메뉴 건너뛰기




Volumn 131, Issue 5, 2014, Pages 582-587

Insulin induces phosphorylation of the AMPA receptor subunit GluR1, reversed by ZIP, and over-expression of protein kinase M zeta, reversed by amyloid beta

Author keywords

Alzheimer; AMPA; A ; Insulin; PKM ; ZIP

Indexed keywords

AMPA RECEPTOR; AMYLOID BETA PROTEIN; AMYLOID BETA PROTEIN[1-42]; CELL PROTEIN; GLUTAMATE RECEPTOR 1; INSULIN; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; OLIGOMER; PROTEIN KINASE M ZETA; UNCLASSIFIED DRUG; ZETA INHIBITORY PEPTIDE; 3 BROMO 5 TERT BUTYL 4 HYDROXYBENZYLIDENEMALONONITRILE; AMYLOID BETA-PROTEIN (1-42); ANTIDIABETIC AGENT; GLUTAMATE RECEPTOR IONOTROPIC, AMPA 1; PEPTIDE FRAGMENT; PROTEIN KINASE C; PROTEIN KINASE C ZETA; REPRESSOR PROTEIN; SERINE; TYRPHOSTIN;

EID: 84915775796     PISSN: 00223042     EISSN: 14714159     Source Type: Journal    
DOI: 10.1111/jnc.12947     Document Type: Article
Times cited : (32)

References (49)
  • 1
    • 0033197996 scopus 로고    scopus 로고
    • The insulin receptor tyrosine kinase susbstrate p58/53 and the insulin receptor are components of CNS synapses
    • Abbott M. A., Wells D. G. and Fallon J. R. (1999) The insulin receptor tyrosine kinase susbstrate p58/53 and the insulin receptor are components of CNS synapses. J. Neurosci. 19, 7300-7308.
    • (1999) J. Neurosci. , vol.19 , pp. 7300-7308
    • Abbott, M.A.1    Wells, D.G.2    Fallon, J.R.3
  • 2
    • 12144288368 scopus 로고    scopus 로고
    • Tyrosine phosphorylation of GluR2 is required for insulin -stimulated AMPA receptor endocytosis and LTD
    • Ahmadian G., Ju W., Liu L. et al. (2004) Tyrosine phosphorylation of GluR2 is required for insulin -stimulated AMPA receptor endocytosis and LTD. EMBO J. 23, 1040-1050.
    • (2004) EMBO J. , vol.23 , pp. 1040-1050
    • Ahmadian, G.1    Ju, W.2    Liu, L.3
  • 3
    • 0031456345 scopus 로고    scopus 로고
    • Selective, physiological transport of insulin across the blood-brain barrier: Novel demonstration by species-specific radioimmunoassays
    • Banks W. A., Jaspan J. B. and Kastin A. J. (1997) Selective, physiological transport of insulin across the blood-brain barrier: novel demonstration by species-specific radioimmunoassays. Peptides 18, 1257-1262.
    • (1997) Peptides , vol.18 , pp. 1257-1262
    • Banks, W.A.1    Jaspan, J.B.2    Kastin, A.J.3
  • 4
    • 0030744875 scopus 로고    scopus 로고
    • Regulatory phosphorylation of AMPA-type glutamate receptors by CaM-KII during long-term potentiation
    • Barria A., Muller D., Derkach V., Griffith L. C. and Soderling T. R. (1997) Regulatory phosphorylation of AMPA-type glutamate receptors by CaM-KII during long-term potentiation. Science 276, 2042-2045.
    • (1997) Science , vol.276 , pp. 2042-2045
    • Barria, A.1    Muller, D.2    Derkach, V.3    Griffith, L.C.4    Soderling, T.R.5
  • 6
    • 33745927153 scopus 로고    scopus 로고
    • Synaptic incorporation of AMPA receptors during LTP is controlled by a PKC phosphorylation site on GluR1
    • Boehm J., Kang M. G., Johnson R. C., Esteban J., Huganir R. L. and Malinow R. (2006) Synaptic incorporation of AMPA receptors during LTP is controlled by a PKC phosphorylation site on GluR1. Neuron 51, 213-225.
    • (2006) Neuron , vol.51 , pp. 213-225
    • Boehm, J.1    Kang, M.G.2    Johnson, R.C.3    Esteban, J.4    Huganir, R.L.5    Malinow, R.6
  • 7
    • 0027226219 scopus 로고
    • Optimized survival of hippocampal neurons in B27-supplemented Neurobasal, a new serum-free medium combination
    • Brewer G. J., Torricelli J. R., Evege E. K. and Price P. J. (1993) Optimized survival of hippocampal neurons in B27-supplemented Neurobasal, a new serum-free medium combination. J. Neurosci. Res. 35, 567-576.
    • (1993) J. Neurosci. Res. , vol.35 , pp. 567-576
    • Brewer, G.J.1    Torricelli, J.R.2    Evege, E.K.3    Price, P.J.4
  • 8
    • 0031980737 scopus 로고    scopus 로고
    • Calcium influx through AMP A receptors and through calcium channels is regulated by protein kinase C in cultured retina amacrine-like cells
    • Carvalho A. L., Duarte C. B., Faro C. J., Carvalho A. P. and Pires E. V. (1998) Calcium influx through AMP A receptors and through calcium channels is regulated by protein kinase C in cultured retina amacrine-like cells. J. Neurochem. 70, 2112-2119.
    • (1998) J. Neurochem. , vol.70 , pp. 2112-2119
    • Carvalho, A.L.1    Duarte, C.B.2    Faro, C.J.3    Carvalho, A.P.4    Pires, E.V.5
  • 9
  • 10
    • 34147173277 scopus 로고    scopus 로고
    • Insulin resistance and Alzheimer's disease pathogenesis: Potential mechanisms and implications for treatment
    • Craft S. (2007) Insulin resistance and Alzheimer's disease pathogenesis: potential mechanisms and implications for treatment. Curr. Alzheimer Res. 4: 147-152.
    • (2007) Curr. Alzheimer Res. , vol.4 , pp. 147-152
    • Craft, S.1
  • 11
    • 84856797277 scopus 로고    scopus 로고
    • Activation of PKCzeta and PKMzeta in the nucleus accumbens core is necessary for the retrieval, consolidation and reconsolidation of drug memory
    • Crespo J. A., Stöckl P., Ueberall F., Jenny M., Saria A. and Zernig G. (2012) Activation of PKCzeta and PKMzeta in the nucleus accumbens core is necessary for the retrieval, consolidation and reconsolidation of drug memory. PLoS ONE 7, e30502.
    • (2012) PLoS ONE , vol.7 , pp. e30502
    • Crespo, J.A.1    Stöckl, P.2    Ueberall, F.3    Jenny, M.4    Saria, A.5    Zernig, G.6
  • 13
    • 28844495644 scopus 로고    scopus 로고
    • Insulin receptor signaling in long-term memory consolidation following spatial learning
    • Dou J. T., Chen M., Dufour F., Alkon D. L. and Zhao W. Q. (2005) Insulin receptor signaling in long-term memory consolidation following spatial learning. Learn. Mem. 12, 646-655.
    • (2005) Learn. Mem. , vol.12 , pp. 646-655
    • Dou, J.T.1    Chen, M.2    Dufour, F.3    Alkon, D.L.4    Zhao, W.Q.5
  • 14
    • 0018090354 scopus 로고
    • Insulin receptors are widely distributed in the central nervous system of the rat
    • Havrankova J., Roth J. and Brownstein M. (1978) Insulin receptors are widely distributed in the central nervous system of the rat. Nature 272, 827-829.
    • (1978) Nature , vol.272 , pp. 827-829
    • Havrankova, J.1    Roth, J.2    Brownstein, M.3
  • 15
    • 0141890287 scopus 로고    scopus 로고
    • Protein Kinase Mzeta synthesis from a brain mRNA encoding an independent protein kinase C zeta catalytic domain. Implications for the molecular mechanism of memory
    • Hernandez A. I., Blace N., Crary J. F., Serrano P. A., Leitges M., Libien J. M., Weinstein G., Tcherapanov A. and Sacktor T. C. (2003) Protein Kinase Mzeta synthesis from a brain mRNA encoding an independent protein kinase C zeta catalytic domain. Implications for the molecular mechanism of memory. J. Biol. Chem. 278, 40305-40316.
    • (2003) J. Biol. Chem. , vol.278 , pp. 40305-40316
    • Hernandez, A.I.1    Blace, N.2    Crary, J.F.3    Serrano, P.A.4    Leitges, M.5    Libien, J.M.6    Weinstein, G.7    Tcherapanov, A.8    Sacktor, T.C.9
  • 16
    • 1842562359 scopus 로고    scopus 로고
    • An investigation into signal transduction mechanisms involved in insulin-induced longterm depression in the CA1 region of the hippocampus
    • Huang C. C., Lee C. C. and Hsu K. S. (2004) An investigation into signal transduction mechanisms involved in insulin-induced longterm depression in the CA1 region of the hippocampus. J. Neurochem. 89, 217-231.
    • (2004) J. Neurochem. , vol.89 , pp. 217-231
    • Huang, C.C.1    Lee, C.C.2    Hsu, K.S.3
  • 17
    • 34047168248 scopus 로고    scopus 로고
    • Regulation of protein kinase Mzeta synthesis by multiple kinases in long-term potentiation
    • Kelly M. T., Crary J. F. and Sacktor T. C. (2007) Regulation of protein kinase Mzeta synthesis by multiple kinases in long-term potentiation. J. Neurosci. 27, 3439-3444.
    • (2007) J. Neurosci. , vol.27 , pp. 3439-3444
    • Kelly, M.T.1    Crary, J.F.2    Sacktor, T.C.3
  • 18
    • 0027170453 scopus 로고
    • Mechanism of protein kinase C activation during the induction and maintenance of longterm potentiation probed using a selective peptide substrate
    • Klann E., Chen S. J. and Sweatt J. D. (1993) Mechanism of protein kinase C activation during the induction and maintenance of longterm potentiation probed using a selective peptide substrate. Proc. Natl Acad. Sci. USA 90, 8337-8341.
    • (1993) Proc. Natl Acad. Sci. USA , vol.90 , pp. 8337-8341
    • Klann, E.1    Chen, S.J.2    Sweatt, J.D.3
  • 19
    • 0034702259 scopus 로고    scopus 로고
    • Regulation of distinct AMPA receptor phosphorylation sites during bidirectional synaptic plasticity
    • Lee H. K., Barbarosie M., Kameyama K., Bear M. F. and Huganir R. L. (2000) Regulation of distinct AMPA receptor phosphorylation sites during bidirectional synaptic plasticity. Nature 405, 955-959.
    • (2000) Nature , vol.405 , pp. 955-959
    • Lee, H.K.1    Barbarosie, M.2    Kameyama, K.3    Bear, M.F.4    Huganir, R.L.5
  • 20
    • 33745133729 scopus 로고    scopus 로고
    • Protein kinase Mzeta enhances excitatory synaptic transmission by increasing the number of active postsynaptic AMPA receptors
    • Ling D. S., Benardo L. S. and Sacktor T. C. (2006) Protein kinase Mzeta enhances excitatory synaptic transmission by increasing the number of active postsynaptic AMPA receptors. Hippocampus 16, 443-452.
    • (2006) Hippocampus , vol.16 , pp. 443-452
    • Ling, D.S.1    Benardo, L.S.2    Sacktor, T.C.3
  • 21
    • 84857233851 scopus 로고    scopus 로고
    • Memory erasure by very high concentrations of ZIP may not be due to PKM-zeta
    • Lisman J. (2012) Memory erasure by very high concentrations of ZIP may not be due to PKM-zeta. Hippocampus 22, 648-649.
    • (2012) Hippocampus , vol.22 , pp. 648-649
    • Lisman, J.1
  • 22
    • 0024461379 scopus 로고
    • Inhibition of postsynaptic PKC or CaMKII blocks induction but not expression of LTP
    • Malinow R., Schulman H. and Tsien R. W. (1989) Inhibition of postsynaptic PKC or CaMKII blocks induction but not expression of LTP. Science 245, 862-866.
    • (1989) Science , vol.245 , pp. 862-866
    • Malinow, R.1    Schulman, H.2    Tsien, R.W.3
  • 23
    • 0031435496 scopus 로고    scopus 로고
    • Phosphorylation of the α-amino-3-hydroxy-5-methylisoxazole-4-propionic acid receptor GluR1 by calcium/calmodulin-dependent kinase II
    • Mammen A. L., Kameyama K., Roche K. W. and Huganir R. L. (1997) Phosphorylation of the α-amino-3-hydroxy-5-methylisoxazole-4-propionic acid receptor GluR1 by calcium/calmodulin-dependent kinase II. J. Biol. Chem. 272, 32528-32533.
    • (1997) J. Biol. Chem. , vol.272 , pp. 32528-32533
    • Mammen, A.L.1    Kameyama, K.2    Roche, K.W.3    Huganir, R.L.4
  • 24
    • 0033681557 scopus 로고    scopus 로고
    • Regulation of AMPA receptormediated synaptic transmission by clathrin-dependent receptor internalization
    • Man H. Y., Lin J. W., Ju W. H., Ahmadian G., Liu L., Becker L. E., Sheng M. and Wang Y. T. (2000) Regulation of AMPA receptormediated synaptic transmission by clathrin-dependent receptor internalization. Neuron 25, 649-662.
    • (2000) Neuron , vol.25 , pp. 649-662
    • Man, H.Y.1    Lin, J.W.2    Ju, W.H.3    Ahmadian, G.4    Liu, L.5    Becker, L.E.6    Sheng, M.7    Wang, Y.T.8
  • 25
    • 80355125164 scopus 로고    scopus 로고
    • Specific involvement of atypical PKCξ/PKMξ in spinal persistent nociceptive processing following peripheral inflammation in rat
    • Marchand F., D'Mello R., Yip P. K., Calvo M., Muller E., Pezet S., Dickenson A. H. and McMahon S. B. (2011) Specific involvement of atypical PKCf/PKMζ in spinal persistent nociceptive processing following peripheral inflammation in rat. Mol. Pain 7, 86.
    • (2011) Mol. Pain , vol.7 , pp. 86
    • Marchand, F.1    D'Mello, R.2    Yip, P.K.3    Calvo, M.4    Muller, E.5    Pezet, S.6    Dickenson, A.H.7    McMahon, S.B.8
  • 26
    • 41549089757 scopus 로고    scopus 로고
    • Receptor for advanced glycation end product-dependent activation of p38 mitogenactivated protein kinase contributes to amyloid-beta-mediated cortical synaptic dysfunction
    • Origlia N., Righi M., Capsoni S. et al. (2008) Receptor for advanced glycation end product-dependent activation of p38 mitogenactivated protein kinase contributes to amyloid-beta-mediated cortical synaptic dysfunction. J. Neurosci. 28, 3521-3530.
    • (2008) J. Neurosci. , vol.28 , pp. 3521-3530
    • Origlia, N.1    Righi, M.2    Capsoni, S.3
  • 27
    • 67650882249 scopus 로고    scopus 로고
    • Abeta-dependent Inhibition of LTP in different intracortical circuits of the visual cortex: The role of RAGE
    • Origlia N., Capsoni S., Cattaneo A., Fang F., Arancio O., Yan S. D. and Domenici L. (2009) Abeta-dependent Inhibition of LTP in different intracortical circuits of the visual cortex: the role of RAGE. J. Alzheimers Dis. 17, 59-68.
    • (2009) J. Alzheimers Dis. , vol.17 , pp. 59-68
    • Origlia, N.1    Capsoni, S.2    Cattaneo, A.3    Fang, F.4    Arancio, O.5    Yan, S.D.6    Domenici, L.7
  • 28
    • 0034869177 scopus 로고    scopus 로고
    • Subunit-specific temporal and spatial patterns of AMPA receptor exocytosis in hippocampal neurons
    • Passafaro M., Piech V. and Sheng M. (2001) Subunit-specific temporal and spatial patterns of AMPA receptor exocytosis in hippocampal neurons. Nat. Neurosci. 4, 917-926.
    • (2001) Nat. Neurosci. , vol.4 , pp. 917-926
    • Passafaro, M.1    Piech, V.2    Sheng, M.3
  • 30
    • 47849123972 scopus 로고    scopus 로고
    • Intranasal insulin administration dose-dependently modulates verbal memory and plasma amyloid-beta in memory-impaired older adults
    • Reger M. A., Watson G. S., Green P. S. et al. (2008) Intranasal insulin administration dose-dependently modulates verbal memory and plasma amyloid-beta in memory-impaired older adults. J. Alzheimers Dis. 13, 323-331.
    • (2008) J. Alzheimers Dis. , vol.13 , pp. 323-331
    • Reger, M.A.1    Watson, G.S.2    Green, P.S.3
  • 31
    • 0030175899 scopus 로고    scopus 로고
    • Characterization of multiple phosphorylation sites on the AMPA receptor GluR1 subunit
    • Roche K. W., O'Brien R. J., Mammen A. L., Bernhardt J. and Huganir R. L. (1996) Characterization of multiple phosphorylation sites on the AMPA receptor GluR1 subunit. Neuron 16, 1179-1188.
    • (1996) Neuron , vol.16 , pp. 1179-1188
    • Roche, K.W.1    O'Brien, R.J.2    Mammen, A.L.3    Bernhardt, J.4    Huganir, R.L.5
  • 32
    • 41349089303 scopus 로고    scopus 로고
    • PKMzeta, LTP maintenance, and the dynamic molecular biology of memory storage
    • Sacktor T. C. (2008) PKMzeta, LTP maintenance, and the dynamic molecular biology of memory storage. Prog. Brain Res. 169, 27-40.
    • (2008) Prog. Brain Res. , vol.169 , pp. 27-40
    • Sacktor, T.C.1
  • 33
    • 0037174618 scopus 로고    scopus 로고
    • Alzheimer's disease is a synaptic failure
    • Selkoe D. J. (2002) Alzheimer's disease is a synaptic failure. Science 298, 789-791.
    • (2002) Science , vol.298 , pp. 789-791
    • Selkoe, D.J.1
  • 34
    • 0035853124 scopus 로고    scopus 로고
    • Insulin promotes rapid delivery of N-methyl-D-aspartate receptors to the cell surface by exocytosis
    • Skeberdis V. A., Lan J., Zheng X., Zukin R. S. and Bennett M. V. (2001) Insulin promotes rapid delivery of N-methyl-D-aspartate receptors to the cell surface by exocytosis. Proc. Natl Acad. Sci. USA 98, 3561-3566.
    • (2001) Proc. Natl Acad. Sci. USA , vol.98 , pp. 3561-3566
    • Skeberdis, V.A.1    Lan, J.2    Zheng, X.3    Zukin, R.S.4    Bennett, M.V.5
  • 36
    • 36348935683 scopus 로고    scopus 로고
    • Soluble Abeta inhibits specific signal transduction cascades common to the insulin receptor pathway
    • Townsend M., Mehta T. and Selkoe D. J. (2007) Soluble Abeta inhibits specific signal transduction cascades common to the insulin receptor pathway. J. Biol. Chem. 282, 33305-33312.
    • (2007) J. Biol. Chem. , vol.282 , pp. 33305-33312
    • Townsend, M.1    Mehta, T.2    Selkoe, D.J.3
  • 38
    • 33749174297 scopus 로고    scopus 로고
    • Proinsulin/insulin is synthesized locally and prevents caspase- and cathepsin-mediated cell death in the embryonic mouse retina
    • Valenciano A. I., Corrochano S., de Pablo F., de la Villa P. and de la Rosa E. J. (2006) Proinsulin/insulin is synthesized locally and prevents caspase- and cathepsin-mediated cell death in the embryonic mouse retina. J. Neurochem. 99, 524-536.
    • (2006) J. Neurochem. , vol.99 , pp. 524-536
    • Valenciano, A.I.1    Corrochano, S.2    De Pablo, F.3    De La-Villa, P.4    De La-Rosa, E.J.5
  • 39
    • 84872611798 scopus 로고    scopus 로고
    • PKM-ξ is not required for hippocampal synaptic plasticity, learning and memory
    • Volk L. J., Bachman J. L., Johnson R., Yu Y. and Huganir R. L. (2013) PKM-ξ is not required for hippocampal synaptic plasticity, learning and memory. Nature 493, 420-423.
    • (2013) Nature , vol.493 , pp. 420-423
    • Volk, L.J.1    Bachman, J.L.2    Johnson, R.3    Yu, Y.4    Huganir, R.L.5
  • 41
    • 0026546647 scopus 로고
    • Postsynaptic protein kinase C essential to induction and maintenance of long-term potentiation in the hippocampal CA1 region
    • Wang J. H. and Feng D. P. (1992) Postsynaptic protein kinase C essential to induction and maintenance of long-term potentiation in the hippocampal CA1 region. Proc. Natl Acad. Sci. USA 89, 2576-2580.
    • (1992) Proc. Natl Acad. Sci. USA , vol.89 , pp. 2576-2580
    • Wang, J.H.1    Feng, D.P.2
  • 42
    • 0028204241 scopus 로고
    • Modulation of AMPA/kainate receptors in cultured murine hippocampal neurones by protein kinase C
    • Wang L. Y., Dudek E. M., Browning M. D. and MacDonald J. F. (1994) Modulation of AMPA/kainate receptors in cultured murine hippocampal neurones by protein kinase C. J. Physiol. 475, 431-437.
    • (1994) J. Physiol. , vol.475 , pp. 431-437
    • Wang, L.Y.1    Dudek, E.M.2    Browning, M.D.3    MacDonald, J.F.4
  • 43
    • 0036710280 scopus 로고    scopus 로고
    • IRS proteins and the common path to diabetes
    • White M. F. (2002) IRS proteins and the common path to diabetes. Am. J. Physiol. Endocrinol. Metab. 283, 413-422.
    • (2002) Am. J. Physiol. Endocrinol. Metab. , vol.283 , pp. 413-422
    • White, M.F.1
  • 44
    • 33748060215 scopus 로고    scopus 로고
    • Learning induces long-term potentiation in the hippocampus
    • Whitlock J. R., Heynen A. J., Shuler M. G. and Bear M. F. (2006) Learning induces long-term potentiation in the hippocampus. Science 313, 1093-1097.
    • (2006) Science , vol.313 , pp. 1093-1097
    • Whitlock, J.R.1    Heynen, A.J.2    Shuler, M.G.3    Bear, M.F.4
  • 47
    • 50349090751 scopus 로고    scopus 로고
    • PKM zeta maintains late longterm potentiation by N-ethylmaleimide-sensitive factor/GluR2-dependent trafficking of postsynaptic AMPA receptors
    • Yao Y., Kelly M. T., Sajikumar S., Serrano P., Tian D., Bergold P. J., Frey J. U. and Sacktor T. C. (2008) PKM zeta maintains late longterm potentiation by N-ethylmaleimide-sensitive factor/GluR2-dependent trafficking of postsynaptic AMPA receptors. J. Neurosci. 28, 7820-7827.
    • (2008) J. Neurosci. , vol.28 , pp. 7820-7827
    • Yao, Y.1    Kelly, M.T.2    Sajikumar, S.3    Serrano, P.4    Tian, D.5    Bergold, P.J.6    Frey, J.U.7    Sacktor, T.C.8
  • 48
    • 0033521130 scopus 로고    scopus 로고
    • Brain insulin receptors and spatial memory. Correlated changes in gene expression, tyrosine phosphorylation, and signaling molecules in the hippocampus of water maze trained rats
    • Zhao W., Chen H., Xu H., Moore E., Meiri N., Quon M. J. and Alkon D. L. (1999) Brain insulin receptors and spatial memory. Correlated changes in gene expression, tyrosine phosphorylation, and signaling molecules in the hippocampus of water maze trained rats. J. Biol. Chem. 274, 34893-34902.
    • (1999) J. Biol. Chem. , vol.274 , pp. 34893-34902
    • Zhao, W.1    Chen, H.2    Xu, H.3    Moore, E.4    Meiri, N.5    Quon, M.J.6    Alkon, D.L.7


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.