichol, S.T.60
Cihlar, T.61
Bavari, S.62
more..
-
102
-
-
77956436149
-
Advanced antisense therapies for postexposure protection against lethal filovirus infections
-
Warren TK, Warfield KL, Wells J, Swenson DL, Donner KS, Van Tongeren SA, Garza NL, Dong L, Mourich DV, Crumley S, Nichols DK, Iversen PL, Bavari S (2010) Advanced antisense therapies for postexposure protection against lethal filovirus infections. Nat Med 16(9):991–994. doi:10.1038/nm.2202.
-
(2010)
Nat Med
, vol.16
, Issue.9
, pp. 991-994
-
-
Warren, T.K.1
Warfield, K.L.2
Wells, J.3
Swenson, D.L.4
Donner, K.S.5
Van Tongeren, S.A.6
Garza, N.L.7
Dong, L.8
Mourich, D.V.9
Crumley, S.10
Nichols, D.K.11
Iversen, P.L.12
Bavari, S.13
-
103
-
-
84899439262
-
Protection against filovirus diseases by a novel broad-spectrum nucleoside analogue BCX4430
-
Warren TK, Wells J, Panchal RG, Stuthman KS, Garza NL, Van Tongeren SA, Dong L, Retterer CJ, Eaton BP, Pegoraro G, Honnold S, Bantia S, Kotian P, Chen X, Taubenheim BR, Welch LS, Minning DM, Babu YS, Sheridan WP, Bavari S (2014) Protection against filovirus diseases by a novel broad-spectrum nucleoside analogue BCX4430. Nature 508(7496):402–405. doi:10.1038/nature13027.
-
(2014)
Nature
, vol.508
, Issue.7496
, pp. 402-405
-
-
Warren, T.K.1
Wells, J.2
Panchal, R.G.3
Stuthman, K.S.4
Garza, N.L.5
Van Tongeren, S.A.6
Dong, L.7
Retterer, C.J.8
Eaton, B.P.9
Pegoraro, G.10
Honnold, S.11
Bantia, S.12
Kotian, P.13
Chen, X.14
Taubenheim, B.R.15
Welch, L.S.16
Minning, D.M.17
Babu, Y.S.18
Sheridan, W.P.19
Bavari, S.20
more..
-
104
-
-
84988696751
-
A “Trojan horse” bispecific-antibody strategy for broad protection against ebolaviruses
-
Wec AZ, Nyakatura EK, Herbert AS, Howell KA, Holtsberg FW, Bakken RR, Mittler E, Christin JR, Shulenin S, Jangra RK, Bharrhan S, Kuehne AI, Bornholdt ZA, Flyak AI, Saphire EO, Crowe JE Jr, Aman MJ, Dye JM, Lai JR, Chandran K (2016) A “Trojan horse” bispecific-antibody strategy for broad protection against ebolaviruses. Science 354(6310):350–354. doi:10.1126/science.aag3267.
-
(2016)
Science
, vol.354
, Issue.6310
, pp. 350-354
-
-
Wec, A.Z.1
Nyakatura, E.K.2
Herbert, A.S.3
Howell, K.A.4
Holtsberg, F.W.5
Bakken, R.R.6
Mittler, E.7
Christin, J.R.8
Shulenin, S.9
Jangra, R.K.10
Bharrhan, S.11
Kuehne, A.I.12
Bornholdt, Z.A.13
Flyak, A.I.14
Saphire, E.O.15
Crowe, J.E.16
Aman, M.J.17
Dye, J.M.18
Lai, J.R.19
Chandran, K.20
more..
-
105
-
-
84990986145
-
Pathogenicity Comparison Between the Kikwit and Makona Ebola Virus Variants in Rhesus Macaques
-
Wong G, Qiu X, de La Vega MA, Fernando L, Wei H, Bello A, Fausther-Bovendo H, Audet J, Kroeker A, Kozak R, Tran K, He S, Tierney K, Soule G, Moffat E, Gunther S, Gao GF, Strong J, Embury-Hyatt C, Kobinger G (2016) Pathogenicity Comparison Between the Kikwit and Makona Ebola Virus Variants in Rhesus Macaques. J Infect Dis 214(Suppl 3):S281–S289. doi:10.1093/infdis/jiw267.
-
(2016)
J Infect Dis
, vol.214
, pp. S281-S289
-
-
Wong, G.1
Qiu, X.2
De La Vega, M.A.3
Fernando, L.4
Wei, H.5
Bello, A.6
Fausther-Bovendo, H.7
Audet, J.8
Kroeker, A.9
Kozak, R.10
Tran, K.11
He, S.12
Tierney, K.13
Soule, G.14
Moffat, E.15
Gunther, S.16
Gao, G.F.17
Strong, J.18
Embury-Hyatt, C.19
Kobinger, G.20
more..
-
106
-
-
84994097182
-
Epidemiologic characteristics, clinical manifestations, and risk factors of 139 patients with Ebola virus disease in western Sierra Leone
-
Xu Z, Jin B, Teng G, Rong Y, Sun L, Zhang J, Du N, Liu L, Su H, Yuan Y, Chen H (2016) Epidemiologic characteristics, clinical manifestations, and risk factors of 139 patients with Ebola virus disease in western Sierra Leone. Am J Infect Control 44(11), 1285–1290. doi:10.1016/j.ajic.2016.04.216.
-
(2016)
Am J Infect Control
, vol.44
, Issue.11
, pp. 1285-1290
-
-
Xu, Z.1
Jin, B.2
Teng, G.3
Rong, Y.4
Sun, L.5
Zhang, J.6
Du, N.7
Liu, L.8
Su, H.9
Yuan, Y.10
Chen, H.11
-
107
-
-
84975796039
-
Current and novel antiviral strategies for influenza infection
-
Yen HL (2016) Current and novel antiviral strategies for influenza infection. Curr Opin Virol 18:126–134. doi:10.1016/j.coviro.2016.05.004.
-
(2016)
Curr Opin Virol
, vol.18
, pp. 126-134
-
-
Yen, H.L.1
-
108
-
-
84978437369
-
Toremifene interacts with and destabilizes the Ebola virus glycoprotein
-
Zhao Y, Ren J, Harlos K, Jones DM, Zeltina A, Bowden TA, Padilla-Parra S, Fry EE, Stuart DI (2016) Toremifene interacts with and destabilizes the Ebola virus glycoprotein. Nature 535(7610):169–172. doi:10.1038/nature18615.
-
(2016)
Nature
, vol.535
, Issue.7610
, pp. 169-172
-
-
Zhao, Y.1
Ren, J.2
Harlos, K.3
Jones, D.M.4
Zeltina, A.5
Bowden, T.A.6
Padilla-Parra, S.7
Fry, E.E.8
Stuart, D.I.9
-
109
-
-
84923219776
-
Protease inhibitors targeting coronavirus and filovirus entry
-
Zhou Y, Vedantham P, Lu K, Agudelo J, Carrion R Jr, Nunneley JW, Barnard D, Pohlmann S, McKerrow JH, Renslo AR, Simmons G (2015) Protease inhibitors targeting coronavirus and filovirus entry. Antiviral Res 116:76–84. doi:10.1016/j.antiviral.2015.01.011.
-
(2015)
Antiviral Res
, vol.116
, pp. 76-84
-
-
Zhou, Y.1
Vedantham, P.2
Lu, K.3
Agudelo, J.4
Carrion, R.5
Nunneley, J.W.6
Barnard, D.7
Pohlmann, S.8
McKerrow, J.H.9
Renslo, A.R.10
Simmons, G.11
|