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Volumn 13, Issue 3, 2015, Pages 239-244

The gut-brain axis: The missing link in depression

Author keywords

Depression; Microbiota; Probiotics

Indexed keywords

ACTIVATED CARBON; PROBIOTIC AGENT;

EID: 84949423767     PISSN: 17381088     EISSN: 20934327     Source Type: Journal    
DOI: 10.9758/cpn.2015.13.3.239     Document Type: Review
Times cited : (242)

References (74)
  • 1
    • 84893144938 scopus 로고    scopus 로고
    • A clinician's primer on the role of the microbiome in human health and disease
    • Khanna S, Tosh PK. A clinician's primer on the role of the microbiome in human health and disease. Mayo Clin Proc 2014;89:107-114.
    • (2014) Mayo Clin Proc , vol.89 , pp. 107-114
    • Khanna, S.1    Tosh, P.K.2
  • 3
    • 84864754089 scopus 로고    scopus 로고
    • Role of the intestinal microbiome in health and disease: From correlation to causation
    • de Vos WM, de Vos EA. Role of the intestinal microbiome in health and disease: from correlation to causation. Nutr Rev 2012;70 Suppl 1:S45-S56.
    • (2012) Nutr Rev , vol.70 , pp. S45-S56
    • De Vos, W.M.1    De Vos, E.A.2
  • 5
    • 84862192626 scopus 로고    scopus 로고
    • Evaluation of 16S rDNA-based community profiling for human microbiome research
    • Jumpstart Consortium Human Microbiome Project Data Generation Working Group
    • Jumpstart Consortium Human Microbiome Project Data Generation Working Group. Evaluation of 16S rDNA-based community profiling for human microbiome research. PLoS One 2012;7:e39315.
    • (2012) PLoS One , vol.7 , pp. e39315
  • 6
    • 84922013593 scopus 로고    scopus 로고
    • Gut-brain link grabs neuroscientists
    • Reardon S. Gut-brain link grabs neuroscientists. Nature 2014;515:175-177.
    • (2014) Nature , vol.515 , pp. 175-177
    • Reardon, S.1
  • 7
    • 84864752706 scopus 로고    scopus 로고
    • The impact of nutrition on the human microbiome
    • Flint HJ. The impact of nutrition on the human microbiome. Nutr Rev 2012;70 Suppl 1:S10-S13.
    • (2012) Nutr Rev , vol.70 , pp. S10-S13
    • Flint, H.J.1
  • 8
    • 84873570579 scopus 로고    scopus 로고
    • American Journal of Gastroenterology Lecture: Intestinal microbiota and the role of fecal microbiota transplant (FMT) in treatment of C. Difficile infection
    • Brandt LJ. American Journal of Gastroenterology Lecture: Intestinal microbiota and the role of fecal microbiota transplant (FMT) in treatment of C. difficile infection. Am J Gastroenterol 2013;108:177-185.
    • (2013) Am J Gastroenterol , vol.108 , pp. 177-185
    • Brandt, L.J.1
  • 9
    • 15744374565 scopus 로고    scopus 로고
    • Lactobacillus and bifidobacterium in irritable bowel syndrome: Symptom responses and relationship to cytokine profiles
    • O'Mahony L, McCarthy J, Kelly P, Hurley G, Luo F, Chen K, et al. Lactobacillus and bifidobacterium in irritable bowel syndrome: symptom responses and relationship to cytokine profiles. Gastroenterology 2005;128:541-551.
    • (2005) Gastroenterology , vol.128 , pp. 541-551
    • O'Mahony, L.1    McCarthy, J.2    Kelly, P.3    Hurley, G.4    Luo, F.5    Chen, K.6
  • 10
    • 84856935253 scopus 로고    scopus 로고
    • Infection control in the multidrugresistant era: Tending the human microbiome
    • Tosh PK, McDonald LC. Infection control in the multidrugresistant era: tending the human microbiome. Clin Infect Dis 2012;54:707-713.
    • (2012) Clin Infect Dis , vol.54 , pp. 707-713
    • Tosh, P.K.1    McDonald, L.C.2
  • 11
    • 84872969494 scopus 로고    scopus 로고
    • Gut microbiome composition is linked to whole grain-induced immunological improvements
    • Martínez I, Lattimer JM, Hubach KL, Case JA, Yang J, Weber CG, et al. Gut microbiome composition is linked to whole grain-induced immunological improvements. ISME J 2013;7:269-280.
    • (2013) ISME J , vol.7 , pp. 269-280
    • Martínez, I.1    Lattimer, J.M.2    Hubach, K.L.3    Case, J.A.4    Yang, J.5    Weber, C.G.6
  • 13
    • 84879886792 scopus 로고    scopus 로고
    • The role of microbes and autoimmunity in the pathogenesis of neuropsychiatric illness
    • Hornig M. The role of microbes and autoimmunity in the pathogenesis of neuropsychiatric illness. Curr Opin Rheumatol 2013;25:488-795.
    • (2013) Curr Opin Rheumatol , vol.25 , pp. 488-795
    • Hornig, M.1
  • 14
    • 0024417450 scopus 로고
    • Hay fever, hygiene, and household size
    • Strachan DP. Hay fever, hygiene, and household size. BMJ 1989;299:1259-1260.
    • (1989) BMJ , vol.299 , pp. 1259-1260
    • Strachan, D.P.1
  • 15
    • 0141885424 scopus 로고    scopus 로고
    • Innate immune responses to mycobacteria and the downregulation of atopic responses
    • Rook GA, Martinelli R, Brunet LR. Innate immune responses to mycobacteria and the downregulation of atopic responses. Curr Opin Allergy Clin Immunol 2003;3:337-342.
    • (2003) Curr Opin Allergy Clin Immunol , vol.3 , pp. 337-342
    • Rook, G.A.1    Martinelli, R.2    Brunet, L.R.3
  • 16
    • 77949371211 scopus 로고    scopus 로고
    • 99th Dahlem conference on infection, inflammation and chronic inflammatory disorders: Darwinian medicine and the 'hygiene' or 'old friends' hypothesis
    • Rook GA. 99th Dahlem conference on infection, inflammation and chronic inflammatory disorders: darwinian medicine and the 'hygiene' or 'old friends' hypothesis. Clin Exp Immunol 2010;160:70-79.
    • (2010) Clin Exp Immunol , vol.160 , pp. 70-79
    • Rook, G.A.1
  • 17
    • 84937639025 scopus 로고    scopus 로고
    • Hygiene and other early childhood influences on the subsequent function of the immune system
    • Rook GA, Lowry CA, Raison CL. Hygiene and other early childhood influences on the subsequent function of the immune system. Brain Res 2015;1617:47-62.
    • (2015) Brain Res , vol.1617 , pp. 47-62
    • Rook, G.A.1    Lowry, C.A.2    Raison, C.L.3
  • 19
    • 79960464084 scopus 로고    scopus 로고
    • Probiotics function mechanistically as delivery vehicles for neuroactive compounds: Microbial endocrinology in the design and use of probiotics
    • Lyte M. Probiotics function mechanistically as delivery vehicles for neuroactive compounds: Microbial endocrinology in the design and use of probiotics. Bioessays 2011;33: 574-581.
    • (2011) Bioessays , vol.33 , pp. 574-581
    • Lyte, M.1
  • 20
    • 53049087266 scopus 로고    scopus 로고
    • The probiotic Bifidobacteria infantis: An assessment of potential antidepressant properties in the rat
    • Desbonnet L, Garrett L, Clarke G, Bienenstock J, Dinan TG. The probiotic Bifidobacteria infantis: An assessment of potential antidepressant properties in the rat. J Psychiatr Res 2008;43:164-174.
    • (2008) J Psychiatr Res , vol.43 , pp. 164-174
    • Desbonnet, L.1    Garrett, L.2    Clarke, G.3    Bienenstock, J.4    Dinan, T.G.5
  • 22
    • 65449159712 scopus 로고    scopus 로고
    • The relationship between intestinal microbiota and the central nervous system in normal gastrointestinal function and disease
    • Collins SM, Bercik P. The relationship between intestinal microbiota and the central nervous system in normal gastrointestinal function and disease. Gastroenterology 2009;136:2003-2014.
    • (2009) Gastroenterology , vol.136 , pp. 2003-2014
    • Collins, S.M.1    Bercik, P.2
  • 23
    • 84859648364 scopus 로고    scopus 로고
    • Gender-dependent consequences of chronic olanzapine in the rat: Effects on body weight, inflammatory, metabolic and microbiota parameters
    • Davey KJ, O'Mahony SM, Schellekens H, O'Sullivan O, Bienenstock J, Cotter PD, et al. Gender-dependent consequences of chronic olanzapine in the rat: effects on body weight, inflammatory, metabolic and microbiota parameters. Psychopharmacology (Berl) 2012;221:155-169.
    • (2012) Psychopharmacology (Berl) , vol.221 , pp. 155-169
    • Davey, K.J.1    O'Mahony, S.M.2    Schellekens, H.3    O'Sullivan, O.4    Bienenstock, J.5    Cotter, P.D.6
  • 24
    • 0033191047 scopus 로고    scopus 로고
    • Maternal separation disrupts the integrity of the intestinal microflora in infant rhesus monkeys
    • Bailey MT, Coe CL. Maternal separation disrupts the integrity of the intestinal microflora in infant rhesus monkeys. Dev Psychobiol 1999;35:146-155.
    • (1999) Dev Psychobiol , vol.35 , pp. 146-155
    • Bailey, M.T.1    Coe, C.L.2
  • 25
    • 58149291318 scopus 로고    scopus 로고
    • Early life stress alters behavior, immunity, and microbiota in rats: Implications for irritable bowel syndrome and psychiatric illnesses
    • O'Mahony SM, Marchesi JR, Scully P, Codling C, Ceolho AM, Quigley EM, et al. Early life stress alters behavior, immunity, and microbiota in rats: implications for irritable bowel syndrome and psychiatric illnesses. Biol Psychiatry 2009;65:263-267.
    • (2009) Biol Psychiatry , vol.65 , pp. 263-267
    • O'Mahony, S.M.1    Marchesi, J.R.2    Scully, P.3    Codling, C.4    Ceolho, A.M.5    Quigley, E.M.6
  • 26
    • 77649190768 scopus 로고    scopus 로고
    • Coordination of tolerogenic immune responses by the commensal microbiota
    • Round JL, O'Connell RM, Mazmanian SK. Coordination of tolerogenic immune responses by the commensal microbiota. J Autoimmun 2010;34:J220-J225.
    • (2010) J Autoimmun , vol.34 , pp. J220-J225
    • Round, J.L.1    O'Connell, R.M.2    Mazmanian, S.K.3
  • 27
    • 84860216630 scopus 로고    scopus 로고
    • Microbial exposure during early life has persistent effects on natural killer T cell function
    • Olszak T, An D, Zeissig S, Vera MP, Richter J, Franke A, et al. Microbial exposure during early life has persistent effects on natural killer T cell function. Science 2012; 336:489-493.
    • (2012) Science , vol.336 , pp. 489-493
    • Olszak, T.1    An, D.2    Zeissig, S.3    Vera, M.P.4    Richter, J.5    Franke, A.6
  • 28
    • 59849113547 scopus 로고    scopus 로고
    • Microbes in gastrointestinal health and disease
    • Neish AS. Microbes in gastrointestinal health and disease. Gastroenterology 2009;136:65-80.
    • (2009) Gastroenterology , vol.136 , pp. 65-80
    • Neish, A.S.1
  • 29
    • 82355168363 scopus 로고    scopus 로고
    • Probiotics in the treatment of depression: Science or science fiction
    • Dinan TG, Quigley EM. Probiotics in the treatment of depression: science or science fiction? Aust N Z J Psychiatry 2011;45:1023-1025.
    • (2011) Aust N Z J Psychiatry , vol.45 , pp. 1023-1025
    • Dinan, T.G.1    Quigley, E.M.2
  • 31
    • 84880925130 scopus 로고    scopus 로고
    • Role of the Toll Like receptor (TLR) radical cycle in chronic inflammation: Possible treatments targeting the TLR4 pathway
    • Lucas K, Maes M. Role of the Toll Like receptor (TLR) radical cycle in chronic inflammation: possible treatments targeting the TLR4 pathway. Mol Neurobiol 2013;48:190-204.
    • (2013) Mol Neurobiol , vol.48 , pp. 190-204
    • Lucas, K.1    Maes, M.2
  • 32
    • 77950343791 scopus 로고    scopus 로고
    • Pattern recognition receptors and inflammation
    • Takeuchi O, Akira S. Pattern recognition receptors and inflammation. Cell 2010;140:805-820.
    • (2010) Cell , vol.140 , pp. 805-820
    • Takeuchi, O.1    Akira, S.2
  • 33
    • 80052334860 scopus 로고    scopus 로고
    • Enhanced peripheral toll-like receptor responses in psychosis: Further evidence of a pro-inflammatory phenotype
    • McKernan DP, Dennison U, Gaszner G, Cryan JF, Dinan TG. Enhanced peripheral toll-like receptor responses in psychosis: further evidence of a pro-inflammatory phenotype. Transl Psychiatry 2011;1:e36.
    • (2011) Transl Psychiatry , vol.1 , pp. e36
    • McKernan, D.P.1    Dennison, U.2    Gaszner, G.3    Cryan, J.F.4    Dinan, T.G.5
  • 34
    • 84871241311 scopus 로고    scopus 로고
    • Immune-neural connections: How the immune system's response to infectious agents influences behavior
    • McCusker RH, Kelley KW. Immune-neural connections: how the immune system's response to infectious agents influences behavior. J Exp Biol 2013;216:84-98.
    • (2013) J Exp Biol , vol.216 , pp. 84-98
    • McCusker, R.H.1    Kelley, K.W.2
  • 36
    • 84862779106 scopus 로고    scopus 로고
    • Neurobehavioral effects of interferon-? in patients with hepatitis-C: Symptom dimensions and responsiveness to paroxetine
    • McNutt MD, Liu S, Manatunga A, Royster EB, Raison CL, Woolwine BJ, et al. Neurobehavioral effects of interferon-? in patients with hepatitis-C: symptom dimensions and responsiveness to paroxetine. Neuropsychopharmacology 2012;37:1444-1454.
    • (2012) Neuropsychopharmacology , vol.37 , pp. 1444-1454
    • McNutt, M.D.1    Liu, S.2    Manatunga, A.3    Royster, E.B.4    Raison, C.L.5    Woolwine, B.J.6
  • 37
    • 84899504520 scopus 로고    scopus 로고
    • Effects of Brilliant Blue G on serum tumor necrosis factor-? Levels and depression-like behavior in mice after lipopolysaccharide administration
    • Ma M, Ren Q, Zhang JC, Hashimoto K. Effects of Brilliant Blue G on serum tumor necrosis factor-? levels and depression-like behavior in mice after lipopolysaccharide administration. Clin Psychopharmacol Neurosci 2014;12: 31-36.
    • (2014) Clin Psychopharmacol Neurosci , vol.12 , pp. 31-36
    • Ma, M.1    Ren, Q.2    Zhang, J.C.3    Hashimoto, K.4
  • 38
    • 15944377405 scopus 로고    scopus 로고
    • The negative immunoregulatory effects of fluoxetine in relation to the cAMP-dependent PKA pathway
    • Maes M, Kenis G, Kubera M, De Baets M, Steinbusch H, Bosmans E. The negative immunoregulatory effects of fluoxetine in relation to the cAMP-dependent PKA pathway. Int Immunopharmacol 2005;5:609-618.
    • (2005) Int Immunopharmacol , vol.5 , pp. 609-618
    • Maes, M.1    Kenis, G.2    Kubera, M.3    De Baets, M.4    Steinbusch, H.5    Bosmans, E.6
  • 40
    • 0036964196 scopus 로고    scopus 로고
    • Gut flora-mechanisms of regulation
    • Macpherson AJ, Uhr T. Gut flora-mechanisms of regulation. Eur J Surg Suppl 2002;(587):53-57.
    • (2002) Eur J Surg Suppl , Issue.587 , pp. 53-57
    • Macpherson, A.J.1    Uhr, T.2
  • 41
    • 40949119000 scopus 로고    scopus 로고
    • Lactobacillus GG has in vitro effects on enhanced interleukin-10 and interferon-gamma release of mononuclear cells but no in vivo effects in supplemented mothers and their neonates
    • Kopp MV, Goldstein M, Dietschek A, Sofke J, Heinzmann A, Urbanek R. Lactobacillus GG has in vitro effects on enhanced interleukin-10 and interferon-gamma release of mononuclear cells but no in vivo effects in supplemented mothers and their neonates. Clin Exp Allergy 2008;38: 602-610.
    • (2008) Clin Exp Allergy , vol.38 , pp. 602-610
    • Kopp, M.V.1    Goldstein, M.2    Dietschek, A.3    Sofke, J.4    Heinzmann, A.5    Urbanek, R.6
  • 42
    • 84861992014 scopus 로고    scopus 로고
    • The application of ecological theory toward an understanding of the human microbiome
    • Costello EK, Stagaman K, Dethlefsen L, Bohannan BJ, Relman DA. The application of ecological theory toward an understanding of the human microbiome. Science 2012; 336:1255-1262.
    • (2012) Science , vol.336 , pp. 1255-1262
    • Costello, E.K.1    Stagaman, K.2    Dethlefsen, L.3    Bohannan, B.J.4    Relman, D.A.5
  • 43
    • 80051780284 scopus 로고    scopus 로고
    • The new link between gut-brain axis and neuropsychiatric disorders
    • Fetissov SO, Déchelotte P. The new link between gut-brain axis and neuropsychiatric disorders. Curr Opin Clin Nutr Metab Care 2011;14:477-482.
    • (2011) Curr Opin Clin Nutr Metab Care , vol.14 , pp. 477-482
    • Fetissov, S.O.1    Déchelotte, P.2
  • 44
    • 84866323423 scopus 로고    scopus 로고
    • Prevention of gut leakiness by a probiotic treatment leads to attenuated HPA response to an acute psychological stress in rats
    • Ait-Belgnaoui A, Durand H, Cartier C, Chaumaz G, Eutamene H, Ferrier L, et al. Prevention of gut leakiness by a probiotic treatment leads to attenuated HPA response to an acute psychological stress in rats. Psychoneuroendocrinology 2012;37:1885-1895.
    • (2012) Psychoneuroendocrinology , vol.37 , pp. 1885-1895
    • Ait-Belgnaoui, A.1    Durand, H.2    Cartier, C.3    Chaumaz, G.4    Eutamene, H.5    Ferrier, L.6
  • 45
    • 84933678330 scopus 로고    scopus 로고
    • Microbiota, the immune system, black moods and the brain-melancholia updated
    • Smythies LE, Smythies JR. Microbiota, the immune system, black moods and the brain-melancholia updated. Front Hum Neurosci 2014;8:720.
    • (2014) Front Hum Neurosci , vol.8 , pp. 720
    • Smythies, L.E.1    Smythies, J.R.2
  • 46
    • 84881023923 scopus 로고    scopus 로고
    • Discordant patterns of bacterial translocation markers and implications for innate immune imbalances in schizophrenia
    • Severance EG, Gressitt KL, Stallings CR, Origoni AE, Khushalani S, Leweke FM, et al. Discordant patterns of bacterial translocation markers and implications for innate immune imbalances in schizophrenia. Schizophr Res 2013;148:130-137.
    • (2013) Schizophr Res , vol.148 , pp. 130-137
    • Severance, E.G.1    Gressitt, K.L.2    Stallings, C.R.3    Origoni, A.E.4    Khushalani, S.5    Leweke, F.M.6
  • 48
    • 34247899152 scopus 로고    scopus 로고
    • Gut hormones and appetite control
    • Wren AM, Bloom SR. Gut hormones and appetite control. Gastroenterology 2007;132:2116-2130.
    • (2007) Gastroenterology , vol.132 , pp. 2116-2130
    • Wren, A.M.1    Bloom, S.R.2
  • 49
    • 0037509909 scopus 로고    scopus 로고
    • Regulation of short-chain fatty acid production
    • Macfarlane S, Macfarlane GT. Regulation of short-chain fatty acid production. Proc Nutr Soc 2003;62:67-72.
    • (2003) Proc Nutr Soc , vol.62 , pp. 67-72
    • Macfarlane, S.1    Macfarlane, G.T.2
  • 50
    • 84878917603 scopus 로고    scopus 로고
    • Short-chain fatty acid fermentation products of the gut microbiome: Implications in autism spectrum disorders
    • Macfabe DF. Short-chain fatty acid fermentation products of the gut microbiome: implications in autism spectrum disorders. Microb Ecol Health Dis 2012;23. doi: 10. 3402/ mehd. v23i0. 19260.
    • (2012) Microb Ecol Health Dis , vol.23
    • Macfabe, D.F.1
  • 51
    • 84878579044 scopus 로고    scopus 로고
    • The gut microbiota suppresses insulin-mediated fat accumulation via the short-chain fatty acid receptor GPR43
    • Kimura I, Ozawa K, Inoue D, Imamura T, Kimura K, Maeda T, et al. The gut microbiota suppresses insulin-mediated fat accumulation via the short-chain fatty acid receptor GPR43. Nat Commun 2013;4:1829.
    • (2013) Nat Commun , vol.4 , pp. 1829
    • Kimura, I.1    Ozawa, K.2    Inoue, D.3    Imamura, T.4    Kimura, K.5    Maeda, T.6
  • 52
    • 0036283970 scopus 로고    scopus 로고
    • Evidences for vagus nerve in maintenance of immune balance and transmission of immune information from gut to brain in STM-infected rats
    • Wang X, Wang BR, Zhang XJ, Xu Z, Ding YQ, Ju G. Evidences for vagus nerve in maintenance of immune balance and transmission of immune information from gut to brain in STM-infected rats. World J Gastroenterol 2002;8:540-545.
    • (2002) World J Gastroenterol , vol.8 , pp. 540-545
    • Wang, X.1    Wang, B.R.2    Zhang, X.J.3    Xu, Z.4    Ding, Y.Q.5    Ju, G.6
  • 53
    • 0034713266 scopus 로고    scopus 로고
    • Vagus nerve stimulation attenuates the systemic inflammatory response to endotoxin
    • Borovikova LV, Ivanova S, Zhang M, Yang H, Botchkina GI, Watkins LR, et al. Vagus nerve stimulation attenuates the systemic inflammatory response to endotoxin. Nature 2000;405:458-462.
    • (2000) Nature , vol.405 , pp. 458-462
    • Borovikova, L.V.1    Ivanova, S.2    Zhang, M.3    Yang, H.4    Botchkina, G.I.5    Watkins, L.R.6
  • 56
    • 84875821334 scopus 로고    scopus 로고
    • Effect of intestinal microbial ecology on the developing brain
    • Douglas-Escobar M, Elliott E, Neu J. Effect of intestinal microbial ecology on the developing brain. JAMA Pediatr 2013;167:374-379.
    • (2013) JAMA Pediatr , vol.167 , pp. 374-379
    • Douglas-Escobar, M.1    Elliott, E.2    Neu, J.3
  • 57
    • 0032144624 scopus 로고    scopus 로고
    • Anxiogenic effect of subclinical bacterial infection in mice in the absence of overt immune activation
    • Lyte M, Varcoe JJ, Bailey MT. Anxiogenic effect of subclinical bacterial infection in mice in the absence of overt immune activation. Physiol Behav 1998;65:63-68.
    • (1998) Physiol Behav , vol.65 , pp. 63-68
    • Lyte, M.1    Varcoe, J.J.2    Bailey, M.T.3
  • 58
    • 77957142793 scopus 로고    scopus 로고
    • Effects of the probiotic Bifidobacterium infantis in the maternal separation model of depression
    • Desbonnet L, Garrett L, Clarke G, Kiely B, Cryan JF, Dinan TG. Effects of the probiotic Bifidobacterium infantis in the maternal separation model of depression. Neuroscience 2010;170:1179-1188.
    • (2010) Neuroscience , vol.170 , pp. 1179-1188
    • Desbonnet, L.1    Garrett, L.2    Clarke, G.3    Kiely, B.4    Cryan, J.F.5    Dinan, T.G.6
  • 59
    • 84886724158 scopus 로고    scopus 로고
    • Psychobiotics: A novel class of psychotropic
    • Dinan TG, Stanton C, Cryan JF. Psychobiotics: a novel class of psychotropic. Biol Psychiatry 2013;74:720-726.
    • (2013) Biol Psychiatry , vol.74 , pp. 720-726
    • Dinan, T.G.1    Stanton, C.2    Cryan, J.F.3
  • 61
    • 84878241830 scopus 로고    scopus 로고
    • The microbiome-gut-brain axis during early life regulates the hippocampal serotonergic system in a sex-dependent manner
    • Clarke G, Grenham S, Scully P, Fitzgerald P, Moloney RD, Shanahan F, et al. The microbiome-gut-brain axis during early life regulates the hippocampal serotonergic system in a sex-dependent manner. Mol Psychiatry 2013;18:666-673.
    • (2013) Mol Psychiatry , vol.18 , pp. 666-673
    • Clarke, G.1    Grenham, S.2    Scully, P.3    Fitzgerald, P.4    Moloney, R.D.5    Shanahan, F.6
  • 62
    • 79953160733 scopus 로고    scopus 로고
    • Assessment of psychotropic-like properties of a probiotic formulation (Lactobacillus helveticus R0052 and Bifidobacterium longum R0175) in rats and human subjects
    • Messaoudi M, Lalonde R, Violle N, Javelot H, Desor D, Nejdi A, et al. Assessment of psychotropic-like properties of a probiotic formulation (Lactobacillus helveticus R0052 and Bifidobacterium longum R0175) in rats and human subjects. Br J Nutr 2011;105:755-764.
    • (2011) Br J Nutr , vol.105 , pp. 755-764
    • Messaoudi, M.1    Lalonde, R.2    Violle, N.3    Javelot, H.4    Desor, D.5    Nejdi, A.6
  • 63
    • 85046980563 scopus 로고    scopus 로고
    • Beneficial psychological effects of a probiotic formulation (Lactobacillus helveticus R0052 and Bifidobacterium longum R0175) in healthy human volunteers
    • Messaoudi M, Violle N, Bisson JF, Desor D, Javelot H, Rougeot C. Beneficial psychological effects of a probiotic formulation (Lactobacillus helveticus R0052 and Bifidobacterium longum R0175) in healthy human volunteers. Gut Microbes 2011;2:256-261.
    • (2011) Gut Microbes , vol.2 , pp. 256-261
    • Messaoudi, M.1    Violle, N.2    Bisson, J.F.3    Desor, D.4    Javelot, H.5    Rougeot, C.6
  • 64
    • 80052965474 scopus 로고    scopus 로고
    • Ingestion of Lactobacillus strain regulates emotional behavior and central GABA receptor expression in a mouse via the vagus nerve
    • Bravo JA, Forsythe P, Chew MV, Escaravage E, Savignac HM, Dinan TG, et al. Ingestion of Lactobacillus strain regulates emotional behavior and central GABA receptor expression in a mouse via the vagus nerve. Proc Natl Acad Sci U S A 2011;108:16050-16055.
    • (2011) Proc Natl Acad Sci U S A , vol.108 , pp. 16050-16055
    • Bravo, J.A.1    Forsythe, P.2    Chew, M.V.3    Escaravage, E.4    Savignac, H.M.5    Dinan, T.G.6
  • 65
    • 84883655231 scopus 로고    scopus 로고
    • Effects of Lactobacillus helveticus on murine behavior are dependent on diet and genotype and correlate with alterations in the gut microbiome
    • Ohland CL, Kish L, Bell H, Thiesen A, Hotte N, Pankiv E, et al. Effects of Lactobacillus helveticus on murine behavior are dependent on diet and genotype and correlate with alterations in the gut microbiome. Psychoneuroendocrinology 2013;38:1738-1747.
    • (2013) Psychoneuroendocrinology , vol.38 , pp. 1738-1747
    • Ohland, C.L.1    Kish, L.2    Bell, H.3    Thiesen, A.4    Hotte, N.5    Pankiv, E.6
  • 67
  • 68
    • 84884354746 scopus 로고    scopus 로고
    • So depression is an inflammatory disease, but where does the inflammation come from
    • Berk M, Williams LJ, Jacka FN, O'Neil A, Pasco JA, Moylan S, et al. So depression is an inflammatory disease, but where does the inflammation come from? BMC Med 2013;11:200.
    • (2013) BMC Med , vol.11 , pp. 200
    • Berk, M.1    Williams, L.J.2    Jacka, F.N.3    O'Neil, A.4    Pasco, J.A.5    Moylan, S.6
  • 69
    • 84916594191 scopus 로고    scopus 로고
    • The gut microbiome and diet in psychiatry: Focus on depression
    • Dash S, Clarke G, Berk M, Jacka FN. The gut microbiome and diet in psychiatry: focus on depression. Curr Opin Psychiatry 2015;28:1-6.
    • (2015) Curr Opin Psychiatry , vol.28 , pp. 1-6
    • Dash, S.1    Clarke, G.2    Berk, M.3    Jacka, F.N.4
  • 70
    • 78049396557 scopus 로고
    • The treatment of melancholia by the lactic acid bacillus
    • Phillips JGP. The treatment of melancholia by the lactic acid bacillus. Br J Psychiatry 1910;56:422-431.
    • (1910) Br J Psychiatry , vol.56 , pp. 422-431
    • Phillips, J.G.P.1
  • 71
    • 40049089730 scopus 로고    scopus 로고
    • Probiotics in the United States
    • Vanderhoof JA, Young R. Probiotics in the United States. Clin Infect Dis 2008;46 Suppl 2:S67-S72.
    • (2008) Clin Infect Dis , vol.46 , pp. S67-S72
    • Vanderhoof, J.A.1    Young, R.2
  • 72
    • 84922800681 scopus 로고    scopus 로고
    • The "psychomicrobiotic": Targeting microbiota in major psychiatric disorders: A systematic review
    • Fond G, Boukouaci W, Chevalier G, Regnault A, Eberl G, Hamdani N, et al. The "psychomicrobiotic": Targeting microbiota in major psychiatric disorders: a systematic review. Pathol Biol (Paris) 2015;63:35-42.
    • (2015) Pathol Biol (Paris) , vol.63 , pp. 35-42
    • Fond, G.1    Boukouaci, W.2    Chevalier, G.3    Regnault, A.4    Eberl, G.5    Hamdani, N.6
  • 74
    • 84949468591 scopus 로고    scopus 로고
    • Gut-brain axis: The role of gut microbiota in the psychiatric disorders
    • Evrensel A, Ceylan ME. Gut-brain axis: the role of gut microbiota in the psychiatric disorders. Curr Approach Psychiatry 2015;7:461-472.
    • (2015) Curr Approach Psychiatry , vol.7 , pp. 461-472
    • Evrensel, A.1    Ceylan, M.E.2


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