Independently Tuning the Biochemical and Mechanical Properties of 3D Hyaluronan-Based Hydrogels with Oxime and Diels-Alder Chemistry to Culture Breast Cancer Spheroids

Biomacromolecules

Volumn 18, Issue 12, 2017, Pages 4373-4384

  Baker, Alexander E G ^a,b   Tam, Roger Y ^a   Shoichet, Molly S ^a,b  

^a UNIVERSITY OF TORONTO   (Canada)

^b UNIVERSITY OF TORONTO   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

BIOMECHANICS; BIOMIMETICS; CELL CULTURE; CELLS; CONTROLLED DRUG DELIVERY; CROSSLINKING; DIAGNOSIS; DISEASES; FUNCTIONAL GROUPS; GRAFTING (CHEMICAL); HYDROGELS; MECHANICAL PROPERTIES; PEPTIDES; TUMORS;

3-D CELL CULTURE; BIOACTIVE PEPTIDES; BIOCHEMICAL PROPERTIES; BREAST CANCER CELLS; CHEMICAL CROSS-LINKING; CHEMICALLY MODIFIED; MULTIDRUG RESISTANTS; TUMOR MICROENVIRONMENT;

HYALURONIC ACID;

ALDEHYDE; DOXORUBICIN; HYALURONIC ACID; MACROGOL; MATRIGEL; OXIME; BIOMIMETIC MATERIAL; COLLAGEN; LAMININ; PROTEOGLYCAN;

ARTICLE; BREAST CANCER; CONTROLLED STUDY; DIELS ALDER REACTION; EXTRACELLULAR MATRIX; HYDROGEL; POLYMERIZATION; PRIORITY JOURNAL; PROTON NUCLEAR MAGNETIC RESONANCE; SYNTHESIS; TUMOR MICROENVIRONMENT; TUMOR SPHEROID; UPREGULATION; BREAST TUMOR; CELL CULTURE TECHNIQUE; CELL PROLIFERATION; CHEMISTRY; DRUG COMBINATION; FEMALE; HUMAN; MCF-7 CELL LINE; MULTICELLULAR SPHEROID; PATHOLOGY; PHYSIOLOGY; PROCEDURES; TUMOR CELL LINE;

BIOMIMETIC MATERIALS; BREAST NEOPLASMS; CELL CULTURE TECHNIQUES; CELL LINE, TUMOR; CELL PROLIFERATION; COLLAGEN; DRUG COMBINATIONS; FEMALE; HUMANS; HYALURONIC ACID; HYDROGELS; LAMININ; MCF-7 CELLS; OXIMES; PROTEOGLYCANS; SPHEROIDS, CELLULAR; TUMOR MICROENVIRONMENT;

EID: 85038216133     PISSN: 15257797     EISSN: 15264602     Source Type: Journal    
DOI: 10.1021/acs.biomac.7b01422     Document Type: Article

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