HIV-1 Vpr protein directly loads helicase-like transcription factor (HLTF) onto the CRL4-DCAF1 E3 ubiquitin ligase

Journal of Biological Chemistry

Volumn 292, Issue 51, 2017, Pages 21117-21127

  Zhou, Xiaohong ^a   Delucia, Maria ^a   Hao, Caili ^b   Hrecka, Kasia ^b   Monnie, Christina ^a   Skowronski, Jacek ^b   Ahn, Jinwoo ^a  

^a UNIVERSITY OF PITTSBURGH SCHOOL OF MEDICINE   (United States)

^b CASE WESTERN RESERVE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

DNA; TRANSCRIPTION; TRANSCRIPTION FACTORS;

DNA REPAIR PROTEINS; MOLECULAR MECHANISM; MUTATIONAL ANALYSIS; POLYUBIQUITINATION; PROTEASOMAL DEGRADATION; PROTEOMIC APPROACHES; RECONSTITUTION ASSAY; URACIL-DNA GLYCOSYLASE;

PROTEINS;

ADENOSINE TRIPHOSPHATASE; HELICASE LIKE TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR; UBIQUITIN PROTEIN LIGASE E3; UNCLASSIFIED DRUG; URACIL DNA GLYCOSIDASE; VPR PROTEIN; CARRIER PROTEIN; CRL4 PROTEIN, HUMAN; DNA BINDING PROTEIN; FLAG PEPTIDE; FUSION PROTEIN; HLTF PROTEIN, HUMAN; OLIGOPEPTIDE; PEPTIDE FRAGMENT; PROTEASOME; RECOMBINANT PROTEIN; UBIQUITIN PROTEIN LIGASE; VPR PROTEIN, HUMAN IMMUNODEFICIENCY VIRUS 1; VPRBP PROTEIN, HUMAN;

AMINO TERMINAL SEQUENCE; ARTICLE; CARBOXY TERMINAL SEQUENCE; CONTROLLED STUDY; DNA PROTEIN COMPLEX; DNA REPAIR; EMBRYO; GENE MUTATION; GENE TARGETING; HUMAN; HUMAN CELL; HUMAN IMMUNODEFICIENCY VIRUS 1; IN VITRO STUDY; MUTATIONAL ANALYSIS; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN DNA INTERACTION; PROTEIN DOMAIN; UBIQUITINATION; ANTAGONISTS AND INHIBITORS; BINDING SITE; CHEMISTRY; DIMERIZATION; GENE DELETION; GENETICS; HEK293 CELL LINE; METABOLISM; MOLECULAR MODEL; POINT MUTATION; PROTEIN MULTIMERIZATION; RNA INTERFERENCE; TUMOR CELL LINE; WD REPEAT;

BINDING SITES; CARRIER PROTEINS; CELL LINE, TUMOR; DIMERIZATION; DNA-BINDING PROTEINS; GENE DELETION; HEK293 CELLS; HUMANS; MODELS, MOLECULAR; OLIGOPEPTIDES; PEPTIDE FRAGMENTS; POINT MUTATION; PROTEASOME ENDOPEPTIDASE COMPLEX; PROTEIN INTERACTION DOMAINS AND MOTIFS; PROTEIN MULTIMERIZATION; RECOMBINANT FUSION PROTEINS; RECOMBINANT PROTEINS; RNA INTERFERENCE; TRANSCRIPTION FACTORS; UBIQUITIN-PROTEIN LIGASES; UBIQUITINATION; VPR GENE PRODUCTS, HUMAN IMMUNODEFICIENCY VIRUS; WD40 REPEATS;

EID: 85039432245     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M117.798801     Document Type: Article

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