Cardiopatch platform enables maturation and scale-up of human pluripotent stem cell-derived engineered heart tissues

Nature Communications

Volumn 8, Issue 1, 2017, Pages

  Shadrin, Ilya Y ^a   Allen, Brian W ^a   Qian, Ying ^a   Jackman, Christopher P ^a   Carlson, Aaron L ^a   Juhas, Mark E ^a   Bursac, Nenad ^a  

^a Duke University   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BIOLOGICAL MARKER; CALCIUM;

BIOENGINEERING; BIOMARKER; CARDIOVASCULAR SYSTEM; CELLS AND CELL COMPONENTS; DISEASE TREATMENT; DRUG DEVELOPMENT; MATURATION;

ACTION POTENTIAL DURATION; ADULT; ANIMAL CELL; ANIMAL TISSUE; ARRHYTHMOGENESIS; ARTICLE; CARDIAC MUSCLE; CARDIAC MUSCLE CELL; CARDIOPATCH; CELL DIFFERENTIATION; CELL ENGINEERING; CELL MATURATION; CELL PROLIFERATION; ENGINEERED HEART TISSUE; EXCITATION CONTRACTION COUPLING; GENE EXPRESSION; HEART TISSUE; HUMAN; INDUCED PLURIPOTENT STEM CELL; MOUSE; NONHUMAN; PLURIPOTENT STEM CELL; RAT; REPOLARIZATION; SCALE UP; SCANNING ELECTRON MICROSCOPY; SMOOTH MUSCLE CELL; TRANSMISSION ELECTRON MICROSCOPY; WESTERN BLOTTING; ANIMAL; CELL CULTURE; CELL LINE; CYTOLOGY; DISEASE MODEL; HEART ARRHYTHMIA; HEART CONTRACTION; HEART INFARCTION; MALE; METABOLISM; NUDE MOUSE; PATHOLOGY; PHYSIOLOGY; PROCEDURES; SARCOMERE; TISSUE ENGINEERING; TRANSPLANTATION; XENOGRAFT;

MUS MUSCULUS; RATTUS;

ANIMALS; ARRHYTHMIAS, CARDIAC; CALCIUM; CELL DIFFERENTIATION; CELL LINE; CELLS, CULTURED; DISEASE MODELS, ANIMAL; HETEROGRAFTS; HUMANS; INDUCED PLURIPOTENT STEM CELLS; MALE; MICE; MICE, NUDE; MYOCARDIAL CONTRACTION; MYOCARDIAL INFARCTION; MYOCARDIUM; MYOCYTES, CARDIAC; PLURIPOTENT STEM CELLS; RATS; SARCOMERES; TISSUE ENGINEERING;

EID: 85036528377     PISSN: None     EISSN: 20411723     Source Type: Journal    
DOI: 10.1038/s41467-017-01946-x     Document Type: Article

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