Intranasal insulin treatment restores cognitive deficits and insulin signaling impairment induced by repeated methamphetamine exposure

Journal of Cellular Biochemistry

Volumn 119, Issue 2, 2018, Pages 2345-2355

  Beirami, Elmira ^a   Oryan, Shahrbanoo ^a   Seyedhosseini Tamijani, Seyedeh Masoumeh ^b   Ahmadiani, Abolhassan ^b   Dargahi, Leila ^b  

^a KHARAZMI UNIVERSITY   (Iran)

^b SHAHID BEHESHTI UNIVERSITY OF MEDICAL SCIENCES   (Iran)

Author keywords

cognition; insulin; insulin signaling; methamphetamine; mitochondrial biogenesis

Indexed keywords

GLYCOGEN SYNTHASE KINASE 3BETA; INSULIN; INSULIN RECEPTOR; INSULIN RECEPTOR SUBSTRATE; METHAMPHETAMINE; MITOCHONDRIAL TRANSCRIPTION FACTOR A; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA COACTIVATOR 1ALPHA; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN KINASE B; TRANSCRIPTION FACTOR NRF1;

ADULT; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; COGNITIVE DEFECT; CONTROLLED STUDY; DISORDERS OF MITOCHONDRIAL FUNCTIONS; DRUG DELIVERY SYSTEM; DRUG EFFICACY; HIPPOCAMPUS; INSULIN SIGNALING; INSULIN TREATMENT; MALE; MEMORY DISORDER; MITOCHONDRIAL BIOGENESIS; NONHUMAN; NOVEL OBJECT RECOGNITION TEST; PASSIVE AVOIDANCE TEST; PRIORITY JOURNAL; RAT; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; WESTERN BLOTTING; Y-MAZE TEST; AMPHETAMINE DEPENDENCE; ANIMAL; CHEMICALLY INDUCED; COMPLICATION; DISEASE MODEL; DRUG EFFECT; GENE EXPRESSION REGULATION; GENE REGULATORY NETWORK; GENETICS; INTRANASAL DRUG ADMINISTRATION; METABOLISM; MITOCHONDRION; SHORT TERM MEMORY; SIGNAL TRANSDUCTION; WISTAR RAT;

ADMINISTRATION, INTRANASAL; AMPHETAMINE-RELATED DISORDERS; ANIMALS; COGNITION DISORDERS; DISEASE MODELS, ANIMAL; GENE EXPRESSION REGULATION; GENE REGULATORY NETWORKS; INSULIN; MALE; MEMORY, SHORT-TERM; METHAMPHETAMINE; MITOCHONDRIA; RATS; RATS, WISTAR; SIGNAL TRANSDUCTION;

EID: 85038812573     PISSN: 07302312     EISSN: 10974644     Source Type: Journal    
DOI: 10.1002/jcb.26398     Document Type: Article

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