Adalimumab trough concentrations in patients with rheumatoid arthritis and psoriatic arthritis treated with concomitant disease-modifying antirheumatic drugs

Annals of the Rheumatic Diseases

Volumn 74, Issue 2, 2014, Pages 474-475

  Vogelzang, Erik Hans ^a   Pouw, M F ^a,b   Nurmohamed, M ^a   Kneepkens, E L ^a   Rispens, T ^b   Wolbink, G J ^a,b   Krieckaert, C L M ^a  

^a Jan Van Breemen Research Institute/Reade   (Netherlands)

^b SANQUIN RESEARCH   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

ADALIMUMAB; DISEASE MODIFYING ANTIRHEUMATIC DRUG; HYDROXYCHLOROQUINE; LEFLUNOMIDE; METHOTREXATE; SALAZOSULFAPYRIDINE;

ARTICLE; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG DOSE INCREASE; ENZYME LINKED IMMUNOSORBENT ASSAY; FOLLOW UP; HUMAN; MAJOR CLINICAL STUDY; MINIMUM PLASMA CONCENTRATION; MONOTHERAPY; PSORIATIC ARTHRITIS; RHEUMATOID ARTHRITIS;

EID: 84925023855     PISSN: 00034967     EISSN: 14682060     Source Type: Journal    
DOI: None     Document Type: Article

References (7)

1. Bartelds GM, Wijbrandts CA, Nurmohamed MT, et al. Clinical response to adalimumab: relationship to anti-adalimumab antibodies and serum adalimumab concentrations in rheumatoid arthritis. Ann Rheum Dis 2007;66:921-6.
2. Vogelzang EH, Kneepkens EL, Nurmohamed MT, et al. Anti-adalimumab antibodies and adalimumab concentrations in psoriatic arthritis; an association with disease activity at 28 and 52 weeks of follow-up. Ann Rheum Dis 2014;73:2178-82.
3. Bartelds GM, Krieckaert CL, Nurmohamed MT, et al. Development of antidrug antibodies against adalimumab and association with disease activity and treatment failure during long-term follow-up. JAMA 2011;305:1460-8.
4. Krieckaert CL, Nurmohamed MT, Wolbink GJ. Methotrexate reduces immunogenicity in adalimumab treated rheumatoid arthritis patients in a dose dependent manner. Ann Rheum Dis 2012;71:1914-15.
5. Pouw MF, Krieckaert CL, Nurmohamed MT, et al. Key findings towards optimising adalimumab treatment: the concetration-effect curve. Ann Rheum Dis Published Online First: 10 Dec 2013. doi:10.1136/annrheumdis-2013-204172
6. Burmester GR, Kivitz AJ, Kupper H, et al. Efficacy and safety of ascending methotrexate dose in combination with adalimumab: the randomised CONCERTO trial. Ann Rheum Dis Published Online First: 18 Feb 2014. doi:10.1136/annrheumdis-2013-204769
7. Mease PJ. Spondyloarthritis: Is methotrexate effective in psoriatic arthritis? Nat Rev Rheumatol 2012;8:251-2.