Network-based approaches that exploit inferred transcription factor activity to analyze the impact of genetic variation on gene expression

Current Opinion in Systems Biology

Volumn 2, Issue , 2017, Pages 98-102

  Bussemaker, Harmen J ^a   Causton, Helen C ^b   Fazlollahi, Mina ^c   Lee, Eunjee ^c   Muroff, Ivor ^a  

^a Howard Hughes Medical Institute   (United States)

^b New York Presbyterian Morgan Stanley Children's Hospital   (United States)

^c MOUNT SINAI SCHOOL OF MEDICINE   (United States)

Author keywords

AQTL; CQTL; Gene regulatory networks; QTL mapping; Systems genetics; Transcription factor activity

Indexed keywords

TRANSCRIPTION FACTOR;

BINDING AFFINITY; BINDING SITE; DNA BINDING; GENE EXPRESSION; GENE REGULATORY NETWORK; GENETIC TRAIT; GENETIC VARIATION; HUMAN; PROMOTER REGION; PROTEIN FUNCTION; REGULON; REVIEW; TRANSACTIVATION; TRANSCRIPTION REGULATION;

EID: 85038103721     PISSN: None     EISSN: 24523100     Source Type: Journal    
DOI: 10.1016/j.coisb.2017.04.002     Document Type: Review

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