HDAC Inhibitor Sodium Butyrate-Mediated Epigenetic Regulation Enhances Neuroprotective Function of Microglia During Ischemic Stroke

Molecular Neurobiology

Volumn 54, Issue 8, 2017, Pages 6391-6411

  Patnala, Radhika ^a   Arumugam, Thiruma V ^a   Gupta, Neelima ^a   Dheen, S Thameem ^a  

^a NATIONAL UNIVERSITY OF SINGAPORE   (Singapore)

Author keywords

Epigenetics; H3K9ac; HDAC inhibitors; Ischemia; Microglia; Neuroinflammation

Indexed keywords

BUTYRIC ACID; HISTONE DEACETYLASE INHIBITOR; INDUCIBLE NITRIC OXIDE SYNTHASE; INTERLEUKIN 10; INTERLEUKIN 6; LIPOPOLYSACCHARIDE; STAT1 PROTEIN; TUMOR NECROSIS FACTOR; NEUROPROTECTIVE AGENT;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BRAIN CORTEX; BRAIN ISCHEMIA; C57BL/6N MOUSE; CONTROLLED STUDY; CORPUS STRIATUM; DOWN REGULATION; ENZYME ACTIVATION; EPIGENETICS; EXPERIMENTAL MOUSE; GENE EXPRESSION; GENETIC TRANSCRIPTION; HIPPOCAMPUS; HISTONE MODIFICATION; MALE; MICROGLIA; MIDDLE CEREBRAL ARTERY OCCLUSION; MOUSE; NERVOUS SYSTEM INFLAMMATION; NEUROPROTECTION; NONHUMAN; PROMOTER REGION; PROTEIN EXPRESSION; WISTAR RAT; ANIMAL; BRAIN; CELL CULTURE; CEREBROVASCULAR ACCIDENT; DRUG EFFECT; GENE EXPRESSION REGULATION; GENETIC EPIGENESIS; METABOLISM; PATHOLOGY; RAT;

ANIMALS; BRAIN; BRAIN ISCHEMIA; BUTYRIC ACID; CELLS, CULTURED; EPIGENESIS, GENETIC; GENE EXPRESSION REGULATION; HISTONE DEACETYLASE INHIBITORS; MALE; MICE; MICROGLIA; NEUROPROTECTIVE AGENTS; RATS; RATS, WISTAR; STROKE;

EID: 84990902419     PISSN: 08937648     EISSN: 15591182     Source Type: Journal    
DOI: 10.1007/s12035-016-0149-z     Document Type: Article

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