Immunogenicity and loss of response to TNF inhibitors: Implications for rheumatoid arthritis treatment

Nature Reviews Rheumatology

Volumn 13, Issue 12, 2017, Pages 707-718

  Kalden, Joachim R ^a   Schulze Koops, Hendrik ^b  

^a UNIVERSITY OF ERLANGEN NUREMBERG   (Germany)

^b UNIVERSITY OF MUNICH   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

ADALIMUMAB; BIOLOGICAL PRODUCT; BIOSIMILAR AGENT; DRUG ANTIBODY; ETANERCEPT; HLA DRB1 ANTIGEN; HYBRID PROTEIN; INFLIXIMAB; METHOTREXATE; MONOCLONAL ANTIBODY; TUMOR NECROSIS FACTOR; TUMOR NECROSIS FACTOR INHIBITOR; ANTIRHEUMATIC AGENT;

ANTIBODY DETECTION; ANTIBODY PRODUCTION; BIOLOGICAL THERAPY; CLINICAL DECISION MAKING; COMBINATION DRUG THERAPY; CROSS REACTION; DRUG EFFICACY; DRUG SUBSTITUTION; DRUG TREATMENT FAILURE; ENZYME LINKED IMMUNOSORBENT ASSAY; GEL MOBILITY SHIFT ASSAY; HUMAN; IMMUNOGENICITY; IMMUNOSUPPRESSIVE TREATMENT; MINIMUM PLASMA CONCENTRATION; NONHUMAN; PRIORITY JOURNAL; RADIOIMMUNOASSAY; REVIEW; RHEUMATOID ARTHRITIS; ANTAGONISTS AND INHIBITORS; DRUG RESISTANCE; IMMUNOLOGY; TREATMENT FAILURE;

ANTIBODIES, MONOCLONAL; ANTIRHEUMATIC AGENTS; ARTHRITIS, RHEUMATOID; DRUG RESISTANCE; HUMANS; TREATMENT FAILURE; TUMOR NECROSIS FACTOR-ALPHA;

EID: 85034760402     PISSN: 17594790     EISSN: 17594804     Source Type: Journal    
DOI: 10.1038/nrrheum.2017.187     Document Type: Review

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