Human engineered heart muscles engraft and survive long term in a rodent myocardial infarction model

Circulation Research

Volumn 117, Issue 8, 2015, Pages 720-730

  Riegler, Johannes ^a   Tiburcy, Malte ^c   Ebert, Antje ^a   Tzatzalos, Evangeline ^a   Raaz, Uwe ^a   Abilez, Oscar J ^a   Shen, Qi ^a   Kooreman, Nigel G ^a   Neofytou, Evgenios ^a   Chen, Vincent C ^d   Wang, Mouer ^a   Meyer, Tim ^c   Tsao, Philip S ^a,b   Connolly, Andrew J ^a,d   Couture, Larry A ^d   Gold, Joseph D ^a   Zimmermann, Wolfram H ^c   Wu, Joseph C ^a  

^a STANFORD UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b VA PALO ALTO HEALTH CARE SYSTEM   (United States)

^c UNIVERSITY OF GÖTTINGEN   (Germany)

^d CITY OF HOPE NATIONAL MEDICAL CENTER   (United States)

Author keywords

Cardiac function tests; Cardiac MRI; Cell survival; Myocardial infarction; Myocardial ischemia; Tissue engineering; Transplantation

Indexed keywords

BETA1 INTEGRIN; CONNEXIN 43; MYOSIN HEAVY CHAIN BETA; SMOOTH MUSCLE ACTIN; TACROLIMUS; TROPONIN T; BIOLOGICAL MARKER; GJA1 PROTEIN, HUMAN; IMMUNOSUPPRESSIVE AGENT;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CARDIAC GRAFT REJECTION; CARDIOVASCULAR MAGNETIC RESONANCE; CELL SURVIVAL; CELL VIABILITY; CONTROLLED STUDY; DISEASE COURSE; EMBRYONIC STEM CELL; ENGRAFTMENT; GRAFT SURVIVAL; HAMARTOMA; HEART EJECTION FRACTION; HEART FIBROBLAST; HEART FUNCTION; HEART FUNCTION TEST; HEART GRAFT; HEART INFARCTION; HEART INFARCTION SIZE; HEART MUSCLE; HEART MUSCLE CELL; HEART MUSCLE CONTRACTILITY; HISTOLOGY; HUMAN; HUMAN CELL; IMMUNOCOMPETENCE; IMMUNOSUPPRESSIVE TREATMENT; LONG TERM SURVIVAL; MACROPHAGE; MALE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; REPERFUSION INJURY; SARCOMERE; TERATOMA; TISSUE ENGINEERING; XENOGRAFT; ADVERSE EFFECTS; ANIMAL; CARDIAC MUSCLE CELL; CELL DIFFERENTIATION; CELL LINE; DISEASE MODEL; GENETIC TRANSFECTION; HEART CONTRACTION; HEART PAPILLARY MUSCLE; HEART STROKE VOLUME; HEART TRANSPLANTATION; IMMUNOLOGY; METABOLISM; MYOCARDIAL INFARCTION; NUDE RAT; PATHOLOGY; PATHOPHYSIOLOGY; PROCEDURES; SPRAGUE DAWLEY RAT; TIME FACTOR; TRANSPLANTATION;

ANIMALS; BIOMARKERS; CELL DIFFERENTIATION; CELL LINE; CELL SURVIVAL; CONNEXIN 43; DISEASE MODELS, ANIMAL; EMBRYONIC STEM CELLS; GRAFT SURVIVAL; HEART TRANSPLANTATION; HETEROGRAFTS; HUMANS; IMMUNOSUPPRESSIVE AGENTS; MALE; MYOCARDIAL CONTRACTION; MYOCARDIAL INFARCTION; MYOCYTES, CARDIAC; PAPILLARY MUSCLES; RATS, NUDE; RATS, SPRAGUE-DAWLEY; STROKE VOLUME; TIME FACTORS; TISSUE ENGINEERING; TRANSFECTION;

EID: 85047288953     PISSN: 00097330     EISSN: 15244571     Source Type: Journal    
DOI: 10.1161/CIRCRESAHA.115.306985     Document Type: Article

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