Schizophrenia risk variants in ITIH4 and CALN1 regulate gene expression in the dorsolateral prefrontal cortex

Psychiatric Genetics

Volumn 26, Issue 3, 2016, Pages 142-143

  Ohi, Kazutaka ^a   Shimada, Takamitsu ^a   Nitta, Yusuke ^a   Kihara, Hiroaki ^a   Okubo, Hiroaki ^a   Uehara, Takashi ^a   Kawasaki, Yasuhiro ^a  

^a KANAZAWA MEDICAL UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

CALN1 GENE; DISEASE PREDISPOSITION; DORSOLATERAL PREFRONTAL CORTEX; GENE; GENE EXPRESSION; GENE EXPRESSION REGULATION; GENETIC ASSOCIATION; GENETIC RISK; GENOME; GENOME-WIDE ASSOCIATION STUDY; HUMAN; ITIH4 GENE; LETTER; PHENOTYPE; PRIORITY JOURNAL; QUANTITATIVE TRAIT LOCUS; SCHIZOPHRENIA; SINGLE NUCLEOTIDE POLYMORPHISM; GENETICS; METABOLISM; PREFRONTAL CORTEX;

CALMODULIN; CALN1 PROTEIN, HUMAN; GLYCOPROTEIN; ITIH4 PROTEIN, HUMAN; LEUKOCYTE ELASTASE INHIBITOR; PLASMA PROTEIN;

BLOOD PROTEINS; CALMODULIN; GENE EXPRESSION REGULATION; GLYCOPROTEINS; HUMANS; PREFRONTAL CORTEX; PROTEINASE INHIBITORY PROTEINS, SECRETORY; SCHIZOPHRENIA;

EID: 84961233618     PISSN: 09558829     EISSN: 14735873     Source Type: Journal    
DOI: 10.1097/YPG.0000000000000127     Document Type: Letter

References (5)

1. Colantuoni C, Lipska BK, Ye T, Hyde TM, Tao R, Leek JT, et al. (2011). Temporal dynamics and genetic control of transcription in the human prefrontal cortex. Nature 478:519-523.
2. Hamshere ML, Walters JT, Smith R, Richards AL, Green E, Grozeva D, et al. (2013). Genome-wide significant associations in schizophrenia to ITIH3/4, CACNA1C and SDCCAG8, and extensive replication of associations reported by the schizophrenia PGC. Mol Psychiatry 18:708-712.
3. Li Z, Xiang Y, Chen J, Li Q, Shen J, Liu Y, et al. (2015). Loci with genome-wide associations with schizophrenia in the Han Chinese population. Br J Psychiatry 207:490-494.
4. Ripke S, Sanders AR, Kendler KS, Levinson DF, Sklar P, Holmans PA, et al., Schizophrenia Psychiatric Genome-Wide Association Study (GWAS) Consortium (2011). Genome-wide association study identifies five new schizophrenia loci. Nat Genet 43:969-976.
5. Ripke S, Neale BM, Corvin A, Walters JT, Farh KH, Holmans PA, et al., Schizophrenia Working Group of the Psychiatric Genomics Consortium (2014). Biological insights from 108 schizophrenia-associated genetic loci. Nature 511:421-427.