메뉴 건너뛰기




Volumn 44, Issue 4, 2018, Pages 854-864

Genetic Overlap between Schizophrenia and Volumes of Hippocampus, Putamen, and Intracranial Volume Indicates Shared Molecular Genetic Mechanisms

Author keywords

common genetic variants; conditional false discovery rate; genome wide association study; pleiotropy; subcortical brain structures

Indexed keywords

DCC PROTEIN; DLG2 PROTEIN; FTCDNL1 PROTEIN; ITIH4 PROTEIN; MESSENGER RNA; PROTEIN; SLC4A10 PROTEIN; SPATS2L PROTEIN; TRANSCRIPTION FACTOR FKHRL1; UNCLASSIFIED DRUG;

EID: 85034565370     PISSN: 05867614     EISSN: 17451701     Source Type: Journal    
DOI: 10.1093/schbul/sbx148     Document Type: Article
Times cited : (76)

References (61)
  • 1
    • 84930324327 scopus 로고    scopus 로고
    • Subcortical brain volume abnormalities in 2028 individuals with schizophrenia and 2540 healthy controls via the ENIGMA consortium
    • Apr
    • Van Erp TG, Hibar DP, Rasmussen JM, et al. Subcortical brain volume abnormalities in 2028 individuals with schizophrenia and 2540 healthy controls via the ENIGMA consortium. Mol Psychiatry. Apr 2016;21(4):547-553.
    • (2016) Mol Psychiatry , vol.21 , Issue.4 , pp. 547-553
    • Van Erp, T.G.1    Hibar, D.P.2    Rasmussen, J.M.3
  • 2
    • 84954564378 scopus 로고    scopus 로고
    • Abnormal asymmetries in subcortical brain volume in schizophrenia
    • Oct
    • Okada N, Fukunaga M, Yamashita F, et al. Abnormal asymmetries in subcortical brain volume in schizophrenia. Mol Psychiatry. Oct 2016;21(10):1460-1466.
    • (2016) Mol Psychiatry , vol.21 , Issue.10 , pp. 1460-1466
    • Okada, N.1    Fukunaga, M.2    Yamashita, F.3
  • 4
    • 58149464318 scopus 로고    scopus 로고
    • Common genetic determinants of schizophrenia and bipolar disorder in Swedish families: A population-based study
    • Lichtenstein P, Yip BH, Bjork C, et al. Common genetic determinants of schizophrenia and bipolar disorder in Swedish families: a population-based study. Lancet. 2009;373:234-239.
    • (2009) Lancet , vol.373 , pp. 234-239
    • Lichtenstein, P.1    Yip, B.H.2    Bjork, C.3
  • 5
    • 84926395609 scopus 로고    scopus 로고
    • Common genetic variants influence human subcortical brain structures
    • Hibar DP, Stein JL, Renteria ME, et al. Common genetic variants influence human subcortical brain structures. Nature. Apr 09 2015;520(7546):224-229.
    • Nature. Apr 09 2015 , vol.520 , Issue.7546 , pp. 224-229
    • Hibar, D.P.1    Stein, J.L.2    Renteria, M.E.3
  • 6
    • 84889791496 scopus 로고    scopus 로고
    • A family affair: Brain abnormalities in siblings of patients with schizophrenia
    • Moran ME, Hulshoff Pol H, Gogtay N. A family affair: brain abnormalities in siblings of patients with schizophrenia. Brain. 2013;136:3215-3226.
    • (2013) Brain , vol.136 , pp. 3215-3226
    • Moran, M.E.1    Hulshoff Pol, H.2    Gogtay, N.3
  • 8
    • 0036530059 scopus 로고    scopus 로고
    • Neural systems for recognizing emotion
    • Adolphs R. Neural systems for recognizing emotion. Curr Opin Neurobiol. 2002;12:169-177.
    • (2002) Curr Opin Neurobiol , vol.12 , pp. 169-177
    • Adolphs, R.1
  • 9
    • 84894063548 scopus 로고    scopus 로고
    • Cognitive-motor interactions of the basal ganglia in development
    • Leisman G, Braun-Benjamin O, Melillo R. Cognitive-motor interactions of the basal ganglia in development. Front Syst Neurosci. 2014;8:16.
    • (2014) Front Syst Neurosci , vol.8 , pp. 16
    • Leisman, G.1    Braun-Benjamin, O.2    Melillo, R.3
  • 10
    • 0035969560 scopus 로고    scopus 로고
    • Interactive memory systems in the human brain
    • Poldrack RA, Clark J, Pare-Blagoev EJ, et al. Interactive memory systems in the human brain. Nature. 2001;414:546-550.
    • (2001) Nature , vol.414 , pp. 546-550
    • Poldrack, R.A.1    Clark, J.2    Pare-Blagoev, E.J.3
  • 11
    • 33748302924 scopus 로고    scopus 로고
    • Dopamine-dependent prediction errors underpin rewardseeking behaviour in humans
    • Pessiglione M, Seymour B, Flandin G, Dolan RJ, Frith CD. Dopamine-dependent prediction errors underpin rewardseeking behaviour in humans. Nature. 2006;442:1042-1045.
    • (2006) Nature , vol.442 , pp. 1042-1045
    • Pessiglione, M.1    Seymour, B.2    Flandin, G.3    Dolan, R.J.4    Frith, C.D.5
  • 12
    • 79956002777 scopus 로고    scopus 로고
    • Subcortical brain volumes relate to neurocognition in schizophrenia and bipolar disorder and healthy controls
    • Hartberg CB, Sundet K, Rimol LM, et al. Subcortical brain volumes relate to neurocognition in schizophrenia and bipolar disorder and healthy controls. Prog Neuropsychopharmacol Biol Psychiatry. 2011;35:1122-1130.
    • (2011) Prog Neuropsychopharmacol Biol Psychiatry , vol.35 , pp. 1122-1130
    • Hartberg, C.B.1    Sundet, K.2    Rimol, L.M.3
  • 13
    • 84939784909 scopus 로고    scopus 로고
    • Association of IQ changes and progressive brain changes in patients with schizophrenia
    • Kubota M, Van Haren NE, Haijma SV, et al. Association of IQ changes and progressive brain changes in patients with schizophrenia. JAMA Psychiatry. 2015;72:803-812.
    • (2015) JAMA Psychiatry , vol.72 , pp. 803-812
    • Kubota, M.1    Van Haren, N.E.2    Haijma, S.V.3
  • 14
    • 79952032110 scopus 로고    scopus 로고
    • The physiology, signaling, and pharmacology of dopamine receptors
    • Beaulieu JM, Gainetdinov RR. The physiology, signaling, and pharmacology of dopamine receptors. Pharmacol Rev. 2011;63:182-217.
    • (2011) Pharmacol Rev , vol.63 , pp. 182-217
    • Beaulieu, J.M.1    Gainetdinov, R.R.2
  • 15
    • 79951503453 scopus 로고    scopus 로고
    • Long-term antipsychotic treatment and brain volumes: A longitudinal study of first-episode schizophrenia
    • Ho BC, Andreasen NC, Ziebell S, Pierson R, Magnotta V. Long-term antipsychotic treatment and brain volumes: a longitudinal study of first-episode schizophrenia. Arch Gen Psychiatry. 2011;68:128-137.
    • (2011) Arch Gen Psychiatry , vol.68 , pp. 128-137
    • Ho, B.C.1    Andreasen, N.C.2    Ziebell, S.3    Pierson, R.4    Magnotta, V.5
  • 16
    • 84904804929 scopus 로고    scopus 로고
    • Biological insights from 108 schizophreniaassociated genetic loci
    • Schizophrenia Working Group of the Psychiatric Genomics Consortium
    • Schizophrenia Working Group of the Psychiatric Genomics Consortium. Biological insights from 108 schizophreniaassociated genetic loci. Nature. 2014;511:421-427.
    • (2014) Nature , vol.511 , pp. 421-427
  • 17
    • 84860351742 scopus 로고    scopus 로고
    • Identification of common variants associated with human hippocampal and intracranial volumes
    • Stein JL, Medland SE, Vasquez AA, et al. Identification of common variants associated with human hippocampal and intracranial volumes. Nat Genet. 2012;44:552-561.
    • (2012) Nat Genet , vol.44 , pp. 552-561
    • Stein, J.L.1    Medland, S.E.2    Vasquez, A.A.3
  • 18
    • 84860326795 scopus 로고    scopus 로고
    • Common variants at 12q14 and 12q24 are associated with hippocampal volume
    • Bis JC, DeCarli C, Smith AV, et al. Common variants at 12q14 and 12q24 are associated with hippocampal volume. Nat Genet. 2012;44:545-551.
    • (2012) Nat Genet , vol.44 , pp. 545-551
    • Bis, J.C.1    DeCarli, C.2    Smith, A.V.3
  • 19
    • 84864485341 scopus 로고    scopus 로고
    • Multiple loci influencing hippocampal degeneration identified by genome scan
    • Alzheimer's disease neuroimaging initiative
    • Melville SA, Buros J, Parrado AR, et al.; Alzheimer's Disease Neuroimaging Initiative. Multiple loci influencing hippocampal degeneration identified by genome scan. Ann Neurol. 2012;72:65-75.
    • (2012) Ann Neurol , vol.72 , pp. 65-75
    • Melville, S.A.1    Buros, J.2    Parrado, A.R.3
  • 20
    • 85010190069 scopus 로고    scopus 로고
    • Novel genetic loci associated with hippocampal volume
    • Hibar DP, Adams HH, Jahanshad N, et al. Novel genetic loci associated with hippocampal volume. Nat Commun. 2017;8:13624.
    • (2017) Nat Commun , vol.8 , pp. 13624
    • Hibar, D.P.1    Adams, H.H.2    Jahanshad, N.3
  • 21
    • 84860342407 scopus 로고    scopus 로고
    • Common variants at 6q22 and 17q21 are associated with intracranial volume
    • Ikram MA, Fornage M, Smith AV, et al. Common variants at 6q22 and 17q21 are associated with intracranial volume. Nat Genet. 2012;44:539-544.
    • (2012) Nat Genet , vol.44 , pp. 539-544
    • Ikram, M.A.1    Fornage, M.2    Smith, A.V.3
  • 22
    • 84989867010 scopus 로고    scopus 로고
    • Novel genetic loci underlying human intracranial volume identified through genome-wide association
    • Dec
    • Adams HH, Hibar DP, Chouraki V, et al. Novel genetic loci underlying human intracranial volume identified through genome-wide association. Nat Neurosci. Dec 2016;19(12):1569-1582.
    • (2016) Nat Neurosci , vol.19 , Issue.12 , pp. 1569-1582
    • Adams, H.H.1    Hibar, D.P.2    Chouraki, V.3
  • 23
    • 84878725018 scopus 로고    scopus 로고
    • Dense genotyping of immune-related disease regions identifies nine new risk loci for primary sclerosing cholangitis
    • UK-PSCSC Consortium; International PSC Study Group; International IBD Genetics Consortium
    • Liu JZ, Hov JR, Folseraas T, et al.; UK-PSCSC Consortium; International PSC Study Group; International IBD Genetics Consortium. Dense genotyping of immune-related disease regions identifies nine new risk loci for primary sclerosing cholangitis. Nat Genet. 2013;45:670-675.
    • (2013) Nat Genet , vol.45 , pp. 670-675
    • Liu, J.Z.1    Hov, J.R.2    Folseraas, T.3
  • 24
    • 84946593489 scopus 로고    scopus 로고
    • New statistical approaches exploit the polygenic architecture of schizophrenia-implications for the underlying neurobiology
    • Schork AJ, Wang Y, Thompson WK, Dale AM, Andreassen OA. New statistical approaches exploit the polygenic architecture of schizophrenia-implications for the underlying neurobiology. Curr Opin Neurobiol. 2016;36:89-98.
    • (2016) Curr Opin Neurobiol , vol.36 , pp. 89-98
    • Schork, A.J.1    Wang, Y.2    Thompson, W.K.3    Dale, A.M.4    Andreassen, O.A.5
  • 25
    • 84892659999 scopus 로고    scopus 로고
    • Boosting the power of schizophrenia genetics by leveraging new statistical tools
    • Andreassen OA, Thompson WK, Dale AM. Boosting the power of schizophrenia genetics by leveraging new statistical tools. Schizophr Bull. 2014;40:13-17.
    • (2014) Schizophr Bull , vol.40 , pp. 13-17
    • Andreassen, O.A.1    Thompson, W.K.2    Dale, A.M.3
  • 26
    • 84876834541 scopus 로고    scopus 로고
    • Improved detection of common variants associated with schizophrenia and bipolar disorder using pleiotropy-informed conditional false discovery rate
    • Psychiatric Genomics Consortium (PGC); Bipolar Disorder and Schizophrenia Working Groups
    • Andreassen OA, Thompson WK, Schork AJ, et al.; Psychiatric Genomics Consortium (PGC); Bipolar Disorder and Schizophrenia Working Groups. Improved detection of common variants associated with schizophrenia and bipolar disorder using pleiotropy-informed conditional false discovery rate. PLoS Genet. 2013;9:e1003455.
    • (2013) PLoS Genet , vol.9 , pp. e1003455
    • Andreassen, O.A.1    Thompson, W.K.2    Schork, A.J.3
  • 27
    • 84926348812 scopus 로고    scopus 로고
    • Genetic pleiotropy between multiple sclerosis and schizophrenia but not bipolar disorder: Differential involvement of immune related gene loci
    • Feb
    • Andreassen OA, Harbo HF, Wang Y, et al. Genetic pleiotropy between multiple sclerosis and schizophrenia but not bipolar disorder: differential involvement of immune related gene loci. Mol Psychiatry. Feb 2015;20(2):207-214.
    • (2015) Mol Psychiatry , vol.20 , Issue.2 , pp. 207-214
    • Andreassen, O.A.1    Harbo, H.F.2    Wang, Y.3
  • 28
    • 84873701087 scopus 로고    scopus 로고
    • Improved detection of common variants associated with schizophrenia by leveraging pleiotropy with cardiovascular-disease risk factors
    • Andreassen OA, Djurovic S, Thompson WK, et al. Improved detection of common variants associated with schizophrenia by leveraging pleiotropy with cardiovascular-disease risk factors. Am J Hum Genet. 2013;92:197-209.
    • (2013) Am J Hum Genet , vol.92 , pp. 197-209
    • Andreassen, O.A.1    Djurovic, S.2    Thompson, W.K.3
  • 29
    • 85019761718 scopus 로고    scopus 로고
    • Identification of genetic loci shared between schizophrenia and the big five personality traits
    • Smeland OB, Wang Y, Lo MT, et al. Identification of genetic loci shared between schizophrenia and the big five personality traits. Sci Rep. 2017;7:2222.
    • (2017) Sci Rep , vol.7 , pp. 2222
    • Smeland, O.B.1    Wang, Y.2    Lo, M.T.3
  • 30
    • 85030627618 scopus 로고    scopus 로고
    • Identification of genetic loci jointly influencing schizophrenia risk and the cognitive traits of verbal-numerical reasoning, reaction time, and general cognitive function
    • July 26 2017
    • Smeland OB, Frei O, Kauppi K, et al. Identification of genetic loci jointly influencing schizophrenia risk and the cognitive traits of verbal-numerical reasoning, reaction time, and general cognitive function. JAMA Psychiatry. July 26 2017. doi:10.1001/jamapsychiatry.2017.1986
    • JAMA Psychiatry
    • Smeland, O.B.1    Frei, O.2    Kauppi, K.3
  • 31
    • 84936161018 scopus 로고    scopus 로고
    • Polygenic overlap between c-reactive protein, plasma lipids and Alzheimer's disease
    • Desikan RS, Schork AJ, Wang Y, et al. Polygenic overlap between c-reactive protein, plasma lipids and alzheimer's disease. Circulation. Jun 09 2015;131(23):2061-2069.
    • Circulation. Jun 09 2015 , vol.131 , Issue.23 , pp. 2061-2069
    • Desikan, R.S.1    Schork, A.J.2    Wang, Y.3
  • 32
    • 85019680173 scopus 로고    scopus 로고
    • Identification of gene loci that overlap between schizophrenia and educational attainment
    • Schizophrenia Working Group of the Psychiatric Genomics Consortium
    • Le Hellard S, Wang Y, Witoelar A, et al.; Schizophrenia Working Group of the Psychiatric Genomics Consortium. Identification of gene loci that overlap between schizophrenia and educational attainment. Schizophr Bull. 2017;43:654-664.
    • (2017) Schizophr Bull , vol.43 , pp. 654-664
    • Le Hellard, S.1    Wang, Y.2    Witoelar, A.3
  • 33
    • 84959158225 scopus 로고    scopus 로고
    • Genetic influences on schizophrenia and subcortical brain volumes: Large-scale proof of concept
    • Schizophrenia Working Group of the Psychiatric Genomics Consortium; ENIGMA Consortium
    • Franke B, Stein JL, Ripke S, et al.; Schizophrenia Working Group of the Psychiatric Genomics Consortium; ENIGMA Consortium. Genetic influences on schizophrenia and subcortical brain volumes: large-scale proof of concept. Nat Neurosci. 2016;19:420-431.
    • (2016) Nat Neurosci , vol.19 , pp. 420-431
    • Franke, B.1    Stein, J.L.2    Ripke, S.3
  • 34
    • 68449086236 scopus 로고    scopus 로고
    • Common polygenic variation contributes to risk of schizophrenia and bipolar disorder
    • Purcell SM, Wray NR, Stone JL, et al. Common polygenic variation contributes to risk of schizophrenia and bipolar disorder. Nature. 2009;460:748-752.
    • (2009) Nature , vol.460 , pp. 748-752
    • Purcell, S.M.1    Wray, N.R.2    Stone, J.L.3
  • 35
    • 84923946495 scopus 로고    scopus 로고
    • LD Score regression distinguishes confounding from polygenicity in genome-wide association stuDies
    • Schizophrenia Working Group of the Psychiatric Genomics Consortium
    • Bulik-SulliVan BK, Loh PR, Finucane HK, et al.; Schizophrenia Working Group of the Psychiatric Genomics Consortium. LD Score regression distinguishes confounding from polygenicity in genome-wide association stuDies. Nat Genet. 2015;47:291-295.
    • (2015) Nat Genet , vol.47 , pp. 291-295
    • Bulik-SulliVan, B.K.1    Loh, P.R.2    Finucane, H.K.3
  • 36
    • 84929459112 scopus 로고    scopus 로고
    • Abundant genetic overlap between blood lipids and immune-mediated diseases indicates shared molecular genetic mechanisms
    • Andreassen OA, Desikan RS, Wang Y, et al. Abundant genetic overlap between blood lipids and immune-mediated diseases indicates shared molecular genetic mechanisms. PLoS One. 2015;10:e0123057.
    • (2015) PLoS One , vol.10 , pp. e0123057
    • Andreassen, O.A.1    Desikan, R.S.2    Wang, Y.3
  • 37
    • 84876847154 scopus 로고    scopus 로고
    • All SNPs are not created equal: Genome-wide association stuDies reveal a consistent pattern of enrichment among functionally annotated SNPs
    • Schork AJ, Thompson WK, Pham P, et al. All SNPs are not created equal: genome-wide association stuDies reveal a consistent pattern of enrichment among functionally annotated SNPs. PLoS Genet. 2013;9:e1003449.
    • (2013) PLoS Genet , vol.9 , pp. e1003449
    • Schork, A.J.1    Thompson, W.K.2    Pham, P.3
  • 38
    • 0001677717 scopus 로고
    • Controlling the false discovery rate: A practical and powerful approach to multiple testing
    • Benjamini Y, Hochberg Y. Controlling the false discovery rate: a practical and powerful approach to multiple testing. J R Stat Soc Ser B Methodol. 1995;57:289-300.
    • (1995) J R Stat Soc ser B Methodol , vol.57 , pp. 289-300
    • Benjamini, Y.1    Hochberg, Y.2
  • 39
    • 79952159600 scopus 로고    scopus 로고
    • The effect of correlation in false discovery rate estimation
    • Schwartzman A, Lin X. The effect of correlation in false discovery rate estimation. Biometrika. 2011;98:199-214.
    • (2011) Biometrika , vol.98 , pp. 199-214
    • Schwartzman, A.1    Lin, X.2
  • 41
    • 80054993342 scopus 로고    scopus 로고
    • Spatio-temporal transcriptome of the human brain
    • Kang HJ, Kawasawa YI, Cheng F, et al. Spatio-temporal transcriptome of the human brain. Nature. 2011;478:483-489.
    • (2011) Nature , vol.478 , pp. 483-489
    • Kang, H.J.1    Kawasawa, Y.I.2    Cheng, F.3
  • 42
    • 84878682420 scopus 로고    scopus 로고
    • The genotype-tissue expression (GTEx) project
    • GTEx Consortium
    • GTEx Consortium. The genotype-tissue expression (GTEx) project. Nat Genet. 2013;45:580-585.
    • (2013) Nat Genet , vol.45 , pp. 580-585
  • 43
    • 84921750431 scopus 로고    scopus 로고
    • Genetic variability in the regulation of gene expression in ten regions of the human brain
    • UK Brain Expression Consortium; North American Brain Expression Consortium
    • Ramasamy A, Trabzuni D, Guelfi S, et al.; UK Brain Expression Consortium; North American Brain Expression Consortium. Genetic variability in the regulation of gene expression in ten regions of the human brain. Nat Neurosci. 2014;17:1418-1428.
    • (2014) Nat Neurosci , vol.17 , pp. 1418-1428
    • Ramasamy, A.1    Trabzuni, D.2    Guelfi, S.3
  • 44
    • 0033837078 scopus 로고    scopus 로고
    • Normal brain development and aging: Quantitative analysis at in vivo MR imaging in healthy volunteers
    • Courchesne E, Chisum HJ, Townsend J, et al. Normal brain development and aging: quantitative analysis at in vivo MR imaging in healthy volunteers. Radiology. 2000;216:672-682.
    • (2000) Radiology , vol.216 , pp. 672-682
    • Courchesne, E.1    Chisum, H.J.2    Townsend, J.3
  • 45
    • 84922465421 scopus 로고    scopus 로고
    • GWAS of longevity in CHARGE consortium confirms APOE and FOXO3 candidacy
    • Broer L, Buchman AS, Deelen J, et al. GWAS of longevity in CHARGE consortium confirms APOE and FOXO3 candidacy. J Gerontol A Biol Sci Med Sci. 2015;70:110-118.
    • (2015) J Gerontol A Biol Sci Med Sci , vol.70 , pp. 110-118
    • Broer, L.1    Buchman, A.S.2    Deelen, J.3
  • 46
    • 85020899420 scopus 로고    scopus 로고
    • Genome-wide association meta-analysis of 78,308 individuals identifies new loci and genes influencing human intelligence
    • Sniekers S, Stringer S, Watanabe K, et al. Genome-wide association meta-analysis of 78,308 individuals identifies new loci and genes influencing human intelligence. Nat Genet. Jul 2017;49(7):1107-1112.
    • Nat Genet. Jul 2017 , vol.49 , Issue.7 , pp. 1107-1112
    • Sniekers, S.1    Stringer, S.2    Watanabe, K.3
  • 47
    • 84872899284 scopus 로고    scopus 로고
    • FOXOs: Signalling integrators for homeostasis maintenance
    • Eijkelenboom A, Burgering BM. FOXOs: signalling integrators for homeostasis maintenance. Nat Rev Mol Cell Biol. 2013;14:83-97.
    • (2013) Nat Rev Mol Cell Biol , vol.14 , pp. 83-97
    • Eijkelenboom, A.1    Burgering, B.M.2
  • 49
    • 84870381375 scopus 로고    scopus 로고
    • Expression of constitutively active FoxO3 in murine forebrain leads to a loss of neural progenitors
    • Schmidt-Strassburger U, Schips TG, Maier HJ, et al. Expression of constitutively active FoxO3 in murine forebrain leads to a loss of neural progenitors. FASEB J. 2012;26:4990-5001.
    • (2012) FASEB J , vol.26 , pp. 4990-5001
    • Schmidt-Strassburger, U.1    Schips, T.G.2    Maier, H.J.3
  • 50
    • 84949742039 scopus 로고    scopus 로고
    • Loci with genome-wide associations with schizophrenia in the Han Chinese population
    • Li Z, Xiang Y, Chen J, et al. Loci with genome-wide associations with schizophrenia in the Han Chinese population. Br J Psychiatry. 2015;207:490-494.
    • (2015) Br J Psychiatry , vol.207 , pp. 490-494
    • Li, Z.1    Xiang, Y.2    Chen, J.3
  • 51
    • 33646909090 scopus 로고    scopus 로고
    • Quantification of fragments of human serum inter-alpha-trypsin inhibitor heavy chain 4 by a surface-enhanced laser desorption/ionization-based immunoassay
    • Song J, Patel M, Rosenzweig CN, et al. Quantification of fragments of human serum inter-alpha-trypsin inhibitor heavy chain 4 by a surface-enhanced laser desorption/ionization-based immunoassay. Clin Chem. 2006;52:1045-1053.
    • (2006) Clin Chem , vol.52 , pp. 1045-1053
    • Song, J.1    Patel, M.2    Rosenzweig, C.N.3
  • 52
    • 84961233618 scopus 로고    scopus 로고
    • Schizophrenia risk variants in ITIH4 and CALN1 regulate gene expression in the dorsolateral prefrontal cortex
    • Ohi K, Shimada T, Nitta Y, et al. Schizophrenia risk variants in ITIH4 and CALN1 regulate gene expression in the dorsolateral prefrontal cortex. Psychiatr Genet. 2016;26:142-143.
    • (2016) Psychiatr Genet , vol.26 , pp. 142-143
    • Ohi, K.1    Shimada, T.2    Nitta, Y.3
  • 53
    • 38349190204 scopus 로고    scopus 로고
    • Mice with targeted Slc4a10 gene disruption have small brain ventricles and show reduced neuronal excitability
    • Jacobs S, Ruusuvuori E, Sipila ST, et al. Mice with targeted Slc4a10 gene disruption have small brain ventricles and show reduced neuronal excitability. Proc Natl Acad Sci U S A. 2008;105:311-316.
    • (2008) Proc Natl Acad Sci U S A , vol.105 , pp. 311-316
    • Jacobs, S.1    Ruusuvuori, E.2    Sipila, S.T.3
  • 54
    • 33644618433 scopus 로고    scopus 로고
    • The biology of incretin hormones
    • Drucker DJ. The biology of incretin hormones. Cell Metab. 2006;3:153-165.
    • (2006) Cell Metab , vol.3 , pp. 153-165
    • Drucker, D.J.1
  • 56
    • 79958246447 scopus 로고    scopus 로고
    • The netrin receptor DCC is required in the pubertal organization of mesocortical dopamine circuitry
    • Manitt C, Mimee A, Eng C, et al. The netrin receptor DCC is required in the pubertal organization of mesocortical dopamine circuitry. J Neurosci. 2011;31:8381-8394.
    • (2011) J Neurosci , vol.31 , pp. 8381-8394
    • Manitt, C.1    Mimee, A.2    Eng, C.3
  • 58
    • 84860839588 scopus 로고    scopus 로고
    • Association between schizophrenia and genetic variation in DCC: A case-control study
    • Grant A, Fathalli F, Rouleau G, Joober R, Flores C. Association between schizophrenia and genetic variation in DCC: a case-control study. Schizophr Res. 2012;137:26-31.
    • (2012) Schizophr Res , vol.137 , pp. 26-31
    • Grant, A.1    Fathalli, F.2    Rouleau, G.3    Joober, R.4    Flores, C.5
  • 59
    • 84856225986 scopus 로고    scopus 로고
    • De novo CNV analysis implicates specific abnormalities of postsynaptic signaling complexes in the pathogenesis of schizophrenia
    • Kirov G, Pocklington AJ, Holmans P, et al. De novo CNV analysis implicates specific abnormalities of postsynaptic signaling complexes in the pathogenesis of schizophrenia. Mol Psychiatry. 2012;17:142-153.
    • (2012) Mol Psychiatry , vol.17 , pp. 142-153
    • Kirov, G.1    Pocklington, A.J.2    Holmans, P.3
  • 60
    • 84871712720 scopus 로고    scopus 로고
    • Synaptic scaffold evolution generated components of vertebrate cognitive complexity
    • Nithianantharajah J, Komiyama NH, McKechanie A, et al. Synaptic scaffold evolution generated components of vertebrate cognitive complexity. Nat Neurosci. 2013;16:16-24.
    • (2013) Nat Neurosci , vol.16 , pp. 16-24
    • Nithianantharajah, J.1    Komiyama, N.H.2    McKechanie, A.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.