Sodium butyrate triggers a functional elongation of microglial process via Akt-small RhoGTPase activation and HDACs inhibition

Neurobiology of Disease

Volumn 111, Issue , 2018, Pages 12-25

  Wang, Peng ^a   Zhang, Yaru ^a   Gong, Yu ^a   Yang, Rongrong ^a   Chen, Zhuo ^a   Hu, Wenfeng ^a   Wu, Yue ^a   Gao, Minhui ^a   Xu, Xing ^a   Qin, Yibin ^a   Huang, Chao ^a  

^a NANTONG UNIVERSITY   (China)

Author keywords

Microglia; Neuroinflammation; Process elongation; Protein kinase B; Small RhoGTPase; Sodium butyrate

Indexed keywords

BUTYRIC ACID; HISTONE DEACETYLASE; INTERLEUKIN 10; INTERLEUKIN 1BETA; MESSENGER RNA; PROTEIN CDC42; PROTEIN KINASE B; RAC1 PROTEIN; RHO GUANINE NUCLEOTIDE BINDING PROTEIN; TRICHOSTATIN A; TUMOR NECROSIS FACTOR; VALPROIC ACID; ANTIHISTAMINIC AGENT; GUANOSINE TRIPHOSPHATASE; LIPOPOLYSACCHARIDE; NONSTEROID ANTIINFLAMMATORY AGENT;

ANIMAL CELL; ANIMAL EXPERIMENT; ANTIINFLAMMATORY ACTIVITY; ARTICLE; CONTROLLED STUDY; FORCED SWIM TEST; IN VITRO STUDY; IN VIVO STUDY; MALE; MICROGLIA; MOUSE; NERVOUS SYSTEM INFLAMMATION; NEWBORN; NONHUMAN; PREFRONTAL CORTEX; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; SUCROSE PREFERENCE TEST; TAIL SUSPENSION TEST; ANIMAL; C57BL MOUSE; CELL CULTURE; CELL ENLARGEMENT; DRUG EFFECT; ENZYMOLOGY; IMMUNOLOGY; INFLAMMATION; METABOLISM; PATHOLOGY;

ANIMALS; ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL; BUTYRIC ACID; CELL ENLARGEMENT; CELLS, CULTURED; GTP PHOSPHOHYDROLASES; HISTAMINE ANTAGONISTS; HISTONE DEACETYLASES; INFLAMMATION; LIPOPOLYSACCHARIDES; MALE; MICE, INBRED C57BL; MICROGLIA; PREFRONTAL CORTEX; PROTO-ONCOGENE PROTEINS C-AKT;

EID: 85038026182     PISSN: 09699961     EISSN: 1095953X     Source Type: Journal    
DOI: 10.1016/j.nbd.2017.12.006     Document Type: Article

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