ANTIBODY BLOOD LEVEL;
ANTIBODY RESPONSE;
ARTICLE;
CHIMERA;
CONCENTRATION RESPONSE;
DRUG PROTEIN BINDING;
HUMAN;
IMMUNOASSAY;
PROTEIN DOMAIN;
PROTEIN FUNCTION;
ANTAGONISTS AND INHIBITORS;
ANTIBODY COMBINING SITE;
IMMUNOLOGY;
Long-term measurement of anti-adalimumab using pH-shift-anti-idiotype antigen binding test shows predictive value and transient antibody formation
Van Schouwenburg PA, Krieckaert CL, Rispens T, et al. Long-term measurement of anti-adalimumab using pH-shift-anti-idiotype antigen binding test shows predictive value and transient antibody formation. Ann Rheum Dis 2013;72:1680-6.
Development of antidrug antibodies against adalimumab and association with disease activity and treatment failure during long-term follow-up
Bartelds GM, Krieckaert CLM, Nurmohamed MT, et al. Development of antidrug antibodies against adalimumab and association with disease activity and treatment failure during long-term follow-up. J Am Med Assoc 2011;305:1460-8.
Individualized monitoring of drug bioavailability and immunogenicity in rheumatoid arthritis patients treated with the tumor necrosis factor alpha inhibitor infliximab
Bendtzen K, Geborek P, Svenson M, et al. Individualized monitoring of drug bioavailability and immunogenicity in rheumatoid arthritis patients treated with the tumor necrosis factor alpha inhibitor infliximab. Arthritis Rheum 2006;54:3782-9.
The impact of neutralizing antibodies on the risk of disease worsening in interferon â-treated relapsing multiple sclerosis: A 5 year post-marketing study
Paolicelli D, D'Onghia M, Pellegrini F, et al. The impact of neutralizing antibodies on the risk of disease worsening in interferon â-treated relapsing multiple sclerosis: a 5 year post-marketing study. J Neurol 2013;260:1562-8.
Adalimumab elicits a restricted anti-idiotypic antibody response in autoimmune patients resulting in functional neutralisation
Van Schouwenburg PA, Van De Stadt LA, De Jong RN, et al. Adalimumab elicits a restricted anti-idiotypic antibody response in autoimmune patients resulting in functional neutralisation. Ann Rheum Dis 2013;72:104-9.
Exploring the binding sites of anti-infliximab antibodies in pediatric patients with rheumatic diseases treated with infliximab
Kosmac M, Avcin T, Toplak N, et al. Exploring the binding sites of anti-infliximab antibodies in pediatric patients with rheumatic diseases treated with infliximab. Pediatr Res 2011;69:243-8.
Restriction of the human in vivo immune response against the mouse monoclonal antibody OKT3
Chatenoud L, Baudrihaye MF, Chkoff N, et al. Restriction of the human in vivo immune response against the mouse monoclonal antibody OKT3. J Immunol 1986;137:830-8. http://www.ncbi.nlm.nih.gov/pubmed/3487589
The minipig as an alternative non-rodent model for immunogenicity testing using the TNFá blockers adalimumab and infliximab
Van Mierlo GJD, Cnubben NHP, Wouters D, et al. The minipig as an alternative non-rodent model for immunogenicity testing using the TNFá blockers adalimumab and infliximab. J Immunotoxicol 2014;11:62-71.
Structural basis for treating tumor necrosis factor á (TNFá)-associated diseases with the therapeutic antibody infliximab
Liang S, Dai J, Hou S, et al. Structural basis for treating tumor necrosis factor á (TNFá)-associated diseases with the therapeutic antibody infliximab. J Biol Chem 2013;288:13799-807.
Comparison of the inhibition mechanisms of adalimumab and infliximab in treating tumor necrosis factor á-associated diseases from a molecular view
Hu S, Liang S, Guo H, et al. Comparison of the inhibition mechanisms of adalimumab and infliximab in treating tumor necrosis factor á-associated diseases from a molecular view. J Biol Chem 2013;288:27059-67.